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M. Bobardt · SciRah

Researcher profile · Semantic Scholar

M. Bobardt

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M. Bobardt — researcher profile on SciRah

h-index: 31
Works: 82
Citations: 3,524

Most-cited papers

Syndecans Serve as Attachment Receptors for Human Immunodeficiency Virus Type 1 on Macrophages
Andrew C. S. Saphire, M. Bobardt, Zhe Zhang, G. David +1 more
2001Journal of Virology281 citations Open access
Semantic Scholar
The cyclophilin inhibitor Debio‐025 shows potent anti–hepatitis C effect in patients coinfected with hepatitis C and human immunodeficiency virus
R. Flisiak, A. Horban, P. Gallay, M. Bobardt +13 more
2008Hepatology233 citations Open access
Semantic Scholar
Syndecan captures, protects, and transmits HIV to T lymphocytes.
M. Bobardt, Andrew C. S. Saphire, Hsiu-Cheng Hung, Xiaocong Yu +4 more
2003Immunity226 citations Open access
Semantic Scholar
The Isomerase Active Site of Cyclophilin A Is Critical for Hepatitis C Virus Replication*
U. Chatterji, M. Bobardt, S. Selvarajah, Feng Yang +5 more
2009Journal of Biological Chemistry211 citations Open access
Semantic Scholar
DEB025 (Alisporivir) Inhibits Hepatitis C Virus Replication by Preventing a Cyclophilin A Induced Cis-Trans Isomerisation in Domain II of NS5A
Lotte Coelmont, X. Hanoulle, U. Chatterji, C. Berger +11 more
2010PLoS ONE195 citations Open access
Semantic Scholar
Cell-Free Human Immunodeficiency Virus Type 1 Transcytosis through Primary Genital Epithelial Cells
M. Bobardt, U. Chatterji, S. Selvarajah, B. van der Schueren +3 more
2006Journal of Virology193 citations Open access
Semantic Scholar
Syndecan-3 is a dendritic cell-specific attachment receptor for HIV-1
L. de Witte, M. Bobardt, U. Chatterji, G. Degeest +3 more
2007Proceedings of the National Academy of Sciences of the United States of America182 citations Open access
Semantic Scholar
Contribution of Proteoglycans to Human Immunodeficiency Virus Type 1 Brain Invasion
M. Bobardt, P. Salmon, Lian-Chun Wang, J. Esko +6 more
2004Journal of Virology130 citations Open access
Semantic Scholar
Inhibition of HIV Env binding to cellular receptors by monoclonal antibody 2G12 as probed by Fc-tagged gp120
J. Binley, S. Ngo-Abdalla, Penny Moore, M. Bobardt +6 more
2006Retrovirology128 citations Open access
Semantic Scholar
HCV RESISTANCE TO CYCLOSPORIN A DOES NOT CORRELATE WITH A RESISTANCE OF THE NS5A-CYCLOPHILIN A INTERACTION TO CYCLOPHILIN INHIBITORS
U. Chatterji, Precious J. Lim, M. Bobardt, S. Wieland +7 more
2010Journal of Hepatology125 citations Open access
Semantic Scholar
Tolerance-related V beta clonal deletions in normal CD4-8-, TCR- alpha/beta + and abnormal lpr and gld cell populations
P. Singer, Robert S. Balderas, R. J. McEvilly, M. Bobardt +1 more
1989Journal of Experimental Medicine117 citations Open access
Semantic Scholar
Inhibition of Human Immunodeficiency Virus Type 1 Replication in Human Cells by Debio-025, a Novel Cyclophilin Binding Agent
R. Ptak, P. Gallay, Dirk Jochmans, A. Halestrap +11 more
2008Antimicrobial Agents and Chemotherapy110 citations Open access
Semantic Scholar
A Highly Conserved Arginine in gp120 Governs HIV-1 Binding to Both Syndecans and CCR5 via Sulfated Motifs*
A. de Parseval, M. Bobardt, A. Chatterji, U. Chatterji +6 more
2005Journal of Biological Chemistry87 citations Open access
Semantic Scholar
Naturally Occurring Capsid Substitutions Render HIV-1 Cyclophilin A Independent in Human Cells and TRIM-cyclophilin-resistant in Owl Monkey Cells*
U. Chatterji, M. Bobardt, R. Stanfield, R. Ptak +9 more
2005Journal of Biological Chemistry81 citations Open access
Semantic Scholar
Hepatitis C virus NS5A anchor peptide disrupts human immunodeficiency virus
M. Bobardt, G. Cheng, L. de Witte, S. Selvarajah +5 more
2008Proceedings of the National Academy of Sciences of the United States of America80 citations Open access
Semantic Scholar
Trim5α Accelerates Degradation of Cytosolic Capsid Associated with Productive HIV-1 Entry*
U. Chatterji, M. Bobardt, P. Gaskill, Dennis A. Sheeter +2 more
2006Journal of Biological Chemistry74 citations Open access
Semantic Scholar
Alisporivir Inhibition of Hepatocyte Cyclophilins Reduces HBV Replication and Hepatitis B Surface Antigen Production
S. Phillips, S. Chokshi, U. Chatterji, A. Riva +4 more
2014Gastroenterology58 citations Open access
Semantic Scholar
Cyclophilin and NS5A Inhibitors, but Not Other Anti-Hepatitis C Virus (HCV) Agents, Preclude HCV-Mediated Formation of Double-Membrane-Vesicle Viral Factories
U. Chatterji, M. Bobardt, Andrew W. Tai, M. Wood +1 more
2015Antimicrobial Agents and Chemotherapy55 citations Open access
Semantic Scholar
A robust SARS-CoV-2 replication model in primary human epithelial cells at the air liquid interface to assess antiviral agents
Thuc Nguyen Dan Do, Kim Donckers, Laura Vangeel, A. Chatterjee +7 more
2021bioRxiv54 citations Open access
Semantic Scholar
The Cyclophilin Inhibitor SCY-635 Disrupts Hepatitis C Virus NS5A-Cyclophilin A Complexes
S. Hopkins, M. Bobardt, U. Chatterji, Jose A. Garcia-Rivera +2 more
2012Antimicrobial Agents and Chemotherapy53 citations Open access
Semantic Scholar
A Pan-Cyclophilin Inhibitor, CRV431, Decreases Fibrosis and Tumor Development in Chronic Liver Disease Models
Joseph Kuo, M. Bobardt, U. Chatterji, P. Mayo +4 more
2019Journal of Pharmacology and Experimental Therapeutics49 citations Open access
Semantic Scholar
Multiple Mutations in Hepatitis C Virus NS5A Domain II Are Required To Confer a Significant Level of Resistance to Alisporivir
Jose A. Garcia-Rivera, M. Bobardt, U. Chatterji, S. Hopkins +4 more
2012Antimicrobial Agents and Chemotherapy45 citations Open access
Semantic Scholar
Preclinical Characterization of Naturally Occurring Polyketide Cyclophilin Inhibitors from the Sanglifehrin Family
M. Gregory, M. Bobardt, Susan Obeid, U. Chatterji +13 more
2011Antimicrobial Agents and Chemotherapy45 citations Open access
Semantic Scholar
Human immunodeficiency virus type 1 hijacks host cyclophilin A for its attachment to target cells
Andrew C. S. Saphire, M. Bobardt, P. Gallay
2000Immunologic research42 citations
Semantic Scholar
The cyclophilin inhibitor CRV431 inhibits liver HBV DNA and HBsAg in transgenic mice
P. Gallay, D. Ure, M. Bobardt, U. Chatterji +3 more
2019PLoS ONE39 citations Open access
Semantic Scholar
The Novel Cyclophilin Inhibitor CPI-431-32 Concurrently Blocks HCV and HIV-1 Infections via a Similar Mechanism of Action
P. Gallay, M. Bobardt, U. Chatterji, D. Trepanier +3 more
2015PLoS ONE37 citations Open access
Semantic Scholar
Cyclophilin A-independent recruitment of NS5A and NS5B into hepatitis C virus replication complexes.
U. Chatterji, M. Bobardt, Precious J. Lim, P. Gallay
2010Journal of General Virology37 citations Open access
Semantic Scholar
Virucidal and antiviral activity of astodrimer sodium against SARS-CoV-2 in vitro
J. Paull, Graham P Heery, M. Bobardt, A. Castellarnau +3 more
2021Antiviral Research33 citations Open access
Semantic Scholar
The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate
M. Bobardt, Joseph Kuo, U. Chatterji, S. Chanda +4 more
2019PLoS ONE33 citations Open access
Semantic Scholar
PD 404,182 Is a Virocidal Small Molecule That Disrupts Hepatitis C Virus and Human Immunodeficiency Virus
Ana Maria Chamoun, K. Chockalingam, M. Bobardt, Rudo L. Simeon +3 more
2011Antimicrobial Agents and Chemotherapy33 citations Open access
Semantic Scholar
Cyclophilin A Plays Distinct Roles in Human Immunodeficiency Virus Type 1 Entry and Postentry Events, as Revealed by Spinoculation
Andrew C. S. Saphire, M. Bobardt, P. Gallay
2002Journal of Virology31 citations Open access
Semantic Scholar
HCV NS5A and IRF9 Compete For CypA Binding
M. Bobardt, S. Hopkins, James M Baugh, U. Chatterji +5 more
2012Journal of Hepatology28 citations Open access
Semantic Scholar
trans-Complementation Rescue of Cyclophilin A-Deficient Viruses Reveals that the Requirement for Cyclophilin A in Human Immunodeficiency Virus Type 1 Replication Is Independent of Its Isomerase Activity
Andrew C. S. Saphire, M. Bobardt, P. Gallay
2002Journal of Virology28 citations Open access
Semantic Scholar
Protective Effects of Astodrimer Sodium 1% Nasal Spray Formulation against SARS-CoV-2 Nasal Challenge in K18-hACE2 Mice
J. Paull, C. Luscombe, A. Castellarnau, Graham P Heery +2 more
2021Viruses27 citations Open access
Semantic Scholar
HSV Neutralization by the Microbicidal Candidate C5A
L. de Witte, M. Bobardt, U. Chatterji, F. V. van Loenen +3 more
2011PLoS ONE26 citations Open access
Semantic Scholar
HCV Core Residues Critical for Infectivity Are Also Involved in Core-NS5A Complex Formation
K. Gawlik, James M Baugh, U. Chatterji, Precious J. Lim +2 more
2014PLoS ONE25 citations Open access
Semantic Scholar
Effect of polyanion-resistance on HIV-1 infection.
M. Bobardt, Mercedes Armand-Ugón, I. Clotet, Zhe Zhang +3 more
2004Virology23 citations Open access
Semantic Scholar
Syndecan-Fc Hybrid Molecule as a Potent In Vitro Microbicidal Anti-HIV-1 Agent
M. Bobardt, U. Chatterji, L. Schaffer, L. de Witte +1 more
2010Antimicrobial Agents and Chemotherapy21 citations Open access
Semantic Scholar
Selective modulation of elements of the immune system by low molecular weight nucleosides.
Michael G. Goodman, Allen B. Reitz, R. Chen, M. Bobardt +2 more
1995Journal of Pharmacology and Experimental Therapeutics21 citations
Semantic Scholar
Sangamides, a new class of cyclophilin-inhibiting host-targeted antivirals for treatment of HCV infection
S. Moss, M. Bobardt, P. Leyssen, N. Coates +13 more
201218 citations
Semantic Scholar
Correlation of Naturally Occurring HIV-1 Resistance to DEB025 with Capsid Amino Acid Polymorphisms
P. Gallay, R. Ptak, M. Bobardt, J. Dumont +2 more
2013Viruses16 citations Open access
Semantic Scholar
88 PARTICULAR IN VITRO ANTI-HCV ACTIVITIES AND RESISTANCE PROFILE OF THE CYCLOPHILIN INHIBITOR DEBIO 025
Lotte Coelmont, P. Gallay, M. Bobardt, Suzanne J. F. Kaptein +4 more
200916 citations Open access
Semantic Scholar
Post-infection treatment with the E protein inhibitor BIT225 reduces disease severity and increases survival of K18-hACE2 transgenic mice infected with a lethal dose of SARS-CoV-2
G. Ewart, M. Bobardt, B. Bentzen, Yannan Yan +6 more
2023bioRxiv15 citations Open access
Semantic Scholar
Evaluation of PD 404,182 as an Anti-HIV and Anti-Herpes Simplex Virus Microbicide
A. Chamoun-Emanuelli, M. Bobardt, B. Moncla, Marie K. Mankowski +3 more
2013Antimicrobial Agents and Chemotherapy13 citations Open access
Semantic Scholar
Structurally distinct cyclosporin and sanglifehrin analogs CRV431 and NV556 suppress established HCV infection in humanized-liver mice
M. Bobardt, M. Hansson, P. Mayo, D. Ure +2 more
2020PLoS ONE11 citations Open access
Semantic Scholar
Cyclophilin Inhibitors Remodel the Endoplasmic Reticulum of HCV-Infected Cells in a Unique Pattern Rendering Cells Impervious to a Reinfection
U. Chatterji, M. Bobardt, L. Schaffer, M. Wood +1 more
2016PLoS ONE11 citations Open access
Semantic Scholar
Mice lacking cyclophilin B, but not cyclophilin A, are protected from the development of NASH in a diet and chemical-induced model
Winston T. Stauffer, Asha Z. Goodman, M. Bobardt, D. Ure +2 more
2024PLoS ONE9 citations Open access
Semantic Scholar
C5A Protects Macaques from Vaginal Simian-Human Immunodeficiency Virus Challenge
R. Veazey, U. Chatterji, M. Bobardt, Kasi E. Russell-Lodrigue +3 more
2015Antimicrobial Agents and Chemotherapy9 citations Open access
Semantic Scholar
Both Cyclophilin Inhibitors and Direct-Acting Antivirals Prevent PKR Activation in HCV-Infected Cells
M. Bobardt, U. Chatterji, Precious J. Lim, K. Gawlik +1 more
2014Open Virology Journal9 citations Open access
Semantic Scholar
Sustained Local Delivery of Structurally Diverse HIV-1 Microbicides Released from Sublimation Enthalpy Controlled Matrices
S. Gunaseelan, P. Gallay, M. Bobardt, C. Dezzutti +2 more
2012Pharmaceutical Research9 citations Open access
Semantic Scholar

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