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D. Dalkara · SciRah

Researcher profile · Semantic Scholar

D. Dalkara

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D. Dalkara — researcher profile on SciRah

h-index: 49
Works: 172
Citations: 7,799

Most-cited papers

Partial recovery of visual function in a blind patient after optogenetic therapy
J. Sahel, Élise Boulanger-Scemama, C. Pagot, A. Arleo +14 more
2021Nature Medicine585 citations
Semantic Scholar
Early and late stage gene therapy interventions for inherited retinal degenerations.
C. Botto, Marco Rucli, M. Tekinsoy, J. Pulman +2 more
2021Progress in retinal and eye research161 citations Open access
Semantic Scholar
Red‐shifted channelrhodopsin stimulation restores light responses in blind mice, macaque retina, and human retina
Abhishek Sengupta, A. Chaffiol, E. Macé, R. Caplette +9 more
2016EMBO Molecular Medicine147 citations Open access
Semantic Scholar
A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque Retina.
A. Chaffiol, R. Caplette, C. Jaillard, E. Brazhnikova +13 more
2017Molecular Therapy132 citations Open access
Semantic Scholar
Let There Be Light: Gene and Cell Therapy for Blindness
D. Dalkara, O. Goureau, K. Marazova, J. Sahel
2016Human Gene Therapy128 citations Open access
Semantic Scholar
Neural circuits in the mouse retina support color vision in the upper visual field
Klaudia P. Szatko, Maria M. Korympidou, Yan-Li Ran, Philipp Berens +4 more
2019bioRxiv121 citations Open access
Semantic Scholar
Nicotine inhibits the VTA-to-amygdala dopamine pathway to promote anxiety.
C. Nguyen, S. Mondoloni, T. Le Borgne, I. Centeno +18 more
2021Neuron120 citations Open access
Semantic Scholar
Noninvasive gene delivery to foveal cones for vision restoration.
Hanen Khabou, Marcela Garita-Hernandez, A. Chaffiol, S. Reichman +11 more
2018JCI Insight108 citations Open access
Semantic Scholar
Restoration of visual function by transplantation of optogenetically engineered photoreceptors
Marcela Garita-Hernandez, M. Lampič, A. Chaffiol, L. Guibbal +12 more
2018Nature Communications102 citations Open access
Semantic Scholar
The primate model for understanding and restoring vision
S. Picaud, D. Dalkara, K. Marazova, O. Goureau +2 more
2019Proceedings of the National Academy of Sciences of the United States of America101 citations Open access
Semantic Scholar
Optogenetic therapy: high spatiotemporal resolution and pattern discrimination compatible with vision restoration in non-human primates
G. Gauvain, H. Akolkar, A. Chaffiol, F. Arcizet +20 more
2021Communications Biology95 citations Open access
Semantic Scholar
Linking YAP to Müller glia quiescence exit in the degenerative retina
Annaïg Hamon, Diana García-García, Divya Ail, J. Bitard +5 more
2018bioRxiv95 citations Open access
Semantic Scholar
Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium
Debra A. Thompson, A. Iannaccone, R. Ali, Vadim Y. Arshavsky +31 more
2020Translational Vision Science & Technology89 citations Open access
Semantic Scholar
Dosage Thresholds and Influence of Transgene Cassette in Adeno-Associated Virus–Related Toxicity
Hanen Khabou, Chloé Cordeau, Laurence Pacot, S. Fisson +1 more
2018Human Gene Therapy77 citations
Semantic Scholar
Ectopic expression of a mechanosensitive channel confers spatiotemporal resolution to ultrasound stimulations of neurons for visual restoration
Sara Cadoni, C. Demené, I. Alcala, M. Provansal +16 more
2023Nature Nanotechnology75 citations Open access
Semantic Scholar
Insight into the mechanisms of enhanced retinal transduction by the engineered AAV2 capsid variant ‐7m8
Hanen Khabou, M. Desrosiers, C. Winckler, Stéphane Fouquet +4 more
2016Biotechnology and Bioengineering71 citations Open access
Semantic Scholar
AAV-Mediated Gene Delivery to 3D Retinal Organoids Derived from Human Induced Pluripotent Stem Cells
Marcela Garita-Hernandez, Fiona Routet, L. Guibbal, Hanen Khabou +7 more
2020International Journal of Molecular Sciences70 citations Open access
Semantic Scholar
In Vivo Submillisecond Two-Photon Optogenetics with Temporally Focused Patterned Light
I-Wen Chen, E. Ronzitti, Brian R. Lee, T. Daigle +4 more
2019Journal of Neuroscience66 citations Open access
Semantic Scholar
Melanopsin Variants as Intrinsic Optogenetic On and Off Switches for Transient versus Sustained Activation of G Protein Pathways.
Katharina Spoida, Dennis Eickelbeck, Raziye Karapinar, Tobias Eckhardt +7 more
2016Current Biology66 citations Open access
Semantic Scholar
Gene Therapy for Inherited Retinal Disease: Long-Term Durability of Effect
B. Leroy, M. D. Fischer, J. Flannery, R. MacLaren +6 more
2022Ophthalmic Research62 citations Open access
Semantic Scholar
In vivo–directed evolution of adeno-associated virus in the primate retina
L. Byrne, Timothy P. Day, Meike Visel, Jennifer A. Strazzeri +5 more
202062 citations
Semantic Scholar
Vectors and Gene Delivery to the Retina.
Arthur Planul, D. Dalkara
2017Annual Review of Vision Science59 citations
Semantic Scholar
Non-viral delivery of chemically modified mRNA to the retina: Subretinal versus intravitreal administration.
J. Devoldere, K. Peynshaert, H. Dewitte, C. Vanhove +6 more
2019Journal of Controlled Release52 citations
Semantic Scholar
Systemic and local immune responses to intraocular AAV vector administration in non-human primates
Divya Ail, Duohao Ren, E. Brazhnikova, Céline Nouvel-Jaillard +4 more
2022Molecular Therapy: Methods & Clinical Development49 citations Open access
Semantic Scholar
Optogenetic Light Sensors in Human Retinal Organoids
Marcela Garita-Hernandez, L. Guibbal, Lyes Toualbi, Fiona Routet +10 more
2018Frontiers in Neuroscience49 citations Open access
Semantic Scholar
Immune Responses to Gene Editing by Viral and Non-Viral Delivery Vectors Used in Retinal Gene Therapy
Duohao Ren, S. Fisson, D. Dalkara, Divya Ail
2022Pharmaceutics47 citations Open access
Semantic Scholar
The Thioredoxin Encoded by the Rod-Derived Cone Viability Factor Gene Protects Cone Photoreceptors Against Oxidative Stress
X. Mei, A. Chaffiol, Christo Kole, Ying Yang +8 more
2016Antioxidants and Redox Signaling46 citations Open access
Semantic Scholar
Chronic nicotine increases midbrain dopamine neuron activity and biases individual strategies towards reduced exploration in mice
Malou Dongelmans, Romain Durand-de Cuttoli, C. Nguyen, M. Côme +15 more
2021Nature Communications39 citations Open access
Semantic Scholar
Opsins for vision restoration.
Cardillia-Joe Simon, J. Sahel, Jens Duebel, S. Herlitze +1 more
2020Biochemical and Biophysical Research Communications - BBRC34 citations Open access
Semantic Scholar
Towards optogenetic vision restoration with high resolution
U. Ferrari, Stéphane Deny, Abhishek Sengupta, R. Caplette +6 more
2020PLoS Comput. Biol.34 citations Open access
Semantic Scholar
In vivo directed evolution of AAV in the primate retina
L. Byrne, Timothy P. Day, Meike Visel, Jennifer A. Strazzeri +5 more
2019bioRxiv34 citations Open access
Semantic Scholar
Loss of CRB2 in Müller glial cells modifies a CRB1‐associated retinitis pigmentosa phenotype into a Leber congenital amaurosis phenotype
Peter M. J. Quinn, A. Mulder, Henrique C. Alves, M. Desrosiers +6 more
2018Human Molecular Genetics31 citations Open access
Semantic Scholar
The temporal structure of the inner retina at a single glance
Zhi-Jian Zhao, David A. Klindt, André Maia Chagas, Klaudia P. Szatko +10 more
2019Scientific Reports28 citations Open access
Semantic Scholar
Adeno-Associated Virus (AAV) - Based Gene Therapies for Retinal Diseases: Where are We?
Divya Ail, H. Malki, Emilia A. Zin, D. Dalkara
2023The Application of Clinical Genetics27 citations Open access
Semantic Scholar
Progress in Gene Editing Tools and Their Potential for Correcting Mutations Underlying Hearing and Vision Loss
C. Botto, D. Dalkara, A. El-Amraoui
2021Frontiers in Genome Editing23 citations Open access
Semantic Scholar
AAV-mediated gene therapy in Dystrophin-Dp71 deficient mouse leads to blood-retinal barrier restoration and oedema reabsorption.
Ophélie Vacca, Hugo Charles-Messance, Brahim El Mathari, A. Séne +11 more
2016Human Molecular Genetics23 citations
Semantic Scholar
New Editing Tools for Gene Therapy in Inherited Retinal Dystrophies
J. Pulman, J. Sahel, D. Dalkara
2022The CRISPR Journal21 citations Open access
Semantic Scholar
All-optical inter-layers functional connectivity investigation in the mouse retina
G. Spampinato, E. Ronzitti, V. Zampini, U. Ferrari +8 more
2022Cell Reports Methods19 citations Open access
Semantic Scholar
Assessing Photoreceptor Status in Retinal Dystrophies: From High-Resolution Imaging to Functional Vision
J. Sahel, K. Grieve, C. Pagot, C. Authié +12 more
2021American journal of ophthalmology-glaucoma18 citations Open access
Semantic Scholar
Optogenetic therapy: High spatiotemporal resolution and pattern recognition compatible with vision restoration in non-human primates
G. Gauvain, H. Akolkar, A. Chaffiol, F. Arcizet +20 more
2020bioRxiv18 citations Open access
Semantic Scholar
Optogenetic targeting of AII amacrine cells restores retinal computations performed by the inner retina
Hanen Khabou, Elaine Orendorff, Francesco Trapani, Marco Rucli +4 more
2022bioRxiv17 citations Open access
Semantic Scholar
Restoration of mGluR6 Localization Following AAV-Mediated Delivery in a Mouse Model of Congenital Stationary Night Blindness
Juliette Varin, Nassima Bouzidi, M. M. de Sousa Dias, T. Pugliese +7 more
2021Investigative Ophthalmology and Visual Science17 citations Open access
Semantic Scholar
Functional ultrasound imaging of the spreading activity following optogenetic stimulation of the rat visual cortex
M. Provansal, G. Labernède, C. Joffrois, A. Rizkallah +11 more
2021Scientific Reports17 citations Open access
Semantic Scholar
Rescue of Defective Electroretinographic Responses in Dp71-Null Mice With AAV-Mediated Reexpression of Dp71
M. Barboni, C. Vaillend, Anneka Joachimsthaler, A. Liber +9 more
2020Investigative Ophthalmology and Visual Science17 citations Open access
Semantic Scholar
Control of Microbial Opsin Expression in Stem Cell Derived Cones for Improved Outcomes in Cell Therapy
Marcela Garita-Hernandez, A. Chaffiol, L. Guibbal, Fiona Routet +8 more
2021Frontiers in Cellular Neuroscience16 citations Open access
Semantic Scholar
Numb regulates Tau levels and prevents neurodegeneration in tauopathy mouse models
Marine Lacomme, Sarah C. Hales, Thomas W. Brown, Katarina Stevanovic +6 more
2022Science Advances15 citations Open access
Semantic Scholar
Substantial restoration of night vision in adult mice with congenital stationary night blindness
Juliette Varin, Nassima Bouzidi, G. Gauvain, C. Joffrois +11 more
2021Molecular Therapy: Methods & Clinical Development15 citations Open access
Semantic Scholar
Gene therapy for retinal dystrophy
J. Sahel, D. Dalkara
2019Nature Medicine14 citations
Semantic Scholar
Neutralizing Antibodies Against Adeno-Associated Virus (AAV): Measurement and Influence on Retinal Gene Delivery.
M. Desrosiers, D. Dalkara
2018Methods in molecular biology13 citations
Semantic Scholar
Sphingosine 1-Phosphate Receptor 1 Modulates CNTF-Induced Axonal Growth and Neuroprotection in the Mouse Visual System
S. Joly, D. Dalkara, V. Pernet
2017Journal of Neural Transplantation and Plasticity13 citations Open access
Semantic Scholar

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Hanen Khabou×8

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