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J. Nylandsted · SciRah

Researcher profile · Semantic Scholar

J. Nylandsted

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J. Nylandsted — researcher profile on SciRah

h-index: 38
Works: 109
Citations: 11K

Most-cited papers

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
D. Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, M. Abdellatif +496 more
2021Autophagy4,016 citations Open access
Semantic Scholar
Heat Shock Protein 70 Promotes Cell Survival by Inhibiting Lysosomal Membrane Permeabilization
J. Nylandsted, M. Gyrd-Hansen, A. Danielewicz, Nicole Fehrenbacher +6 more
2004Journal of Experimental Medicine573 citations Open access
Semantic Scholar
Hsp70 stabilizes lysosomes and reverts Niemann–Pick disease-associated lysosomal pathology
T. Kirkegaard, A. G. Roth, N. H. T. Petersen, A. Mahalka +9 more
2010Nature512 citations Open access
Semantic Scholar
Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms.
M. Rohde, M. Daugaard, M. H. Jensen, K. Helin +2 more
2005Genes & Development445 citations Open access
Semantic Scholar
Transformation-associated changes in sphingolipid metabolism sensitize cells to lysosomal cell death induced by inhibitors of acid sphingomyelinase.
N. H. T. Petersen, Ole Dines Olsen, Line Groth-Pedersen, Anne-Marie Ellegaard +14 more
2013Cancer Cell327 citations Open access
Semantic Scholar
Plasma membrane integrity in health and disease: significance and therapeutic potential
Catarina Dias, J. Nylandsted
2021Cell Discovery247 citations Open access
Semantic Scholar
S100A11 is required for efficient plasma membrane repair and survival of invasive cancer cells
J. Jaiswal, S. Lauritzen, Luana Scheffer, M. Sakaguchi +5 more
2014Nature Communications216 citations Open access
Semantic Scholar
Vincristine induces dramatic lysosomal changes and sensitizes cancer cells to lysosome-destabilizing siramesine.
Line Groth-Pedersen, M. Ostenfeld, M. Høyer-Hansen, J. Nylandsted +1 more
2007Cancer Research208 citations Open access
Semantic Scholar
Anti-cancer agent siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation
M. Ostenfeld, M. Høyer-Hansen, L. Bastholm, Nicole Fehrenbacher +7 more
2008Autophagy163 citations Open access
Semantic Scholar
Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair
T. Boye, K. Maeda, W. Pezeshkian, S. L. Sønder +4 more
2017Nature Communications150 citations Open access
Semantic Scholar
Annexins—a family of proteins with distinctive tastes for cell signaling and membrane dynamics
Volker Gerke, Felicity N. E. Gavins, Michael Geisow, T. Grewal +3 more
2024Nature Communications139 citations Open access
Semantic Scholar
Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization
Sonia Hernández‐Tiedra, G. Fabriàs, D. Dávila, Iñigo J. Salanueva +22 more
2016Autophagy135 citations Open access
Semantic Scholar
Repurposing Cationic Amphiphilic Antihistamines for Cancer Treatment
Anne-Marie Ellegaard, C. Dehlendorff, A. Vind, A. Anand +8 more
2016EBioMedicine135 citations Open access
Semantic Scholar
ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression.
B. Rafn, C. F. Nielsen, S. H. Andersen, P. Szyniarowski +13 more
2012Molecules and Cells135 citations Open access
Semantic Scholar
Heat Shock Protein 70 Promotes Cancer Cell Viability by Safeguarding Lysosomal Integrity
M. Gyrd-Hansen, J. Nylandsted, M. Jäättelä
2004Cell Cycle132 citations Open access
Semantic Scholar
BAMLET Activates a Lysosomal Cell Death Program in Cancer Cells
P. Rammer, Line Groth-Pedersen, T. Kirkegaard, M. Daugaard +7 more
2010Molecular Cancer Therapeutics126 citations Open access
Semantic Scholar
Depletion of Kinesin 5B Affects Lysosomal Distribution and Stability and Induces Peri-Nuclear Accumulation of Autophagosomes in Cancer Cells
Carla M. P. Cardoso, Line Groth-Pedersen, M. Høyer-Hansen, T. Kirkegaard +4 more
2009PLoS ONE117 citations Open access
Semantic Scholar
Apoptosome-Independent Activation of the Lysosomal Cell Death Pathway byCaspase-9
M. Gyrd-Hansen, T. Farkas, Nicole Fehrenbacher, L. Bastholm +7 more
2006Molecular and Cellular Biology114 citations Open access
Semantic Scholar
NBCn1 and NHE1 expression and activity in DeltaNErbB2 receptor-expressing MCF-7 breast cancer cells: contributions to pHi regulation and chemotherapy resistance.
G. Lauritzen, M. F. Jensen, E. Boedtkjer, R. Dybboe +3 more
2010Experimental Cell Research113 citations
Semantic Scholar
Annexin A7 is required for ESCRT III-mediated plasma membrane repair
S. L. Sønder, T. Boye, R. Tölle, J. Dengjel +5 more
2019Scientific Reports95 citations Open access
Semantic Scholar
Annexins are instrumental for efficient plasma membrane repair in cancer cells.
S. Lauritzen, T. Boye, J. Nylandsted
2015Seminars in Cell and Developmental Biology94 citations
Semantic Scholar
Methods for the functional quantification of lysosomal membrane permeabilization: a hallmark of lysosomal cell death
S. Aits, M. Jäättelä, J. Nylandsted
2015Methods in Cell Biology87 citations Open access
Semantic Scholar
Annexins induce curvature on free-edge membranes displaying distinct morphologies
T. Boye, J. Jeppesen, K. Maeda, W. Pezeshkian +3 more
2018Scientific Reports84 citations Open access
Semantic Scholar
Identification of Cytoskeleton-Associated Proteins Essential for Lysosomal Stability and Survival of Human Cancer Cells
Line Groth-Pedersen, S. Aits, Elisabeth Corcelle-Termeau, N. H. T. Petersen +2 more
2012PLoS ONE82 citations Open access
Semantic Scholar
Annexins in plasma membrane repair
T. Boye, J. Nylandsted
2016Biological chemistry81 citations
Semantic Scholar
A comprehensive siRNA screen for kinases that suppress macroautophagy in optimal growth conditions
P. Szyniarowski, Elisabeth Corcelle-Termeau, T. Farkas, M. Høyer-Hansen +3 more
2011Autophagy80 citations Open access
Semantic Scholar
Calcium electroporation and electrochemotherapy for cancer treatment: Importance of cell membrane composition investigated by lipidomics, calorimetry and in vitro efficacy
K. L. Hoejholt, T. Mužić, S. D. Jensen, L. T. Dalgaard +5 more
2019Scientific Reports78 citations Open access
Semantic Scholar
S100 and annexin proteins identify cell membrane damage as the Achilles heel of metastatic cancer cells
J. Jaiswal, J. Nylandsted
2015Cell Cycle67 citations Open access
Semantic Scholar
Sunitinib and SU11652 Inhibit Acid Sphingomyelinase, Destabilize Lysosomes, and Inhibit Multidrug Resistance
Anne-Marie Ellegaard, Line Groth-Pedersen, V. Oorschot, J. Klumperman +3 more
2013Molecular Cancer Therapeutics67 citations Open access
Semantic Scholar
Restructuring of the plasma membrane upon damage by LC3-associated macropinocytosis
S. L. Sønder, Swantje Christin Häger, Anne Sofie B. Heitmann, L. B. Frankel +3 more
2021Science Advances61 citations Open access
Semantic Scholar
Filopodia rotate and coil by actively generating twist in their actin shaft
N. Leijnse, Younes F. Barooji, M. Arastoo, S. L. Sønder +8 more
2020Nature Communications47 citations Open access
Semantic Scholar
The Na+/H+ Exchanger, NHE1, Differentially Regulates Mitogen-Activated Protein Kinase Subfamilies after Osmotic Shrinkage in Ehrlich Lettre Ascites Cells
S. Pedersen, B. V. Darborg, Maria Rasmussen, J. Nylandsted +1 more
2007Cellular Physiology and Biochemistry44 citations
Semantic Scholar
Lack of neuroprotection by heat shock protein 70 overexpression in a mouse model of global cerebral ischemia
T. Olsson, O. Hansson, J. Nylandsted, M. Jäättelä +2 more
2004Experimental Brain Research41 citations
Semantic Scholar
Interdisciplinary Synergy to Reveal Mechanisms of Annexin-Mediated Plasma Membrane Shaping and Repair
P. Bendix, A. C. Simonsen, Christoffer D. Florentsen, Swantje Christin Häger +13 more
2020Cells35 citations Open access
Semantic Scholar
Actin Cytoskeletal Dynamics in Single-Cell Wound Repair
M. L. Ebstrup, Catarina Dias, Anne Sofie B. Heitmann, S. L. Sønder +1 more
2021International Journal of Molecular Sciences32 citations Open access
Semantic Scholar
Curvature- and Phase-Induced Protein Sorting Quantified in Transfected Cell-Derived Giant Vesicles.
Guillermo Moreno-Pescador, Christoffer D. Florentsen, Henrik Østbye, S. L. Sønder +7 more
2019ACS Nano32 citations
Semantic Scholar
Repurposing phenothiazines for cancer therapy: compromising membrane integrity in cancer cells
Syrina F Mehrabi, Sabina Elmi, J. Nylandsted
2023Frontiers in Oncology30 citations Open access
Semantic Scholar
ErbB2‐associated changes in the lysosomal proteome
J. Nylandsted, A. C. Becker, J. Bunkenborg, Jens S. Andersen +2 more
2011Proteomics28 citations Open access
Semantic Scholar
Annexin A4 trimers are recruited by high membrane curvatures in Giant Plasma Membrane Vesicles
Christoffer D. Florentsen, Alexander Kamp-Sonne, Guillermo Moreno-Pescador, W. Pezeshkian +4 more
2020bioRxiv27 citations Open access
Semantic Scholar
Annexins: players of single cell wound healing and regeneration
Swantje Christin Häger, J. Nylandsted
2019Communicative & Integrative Biology25 citations Open access
Semantic Scholar
Visualizing Lysosomal Membrane Permeabilization by Fluorescent Dextran Release.
Anne-Marie Ellegaard, M. Jäättelä, J. Nylandsted
2015Cold Spring Harbor Protocols25 citations
Semantic Scholar
Phenothiazines alter plasma membrane properties and sensitize cancer cells to injury by inhibiting annexin-mediated repair
Anne Sofie B. Heitmann, Ali Asghar Hakami Zanjani, Martin Berg Klenow, Anna Mularski +8 more
2021Journal of Biological Chemistry23 citations Open access
Semantic Scholar
Annexin A7 mediates lysosome repair independently of ESCRT-III
M. L. Ebstrup, S. L. Sønder, D. Fogde, Anne Sofie B. Heitmann +5 more
2024Frontiers in Cell and Developmental Biology21 citations Open access
Semantic Scholar
Liprotides kill cancer cells by disrupting the plasma membrane
H. S. Frislev, T. Boye, J. Nylandsted, D. Otzen
2017Scientific Reports20 citations Open access
Semantic Scholar
Plasma membrane integrity in health and disease: significance and therapeutic potential
Catarina Dias, J. Nylandsted
2021Cell Discovery19 citations Open access
Semantic Scholar
Annexins A1 and A2 Accumulate and Are Immobilized at Cross-Linked Membrane-Membrane Interfaces.
Martin Berg Klenow, Christoffer Iversen, Frederik Wendelboe Lund, Anna Mularski +4 more
2021Biochemistry18 citations
Semantic Scholar
Annexins Bend Wound Edges during Plasma Membrane Repair.
A. C. Simonsen, T. Boye, J. Nylandsted
2020Current Medicinal Chemistry15 citations
Semantic Scholar
Timescale of hole closure during plasma membrane repair estimated by calcium imaging and numerical modeling
Martin Berg Klenow, Anne Sofie B. Heitmann, J. Nylandsted, A. C. Simonsen
2021Scientific Reports14 citations Open access
Semantic Scholar
Quantitative Profiling of Lysosomal Lipidome by Shotgun Lipidomics.
M. Bilgin, J. Nylandsted, M. Jäättelä, K. Maeda
2017Methods in molecular biology14 citations
Semantic Scholar
Quantification of Lysosomal Membrane Permeabilization by Cytosolic Cathepsin and β-N-Acetyl-Glucosaminidase Activity Measurements.
M. Jäättelä, J. Nylandsted
2015Cold Spring Harbor Protocols13 citations Open access
Semantic Scholar

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