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B. Hare · SciRah

Researcher profile · Semantic Scholar

B. Hare

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B. Hare — researcher profile on SciRah

h-index: 14
Works: 39
Citations: 1,650

Most-cited papers

The crystal structure of a T cell receptor in complex with peptide and MHC class II.
E. Reinherz, K. Tan, Lei Tang, P. Kern +10 more
1999Science454 citations
Semantic Scholar
Potentiation of tumor responses to DNA damaging therapy by the selective ATR inhibitor VX-970
Amy B. Hall, D. Newsome, Yuxin Wang, D. Boucher +16 more
2014OncoTarget186 citations Open access
Semantic Scholar
Phase I Trial of First-in-Class ATR Inhibitor M6620 (VX-970) as Monotherapy or in Combination With Carboplatin in Patients With Advanced Solid Tumors
T. Yap, Brent O'Carrigan, M. Penney, J. Lim +19 more
2020Journal of Clinical Oncology181 citations Open access
Semantic Scholar
Pim-1 Ligand-bound Structures Reveal the Mechanism of Serine/Threonine Kinase Inhibition by LY294002*
M. Jacobs, J. Black, O. Futer, L. Swenson +3 more
2005Journal of Biological Chemistry180 citations Open access
Semantic Scholar
A structurally unrelated mimic of a Pseudomonas aeruginosa acyl-homoserine lactone quorum-sensing signal
U. Müh, B. Hare, B. Duerkop, M. Schuster +4 more
2006Proceedings of the National Academy of Sciences of the United States of America130 citations Open access
Semantic Scholar
Structure, specificity and CDR mobility of a class II restricted single-chain T-cell receptor
B. Hare, D. Wyss, M. Osburne, P. Kern +2 more
1999Nature Structural Biology90 citations
Semantic Scholar
A Multi-Variant, Viral Dynamic Model of Genotype 1 HCV to Assess the in vivo Evolution of Protease-Inhibitor Resistant Variants
B. Adiwijaya, E. Herrmann, B. Hare, Tara L. Kieffer +7 more
2010PLoS Comput. Biol.78 citations Open access
Semantic Scholar
Classifying protein kinase structures guides use of ligand‐selectivity profiles to predict inactive conformations: Structure of lck/imatinib complex
Marc D. Jacobs, P. Caron, B. Hare
2007Proteins: Structure, Function, and Bioinformatics77 citations
Semantic Scholar
Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma
F. Foijer, L. Albacker, B. Bakker, D. Spierings +11 more
2017eLife55 citations Open access
Semantic Scholar
Rapid decrease of wild-type hepatitis C virus on telaprevir treatment
B. Adiwijaya, B. Hare, P. Caron, J. Randle +4 more
2008Antiviral Therapy42 citations
Semantic Scholar
Phase I trial of a first-in-class ATR inhibitor VX-970 as monotherapy (mono) or in combination (combo) with carboplatin (CP) incorporating pharmacodynamics (PD) studies.
Brent O'Carrigan, M. D. De Miguel Luken, D. Papadatos-Pastos, Jessica Brown +16 more
201636 citations
Semantic Scholar
Activation of the human histamine H2 receptor is linked to cell proliferation and c- fos gene transcription.
Li-Dong Wang, M. Hoeltzel, Kenneth Butler, B. Hare +3 more
1997American Journal of Physiology - Cell Physiology36 citations
Semantic Scholar
CORES: an automated method for generating three-dimensional models of protein/ligand complexes.
B. Hare, W. Walters, P. Caron, G. Bemis
2004Journal of Medicinal Chemistry30 citations
Semantic Scholar
4-(Benzimidazol-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: potent and selective p70S6 kinase inhibitors.
U. Bandarage, B. Hare, J. Parsons, L. Pham +12 more
2009Bioorganic & Medicinal Chemistry Letters22 citations Open access
Semantic Scholar
Application of automated NOE assignment to three-dimensional structure refinement of a 28 kDa single-chain T cell receptor
B. Hare, G. Wagner
1999Journal of Biomolecular NMR13 citations
Semantic Scholar
Abstract 3717: Defining optimal dose schedules for ATR inhibitors in combination with DNA damaging drugs: Informing clinical studies of VX-970, the first-in-class ATR inhibitor
J. Pollard, P. Reaper, Adele Peek, S. Hughes +14 more
20168 citations
Semantic Scholar
Review article: HCV ? STAT-C era of therapy
C. Lange, Chris Sarrazin, S. Zeuzem, M. Fried +496 more
20108 citations
Semantic Scholar
Activation of the human histamine H2 receptor is linked to cell proliferation and c-fos gene transcription.
L.-D. Wang, M. Hoeltzel, K. Butler, B. Hare +3 more
1997American Journal of Physiology7 citations
Semantic Scholar
A signature for immune response correlates with HCV treatment outcome in Caucasian subjects.
B. Hare, E. Haseltine, Mark A. Fleming, Daniel Chelsky +3 more
2015Journal of Proteomics4 citations Open access
Semantic Scholar
CRYSTAL STRUCTURE OF COMPLEX BETWEEN D10 TCR AND PMHC I-AK/CA
E. Reinherz, K. Tan, L. Tang, P. Kern +10 more
19993 citations
Semantic Scholar
A signature for immune response correlates with HCV treatment outcome in Caucasian subjects
B. Hare, E. Haseltine, Mark A. Fleming, Daniel Chelsky +3 more
2015Data in Brief2 citations Open access
Semantic Scholar
Pathogen Flow: What We Need to Know
Charles L. Nunn, B. Hare
2012American Journal of Primatology2 citations
Semantic Scholar
Leveraging X-Ray Structural Information in Gene Family-Based Drug Discovery: Application to Protein Kinases
A. Aronov, Albert C. Pierce, G. Bemis, M. Jacobs +2 more
20072 citations
Semantic Scholar
THU0242 Vx-509 (DECERNOTINIB) Treatment Reduces Levels of Markers for Immune Activation, Bone Degradation and Inflammation but not Interferon Signaling in Patients with Rheumatoid Arthritis
B. Hare, E. Haseltine, D. Takemoto, J. Sullivan +2 more
20141 citations
Semantic Scholar
601 Anti-viral activity of VX-950 resolves expression of an HCV-associated gene signature
R. Ramachandran, B. Hare, K. Kelliher, J. Randle +8 more
20061 citations
Semantic Scholar
A SINGLE-CHAIN T CELL RECEPTOR
B. Hare, D. Wyss, E. Reinherz, G. Wagner
19991 citations
Semantic Scholar
Suzetrigine Is Not Expected to Have Clinically Relevant DDIs with Apixaban and Rivaroxaban Based on PBPK Modeling
Guan-Yu Wang, E. Lakota, Bo Feng, Li-Cong Jiang +2 more
2026Journal of clinical pharmacology0 citations Open access
Semantic Scholar
Author response: Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma
F. Foijer, L. Albacker, B. Bakker, D. Spierings +11 more
20170 citations Open access
Semantic Scholar
Abstract 1644: VX-970, the first-in-class inhibitor of the DNA damage repair enzyme ATR
J. Pollard, P. Reaper, Julie Jones, C. S. Barnes +23 more
20150 citations
Semantic Scholar
Abstract LB-299: Comprehensive preclinical evaluation of VE-822, the first ATR-targeted drug candidate: a novel approach to transforming the efficacy of DNA damaging agents.
D. Boucher, P. Charlton, J. Charrier, Brinley F Furey +12 more
20130 citations
Semantic Scholar
Biomarqueurs pour patients infectés par le hcv
Mark A. Fleming, B. Hare, Daniel Chelsky, R. Allard +1 more
20130 citations
Semantic Scholar
COMMENTARY Pathogen Flow: What We Need to Know
Charles L. Nunn, B. Hare
20120 citations
Semantic Scholar
Abstract 5491: Evaluation of the first potent and highly selective inhibitor of ATR kinase: An approach to selectively sensitize cancer cells to genotoxic drugs
J. Pollard, P. Caron, P. Charlton, J. Charrier +12 more
20110 citations
Semantic Scholar
Crystal structure of Pim-1 bound to staurosporine
M. Jacobs, J. Black, O. Futer, L. Swenson +3 more
20050 citations
Semantic Scholar
Structure of Pim-1 bound to adenosine
M. Jacobs, J. Black, O. Futer, L. Swenson +3 more
20050 citations
Semantic Scholar
Crystal Structure of Pim-1 bound to LY294002
M. Jacobs, J. Black, O. Futer, L. Swenson +3 more
20050 citations
Semantic Scholar
Solution nmr structure of the dimerization domain of the yeast transcriptional activator Gal4 (residues 50-106)
P. Hidalgo, A. Ansari, P. Schmidt, B. Hare +5 more
20010 citations
Semantic Scholar
NMR Structure of IBiD, A Domain of CBP/p300
Charles H. Lin, B. Hare, G. Wagner, S. Harrison +2 more
20010 citations
Semantic Scholar
Structure and dynamics of scTCR investigated by a new NMR structural refinement methodology
A. Kitao, B. Hare, G. Wagner
20000 citations Open access
Semantic Scholar

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