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D. Irlbeck · SciRah

Researcher profile · Semantic Scholar

D. Irlbeck

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D. Irlbeck — researcher profile on SciRah

h-index: 16
Works: 25
Citations: 1,514

Most-cited papers

Minority HIV-1 Drug Resistance Mutations Are Present in Antiretroviral Treatment–Naïve Populations and Associate with Reduced Treatment Efficacy
Jeffrey A. Johnson, Jin-Fen Li, Xierong Wei, Jonathan T Lipscomb +8 more
2008PLoS Medicine417 citations Open access
Semantic Scholar
Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo
Christopher C. Nixon, M. Mavigner, G. Sampey, A. Brooks +39 more
2020Nature269 citations Open access
Semantic Scholar
Vaccination of Macaques against Pathogenic Simian Immunodeficiency Virus with Venezuelan Equine Encephalitis Virus Replicon Particles
N. Davis, I. Caley, K. Brown, M. Betts +8 more
2000Journal of Virology211 citations Open access
Semantic Scholar
Humoral, mucosal, and cellular immunity in response to a human immunodeficiency virus type 1 immunogen expressed by a Venezuelan equine encephalitis virus vaccine vector
I. Caley, Michael R. Betts, D. Irlbeck, N. Davis +3 more
1997Journal of Virology132 citations Open access
Semantic Scholar
Long-Term Results of Initial Therapy With Abacavir and Lamivudine Combined With Efavirenz, Amprenavir/Ritonavir, or Stavudine
J. Bartlett, Judy Johnson, G. Herrera, N. Sosa +5 more
2006Journal of Acquired Immune Deficiency Syndromes76 citations Open access
Semantic Scholar
Selection of High-Level Resistance to Human Immunodeficiency Virus Type 1 Protease Inhibitors
T. Watkins, W. Resch, D. Irlbeck, R. Swanstrom
2003Antimicrobial Agents and Chemotherapy59 citations Open access
Semantic Scholar
Effect of concurrent zidovudine use on the resistance pathway selected by abacavir‐containing regimens
E. Lanier, N. Givens, C. Stone, P. Griffin +7 more
2004HIV Medicine40 citations
Semantic Scholar
Interplay between Single Resistance-Associated Mutations in the HIV-1 Protease and Viral Infectivity, Protease Activity, and Inhibitor Sensitivity
Gavin J. Henderson, Sook-Kyung Lee, D. Irlbeck, Janera Harris +4 more
2011Antimicrobial Agents and Chemotherapy39 citations Open access
Semantic Scholar
Vaccination of Macaques against Pathogenic Simian Immunodeficiency Virus with Venezuelan Equine Encephalitis Virus Replicon Particles
N. Davis, I. Caley, K. Brown, M. Betts +8 more
2000Journal of Virology39 citations Open access
Semantic Scholar
Combined noncanonical NF-κB agonism and targeted BET bromodomain inhibition reverse HIV latency ex vivo
S. Falcinelli, J. Peterson, Anne-Marie W. Turner, D. Irlbeck +27 more
2022Journal of Clinical Investigation31 citations Open access
Semantic Scholar
Th17 cell master transcription factor RORC2 regulates HIV-1 gene expression and viral outgrowth
T. R. Wiche Salinas, Yu-Wei Zhang, Daniele Sarnello, A. Zhyvoloup +12 more
2021Proceedings of the National Academy of Sciences of the United States of America30 citations Open access
Semantic Scholar
Chemokine (C-C motif) receptor 5-using envelopes predominate in dual/mixed-tropic HIV from the plasma of drug-naive individuals
D. Irlbeck, H. Amrine-Madsen, K. Kitrinos, C. Labranche +1 more
2008AIDS (London)30 citations Open access
Semantic Scholar
The HIV Type 1 Protease Inhibitor Saquinavir Can Select for Multiple Mutations that Confer Increasing Resistance
M. Vaillancourt, D. Irlbeck, Terri Smith, R. Coombs +1 more
1999AIDS Research and Human Retroviruses30 citations
Semantic Scholar
Synthesis and Biological Evaluation of Macrocyclized Betulin Derivatives as a Novel Class of Anti-HIV-1 Maturation Inhibitors
Jun Tang, Stacey A. Jones, J. L. Jeffery, Sonia R. Miranda +17 more
2014Open Medicinal Chemistry Journal24 citations Open access
Semantic Scholar
Discovery of a novel and potent class of anti-HIV-1 maturation inhibitors with improved virology profile against gag polymorphisms.
Jun Tang, Stacey A. Jones, J. Jeffrey, Sonia R. Miranda +5 more
2017Bioorganic & Medicinal Chemistry Letters20 citations
Semantic Scholar
The SMAC Mimetic AZD5582 is a Potent HIV Latency Reversing Agent
G. Sampey, D. Irlbeck, E. Browne, Matt Kanke +9 more
2018bioRxiv18 citations Open access
Semantic Scholar
Virologic Failure in First-Line Human Immunodeficiency Virus Therapy with a CCR5 Entry Inhibitor, Aplaviroc, plus a Fixed-Dose Combination of Lamivudine-Zidovudine: Nucleoside Reverse Transcriptase Inhibitor Resistance Regardless of Envelope Tropism
James F. Demarest, H. Amrine-Madsen, D. Irlbeck, K. Kitrinos
2008Antimicrobial Agents and Chemotherapy15 citations Open access
Semantic Scholar
Salvage Therapy With Abacavir and Other Reverse Transcriptase Inhibitors for Human Immunodeficiency-Associated Encephalopathy
J. Saavedra-Lozano, J. Ramos, F. Sanz, M. Navarro +10 more
2006The Pediatric Infectious Disease Journal14 citations
Semantic Scholar
No association found between the detection of either xenotropic murine leukemia virus-related virus or polytropic murine leukemia virus and chronic fatigue syndrome in a blinded, multi-site, prospective study by the establishment and use of the SolveCFS BioBank
D. Irlbeck, S. Vernon, K. McCleary, L. Bateman +7 more
2014BMC Research Notes13 citations Open access
Semantic Scholar
Patients experiencing early virologic failure on a protease inhibitor- or nonnucleoside reverse transcriptase inhibitor-based initial regimen containing a thymidine analogue and Lamivudine can be successfully treated with a quadruple-nucleoside regimen.
Allana Rodriguez, Christina E. Hill-Zabala, Louis M. Sloan, T. Jefferson +4 more
2006Journal of Acquired Immune Deficiency Syndromes7 citations Open access
Semantic Scholar
Efficacy and Safety of Abacavir/Lamivudine/Zidovudine Plus Tenofovir in HBV/HIV-1 Coinfected Adults: 48-Week Data
Allan E. Rodriguez, E. Dejesus, V. Williams, D. Irlbeck +3 more
2010Open AIDS Journal4 citations Open access
Semantic Scholar
In vitro demonstration of a potential role for STING agonist in HIV cure
A. Koblansky, S. Raines, J. Schawalder, D. Irlbeck +5 more
20190 citations Open access
Semantic Scholar
Combinatorial latency reversal activity of inhibitor of apoptosis antagonists with mechanistically distinct classes of HIV latency reversal agents
S. Falcinelli, D. Irlbeck, Anne-Marie W. Turner, F. Potjewyd +4 more
20190 citations Open access
Semantic Scholar
The SMAC mimetic AZD5582 reverses HIV latency as a single agent in resting primary CD4+ T cells
G. Sampey, D. Irlbeck, E. Browne, M. Kanke +16 more
2019Journal of virus eradication0 citations Open access
Semantic Scholar
Erratum: The HIV-1 protease inhibitor saquinavir can select for multiple mutations that confer increasing resistance (Aids Research and Human Retroviruses (1999) 15:4 (355-363))
M. Vaillancourt, D. Irlbeck, T. Smith, R. Coombs +1 more
19990 citations
Semantic Scholar

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