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M. Jäättelä · SciRah

Researcher profile · Semantic Scholar

M. Jäättelä

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M. Jäättelä — researcher profile on SciRah

h-index: 95
Works: 268
Citations: 54K

Most-cited papers

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L. Galluzzi, I. Vitale, S. Aaronson, J. Abrams +165 more
2018Cell Death and Differentiation6,079 citations Open access
Semantic Scholar
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
D. Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, M. Abdellatif +496 more
2021Autophagy4,016 citations Open access
Semantic Scholar
Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652
D. Klionsky, K. Abdelmohsen, A. Abe, M. Abedin +496 more
20161,544 citations Open access
Semantic Scholar
Molecular definitions of autophagy and related processes
L. Galluzzi, E. Baehrecke, A. Ballabio, P. Boya +50 more
2017EMBO Journal1,480 citations Open access
Semantic Scholar
Autophagy in major human diseases
D. Klionsky, G. Petroni, R. Amaravadi, E. Baehrecke +55 more
2021EMBO Journal1,411 citations Open access
Semantic Scholar
Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay
S. Aits, J. Kricker, Bin Liu, Anne-Marie Ellegaard +9 more
2015Autophagy408 citations Open access
Semantic Scholar
Apoptotic cell death in disease—Current understanding of the NCCD 2023
I. Vitale, F. Pietrocola, E. Guilbaud, S. Aaronson +224 more
2023Cell Death and Differentiation346 citations Open access
Semantic Scholar
Heat Shock Protein-based therapy as a potential candidate for treating sphingolipidoses
T. Kirkegaard, James Gray, D. Priestman, Kerri-Lee Wallom +16 more
2016Science Translational Medicine162 citations Open access
Semantic Scholar
Cholesterol transfer via endoplasmic reticulum contacts mediates lysosome damage repair
Maja Radulovic, E. M. Wenzel, Sania Gilani, L. K. Holland +8 more
2022EMBO Journal149 citations Open access
Semantic Scholar
Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization
Sonia Hernández‐Tiedra, G. Fabriàs, D. Dávila, Iñigo J. Salanueva +22 more
2016Autophagy135 citations Open access
Semantic Scholar
Repurposing Cationic Amphiphilic Antihistamines for Cancer Treatment
Anne-Marie Ellegaard, C. Dehlendorff, A. Vind, A. Anand +8 more
2016EBioMedicine135 citations Open access
Semantic Scholar
Lysosomes in cancer- living on the edge (of the cell)
Saara Hämälistö, M. Jäättelä
2016Current Opinion in Cell Biology124 citations Open access
Semantic Scholar
How to Choose the Right Inducible Gene Expression System for Mammalian Studies?
T. Kallunki, M. Barišić, M. Jäättelä, Bin Liu
2019Cells112 citations Open access
Semantic Scholar
The ubiquitin‐conjugating enzyme UBE2QL1 coordinates lysophagy in response to endolysosomal damage
L. Koerver, C. Papadopoulos, Bin Liu, B. Kravić +10 more
2019EMBO Reports111 citations Open access
Semantic Scholar
Hsp70 interactions with membrane lipids regulate cellular functions in health and disease.
Z. Balogi, G. Multhoff, Thomas Kirkegaard Jensen, Emyr Lloyd-Evans +4 more
2019Progress in lipid research99 citations Open access
Semantic Scholar
STAT3 associates with vacuolar H+-ATPase and regulates cytosolic and lysosomal pH
Bin Liu, J. Palmfeldt, Lin Lin, A. Colaco +7 more
2018Cell Research97 citations Open access
Semantic Scholar
Annexin A7 is required for ESCRT III-mediated plasma membrane repair
S. L. Sønder, T. Boye, R. Tölle, J. Dengjel +5 more
2019Scientific Reports95 citations Open access
Semantic Scholar
Methods for the functional quantification of lysosomal membrane permeabilization: a hallmark of lysosomal cell death
S. Aits, M. Jäättelä, J. Nylandsted
2015Methods in Cell Biology87 citations Open access
Semantic Scholar
Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites
Søs Grønbæk Holdgaard, Valentina Cianfanelli, Emanuela Pupo, M. Lambrughi +24 more
2018Nature Communications80 citations Open access
Semantic Scholar
TFEB‐dependent lysosome biogenesis is required for senescence
Rachel Curnock, Katy Yalci, J. Palmfeldt, M. Jäättelä +2 more
2023EMBO Journal78 citations Open access
Semantic Scholar
Spatially and temporally defined lysosomal leakage facilitates mitotic chromosome segregation
Saara Hämälistö, J. L. Stahl, E. Favaro, Qing Yang +8 more
2020Nature Communications75 citations Open access
Semantic Scholar
CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation
P. Puustinen, A. Rytter, Monika Mortensen, P. Kohonen +2 more
2014Journal of Cell Biology75 citations Open access
Semantic Scholar
Autophagy role(s) in response to oncogenes and DNA replication stress
Riccardo Vanzo, J. Bártková, J. Merchut-Maya, Arnaldur Hall +7 more
2019Cell Death and Differentiation72 citations Open access
Semantic Scholar
Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure
Elisabeth Corcelle-Termeau, S. Vindeløv, Saara Hämälistö, B. Mograbi +12 more
2016Autophagy69 citations Open access
Semantic Scholar
Lysosome as a Central Hub for Rewiring PH Homeostasis in Tumors
Ran Chen, M. Jäättelä, Bin Liu
2020Cancers65 citations Open access
Semantic Scholar
SnapShot: Lysosomal Functions.
Lya K. K. Holland, I. Nielsen, K. Maeda, M. Jäättelä
2020Cell55 citations Open access
Semantic Scholar
Human heat shock protein 70 (Hsp70) as a peripheral membrane protein.
A. Mahalka, T. Kirkegaard, Laura T I Jukola, M. Jäättelä +1 more
2014Biochimica et Biophysica Acta54 citations Open access
Semantic Scholar
DNA-dependent protein kinase regulates lysosomal AMP-dependent protein kinase activation and autophagy
P. Puustinen, Anne Keldsbo, Elisabeth Corcelle-Termeau, K. Ngoei +5 more
2020Autophagy52 citations Open access
Semantic Scholar
Proton pump inhibitor use and cancer mortality
S. Tvingsholm, C. Dehlendorff, K. Østerlind, S. Friis +1 more
2018International Journal of Cancer52 citations Open access
Semantic Scholar
pH gradient reversal fuels cancer progression.
Tian-Yu Zheng, M. Jäättelä, Bin Liu
2020International Journal of Biochemistry and Cell Biology50 citations
Semantic Scholar
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356
D. Klionsky, K. Abdelmohsen, A. Abe, J. Abedin +496 more
201650 citations Open access
Semantic Scholar
Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination
A. Baude, T. L. Aaes, B. Zhai, Nader Al-Nakouzi +4 more
2015Nucleic Acids Research44 citations Open access
Semantic Scholar
The Mutational Landscape of the Oncogenic MZF1 SCAN Domain in Cancer
Mads Nygaard, Thilde Terkelsen, André Vidas Olsen, Valentina Sora +10 more
2016Frontiers in Molecular Biosciences38 citations Open access
Semantic Scholar
Targeting Cancer Lysosomes with Good Old Cationic Amphiphilic Drugs.
Anne-Marie Ellegaard, P. Bach, M. Jäättelä
2021Reviews of Physiology, Biochemistry and Pharmacology37 citations
Semantic Scholar
Control of mitosis, inflammation, and cell motility by limited leakage of lysosomes.
Jonathan Stahl-Meyer, Kamilla Stahl-Meyer, M. Jäättelä
2021Current Opinion in Cell Biology34 citations Open access
Semantic Scholar
Cell death induced by cationic amphiphilic drugs depends on lysosomal Ca2+ release and cyclic AMP
A. Anand, Bin Liu, J. D. Giacobini, K. Maeda +2 more
2019Molecular Cancer Therapeutics33 citations Open access
Semantic Scholar
Antihistamines and ovarian cancer survival: nationwide cohort study and in vitro cell viability assay.
F. Verdoodt, C. Dehlendorff, M. Jäättelä, R. Strauss +4 more
2019Journal of the National Cancer Institute33 citations Open access
Semantic Scholar
Comprehensive Evaluation of a Quantitative Shotgun Lipidomics Platform for Mammalian Sample Analysis on a High-Resolution Mass Spectrometer.
I. Nielsen, André Vidas Olsen, Jano Dicroce-Giacobini, Elena Papaleo +4 more
2020Journal of the American Society for Mass Spectrometry29 citations Open access
Semantic Scholar
Ragulator—a multifaceted regulator of lysosomal signaling and trafficking
A. Colaco, M. Jäättelä
2017Journal of Cell Biology29 citations Open access
Semantic Scholar
Systematical analysis reveals a strong cancer relevance of CREB1-regulated genes
T. Zheng, Jin-Rong Huang, Xi Xiang, Si-Yuan Li +11 more
2021Cancer Cell International27 citations Open access
Semantic Scholar
Cationic amphiphilic drugs induce elevation in lysoglycerophospholipid levels and cell death in leukemia cells
I. Nielsen, Line Groth-Pedersen, Jano Dicroce-Giacobini, Anna Sofie Holm Jonassen +5 more
2020Metabolomics26 citations
Semantic Scholar
Activation of invasion by oncogenic reprogramming of cholesterol metabolism via increased NPC1 expression and macropinocytosis
Aikaterini Skorda, A. R. Lauridsen, Chengnan Wu, Jinrong Huang +11 more
2023Oncogene25 citations Open access
Semantic Scholar
Ursolic Acid Impairs Cellular Lipid Homeostasis and Lysosomal Membrane Integrity in Breast Carcinoma Cells
D. Fogde, C. P. R. Xavier, Kristina Balnytė, Lya K. K. Holland +6 more
2022Cells25 citations Open access
Semantic Scholar
Visualizing Lysosomal Membrane Permeabilization by Fluorescent Dextran Release.
Anne-Marie Ellegaard, M. Jäättelä, J. Nylandsted
2015Cold Spring Harbor Protocols25 citations
Semantic Scholar
Discovery of small molecules that induce lysosomal cell death in cancer cells using a phenotypic screening platform
Romina J. Pagliero, Diego S. D'Astolfo, Daphne Lelieveld, R. D. Pratiwi +6 more
2016Assay and drug development technologies23 citations Open access
Semantic Scholar
Cationic amphiphilic antihistamines inhibit STAT3 via Ca2+-dependent lysosomal H+ efflux
Bin Liu, Ran Chen, Yi-Dan Zhang, Jinrong Huang +4 more
2023Cell Reports22 citations Open access
Semantic Scholar
Annexin A7 mediates lysosome repair independently of ESCRT-III
M. L. Ebstrup, S. L. Sønder, D. Fogde, Anne Sofie B. Heitmann +5 more
2024Frontiers in Cell and Developmental Biology21 citations Open access
Semantic Scholar
Let-7 microRNA controls invasion-promoting lysosomal changes via the oncogenic transcription factor myeloid zinc finger-1
S. Tvingsholm, M. Hansen, K. B. Clemmensen, D. M. Brix +8 more
2018Oncogenesis21 citations Open access
Semantic Scholar
Release of transcriptional repression via ErbB2-induced, SUMO-directed phosphorylation of Myeloid Zinc Finger-1 Serine 27 activates lysosome redistribution and invasion
D. M. Brix, S. Tvingsholm, M. Hansen, K. B. Clemmensen +12 more
2019Oncogene19 citations Open access
Semantic Scholar
Human P2Y11 Expression Level Affects Human P2X7 Receptor-Mediated Cell Death
Karin Dreisig, Louise Sund, Maja Wallentin Dommer, N. Kristensen +7 more
2018Frontiers in Immunology18 citations Open access
Semantic Scholar

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