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M. Osawa · SciRah

Researcher profile · Semantic Scholar

M. Osawa

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M. Osawa — researcher profile on SciRah

h-index: 31
Works: 87
Citations: 6,436

Most-cited papers

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
Sheng Zhou, J. Schuetz, K. Bunting, A. Colapietro +7 more
2001Nature Medicine2,415 citations
Semantic Scholar
Functional skeletal muscle regeneration from differentiating embryonic stem cells
Radbod Darabi, Kimberly Gehlbach, R. Bachoo, S. Kamath +4 more
2008Nature Medicine340 citations
Semantic Scholar
Induced Pluripotent Stem Cells and Their Use in Human Models of Disease and Development.
Peter Karagiannis, Kazutoshi Takahashi, M. Saito, Y. Yoshida +10 more
2019Physiological Reviews311 citations
Semantic Scholar
Fcα/μ receptor mediates endocytosis of IgM-coated microbes
A. Shibuya, N. Sakamoto, Y. Shimizu, K. Shibuya +13 more
2000Nature Immunology302 citations
Semantic Scholar
Conversion of biliary system to pancreatic tissue in Hes1-deficient mice
R. Sumazaki, N. Shiojiri, Shigemi Isoyama, M. Masu +5 more
2004Nature Genetics243 citations
Semantic Scholar
Essential and Instructive Roles of GATA Factors in Eosinophil Development
R. Hirasawa, R. Shimizu, Satoru Takahashi, M. Osawa +9 more
2002Journal of Experimental Medicine227 citations Open access
Semantic Scholar
Quantification of self-renewal capacity in single hematopoietic stem cells from normal and Lnk-deficient mice.
Hideo Ema, K. Sudo, J. Seita, Azusa Matsubara +5 more
2005Developmental Cell219 citations Open access
Semantic Scholar
A Role for Pref-1 and HES-1 in Thymocyte Development
M. Kaneta, M. Osawa, M. Osawa, K. Sudo +3 more
2000Journal of Immunology217 citations Open access
Semantic Scholar
Recapitulating the human segmentation clock with pluripotent stem cells
Mitsuhiro Matsuda, Yoshihiro Yamanaka, Maya Uemura, M. Osawa +18 more
2020Nature164 citations Open access
Semantic Scholar
Erythroid expansion mediated by the Gfi-1B zinc finger protein: role in normal hematopoiesis.
M. Osawa, Tomoyuki Yamaguchi, Yukio Nakamura, S. Kaneko +6 more
2002Blood152 citations Open access
Semantic Scholar
Reciprocal Roles for CCAAT/Enhancer Binding Protein (C/EBP) and PU.1 Transcription Factors in Langerhans Cell Commitment
A. Iwama, M. Osawa, R. Hirasawa, N. Uchiyama +7 more
2002Journal of Experimental Medicine121 citations Open access
Semantic Scholar
Identification of a High‐Frequency Somatic NLRC4 Mutation as a Cause of Autoinflammation by Pluripotent Cell–Based Phenotype Dissection
Yuri Kawasaki, H. Oda, Jun Ito, A. Niwa +15 more
2017Arthritis & Rheumatology120 citations
Semantic Scholar
Role of Dok-1 and Dok-2 in Myeloid Homeostasis and Suppression of Leukemia
T. Yasuda, M. Shirakata, A. Iwama, A. Ishii +12 more
2004Journal of Experimental Medicine119 citations Open access
Semantic Scholar
Paired Activating and Inhibitory Immunoglobulin-like Receptors, MAIR-I and MAIR-II, Regulate Mast Cell and Macrophage Activation
K. Yotsumoto, Y. Okoshi, K. Shibuya, S. Yamazaki +9 more
2003Journal of Experimental Medicine119 citations Open access
Semantic Scholar
Role of SOX17 in hematopoietic development from human embryonic stem cells.
Yaeko Nakajima-Takagi, M. Osawa, M. Oshima, Haruna Takagi +9 more
2013Blood101 citations Open access
Semantic Scholar
Dok-1 and Dok-2 are negative regulators of T cell receptor signaling.
T. Yasuda, K. Bundo, A. Hino, K. Honda +8 more
2007International Immunology98 citations
Semantic Scholar
Endomucin, a CD34-like sialomucin, marks hematopoietic stem cells throughout development
Azusa Matsubara, A. Iwama, S. Yamazaki, C. Furuta +9 more
2005Journal of Experimental Medicine88 citations Open access
Semantic Scholar
Acetyl-coenzyme A synthetase is a lipogenic enzyme controlled by SREBP-1 and energy status.
H. Sone, H. Shimano, Y. Sakakura, Noriyuki Inoue +10 more
2002American Journal of Physiology. Endocrinology and Metabolism88 citations
Semantic Scholar
Hematopoietic stem cells express Tie-2 receptor in the murine fetal liver.
Hsiang-Chun Hsu, Hideo Ema, M. Osawa, Yukio Nakamura +2 more
2000Blood74 citations
Semantic Scholar
Deficiency of the macrophage migration inhibitory factor gene has no significant effect on endotoxaemia
N. Honma, H. Koseki, T. Akasaka, T. Nakayama +5 more
2000Immunology70 citations Open access
Semantic Scholar
Ex Vivo Expansion of Human Hematopoietic Stem Cells by Garcinol, a Potent Inhibitor of Histone Acetyltransferase
T. Nishino, Chang-Shan Wang, M. Mochizuki-Kashio, M. Osawa +2 more
2011PLoS ONE63 citations Open access
Semantic Scholar
Genome-wide analysis of target genes regulated by HoxB4 in hematopoietic stem and progenitor cells developing from embryonic stem cells.
M. Oshima, Mitsuhiro Endoh, Takaho A. Endo, Tetsuro Toyoda +6 more
2011Blood56 citations Open access
Semantic Scholar
Pluripotent stem cell models of Blau syndrome reveal an IFN‐&ggr;–dependent inflammatory response in macrophages
S. Takada, N. Kambe, Yuri Kawasaki, A. Niwa +13 more
2018Journal of Allergy and Clinical Immunology50 citations Open access
Semantic Scholar
A JAK2 Interdomain Linker Relays Epo Receptor Engagement Signals to Kinase Activation*
Lequn Zhao, Hong-Yun Dong, Cheng-Cheng Zhang, Lisa N. Kinch +5 more
2009Journal of Biological Chemistry46 citations Open access
Semantic Scholar
Bmi1 Confers Resistance to Oxidative Stress on Hematopoietic Stem Cells
Shunsuke Nakamura, M. Oshima, Jin Yuan, A. Saraya +7 more
2012PLoS ONE44 citations Open access
Semantic Scholar
Rescue of recurrent deep intronic mutation underlying cell type–dependent quantitative NEMO deficiency
B. Boisson, Yoshitaka Honda, M. Ajiro, J. Bustamante +24 more
2018Journal of Clinical Investigation43 citations Open access
Semantic Scholar
Improved Sendai viral system for reprogramming to naive pluripotency
Akira Kunitomi, Ryoko Hirohata, Vanessa Arreola, M. Osawa +10 more
2022Cell Reports Methods41 citations Open access
Semantic Scholar
Tumor necrosis factor-α inhibits generation of glycophorin A+ cells by CD34+ cells
Wei-Guo Xiao, K. Koizumi, M. Nishio, T. Endo +6 more
200241 citations Open access
Semantic Scholar
Trapping of CDC42 C-terminal variants in the Golgi drives pyrin inflammasome hyperactivation
M. Nishitani-Isa, Kojiro Mukai, Yoshitaka Honda, H. Nihira +19 more
2022Journal of Experimental Medicine36 citations Open access
Semantic Scholar
Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency.
Anfeng Mu, Asuka Hira, A. Niwa, M. Osawa +15 more
2021Blood34 citations Open access
Semantic Scholar
Sox17-Mediated Maintenance of Fetal Intra-Aortic Hematopoietic Cell Clusters
I. Nobuhisa, M. Osawa, Mami Uemura, Y. Kishikawa +8 more
2014Molecular and Cellular Biology31 citations Open access
Semantic Scholar
Synthetic immune checkpoint engagers protect HLA-deficient iPSCs and derivatives from innate immune cell cytotoxicity.
A. Gravina, G. Tediashvili, Yue-Ting Zheng, Kumiko A. Iwabuchi +7 more
2023Cell Stem Cell29 citations Open access
Semantic Scholar
Bi-allelic loss of function variants of TBX6 causes a spectrum of malformation of spine and rib including congenital scoliosis and spondylocostal dysostosis
N. Otomo, K. Takeda, Shunsuke Kawai, I. Kou +25 more
2019Journal of Medical Genetics20 citations
Semantic Scholar
Functional evaluation of the pathological significance of MEFV variants using induced pluripotent stem cell-derived macrophages.
T. Shiba, Takayuki Tanaka, H. Ida, Misa Watanabe +10 more
2019Journal of Allergy and Clinical Immunology20 citations Open access
Semantic Scholar
Increased cell surface expression of C‐terminal truncated erythropoietin receptors in polycythemia
T. Motohashi, Yukio Nakamura, M. Osawa, T. Hiroyama +3 more
2001European Journal of Haematology19 citations
Semantic Scholar
Tumor necrosis factor-alpha inhibits generation of glycophorin A+ cells by CD34+ cells.
Wei-Guo Xiao, K. Koizumi, M. Nishio, T. Endo +6 more
2002Experimental Hematology18 citations
Semantic Scholar
A de novo dominant-negative variant is associated with OTULIN-related autoinflammatory syndrome
Yukiko Takeda, Masahiro Ueki, Junpei Matsuhiro, E. Walinda +18 more
2024Journal of Experimental Medicine17 citations Open access
Semantic Scholar
Human AK2 links intracellular bioenergetic redistribution to the fate of hematopoietic progenitors.
K. Oshima, Norikazu Saiki, Michihiro Tanaka, H. Imamura +23 more
2018Biochemical and Biophysical Research Communications - BBRC17 citations Open access
Semantic Scholar
New approaches to expand hematopoietic stem and progenitor cells
T. Nishino, M. Osawa, A. Iwama
2012Expert Opinion on Biological Therapy17 citations
Semantic Scholar
Retroviral expression screening of oncogenes in natural killer cell leukemia.
Y. Choi, R. Moriuchi, M. Osawa, A. Iwama +11 more
2005Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis16 citations
Semantic Scholar
A disease-specific iPS cell resource for studying rare and intractable diseases
M. Saito, M. Osawa, Nao Tsuchida, Kotaro Shiraishi +7 more
2023Inflammation and Regeneration14 citations Open access
Semantic Scholar
Characterization of the mouse interleukin-13 receptor α1 gene
M. Osawa, S. Miyoshi, N. Copeland, D. J. Gilbert +6 more
2000Immunogenetics14 citations
Semantic Scholar
Impaired erythropoiesis in transgenic mice overexpressing a truncated erythropoietin receptor.
Y. Nakamura, H. Takano, M. Osawa, T. Tomita +7 more
1998Experimental Hematology14 citations
Semantic Scholar
Compromised hematopoiesis and increased DNA damage following non-lethal ionizing radiation of a human hematopoietic system reconstituted in immunodeficient mice
Chang-Shan Wang, Shunsuke Nakamura, M. Oshima, M. Mochizuki-Kashio +7 more
2015International Journal of Radiation Biology13 citations Open access
Semantic Scholar
Molecular cloning and chromosomal mapping of a novel five-span transmembrane protein gene, M83.
T. Motohashi, S. Miyoshi, M. Osawa, H. Eyre +6 more
2000Biochemical and Biophysical Research Communications - BBRC13 citations Open access
Semantic Scholar
Molecular cloning and characterization of mouse Tspan-3, a novel member of the tetraspanin superfamily, expressed on resting dendritic cells.
Yayoi Tokoro, K. Shibuya, M. Osawa, Satoko Tahara-Hanaoka +4 more
2001Biochemical and Biophysical Research Communications - BBRC12 citations Open access
Semantic Scholar
Manipulation of Hematopoietic Stem Cells for Regenerative Medicine
Yaeko Nakajima-Takagi, M. Osawa, A. Iwama
2014The Anatomical Record11 citations
Semantic Scholar
Transcriptional profiling of hematopoietic stem cells by high-throughput sequencing
Yoshimi Yashiro, Hideo Bannai, T. Minowa, Tomohide Yabiku +4 more
2009International journal of hematology10 citations
Semantic Scholar
StemPanTox: A fast and wide-target drug assessment system for tailor-made safety evaluations using personalized iPS cells
Junko Yamane, Takumi Wada, Hironori Otsuki, K. Inomata +10 more
2022iScience9 citations Open access
Semantic Scholar
Involvement of mTOR pathway in neurodegeneration in NSF-related developmental and epileptic encephalopathy
Takahiro Hayashi, N. Yano, K. Kora, Atsushi Yokoyama +13 more
2023Human Molecular Genetics8 citations Open access
Semantic Scholar

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