Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

B. Eam · SciRah

Researcher profile · Semantic Scholar

B. Eam

Share profile

B. Eam — researcher profile on SciRah

h-index: 12
Works: 24
Citations: 918

Most-cited papers

Vertical Transmission of Diverse Microbes in the Tropical Sponge Corticium sp
K. Sharp, B. Eam, D. Faulkner, Margo G. Haygood
2006Applied and Environmental Microbiology202 citations Open access
Semantic Scholar
Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition.
S. Reich, P. Sprengeler, Gary G. Chiang, J. Appleman +25 more
2018Journal of Medicinal Chemistry143 citations Open access
Semantic Scholar
Design of Development Candidate eFT226, a First in Class Inhibitor of Eukaryotic Initiation Factor 4A RNA Helicase.
J. Ernst, P. A. Thompson, C. Nilewski, P. Sprengeler +19 more
2020Journal of Medicinal Chemistry122 citations Open access
Semantic Scholar
Tentative T Cells: Memory Cells Are Quick to Respond, but Slow to Divide
J. Whitmire, B. Eam, J. Whitton
2008PLoS Pathogens90 citations Open access
Semantic Scholar
Direct Interferon-γ Signaling Dramatically Enhances CD4+ and CD8+ T Cell Memory1
J. Whitmire, B. Eam, N. Benning, J. Whitton
2007Journal of Immunology88 citations Open access
Semantic Scholar
Targeting Oncogene mRNA Translation in B-Cell Malignancies with eFT226, a Potent and Selective Inhibitor of eIF4A
P. A. Thompson, B. Eam, N. Young, S. Fish +21 more
2020Molecular Cancer Therapeutics41 citations
Semantic Scholar
Increasing the CD4+ T Cell Precursor Frequency Leads to Competition for IFN-γ Thereby Degrading Memory Cell Quantity and Quality1
J. Whitmire, N. Benning, B. Eam, J. Whitton
2008Journal of Immunology41 citations Open access
Semantic Scholar
Zotatifin, an eIF4A-Selective Inhibitor, Blocks Tumor Growth in Receptor Tyrosine Kinase Driven Tumors
A. Gerson‐Gurwitz, N. Young, V. Goel, B. Eam +9 more
2021Frontiers in Oncology40 citations Open access
Semantic Scholar
Direct interferon-gamma signaling dramatically enhances CD4+ and CD8+ T cell memory.
J. Whitmire, B. Eam, N. Benning, J. Whitton
2007Journal of Immunology35 citations
Semantic Scholar
Mice deficient in stem cell antigen-1 (Sca1, Ly-6A/E) develop normal primary and memory CD4+ and CD8+ T cell responses to virus infection
J. Whitmire, B. Eam, J. Whitton
2009European Journal of Immunology27 citations Open access
Semantic Scholar
Akt Regulates the Subcellular Localization of the Rab27a‐Binding Protein JFC1 by Phosphorylation
J. Johnson, S. Pacquelet, William Arbuthnot Sir Lane, B. Eam +1 more
2005Traffic : the International Journal of Intracellular Transport27 citations
Semantic Scholar
Myelin oligodendrocyte glycoprotein peptide-induced experimental allergic encephalomyelitis and T cell responses are unaffected by immunoproteasome deficiency.
Ricardo F. Frausto, S. Crocker, B. Eam, J. Whitmire +1 more
2007Journal of Neuroimmunology24 citations Open access
Semantic Scholar
Preclinical Evaluation of eFT226, a Novel, Potent and Selective eIF4A Inhibitor with Anti-Tumor Activity in B-Cell Malignancies
P. A. Thompson, B. Eam, N. Young, S. Fish +22 more
201711 citations
Semantic Scholar
Strategic Diastereoselective C1 Functionalization in the Aza-Rocaglamide Scaffold toward Natural Product-Inspired eIF4A Inhibitors.
C. Nilewski, Theo D. Michels, A. Xiang, Garrick K. Packard +7 more
2020Organic Letters10 citations
Semantic Scholar
1-Aminomethyl SAR in a novel series of flavagline-inspired eIF4A inhibitors: Effects of amine substitution on cell potency and in vitro PK properties.
C. Nilewski, Theo D. Michels, Garrick K. Packard, A. Xiang +10 more
2021Bioorganic & Medicinal Chemistry Letters5 citations Open access
Semantic Scholar
Abstract 2698: eFT226, a potent and selective inhibitor of eIF4A, is efficacious in preclinical models of lymphoma
P. A. Thompson, B. Eam, N. Young, S. Fish +20 more
2019Experimental and Molecular Therapeutics5 citations
Semantic Scholar
Abstract B133: eFT226, a first in class inhibitor of eIF4A1, targets FGFR1/2 and HER2 driven cancers
P. A. Thompson, N. Young, C. Stumpf, B. Eam +13 more
2019New Molecular Targets2 citations
Semantic Scholar
Fibrinolytic properties of activated factor XII
B. Eam, G. Dooijewaard, D. Rijken
19982 citations
Semantic Scholar
Dissection of cancer therapy combinations in RTK driven tumors using zotatifin (eFT226), a potent and selective eIF4A inhibitor
A. Gerson‐Gurwitz, V. Goel, N. Young, B. Eam +8 more
20201 citations
Semantic Scholar
Abstract DDT02-05: eFT226: A selective and highly potent inhibitor of eukaryotic initiation factor 4A (eIF4A), a novel approach for the treatment of cancer
S. Reich, P. A. Thompson, J. Ernst, B. Eam +22 more
2018Cancer Chemistry1 citations
Semantic Scholar
944 PK/PD ASSESSMENT OF A PHASE 1 HEALTHY VOLUNTEER STUDY WITH ANA773, AN ORAL PRODRUG OF A TLR7 AGONIST FOR THE TREATMENT OF HCV
S. Fletcher, L. Bauman, B. Eam, M. Sergeeva +5 more
20091 citations Open access
Semantic Scholar
Abstract 3399: Preclinical evaluation of eFT226, a potent and selective eIF4A inhibitor with anti-tumor activity in FGFR1,2 and HER2 driven cancers
P. A. Thompson, N. Young, A. Gerson‐Gurwitz, B. Eam +10 more
2020Tumor Biology0 citations
Semantic Scholar
Contraction following the Resolution of T Cell + Viral Antigen Prolongs CD4 Differential T Cell Responses to Residual
J. Whitton, J. Whitmire, I. Misumi, M. Alirezaei +2 more
20130 citations
Semantic Scholar
This information is current as Infection Contraction following the Resolution of T Cell + Viral Antigen Prolong CD 4 Differential T Cell Responses to Residual
I. Misumi, M. Alirezaei, B. Eam, Maureen A. Su +2 more
20130 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

P. A. Thompson×12
Invite
P. A. Thompson — researcher profile on SciRah
S. Fish×11
Invite
S. Fish — researcher profile on SciRah
J. Staunton×10
Invite
J. Staunton — researcher profile on SciRah
Gary G. Chiang×9
Invite
Gary G. Chiang — researcher profile on SciRah

×9

Invite

Joan W Chen — researcher profile on SciRah

Christopher J. Wegerski×9

Invite

Christopher J. Wegerski — researcher profile on SciRah

Invite

K. Webster — researcher profile on SciRah

Invite

N. Young — researcher profile on SciRah

Invite

S. Reich — researcher profile on SciRah

P. Sprengeler×8

Invite

P. Sprengeler — researcher profile on SciRah

Invite

J. Ernst — researcher profile on SciRah

Invite

S. Sperry — researcher profile on SciRah