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M. Mccourt · SciRah

Researcher profile · Semantic Scholar

M. Mccourt

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M. Mccourt — researcher profile on SciRah

h-index: 10
Works: 26
Citations: 1,068

Most-cited papers

Rational Selection of Syngeneic Preclinical Tumor Models for Immunotherapeutic Drug Discovery
Suzanne Mosely, J. Prime, R. Sainson, J. Koopmann +20 more
2016Cancer immunology research352 citations Open access
Semantic Scholar
Preclinical and Clinical Studies of MMP Inhibitors in Cancer
A. Drummond, P. Beckett, P. Brown, E. Bone +9 more
1999Annals of the New York Academy of Sciences222 citations
Semantic Scholar
Mobilization of early hematopoietic progenitor cells with BB-10010: a genetically engineered variant of human macrophage inflammatory protein-1 alpha.
B. Lord, L. Woolford, L. Wood, Lloyd G. Czaplewski +3 more
1995Blood123 citations
Semantic Scholar
Combining TGF-beta inhibition and angiotensin II blockade results in enhanced antifibrotic effect.
Ling Yu, W. Border, I. Anderson, M. Mccourt +2 more
2004Kidney International105 citations Open access
Semantic Scholar
BB-10010: an active variant of human macrophage inflammatory protein-1 alpha with improved pharmaceutical properties.
M. Hunter, L. Bawden, D. Brotherton, S. Craig +12 more
1995Blood71 citations
Semantic Scholar
A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions
C. Grütter, T. Wilkinson, R. Turner, Sadhana Podichetty +5 more
2008Proceedings of the National Academy of Sciences of the United States of America57 citations Open access
Semantic Scholar
An Antibody Targeting ICOS Increases Intratumoral Cytotoxic to Regulatory T-cell Ratio and Induces Tumor Regression
R. Sainson, A. Thotakura, M. Kosmač, Gwenoline Borhis +25 more
2020Cancer immunology research38 citations Open access
Semantic Scholar
A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension
N. Arnold, J. Pickworth, L. West, Sarah Dawson +23 more
2019Nature Communications29 citations Open access
Semantic Scholar
Th1 cytokines are more effective than Th2 cytokines at licensing anti‐tumour functions in CD40‐activated human macrophages in vitro
Nadia M. Luheshi, G. Davies, Edmund Poon, Kimberley A. Wiggins +2 more
2014European Journal of Immunology28 citations
Semantic Scholar
Improved drug-like properties of therapeutic proteins by directed evolution
A. Buchanan, Franco Ferraro, Steven J Rust, S. Sridharan +5 more
2012Protein engineering, design & selection : PEDS24 citations Open access
Semantic Scholar
Abstract LB-158: MEDI4736: Delivering effective blockade of immunosupression to enhance tumour rejection: Monoclonal antibody discovery and preclinical development
R. Stewart, Michelle Morrow, Matthieu Chodorge, D. Marcus +10 more
20119 citations
Semantic Scholar
Abstract LB-153: KY1055, a novel ICOS-PD-L1 bispecific antibody, efficiently enhances T cell activation and delivers a potent anti-tumour response in vivo
R. Sainson, Nahida Parveen, Gwenoline Borhis, M. Kosmač +7 more
2018Clinical research6 citations
Semantic Scholar
Abstract 2792: The combination of immune checkpoint blockers with the anti-ICOS KY1044 antibody results in a strong tumor response
R. Sainson, M. Mccourt, A. Thotakura, Nahida Parveen +10 more
2018Immunology2 citations
Semantic Scholar
A novel antibody targeting ICOS increases intratumoural cytotoxic to regulatory T cell ratio and induces tumour regression
R. Sainson, A. Thotakura, M. Kosmač, Gwenoline Borhis +24 more
20191 citations Open access
Semantic Scholar
Abstract 1542: Th1 and Th2 cytokines determine how CD40 activation changes human macrophage function in vitro.
Nadia M. Luheshi, G. Davies, Eddie K. K. Poon, M. Mccourt +1 more
20131 citations
Semantic Scholar
Abstract 1616: Survivin regulates endothelial cell proliferation, survival and angiogenesis.
C. Eberlein, Grace Opoku-Ansah, J. Legg, Timothy B. London +8 more
20131 citations
Semantic Scholar
Engineering, Biology, and Clinical Development of hMIP-1α
L. Czaplewski, M. Mccourt, M. Hunter, B. Lord +2 more
19991 citations
Semantic Scholar
Abstract 4953: Differential expression of ICOS on circulating immune cells and tumor infiltrating lymphocytes in patient with solid tumors
R. Sainson, M. Kosmač, R. Kimber, J. Carvalho +4 more
2019Immunology0 citations
Semantic Scholar
Anti-pd-1 antibodies
A. Duncan, M. Mccourt, M. Dyson, J. Blackwood
20170 citations
Semantic Scholar
Multispecific antibody with combination therapy for immuno-oncology
Jamie Campbell, N. Sandy, Cassandra Van Krinks, S. Arkinstall +10 more
20170 citations
Semantic Scholar
Anticorps multispécifiques pour l'immuno-oncologie
Jamie Campbell, Nikole Sandy, Cassandra Van Krinks, S. Arkinstall +10 more
20170 citations
Semantic Scholar
Abstract 19805: Development of a Novel Human Anti-OPG Antibody That Attenuates Experimental Pulmonary Arterial Hypertension
N. Arnold, J. Pickworth, J. Carvalho, Adam T. Braithwaite +11 more
20170 citations
Semantic Scholar
Abstract 363: Activin receptor-like kinase 1 (Alk1) ligands modulate endothelial cell function in vitro and in vivo.
G. Davies, J. Harper, R. Sainson, L. Brown +4 more
20130 citations
Semantic Scholar
Abstract 1562: Choosing the right preclinical model for cancer immunotherapy: The “SyngenOmic” toolbox..
J. Harper, J. Prime, A. Herath, J. Howell +8 more
20130 citations
Semantic Scholar
Structure of the Fab Fragment of GC-1008 in Complex with Transforming Growth Factor-Beta 3
T. Wilkinson, R. Turner, S. Podichetty, D. Finch +3 more
20080 citations
Semantic Scholar
In vitro and in vivo characterisation of CAT-192 and 1D11: Neutralising antibodies to transforming growth factor beta
A. Carruthers, D. Abraham, L. Conroy, M. Mccourt +2 more
20020 citations
Semantic Scholar

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