A. Zhyvoloup

Most-cited papers

1. The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer .

   A. Folkes, K. Ahmadi, W. Alderton, Sonia Alix +30 more

   2008Journal of Medicinal Chemistry767 citations Open access

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2. Biological properties of potent inhibitors of class I phosphatidylinositide 3-kinases: from PI-103 through PI-540, PI-620 to the oral agent GDC-0941

   F. Raynaud, S. Eccles, Sonal Patel, Sonia Alix +20 more

   2009Molecular Cancer Therapeutics283 citations Open access

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3. Heat shock protein 90 controls HIV-1 reactivation from latency

   Ian Anderson, J. Low, S. Weston, Michael Weinberger +7 more

   2014Proceedings of the National Academy of Sciences of the United States of America118 citations Open access

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4. Evaluation of the genetic diversity among elite tea (Camellia sinensis var. sinensis) accessions using RAPD markers

   S. S. Kaundun, A. Zhyvoloup, Young-Goo Park

   2004Euphytica77 citations

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5. Use of the bulked genomic DNA-based RAPD methodology to assess the genetic diversity among abandoned Korean tea plantations

   Young-Goo Park, S. S. Kaundun, A. Zhyvoloup

   2002Genetic Resources and Crop Evolution31 citations

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6. Th17 cell master transcription factor RORC2 regulates HIV-1 gene expression and viral outgrowth

   T. R. Wiche Salinas, Yu-Wei Zhang, Daniele Sarnello, A. Zhyvoloup +12 more

   2021Proceedings of the National Academy of Sciences of the United States of America30 citations Open access

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7. Digoxin reveals a functional connection between HIV-1 integration preference and T-cell activation

   A. Zhyvoloup, A. Melamed, Ian Anderson, D. Planas +8 more

   2017PLoS Pathogens25 citations Open access

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8. Expression of SSX2 tumor antigen in baculovirus expression system and its application for screening of blood serum of melanoma patients.

   R. Kyyamova, V. Gryshkova, A. Zhyvoloup

   2006Experimental oncology1 citations

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9. A capsid-dependent integration program linking T cell activation to HIV-1 gene expression

   A. Zhyvoloup, A. Melamed, Ian Anderson, D. Planas +7 more

   20160 citations

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10. The novel potent PI3 Kinase inhibitors, PI-540 and PI-620: Activity in vitro and in vivo

    Sonal Patel, F. Rojo, Letitia Lensun, Giles Pergl-Wilson +8 more

    20080 citations

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11. 320 Identification of potent, selective, soluble and permeable small molecule PI3 kinase inhibitors for the treatment of cancer

    K. Ahmadi, W. Alderton, Irina S. Chuckowree, P. Depledge +8 more

    20040 citations

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