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L. Tan · SciRah

Researcher profile · Semantic Scholar

L. Tan

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L. Tan — researcher profile on SciRah

h-index: 27
Works: 63
Citations: 3,365

Most-cited papers

KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase
Yugang Wang, Yu-Song R. Guo, Ke Liu, Z. Yin +14 more
2017Nature512 citations Open access
Semantic Scholar
CD38-mediated immunosuppression as a mechanism of tumor cell escape from PD-1/PD-L1 blockade
Limo Chen, L. Diao, Yong-Bing Yang, X. Yi +35 more
2018Cancer Discovery407 citations Open access
Semantic Scholar
Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers
Xin-Xin Peng, Zhong-Yuan Chen, F. Farshidfar, Xiao-Yan Xu +17 more
2018Cell Reports273 citations Open access
Semantic Scholar
PTEN Suppresses Glycolysis by Dephosphorylating and Inhibiting Autophosphorylated PGK1.
Xu Qian, Xinjian Li, Zhumei Shi, Yan Xia +13 more
2019Molecules and Cells189 citations Open access
Semantic Scholar
EGFR-Phosphorylated Platelet Isoform of Phosphofructokinase 1 Promotes PI3K Activation
Jong-Ho Lee, Rui Liu, Jing Li, Yugang Wang +15 more
2018Molecules and Cells183 citations Open access
Semantic Scholar
Genome-wide identification and differential analysis of translational initiation
Peng Zhang, Dan-Dan He, Yi Xu, Jiakai Hou +15 more
2017Nature Communications150 citations Open access
Semantic Scholar
The glutaminase inhibitor CB-839 (Telaglenastat) enhances the anti-melanoma activity of T cell mediated immunotherapies.
Sruthy Varghese, Snigdha Pramanik, Leila J. Williams, Hannah R Hodges +12 more
2020Molecular Cancer Therapeutics136 citations Open access
Semantic Scholar
Choline kinase alpha 2 acts as a protein kinase to promote lipolysis of lipid droplets.
R. Liu, Jong-Ho Lee, Jingyi Li, Rilei Yu +7 more
2021Molecules and Cells132 citations Open access
Semantic Scholar
ElemCor: accurate data analysis and enrichment calculation for high-resolution LC-MS stable isotope labeling experiments
Di Du, L. Tan, Yu-Meng Wang, Bo Peng +4 more
2019BMC Bioinformatics110 citations Open access
Semantic Scholar
ATF4 Protects the Heart from Failure by Antagonizing Oxidative Stress
Xiao-Ding Wang, Guangyu Zhang, Subhajit Dasgupta, Erica L. Niewold +12 more
2022Circulation Research108 citations Open access
Semantic Scholar
Targeting MCL-1 dysregulates cell metabolism and leukemia-stroma interactions and re-sensitizes acute myeloid leukemia to BCL-2 inhibition
B. Carter, P. Mak, Wen-Jing Tao, M. Warmoes +7 more
2020Haematologica108 citations Open access
Semantic Scholar
Mucus-degrading Bacteroides link carbapenems to aggravated graft-versushost disease
Eiko Hayase, Tomoyoshi Hayase, M. Jamal, T. Miyama +36 more
2022Cell89 citations Open access
Semantic Scholar
A sucrose-enriched diet promotes tumorigenesis in mammary gland in part through the 12-lipoxygenase pathway
Yan Jiang, Yong Pan, P. Rhea, L. Tan +4 more
2016Cancer Research83 citations Open access
Semantic Scholar
Conversion of PRPS hexamer to monomer by AMPK-mediated phosphorylation inhibits nucleotide synthesis in response to energy stress
Xu Qian, Xinjian Li, L. Tan, Jong-Ho Lee +6 more
2017Cancer Discovery78 citations Open access
Semantic Scholar
Mitochondrial structure and function adaptation in residual triple negative breast cancer cells surviving chemotherapy treatment
Mokryun L. Baek, June-Chul Lee, K. Pendleton, Mariah J. Berner +11 more
2022bioRxiv76 citations Open access
Semantic Scholar
Glutaminase activity of L-asparaginase contributes to durable preclinical activity against acute lymphoblastic leukemia
Wai-Kin Chan, Thomas D. Horvath, L. Tan, T. Link +11 more
2019Molecular Cancer Therapeutics64 citations Open access
Semantic Scholar
PKM1 Exerts Critical Roles in Cardiac Remodeling under Pressure Overload in the Heart
Qin-Feng Li, Chao Li, Abdallah Elnwasany, Gaurav Sharma +25 more
2021Circulation57 citations Open access
Semantic Scholar
Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment
Zaker I. Schwabkey, Diana H. Wiesnoski, Chia-Chi Chang, Wen-Bin Tsai +55 more
2021bioRxiv54 citations Open access
Semantic Scholar
Medium-chain acyl CoA dehydrogenase protects mitochondria from lipid peroxidation in glioblastoma
F. Puca, Fei Yu, C. Bartolacci, P. Pettazzoni +25 more
2021Cancer Discovery47 citations Open access
Semantic Scholar
PBI-05204, a supercritical CO2 extract of Nerium oleander, inhibits growth of human pancreatic cancer via targeting the PI3K/mTOR pathway
Yong Pan, P. Rhea, L. Tan, C. Cartwright +8 more
2014Investigational new drugs41 citations Open access
Semantic Scholar
The bacterial microbiota regulates normal hematopoiesis via metabolite-induced type 1 interferon signaling
Hannah H. Yan, Forrest C. Walker, Arushana Ali, Hyojeong Han +5 more
2022Blood Advances39 citations Open access
Semantic Scholar
Changes in Cancer Cell Metabolism Revealed by Direct Sample Analysis with MALDI Mass Spectrometry
David A. Pirman, E. Efuet, Xiao-Ping Ding, Yong Pan +4 more
2013PLoS ONE39 citations Open access
Semantic Scholar
Lipidomic Profiles of Plasma Exosomes Identify Candidate Biomarkers for Early Detection of Hepatocellular Carcinoma in Patients with Cirrhosis
Jessica I. Sanchez, Jing-Jing Jiao, Suet-Ying Kwan, Lucas Veillon +8 more
2021Cancer Prevention Research38 citations Open access
Semantic Scholar
Eicosapentaenoic acid in combination with EPHA2 inhibition shows efficacy in preclinical models of triple-negative breast cancer by disrupting cellular cholesterol efflux
Angie M. Torres-Adorno, H. Vitrac, Yuan Qi, L. Tan +6 more
2018Oncogene36 citations Open access
Semantic Scholar
USP21 deubiquitinase elevates macropinocytosis to enable oncogenic KRAS bypass in pancreatic cancer
Ping-Ping Hou, Xingdi Ma, Ze-Cheng Yang, Qiang Zhang +13 more
2021Genes & Development35 citations Open access
Semantic Scholar
Adipose tissue–specific ablation of Ces1d causes metabolic dysregulation in mice
Gang Li, Xin Li, Li Yang, Shuyue Wang +10 more
2022Life Science Alliance29 citations Open access
Semantic Scholar
Suppression of Membranous LRP5 Recycling, Wnt/β-catenin Signaling, and Colon Carcinogenesis by 15-LOX-1 Peroxidation of Linoleic Acid in PI3P
Fuyao Liu, Xiang-Sheng Zuo, Yi Liu, Yasunori Deguchi +12 more
2020Cell Reports28 citations Open access
Semantic Scholar
PGC1α is required for the renoprotective effect of lncRNA Tug1 in vivo and links Tug1 with urea cycle metabolites
Li Li, J. Long, K. Mise, Daniel L. Galvan +7 more
2021Cell Reports26 citations Open access
Semantic Scholar
Deletion of cyclooxygenase-2 inhibits K-ras–induced lung carcinogenesis
Yong Pan, Yan Jiang, L. Tan, Murali K. Ravoori +4 more
2015OncoTarget23 citations Open access
Semantic Scholar
Assessment of l-Asparaginase Pharmacodynamics in Mouse Models of Cancer
Thomas D. Horvath, Wai-Kin Chan, Michael A. Pontikos, L. A. Martin +5 more
2019Metabolites22 citations Open access
Semantic Scholar
Regulation of growth, invasion and metabolism of breast ductal carcinoma through CCL2/CCR2 signaling interactions with MET receptor tyrosine kinases
D. Acevedo, W. Fang, Vinamratha Rao, Vedha Penmetcha +8 more
2022Neoplasia20 citations Open access
Semantic Scholar
The transcription factor ChREBP links mitochondrial lipidomes to mitochondrial morphology and progression of diabetic kidney disease
Li Li, J. Long, K. Mise, Naravat Poungavrin +7 more
2023Journal of Biological Chemistry19 citations Open access
Semantic Scholar
Development of a rational strategy for integration of lactate dehydrogenase A suppression into therapeutic algorithms for head and neck cancer
Yun-Yun Chen, A. Maniakas, L. Tan, M. Cui +12 more
2021British Journal of Cancer18 citations Open access
Semantic Scholar
Combined inhibition of HMGCoA reductase and mitochondrial complex I induces tumor regression of BRAF inhibitor-resistant melanomas
Evelyn L. de Groot, Sruthy Varghese, L. Tan, Barbara G. Knighton +8 more
2022Cancer & Metabolism16 citations Open access
Semantic Scholar
Activation of Vitamin D/VDR Signaling Reverses Gemcitabine Resistance of Pancreatic Cancer Cells Through Inhibition of MUC1 Expression
D. Wei, Liang Wang, Yi Liu, Margarete Hafley +5 more
2023Digestive Diseases and Sciences15 citations Open access
Semantic Scholar
Pathogenesis of Tobacco-Associated Lung Adenocarcinoma Is Closely Coupled with Changes in the Gut and Lung Microbiomes
Casey T. Finnicum, Zahraa Rahal, M. Hassane, W. Treekitkarnmongkol +13 more
2022International Journal of Molecular Sciences11 citations Open access
Semantic Scholar
Targeting Glutamine Metabolism with a Novel Na+/K+-ATPase Inhibitor RX108 in Hepatocellular Carcinoma
D. Wei, Dong-Mei Chen, Hongyuan Mou, Sharmistha Chakraborty +5 more
2023Molecular Cancer Therapeutics10 citations Open access
Semantic Scholar
Compound NSC84167 selectively targets NRF2-activated pancreatic cancer by inhibiting asparagine synthesis pathway
Bing-Bing Dai, J. Augustine, Ya'an Kang, D. Roife +8 more
2021Cell Death and Disease10 citations Open access
Semantic Scholar
Vitamin B2 enables regulation of fasting glucose availability
Peter M. Masschelin, P. Saha, S. Ochsner, A. Cox +17 more
2023eLife9 citations Open access
Semantic Scholar
Mass spectrometry-based stable-isotope tracing uncovers metabolic alterations in pyruvate kinase-deficient Aedes aegypti mosquitoes
N. Petchampai, J. Isoe, Thomas D. Horvath, Shai Dagan +4 more
2020Insect Biochemistry and Molecular Biology9 citations Open access
Semantic Scholar
Vincristine Enhances the Efficacy of MEK Inhibitors in Preclinical Models of KRAS-mutant Colorectal Cancer
Susmita Ghosh, F. Fan, R. Powell, J. Roszik +9 more
2023Molecular Cancer Therapeutics6 citations Open access
Semantic Scholar
Noncanonical role of singleminded-2s in mitochondrial respiratory chain formation in breast cancer
Steven W. Wall, L. Sanchez, Kelly Tuttle, Scott J. Pearson +10 more
2023Experimental and Molecular Medicine6 citations Open access
Semantic Scholar
The Glutaminase Activity of L-Asparaginase Mediates Suppression of Asns Upregulation
Wai-Kin Chan, L. Tan, Karine Harutyunyan, Di Du +5 more
2018Blood5 citations Open access
Semantic Scholar
Response envelope analysis for quantitative evaluation of drug combinations
Di Du, Chia-Hua Chang, Yu-Meng Wang, P. Tong +6 more
2019Bioinform.3 citations Open access
Semantic Scholar
Abstract 3206: Mistletoe extract inhibits the proliferation of human hepatocellular carcinoma cells by induction of apoptosis and downregulation of c-MYC
Xiao-Ping Ding, C. Cartwright, L. Tan, Richard T. Lee +1 more
20143 citations
Semantic Scholar
Oncometabolism Drives Autophagy Activation in Skeletal Muscle
Anja Karlstaedt, H. Vitrac, Rebecca L. Salazar, Benjamin D. Gould +16 more
2020bioRxiv2 citations Open access
Semantic Scholar
Inhibition of Anti-Apoptotic Mcl-1 Exerts Anti-Leukemia Activity through Modulation of Leukemia-Stromal Interactions and Metabolic Functions in AML
B. Carter, P. Mak, M. Warmoes, Wen-Jing Tao +6 more
2019Blood2 citations Open access
Semantic Scholar
Abstract 158: Sustained adrenergic signaling activates pro-inflammatory networks in ovarian carcinoma
A. Nagaraja, G. Armaiz-Peña, Julie K. Allen, Nouara C. Sadaoui +6 more
20141 citations
Semantic Scholar
Abstract P6-11-15: Lipid accumulation in residual triple negative breast cancer cells surviving chemotherapy treatment
K. Pendleton, Mokryun L. Baek, J. Lee, L. Tan +7 more
2023Cancer Research0 citations
Semantic Scholar
Targeting DNA2 Overcomes Metabolic Reprogramming in 1q21 Multiple Myeloma
N. Thongon, Fei-Yang Ma, M. Marchesini, Jin-Tan Liu +24 more
2022Leading Edge of Cancer Research Symposium: Poster Session0 citations Open access
Semantic Scholar

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