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O. Merten · SciRah

Researcher profile · Semantic Scholar

O. Merten

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O. Merten — researcher profile on SciRah

h-index: 31
Works: 106
Citations: 3,524

Most-cited papers

Guidance on Good Cell Culture Practice
S. Coecke, M. Balls, G. Bowe, John M. Davis +8 more
2005Alternatives to laboratory animals : ATLA395 citations Open access
Semantic Scholar
Growth factor delivery approaches in hydrogels.
Amanda K. Andriola Silva, C. Richard, M. Bessodes, D. Scherman +1 more
2009Biomacromolecules263 citations
Semantic Scholar
Large-Scale Manufacture and Characterization of a Lentiviral Vector Produced for Clinical Ex Vivo Gene Therapy Application
O. Merten, S. Charrier, Nicolas Laroudie, S. Fauchille +10 more
2011Human Gene Therapy192 citations
Semantic Scholar
Production of lentiviral vectors
O. Merten, Matthias Hebben, C. Bovolenta
2016Molecular Therapy: Methods & Clinical Development172 citations Open access
Semantic Scholar
Advances in cell culture: anchorage dependence
O. Merten
2015Philosophical Transactions of the Royal Society B: Biological Sciences143 citations Open access
Semantic Scholar
Virus contaminations of cell cultures – A biotechnological view
O. Merten
2002Cytotechnology (Dordrecht)125 citations Open access
Semantic Scholar
Cell microcarriers and microcapsules of stimuli-responsive polymers.
A. A. S. Brun-Graeppi, C. Richard, M. Bessodes, D. Scherman +1 more
2011Journal of Controlled Release117 citations
Semantic Scholar
Thermoresponsive surfaces for cell culture and enzyme-free cell detachment
A. A. S. Brun-Graeppi, C. Richard, M. Bessodes, D. Scherman +1 more
2010115 citations
Semantic Scholar
State‐of‐the‐art of the production of retroviral vectors
O. Merten
2004Journal of Gene Medicine110 citations
Semantic Scholar
Current issues in adeno-associated viral vector production
O. Merten, C. Gény-Fiamma, AM Douar
2005Gene Therapy95 citations Open access
Semantic Scholar
Advanced Characterization of DNA Molecules in rAAV Vector Preparations by Single-stranded Virus Next-generation Sequencing
Emilie Lecomte, Benoît Tournaire, Benjamin Cogné, J. Dupont +11 more
2015Molecular Therapy: Nucleic Acids83 citations Open access
Semantic Scholar
Study on the sol-gel transition of xyloglucan hydrogels
A. A. S. Brun-Graeppi, C. Richard, M. Bessodes, D. Scherman +3 more
201082 citations
Semantic Scholar
Comparison of Different Bioreactor Systems for the Production of High Titer Retroviral Vectors
O. Merten, Pedro E. Cruz, C. Rochette, C. Gény-Fiamma +4 more
2001Biotechnology progress (Print)81 citations
Semantic Scholar
Capsid-specific removal of circulating antibodies to adeno-associated virus vectors
B. Bertin, Philippe Véron, C. Leborgne, J. Deschamps +14 more
2020Scientific Reports79 citations Open access
Semantic Scholar
Introduction to animal cell culture technology—past, present and future
O. Merten
2006Cytotechnology (Dordrecht)72 citations Open access
Semantic Scholar
Engineering of baculovirus vectors for the manufacture of virion‐free biopharmaceuticals
M. Marek, M. V. van Oers, Feana Francis Devaraj, J. Vlak +1 more
2011Biotechnology and Bioengineering67 citations Open access
Semantic Scholar
Production of influenza virus in cell cultures for vaccine preparation.
O. Merten, C. Hannoun, J. Manuguerra, F. Ventre +1 more
1996Advances in Experimental Medicine and Biology65 citations
Semantic Scholar
Latest developments in the large-scale production of adeno-associated virus vectors in insect cells toward the treatment of neuromuscular diseases.
L. Galibert, O. Merten
2011Journal of Invertebrate Pathology64 citations
Semantic Scholar
Baculovirus VP80 Protein and the F-Actin Cytoskeleton Interact and Connect the Viral Replication Factory with the Nuclear Periphery
M. Marek, O. Merten, L. Galibert, J. Vlak +1 more
2011Journal of Virology63 citations Open access
Semantic Scholar
How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology?
M. Carrondo, P. Alves, Nuno Carinhas, J. Glassey +10 more
2012Biotechnology Journal56 citations Open access
Semantic Scholar
AAV vector production: state of the art developments and remaining challenges
O. Merten
201642 citations
Semantic Scholar
Evaluation of the new serum-free medium (MDSS2) for the production of different biologicals: Use of various cell lines
O. Merten, J. Kierulff, N. Castignolles, P. Perrin
2004Cytotechnology (Dordrecht)39 citations
Semantic Scholar
Viral vectors for gene therapy and gene modification approaches
O. Merten, Bruno Gaillet
201638 citations
Semantic Scholar
Manufacturing of viral vectors for gene therapy: part I. Upstream processing
O. Merten, M. Schweizer, P. Chahal, A. Kamen
201437 citations Open access
Semantic Scholar
Manufacturing of viral vectors: part II. Downstream processing and safety aspects
O. Merten, M. Schweizer, P. Chahal, A. Kamen
201434 citations Open access
Semantic Scholar
Development of serum-free media for cell growth and production of viruses/viral vaccines--safety issues of animal products used in serum-free media.
O. Merten
2002Developments in Biologicals34 citations
Semantic Scholar
Cell Culture Processes for the Production of Viral Vectors for Gene Therapy Purposes
J. Warnock, O. Merten, M. Al-Rubeai
2006Cytotechnology (Dordrecht)33 citations Open access
Semantic Scholar
Adeno-associated viruses.
M. Mezzina, O. Merten
2011Methods in molecular biology32 citations
Semantic Scholar
Quantitative proteomic analysis of lentiviral vectors using 2‐DE
J. Denard, S. Rundwasser, Nicolas Laroudie, Florence Gonnet +6 more
2009Proteomics32 citations Open access
Semantic Scholar
Effect of medium sugar source on the production of retroviral vectors for gene therapy
A. S. Coroadinha, J. Ribeiro, A. Roldão, P. Cruz +3 more
2006Biotechnology and Bioengineering32 citations
Semantic Scholar
New Developments and New Applications in Animal Cell Technology
O. Merten, P. Perrin, B. Griffiths
2002Springer Netherlands30 citations
Semantic Scholar
Kinetic analysis of hybridoma growth and monoclonal antibody production in semicontinuous culture
M. Leno, O. Merten, J. Hache
1992Biotechnology and Bioengineering30 citations
Semantic Scholar
Impact of Inverted Terminal Repeat Integrity on rAAV8 Production Using the Baculovirus/Sf9 Cells System
Adrien Savy, Yohann Dickx, Lucile Nauwynck, D. Bonnin +2 more
2017Human Gene Therapy Methods28 citations Open access
Semantic Scholar
The effect of sterilization methods on the thermo-gelation properties of xyloglucan hydrogels
A. A. S. Brun-Graeppi, C. Richard, M. Bessodes, D. Scherman +3 more
201027 citations
Semantic Scholar
Batch production and growth kinetics of hybridomas
O. Merten
1988Cytotechnology (Dordrecht)26 citations
Semantic Scholar
Toward a Scalable Purification Protocol of GaLV-TR-Pseudotyped Lentiviral Vectors
Driss Boudeffa, B. Bertin, A. Biek, M. Mormin +3 more
2019Human Gene Therapy Methods23 citations
Semantic Scholar
Origins of truncated supplementary capsid proteins in rAAV8 vectors produced with the baculovirus system
L. Galibert, Adrien Savy, Yohann Dickx, D. Bonnin +4 more
2018PLoS ONE23 citations Open access
Semantic Scholar
Influence of Mildly Acidic pH Conditions on the Production of Lentiviral and Retroviral Vectors
N. Holic, A. Seye, S. Majdoul, S. Martin +3 more
2014Human Gene Therapy Clinical Development23 citations Open access
Semantic Scholar
Host cells and cell banking.
G. Stacey, O. Merten
2011Methods in molecular biology21 citations
Semantic Scholar
Monobac System–A Single Baculovirus for the Production of rAAV
L. Galibert, Aurélien Jacob, Adrien Savy, Yohann Dickx +7 more
2021Microorganisms20 citations Open access
Semantic Scholar
On-Line Detection of Microbial Contaminations in Animal Cell Reactor Cultures Using an Electronic Nose Device
K. Kreij, C. Mandenius, J. Clemente, A. Cunha +14 more
2005Cytotechnology (Dordrecht)20 citations Open access
Semantic Scholar
Impact of Retroviral Vector Components Stoichiometry on Packaging Cell Lines: Effects on Productivity and Vector Quality
M. Carrondo, O. Merten, M. Haury, P. Alves +1 more
2008Human Gene Therapy18 citations
Semantic Scholar
Evaluation of the serum-free medium MDSS2 for the production of poliovirus on vero cells in bioreactors
O. Merten, R. Wu, E. Couvé, R. Crainic
1997Cytotechnology (Dordrecht)17 citations Open access
Semantic Scholar
Baculovirus VP1054 Is an Acquired Cellular PURα, a Nucleic Acid-Binding Protein Specific for GGN Repeats
M. Marek, C. Romier, L. Galibert, O. Merten +1 more
2013Journal of Virology16 citations Open access
Semantic Scholar
Growth Factor Delivery Approaches in Hydrogels Biomacromolecules
Amanda K. Andriola Silva, C. Richard, M. Bessodes, D. Scherman +1 more
200816 citations
Semantic Scholar
Concentrating mammalian cells I. large-scale animal cell culture
O. Merten
198715 citations
Semantic Scholar
Xyloglucan-derivatized films for the culture of adherent cells and their thermocontrolled detachment: a promising alternative to cells sensitive to protease treatment.
A. Silva, C. Richard, G. Ducouret, M. Bessodes +2 more
2013Biomacromolecules14 citations
Semantic Scholar
Modified monoclonal antibody production kinetics kappa/gamma mRNA levels, and metabolic activities in a murine hybridoma selected by continuous Culture
O. Merten, D. Moeurs, H. Keller, M. Leno +3 more
1994Biotechnology and Bioengineering13 citations
Semantic Scholar
A new method for the encapsulation of mammalian cells
O. Merten, H. Dautzenberg, G. Pálfi
1991Cytotechnology (Dordrecht)13 citations
Semantic Scholar
Use of a dynamic filtration method for separation of animal cells.
E. Rebsamen, W. Goldinger, W. Scheirer, O. Merten +1 more
1987Developments in biological standardization12 citations
Semantic Scholar

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