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C. Bouquet · SciRah

Researcher profile · Semantic Scholar

C. Bouquet

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C. Bouquet — researcher profile on SciRah

h-index: 25
Works: 68
Citations: 1,703

Most-cited papers

Short‐Term BMP‐2 Expression Is Sufficient for In Vivo Osteochondral Differentiation of Mesenchymal Stem Cells
D. Noël, D. Gazit, C. Bouquet, F. Apparailly +7 more
2004Stem Cells245 citations
Semantic Scholar
Microtubule-Associated Protein 1B Controls Directionality of Growth Cone Migration and Axonal Branching in Regeneration of Adult Dorsal Root Ganglia Neurons
C. Bouquet, S. Soares, Y. von Boxberg, M. Ravaille-Veron +2 more
2004Journal of Neuroscience143 citations Open access
Semantic Scholar
Safety of rAAV2/2-ND4 Gene Therapy for Leber Hereditary Optic Neuropathy.
C. Vignal, S. Uretsky, S. Fitoussi, A. Galy +11 more
2018Ophthalmology (Rochester, Minn.)97 citations Open access
Semantic Scholar
Immune Response and Intraocular Inflammation in Patients With Leber Hereditary Optic Neuropathy Treated With Intravitreal Injection of Recombinant Adeno-Associated Virus 2 Carrying the ND4 Gene: A Secondary Analysis of a Phase 1/2 Clinical Trial
C. Bouquet, Catherine Vignal Clermont, A. Galy, S. Fitoussi +7 more
2019JAMA ophthalmology89 citations Open access
Semantic Scholar
Comparison of Different Bioreactor Systems for the Production of High Titer Retroviral Vectors
O. Merten, Pedro E. Cruz, C. Rochette, C. Gény-Fiamma +4 more
2001Biotechnology progress (Print)81 citations
Semantic Scholar
Efficient intracerebral delivery of AAV5 vector encoding human ARSA in non-human primate.
Marie-Anne Colle, F. Piguet, L. Bertrand, S. Raoul +9 more
2010Human Molecular Genetics74 citations
Semantic Scholar
Gene Electrotransfer of Plasmid Antiangiogenic Metargidin Peptide (AMEP) in Disseminated Melanoma: Safety and Efficacy Results of a Phase I First-in-Man Study
Iben Spanggaard, M. Snoj, A. Cavalcanti, C. Bouquet +8 more
2013Human Gene Therapy Clinical Development70 citations
Semantic Scholar
High tumoral levels of Kiss1 and G-protein-coupled receptor 54 expression are correlated with poor prognosis of estrogen receptor-positive breast tumors.
D. Marot, I. Bièche, Chantal Aumas, S. Esselin +7 more
2007Endocrine-Related Cancer67 citations Open access
Semantic Scholar
Canstatin acts on endothelial and tumor cells via mitochondrial damage initiated through interaction with alphavbeta3 and alphavbeta5 integrins.
C. Magnon, A. Galaup, B. Mullan, V. Rouffiac +5 more
2005Cancer Research65 citations
Semantic Scholar
MAP1B coordinates microtubule and actin filament remodeling in adult mouse Schwann cell tips and DRG neuron growth cones.
C. Bouquet, M. Ravaille-Veron, F. Propst, F. Nothias
2007Molecular and cellular neurosciences53 citations
Semantic Scholar
Suppression of angiogenesis, tumor growth, and metastasis by adenovirus-mediated gene transfer of human angiotensinogen.
C. Bouquet, N. Lamandé, Marcus Brand, J. Gasc +7 more
2006Molecular Therapy51 citations Open access
Semantic Scholar
Molecular mechanisms of axonal growth.
C. Bouquet, F. Nothias
2007Advances in Experimental Medicine and Biology46 citations
Semantic Scholar
Breast cancer, early stage
Tony S. K. Mok, L. Paz-Ares, Y.-L. Wu, S. Novello +496 more
201245 citations Open access
Semantic Scholar
Adenovirus-mediated transfer of wild-type p53 gene sensitizes TNF resistant MCF7 derivatives to the cytotoxic effect of this cytokine: relationship with c-myc and Rb
M. Ameyar, V. Shatrov, C. Bouquet, C. Capoulade +5 more
1999Oncogene45 citations Open access
Semantic Scholar
In vivo adenovirus-mediated delivery of a uPA/uPAR antagonist reduces retinal neovascularization in a mouse model of retinopathy
L. Legat, K. Gogat, C. Bouquet, M. Saint-Geniez +7 more
2003Gene Therapy43 citations Open access
Semantic Scholar
Halting angiogenesis by non-viral somatic gene therapy alleviates psoriasis and murine psoriasiform skin lesions.
J. Zibert, K. Wallbrecht, M. Schön, L. Mir +7 more
2011Journal of Clinical Investigation39 citations Open access
Semantic Scholar
Antitumoral Activity and Osteogenic Potential of Mesenchymal Stem Cells Expressing the Urokinase‐Type Plasminogen Antagonist Amino‐Terminal Fragment in a Murine Model of Osteolytic Tumor
V. Fritz, D. Noël, C. Bouquet, P. Opolon +10 more
2008Stem Cells38 citations
Semantic Scholar
Combined effects of docetaxel and angiostatin gene therapy in prostate tumor model.
A. Galaup, P. Opolon, C. Bouquet, Hong Li +5 more
2003Molecular Therapy37 citations Open access
Semantic Scholar
Neuronal and glial expression of the adhesion molecule TAG‐1 is regulated after peripheral nerve lesion or central neurodegeneration of adult nervous system
S. Soares, M. Traka, Y. von Boxberg, C. Bouquet +2 more
2005European Journal of Neuroscience34 citations
Semantic Scholar
Adenovirus-mediated gene transfer of urokinase plasminogen inhibitor inhibits angiogenesis in experimental arthritis
F. Apparailly, C. Bouquet, V. Millet, D. Noël +6 more
2002Gene Therapy32 citations
Semantic Scholar
Validation of a New Method for Quantifying In Vivo Murine Tumor Necrosis by Sonography
V. Rouffiac, C. Bouquet, N. Lassau, P. Opolon +4 more
2004Investigative Radiology31 citations
Semantic Scholar
Coelectrotransfer to skeletal muscle of three plasmids coding for antiangiogenic factors and regulatory factors of the tetracycline-inducible system: tightly regulated expression, inhibition of transplanted tumor growth, and antimetastatic effect.
D. Martel-Renoir, V. Trochon-Joseph, A. Galaup, C. Bouquet +6 more
2003Molecular Therapy29 citations Open access
Semantic Scholar
Adenovirus‐mediated wild‐type‐p53‐gene expression sensitizes TNF‐resistant tumor cells to TNF‐induced cytotoxicity by altering the cellular redox state
V. A. Shatrov, M. Ameyar, C. Bouquet, Z. Cai +3 more
2000International Journal of Cancer29 citations Open access
Semantic Scholar
Gene electrotransfer of plasmid AMEP, an integrin-targeted therapy, has antitumor and antiangiogenic action in murine B16 melanoma
M. Bošnjak, Tanja Dolinšek, M. Čemažar, S. Kranjc +9 more
2015Gene Therapy27 citations Open access
Semantic Scholar
Antitumoral and antimetastatic effect of antiangiogenic plasmids in B16 melanoma: Higher efficiency of the recombinant disintegrin domain of ADAM 15.
Liévin Daugimont, G. Vandermeulen, F. Defresne, C. Bouzin +4 more
2011European journal of pharmaceutics and biopharmaceutics27 citations
Semantic Scholar
Reduction of brain metastases in plasminogen activator inhibitor-1-deficient mice with transgenic ocular tumors.
Catherine Maillard, C. Bouquet, M. Petitjean, M. Mestdagt +9 more
2008Carcinogenesis25 citations Open access
Semantic Scholar
Systemic administration of a recombinant adenovirus encoding a HSA-Angiostatin kringle 1-3 conjugate inhibits MDA-MB-231 tumor growth and metastasis in a transgenic model of spontaneous eye cancer.
C. Bouquet, E. Frau, P. Opolon, E. Connault +4 more
2003Molecular Therapy21 citations Open access
Semantic Scholar
Efficient delivery of angiostatin K1-5 into tumors following insertion of an NGR peptide into adenovirus capsid
B. Jullienne, F. Vigant, E. Muth, R. Chaligné +4 more
2009Gene Therapy19 citations
Semantic Scholar
Biological Properties of Melanoma and Endothelial Cells after Plasmid AMEP Gene Electrotransfer Depend on Integrin Quantity on Cells
M. Bošnjak, L. Prosen, Tanja Dolinšek, Tanja Blagus +4 more
2013Journal of Membrane Biology16 citations
Semantic Scholar
Gene therapy for patients with advanced solid tumors: a phase I study using gene electrotransfer to muscle with the integrin inhibitor plasmid AMEP
Iben Spanggaard, Karin Dahlstroem, Line Laessoee, R. H. Hansen +5 more
2017Acta oncologica14 citations Open access
Semantic Scholar
Potentiation of radiotherapy by a localized antiangiogenic gene therapy.
N. Crokart, F. Danhier, Liévin Daugimont, Nélio Gonçalves +6 more
2013Radiotherapy and Oncology13 citations
Semantic Scholar
A gene transfer comparative study of HSA-conjugated antiangiogenic factors in a transgenic mouse model of metastatic ocular cancer
E. Frau, C. Magnon, P. Opolon, E. Connault +5 more
2007Cancer Gene Therapy13 citations Open access
Semantic Scholar
High level of stabilized angiostatin mediated by adenovirus delivery does not impair the growth of human neuroblastoma xenografts
J. Joseph, C. Bouquet, P. Opolon, J. Morizet +6 more
2003Cancer Gene Therapy13 citations Open access
Semantic Scholar
268. Optogenetic Engineering of Retinal Ganglion Cells with AAV2.7m8-ChrimsonR-tdTomato (GS030-DP) Is Well Tolerated and Induces Functional Responses to Light in Non-Human Primates
A. Douar, C. Bouquet, D. Pruneau, J. Chavas +7 more
20168 citations Open access
Semantic Scholar
Proof of Concept of Gene Therapy Using Plasmid Amep in Disseminated Melanoma: Safety and Efficacy Results of A Phase I First-In-Man Study
Iben Spanggaard, M. Snoj, A. Cavalcanti, C. Bouquet +6 more
20125 citations Open access
Semantic Scholar
Recombinant interleukin-2 pre-treatment increases anti-tumor response to paclitaxel by affecting lung P-glycoprotein expression on the Lewis lung carcinoma
B. Hosten, Désiré Challuau, S. Gil, C. Bouquet +5 more
2006Anti-Cancer Drugs5 citations
Semantic Scholar
Interferon-alpha improves docetaxel antitumoral and antimetastatic efficiency in Lewis lung carcinoma bearing mice.
Makrem Ben Reguiga, C. Bouquet, R. Farinotti, L. Bonhomme‐Faivre
2012Life Science4 citations
Semantic Scholar
Intravitreal rAAV2/2-ND4 (GS010): A gene therapy for vision loss in Leber’s Hereditary Optic Neuropathy (LHON) caused by the G11778A ND4 mitochondrial mutation (S26.005)
S. Uretsky, C. Vignal, N. Thomasson, C. Bouquet +4 more
2017Neurology3 citations
Semantic Scholar
VTX-PID as a novel recombinant immunoglobulin G–degrading enzyme (IdeS) for efficient AAV-based gene therapy in participants with neutralizing antibodies: results of the phase I first-in-human NAVIgATE study
B. Bénichou, Rainard Fuhr, Elodie Vernadal, Sonia Valero +10 more
2026Frontiers in Immunology1 citations Open access
Semantic Scholar
Impact of sequential bilateral intravitreal injection of rAAV2/2-ND4 on ocular and systemic humoral immune status in non-human primates
C. Bouquet, A. Galy, Catherine Cancian, N. Thomasson
20181 citations
Semantic Scholar
Phase I/IIa Visual Acuity Outcomes 1.5-Years Post-Treatment with rAAV2/2-ND4, an Investigational Gene Therapy for ND4 LHON
S. Uretsky, N. Thomasson, C. Bouquet, A. Galy +4 more
20171 citations
Semantic Scholar
267. Phase I Gene Therapy Preliminary Clinical Results for Treatment of ND4 Leber Hereditary Optic Neuropathy with rAAV2-2-ND4
S. Uretsky, C. Vignal, S. Bidot, S. Fitoussi +7 more
20161 citations Open access
Semantic Scholar
Optogenetic engineering of retinal ganglion cells with AAV2.7m8-ChrimsonR-tdTomato (GS030) in combination with an event-based camera photostimulation device
J. Sahel, D. Dalkara, Jens Duebel, R. Benosman +7 more
20161 citations
Semantic Scholar
P05.4 Brain gene therapy for Metachromatic Leukodystrophy: from bench to bedside
C. Sevin, T. Roujeau, F. Piguet, D. Sondhi +12 more
20111 citations
Semantic Scholar
Antitumoral Activity and Osteogenic Potential of hATF-Expressing Mesenchymal Stem Cells In A Murine Model of Osteolytic Tumor.
V. Fritz, D. Noël, C. Bouquet, P. Opolon +10 more
20081 citations
Semantic Scholar
A gene transfer comparative study of HSA-conjugated antiangiogenic factors in a transgenic mouse model of metastatic ocular cancer
E. Frau, C. Magnon, P. Opolon, E. Connault +5 more
2007Cancer Gene Therapy1 citations Open access
Semantic Scholar
967. Angiotensinogen Inhibits Growth and Angiogenesis of Human Mammary Carcinoma and Prevents Pulmonary Metastasis of Murine Melanoma Cancer
C. Bouquet, N. Lamandé, J. Gasc, F. Griscelli +4 more
20041 citations Open access
Semantic Scholar
Prevalence of adeno-associated virus type 3B neutralizing antibodies in cohorts of healthy donors and Wilson's disease adults.
C. Bouquet, Blanche Tamarit, G. G. Aseguinolaza, Veronica Ferrer +5 more
2026Gene Therapy0 citations Open access
Semantic Scholar
Correction: VTX-PID as a novel recombinant immunoglobulin G–degrading enzyme (IdeS) for efficient AAV-based gene therapy in participants with neutralizing antibodies: results of the phase I first-in-human NAVIgATE study
B. Bénichou, Rainard Fuhr, Elodie Vernadal, Sonia Valero +10 more
2026Frontiers in Immunology0 citations Open access
Semantic Scholar
Liver-directed gene therapy results in amelioration of progressive familial intrahepatic cholestasis type 2 in mice
Angie Molina, L. Trigueros-Motos, Manuela Molina, Javier Martínez-García +11 more
2026Hepatology Communications0 citations Open access
Semantic Scholar

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