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H. Deubzer · SciRah

Researcher profile · Semantic Scholar

H. Deubzer

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H. Deubzer — researcher profile on SciRah

h-index: 38
Works: 135
Citations: 5,915

Most-cited papers

Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma
R. Koche, Elias Rodriguez-Fos, K. Helmsauer, M. Burkert +34 more
2019Nature Genetics301 citations Open access
Semantic Scholar
Childhood cancer predisposition syndromes—A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology
T. Ripperger, S. Bielack, A. Borkhardt, I. Brecht +72 more
2017American Journal of Medical Genetics. Part A247 citations Open access
Semantic Scholar
Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma
H. Kocak, S. Ackermann, B. Hero, Y. Kahlert +11 more
2013Cell Death and Disease218 citations Open access
Semantic Scholar
Histone deacetylase 10 promotes autophagy-mediated cell survival
I. Oehme, Jan Linke, B. Böck, T. Milde +14 more
2013Proceedings of the National Academy of Sciences of the United States of America208 citations Open access
Semantic Scholar
Small Molecule Inhibitors of Aurora-A Induce Proteasomal Degradation of N-Myc in Childhood Neuroblastoma
Markus Brockmann, E. Poon, Teeara Berry, Anne Carstensen +10 more
2013Cancer Cell180 citations Open access
Semantic Scholar
Selective inhibition of HDAC8 decreases neuroblastoma growth in vitro and in vivo and enhances retinoic acid-mediated differentiation
I. Rettig, E. Koeneke, F. Trippel, Wc Mueller +10 more
2015Cell Death and Disease165 citations Open access
Semantic Scholar
Small Molecule Inhibitors of Aurora-A Induce Proteasomal Degradation of N-Myc in Childhood Neuroblastoma.
Markus Brockmann, E. Poon, Teeara Berry, Anne Carstensen +10 more
2016Cancer Cell139 citations Open access
Semantic Scholar
HD-MB03 is a novel Group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment
T. Milde, M. Lodrini, L. Savelyeva, A. Korshunov +9 more
2012Journal of Neuro-Oncology126 citations
Semantic Scholar
HDAC11 is a novel drug target in carcinomas
H. Deubzer, M. C. Schier, I. Oehme, M. Lodrini +3 more
2013International Journal of Cancer115 citations
Semantic Scholar
2017 GPOH Guidelines for Diagnosis and Treatment of Patients with Neuroblastic Tumors
T. Simon, B. Hero, J. Schulte, H. Deubzer +14 more
2017Klinische Pädiatrie110 citations
Semantic Scholar
MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma
M. Lodrini, I. Oehme, C. Schroeder, T. Milde +12 more
2013Nucleic Acids Research98 citations Open access
Semantic Scholar
Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions
Karin Schmelz, J. Toedling, Matthew R. Huska, Maja C. Cwikla +21 more
2021Nature Communications92 citations Open access
Semantic Scholar
Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells
Rocío Chamorro González, Thomas Conrad, Maja C. Stöber, Robin Xu +22 more
2023Nature Genetics82 citations Open access
Semantic Scholar
Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma
J. Ecker, I. Oehme, Ralph Mazitschek, A. Korshunov +12 more
2015Acta Neuropathologica Communications79 citations Open access
Semantic Scholar
Using droplet digital PCR to analyze MYCN and ALK copy number in plasma from patients with neuroblastoma
M. Lodrini, A. Sprüssel, K. Astrahantseff, Daniela Tiburtius +6 more
2017OncoTarget73 citations Open access
Semantic Scholar
Reactivating TP53 signaling by the novel MDM2 inhibitor DS-3032b as a therapeutic option for high-risk neuroblastoma
Viktor Arnhold, Karin Schmelz, Jutta Proba, A. Winkler +7 more
2017OncoTarget70 citations Open access
Semantic Scholar
Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma.
L. Moreno, G. Barone, S. DuBois, J. Molenaar +34 more
2020European Journal of Cancer64 citations Open access
Semantic Scholar
Neuroblastoma cells depend on HDAC11 for mitotic cell cycle progression and survival
Theresa M. Thole, M. Lodrini, J. Fabian, Jasmin Wuenschel +9 more
2017Cell Death and Disease61 citations Open access
Semantic Scholar
GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3.
J. Fabian, M. Lodrini, I. Oehme, M. C. Schier +18 more
2014Cancer Research57 citations
Semantic Scholar
The pitfalls and promise of liquid biopsies for diagnosing and treating solid tumors in children: a review
R. van Paemel, R. Vlug, K. De Preter, N. Van Roy +9 more
2020European Journal of Pediatrics55 citations Open access
Semantic Scholar
Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas.
A. Künkele, K. De Preter, L. Heukamp, T. Thor +9 more
2012Neuro-Oncology55 citations Open access
Semantic Scholar
Mutations in ALK signaling pathways conferring resistance to ALK inhibitor treatment lead to collateral vulnerabilities in neuroblastoma cells
Mareike Berlak, E. Tucker, Mathurin Dorel, A. Winkler +32 more
2022Molecular Cancer54 citations Open access
Semantic Scholar
A Reproducible Bioprinted 3D Tumor Model Serves as a Preselection Tool for CAR T Cell Therapy Optimization
Laura Grunewald, Tobias Lam, Lena Andersch, Anika Klaus +14 more
2021Frontiers in Immunology49 citations Open access
Semantic Scholar
Nestin Expression Identifies Ependymoma Patients with Poor Outcome
T. Milde, T. Hielscher, H. Witt, M. Kool +11 more
2012Brain Pathology47 citations Open access
Semantic Scholar
The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models
Kristian W. Pajtler, Natalie Sadowski, S. Ackermann, K. Althoff +15 more
2016OncoTarget42 citations Open access
Semantic Scholar
Targeted analysis of cell-free circulating tumor DNA is suitable for early relapse and actionable target detection in patients with neuroblastoma.
M. Lodrini, Josefine Graef, T. Thole-Kliesch, K. Astrahantseff +17 more
2022Clinical Cancer Research41 citations Open access
Semantic Scholar
Tumor-Derived Extracellular Vesicles Impair CD171-Specific CD4+ CAR T Cell Efficacy
Solin Ali, K. Toews, Silke Schwiebert, Anika Klaus +13 more
2020Frontiers in Immunology36 citations Open access
Semantic Scholar
MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma
J. Fabian, Desirée Opitz, K. Althoff, M. Lodrini +36 more
2016OncoTarget36 citations Open access
Semantic Scholar
Bioprinting of Perfusable Vascularized Organ Models for Drug Development via Sacrificial‐Free Direct Ink Writing
Dong-Liang Wu, Shu-Min Pang, Johanna Berg, Yikun Mei +8 more
2024Advanced Functional Materials31 citations Open access
Semantic Scholar
Incidence of subsequent malignancies after total body irradiation-based allogeneic HSCT in children with ALL – long-term follow-up from the prospective ALL-SCT 2003 trial
A. Eichinger, U. Poetschger, E. Glogova, P. Bader +24 more
2022Leukemia28 citations Open access
Semantic Scholar
Bioprinted Cancer Model of Neuroblastoma in a Renal Microenvironment as an Efficiently Applicable Drug Testing Platform
Dong-Liang Wu, J. Berg, Birte Arlt, Viola Röhrs +3 more
2021International Journal of Molecular Sciences28 citations Open access
Semantic Scholar
Circulating Cell-Free DNA Assessment in Biofluids from Children with Neuroblastoma Demonstrates Feasibility and Potential for Minimally Invasive Molecular Diagnostics
M. Lodrini, J. Wünschel, T. Thole-Kliesch, Maddalena Grimaldi +13 more
2022Cancers27 citations Open access
Semantic Scholar
Inhibiting phosphoglycerate dehydrogenase counteracts chemotherapeutic efficacy against MYCN‐amplified neuroblastoma
Birte Arlt, Christin Zasada, Katharina Baum, Jasmin Wuenschel +14 more
2020International Journal of Cancer24 citations Open access
Semantic Scholar
Synergistic activity of BET inhibitor MK-8628 and PLK inhibitor Volasertib in preclinical models of medulloblastoma.
You-Jia Han, S. Lindner, Yi Bei, H. García +10 more
2019Cancer Letters23 citations
Semantic Scholar
Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN
Steffen Fuchs, C. Danssmann, F. Klironomos, A. Winkler +26 more
2023Nature Communications19 citations Open access
Semantic Scholar
Multiplexed quantification of four neuroblastoma DNA targets in a single droplet digital PCR reaction.
Constantin Peitz, A. Sprüssel, Rasmus B. Linke, K. Astrahantseff +11 more
2020Journal of Molecular Diagnostics19 citations Open access
Semantic Scholar
Central memory phenotype drives success of checkpoint inhibition in combination with CAR T cells
K. Toews, Laura Grunewald, Silke Schwiebert, Anika Klaus +11 more
2020Molecular Carcinogenesis18 citations Open access
Semantic Scholar
Phase I/II Intra-patient Dose Escalation Study of Vorinostat in Children with Relapsed Solid Tumor, Lymphoma or Leukemia
O. Witt, T. Milde, H. Deubzer, I. Oehme +5 more
2012Klinische Pädiatrie16 citations Open access
Semantic Scholar
Inhibiting PHGDH with NCT-503 reroutes glucose-derived carbons into the TCA cycle, independently of its on-target effect
Birte Arlt, G. Mastrobuoni, Jasmin Wuenschel, K. Astrahantseff +3 more
2021Journal of Enzyme Inhibition and Medicinal Chemistry15 citations Open access
Semantic Scholar
Reflection of neuroblastoma intratumor heterogeneity in the new OHC‐NB1 disease model
Theresa M. Thole, J. Toedling, A. Sprüssel, Sebastian Pfeil +17 more
2020International Journal of Cancer13 citations Open access
Semantic Scholar
GPOH Guidelines for Diagnosis and First-line Treatment of Patients with Neuroblastic Tumors, update 2025
T. Simon, Theresa M. Thole, Sveva Castelli, B. Timmermann +20 more
2025Klinische Pädiatrie12 citations
Semantic Scholar
Rituximab therapy after pediatric hematopoietic stem cell transplantation can cause prolonged B-cell impairment and increases the risk for infections - a retrospective matched cohort study
M. Launspach, Dennis Temel, Emily Ohlendorf, F. Zirngibl +12 more
2022Haematologica10 citations Open access
Semantic Scholar
Neuroblastoma Risk Assessment and Treatment Stratification with Hybrid Capture-Based Panel Sequencing
A. Szymansky, Louisa-Marie Kruetzfeldt, L. Heukamp, F. Hertwig +17 more
2021Journal of Personalized Medicine10 citations Open access
Semantic Scholar
Publisher Correction: Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma
R. Koche, Elias Rodriguez-Fos, K. Helmsauer, M. Burkert +34 more
2020Nature Genetics10 citations Open access
Semantic Scholar
Treatment of Infants and Children With SARS-CoV-2 Monoclonal Antibodies: A European Case Series
Cornelius Rau, L. Auer-Hackenberg, H. Deubzer, Elisabeth Schwabel +17 more
2022The Pediatric Infectious Disease Journal9 citations Open access
Semantic Scholar
Evidence of neural crest cell origin of a DICER1 mutant CNS sarcoma in a child with DICER1 syndrome and NRAS‐mutant neurocutaneous melanosis
L. Schweizer, W. Hartmann, A. Koch, Maximilian Nunninger +12 more
2022Neuropathology and Applied Neurobiology9 citations Open access
Semantic Scholar
Management of malignant dysgerminoma of the ovary
Tjadina Arndt, E. Taube, H. Deubzer, K. Rothe +3 more
2022European Journal of Gynaecological Oncology9 citations Open access
Semantic Scholar
Minichromosome Maintenance Complex Is a Critical Node in the miR-183 Signaling Network of MYCN-Amplified Neuroblastoma Cells.
M. Lodrini, G. Poschmann, V. Schmidt, J. Wünschel +7 more
2016Journal of Proteome Research9 citations
Semantic Scholar
Current treatment strategies for first relapse of high-risk neuroblastoma.
Sveva Castelli, F. Schulze, T. Thole-Kliesch, K. Astrahantseff +25 more
2026European Journal of Cancer8 citations Open access
Semantic Scholar
Management of Busulfan-Induced Lung Injury in Pediatric Patients with High-Risk Neuroblastoma
Sveva Castelli, Anne Thorwarth, Claudia van Schewick, Anke Wendt +8 more
2024Journal of Clinical Medicine7 citations Open access
Semantic Scholar

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