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E. Valli · SciRah

Researcher profile · Semantic Scholar

E. Valli

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E. Valli — researcher profile on SciRah

h-index: 23
Works: 48
Citations: 1,972

Most-cited papers

Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion
Florida Voli, E. Valli, L. Lerra, Kathleen Kimpton +14 more
2020Cancer Research314 citations Open access
Semantic Scholar
SIRT1 Promotes N-Myc Oncogenesis through a Positive Feedback Loop Involving the Effects of MKP3 and ERK on N-Myc Protein Stability
G. Marshall, Pei Y. Liu, S. Gherardi, C. Scarlett +16 more
2011PLoS Genetics156 citations Open access
Semantic Scholar
Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma
Laura D. Gamble, Stefania Purgato, J. Murray, Lin Xiao +29 more
2019Science Translational Medicine140 citations Open access
Semantic Scholar
APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome.
S. Trazzi, V. Mitrugno, E. Valli, C. Fuchs +5 more
2011Human Molecular Genetics115 citations
Semantic Scholar
A SP1/MIZ1/MYCN repression complex recruits HDAC1 at the TRKA and p75NTR promoters and affects neuroblastoma malignancy by inhibiting the cell response to NGF.
N. Iraci, Daniel Diolaiti, A. Papa, Antonio Porro +7 more
2011Cancer Research108 citations Open access
Semantic Scholar
Direct and Coordinate Regulation of ATP-binding Cassette Transporter Genes by Myc Factors Generates Specific Transcription Signatures That Significantly Affect the Chemoresistance Phenotype of Cancer Cells*
Antonio Porro, M. Haber, Daniel Diolaiti, N. Iraci +12 more
2010Journal of Biological Chemistry104 citations Open access
Semantic Scholar
HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder.
S. Trazzi, C. Fuchs, Rocchina Viggiano, Marianna De Franceschi +8 more
2016Human Molecular Genetics99 citations
Semantic Scholar
IKAROS Deletions Dictate a Unique Gene Expression Signature in Patients with Adult B-Cell Acute Lymphoblastic Leukemia
I. Iacobucci, N. Iraci, M. Messina, A. Lonetti +18 more
2012PLoS ONE92 citations Open access
Semantic Scholar
ABCC Multidrug Transporters in Childhood Neuroblastoma: Clinical and Biological Effects Independent of Cytotoxic Drug Efflux
M. Henderson, M. Haber, Antonio Porro, Marcia A. Munoz +19 more
2011Journal of the National Cancer Institute92 citations Open access
Semantic Scholar
Physical Interaction between MYCN Oncogene and Polycomb Repressive Complex 2 (PRC2) in Neuroblastoma
D. Corvetta, O. Chayka, S. Gherardi, C. D'Acunto +5 more
2013Journal of Biological Chemistry67 citations Open access
Semantic Scholar
The DMD Locus Harbours Multiple Long Non-Coding RNAs Which Orchestrate and Control Transcription of Muscle Dystrophin mRNA Isoforms
M. Bovolenta, D. Erriquez, E. Valli, S. Brioschi +9 more
2012PLoS ONE63 citations Open access
Semantic Scholar
Combining Carbon Nanotubes and Chitosan for the Vectorization of Methotrexate to Lung Cancer Cells
G. Cirillo, O. Vittorio, David Kunhardt, E. Valli +5 more
2019Materials56 citations Open access
Semantic Scholar
CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells
E. Valli, S. Trazzi, C. Fuchs, D. Erriquez +3 more
2012Biochimica et Biophysica Acta55 citations Open access
Semantic Scholar
Targeting metabolic activity in high-risk neuroblastoma through Monocarboxylate Transporter 1 (MCT1) inhibition
Aaminah Khan, E. Valli, Hayley Lam, D. Scott +12 more
2020Oncogene51 citations Open access
Semantic Scholar
c-MYC Oncoprotein Dictates Transcriptional Profiles of ATP-Binding Cassette Transporter Genes in Chronic Myelogenous Leukemia CD34+ Hematopoietic Progenitor Cells
Antonio Porro, N. Iraci, S. Soverini, Daniel Diolaiti +12 more
2011Molecular Cancer Research47 citations
Semantic Scholar
MYCN-mediated transcriptional repression in neuroblastoma: the other side of the coin
S. Gherardi, E. Valli, D. Erriquez, G. Perini
2013Frontiers in Oncology46 citations Open access
Semantic Scholar
The Amyloid Precursor Protein (APP) Triplicated Gene Impairs Neuronal Precursor Differentiation and Neurite Development through Two Different Domains in the Ts65Dn Mouse Model for Down Syndrome*
S. Trazzi, C. Fuchs, E. Valli, G. Perini +2 more
2013Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Interplay between MycN and c-Myc regulates radioresistance and cancer stem cell phenotype in neuroblastoma upon glutamine deprivation
M. Le Grand, A. Mukha, J. Püschel, E. Valli +4 more
2020Theranostics41 citations Open access
Semantic Scholar
Magnetic Graphene Oxide Nanocarrier for Targeted Delivery of Cisplatin: A Perspective for Glioblastoma Treatment
S. Makharza, G. Cirillo, O. Vittorio, E. Valli +8 more
2019Pharmaceuticals35 citations Open access
Semantic Scholar
Suppression of the ATP-binding cassette transporter ABCC4 impairs neuroblastoma tumor growth and sensitizes to irinotecan in vivo
J. Murray, E. Valli, Denise M. T. Yu, Alan M Truong +17 more
2017European Journal of Cancer27 citations Open access
Semantic Scholar
Activation of endogenous retroviruses and induction of viral mimicry by MEK1/2 inhibition in pancreatic cancer
A. Cortesi, Francesco Gandolfi, Fabiana Arco, Pierluigi DiChiaro +19 more
2024Science Advances26 citations Open access
Semantic Scholar
MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4
Cheng-Yuan Xue, Denise M. T. Yu, S. Gherardi, J. Koach +12 more
2016OncoTarget25 citations Open access
Semantic Scholar
Chitosan–Quercetin Bioconjugate as Multi‐Functional Component of Antioxidants and Dual‐Responsive Hydrogel Networks
G. Cirillo, M. Curcio, U. G. Spizzirri, O. Vittorio +5 more
2019Macromolecular materials and engineering (Print)24 citations
Semantic Scholar
Copper chelation redirects neutrophil function to enhance anti-GD2 antibody therapy in neuroblastoma
J. Rouaen, Antonietta Salerno, T. Shai-Hee, J. Murray +34 more
2024Nature Communications17 citations Open access
Semantic Scholar
Functionalized Carbon Nanostructures Versus Drug Resistance: Promising Scenarios in Cancer Treatment
M. Curcio, Annafranca Farfalla, F. Saletta, E. Valli +5 more
2020Molecules17 citations Open access
Semantic Scholar
N-Myc regulates expression of the detoxifying enzyme glutathione transferase GSTP1, a marker of poor outcome in neuroblastoma.
J. Fletcher, S. Gherardi, J. Murray, C. Burkhart +10 more
2012Cancer Research17 citations Open access
Semantic Scholar
The absence of dystrophin brain isoform expression in healthy human heart ventricles explains the pathogenesis of 5' X-linked dilated cardiomyopathy
M. Neri, E. Valli, G. Alfano, M. Bovolenta +7 more
2012BMC Medical Genetics17 citations Open access
Semantic Scholar
Combining antioxidant hydrogels with self-assembled microparticles for multifunctional wound dressings
M. Di Luca, M. Curcio, E. Valli, G. Cirillo +9 more
2019Journal of materials chemistry. B16 citations
Semantic Scholar
ABCC4/MRP4 contributes to the aggressiveness of Myc‐associated epithelial ovarian cancer
MoonSun Jung, Ji-Xuan Gao, L. Cheung, A. Bongers +17 more
2020International Journal of Cancer15 citations Open access
Semantic Scholar
The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis
J. Murray, E. Valli, G. Milazzo, C. Mayoh +34 more
2024Nature Communications14 citations Open access
Semantic Scholar
Molecular and Cellular Pathobiology A SP 1 / MIZ 1 / MYCN Repression Complex Recruits HDAC 1 at the TRKA and p 75 NTR Promoters and Affects Neuroblastoma Malignancy by Inhibiting the Cell Response to NGF
Nunzio Iraci, Daniel Diolaiti, Antonella Papa, Antonio Porro +7 more
20119 citations
Semantic Scholar
Suppression of Bcr-Abl Expression in CML by A Panel of miRNAs.
N. Iraci, E. Valli, S. Gherardi, S. Soverini +4 more
20098 citations
Semantic Scholar
A G316A Polymorphism in the Ornithine Decarboxylase Gene Promoter Modulates MYCN-Driven Childhood Neuroblastoma
Laura D. Gamble, Stefania Purgato, M. Henderson, S. Di Giacomo +31 more
2021Cancers7 citations Open access
Semantic Scholar
Targeting Functional Activity of AKT Has Efficacy against Aggressive Neuroblastoma.
M. Le Grand, Kathleen Kimpton, Christine C. Gana, E. Valli +2 more
2020ACS Pharmacology & Translational Science6 citations Open access
Semantic Scholar
Copper chelation inhibits TGF-β pathways and suppresses epithelial-mesenchymal transition in cancer
E. Poursani, D. Mercatelli, P. Raninga, J. Bell +20 more
2022bioRxiv2 citations Open access
Semantic Scholar
Expression Profiling of ABC Transporter Genes in Chronic Myeloid Leukemia (CML) and Responsiveness to Imatinib
N. Iraci, S. Soverini, S. Gherardi, E. Valli +15 more
20081 citations
Semantic Scholar
24 (PB012): Runx1t1 is an epigenetic regulator essential for MYCN-driven neuroblastoma tumorigenesis
M. Norris, J. Murray, E. Valli, G. Milazzo +12 more
2024European Journal of Cancer0 citations
Semantic Scholar
Withdrawal: The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for Down syndrome.
S. Trazzi, C. Fuchs, E. Valli, G. Perini +2 more
2020Journal of Biological Chemistry0 citations Open access
Semantic Scholar
Abstract 2616: A novel iron-chelating agent reduces MYC transcription via E2F gene family regulation
E. Valli, Cheng-Yuan Xue, L. Cheung, Laura D. Gamble +14 more
2019Molecular and Cellular Biology / Genetics0 citations
Semantic Scholar
Abstract 3435: Targeting AKT activity inhibits MYCN and sensitizes neuroblastoma to chemotherapeutic agents
M. Le Grand, Kathleen Kimpton, Christine C. Gana, E. Valli +2 more
2019Molecular and Cellular Biology / Genetics0 citations
Semantic Scholar
The ornithine decarboxylase G316A promoter polymorphism impacts neuroblastoma clinical outcome and may identify patients particularly susceptible to polyamine inhibition
Laura D. Gamble, Stefania Purgato, S. Di Giacomo, Amanda J. Russell +16 more
20180 citations
Semantic Scholar
Abstract 789: GSTP1 expression is regulated by MycN and is a marker of poor outcome in childhood neuroblastoma
M. Norris, J. Fletcher, S. Gherardi, J. Murray +9 more
20120 citations
Semantic Scholar
IKZF1 deletion patterns in adult ALL patients.
I. Iacobucci, N. Iraci, M. Messina, A. Lonetti +18 more
20120 citations Open access
Semantic Scholar
The role of MYCN-mediated transcriptional repression in neuronal physiopathology
E. Valli
20120 citations
Semantic Scholar
Cancer Genes and Genomics c-MYC Oncoprotein Dictates Transcriptional Profiles of ATP-Binding Cassette Transporter Genes in Chronic Myelogenous Leukemia CD 34 þ Hematopoietic Progenitor Cells
Antonio Porro, N. Iraci, S. Soverini, Daniel Diolaiti +12 more
20110 citations
Semantic Scholar
[P2.48]: Inverse relationship between CDKL5 and MYCN expression in neuroblastoma cell lines during differentiation
S. Trazzi, E. Valli, C. Fuchs, R. Bartesaghi +2 more
20100 citations
Semantic Scholar
P4.01 ncRNAs originating from the dystrophin gene as biomarker for assessing antisense therapy
M. Bovolenta, A. Armaroli, M. Neri, S. Brioschi +8 more
20100 citations
Semantic Scholar
C-Myc Mediated Regulation of Multidrug Resistance Genes in Chronic Myeloid Leukaemia Cd34+ Cell Progenitors.
S. Gherardi, S. Soverini, N. Iraci, C. Terragna +10 more
20090 citations
Semantic Scholar

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