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Jane Cheng · SciRah

Researcher profile · Semantic Scholar

Jane Cheng

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Jane Cheng — researcher profile on SciRah

h-index: 12
Works: 29
Citations: 2,777

Most-cited papers

Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974
Jun Liu, Shifeng Pan, Mindy H. Hsieh, Nicholas Ng +32 more
2013Proceedings of the National Academy of Sciences of the United States of America821 citations Open access
Semantic Scholar
Heart transplantation in baboons using α1,3-galactosyltransferase gene-knockout pigs as donors: initial experience
K. Kuwaki, Yau-Lin Tseng, F. Dor, A. Shimizu +18 more
2005Nature Medicine719 citations
Semantic Scholar
Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primates
B. Hering, M. Wijkstrom, M. Graham, M. Hårdstedt +15 more
2006Nature Medicine550 citations
Semantic Scholar
Suppression of Natural and Elicited Antibodies in Pig‐to‐Baboon Heart Transplantation Using a Human Anti‐Human CD154 mAb‐Based Regimen
K. Kuwaki, C. Knosalla, F. Dor, B. Gollackner +13 more
2004American Journal of Transplantation145 citations Open access
Semantic Scholar
Thrombotic microangiopathy and graft arteriopathy in pig hearts following transplantation into baboons
S. Houser, K. Kuwaki, C. Knosalla, F. Dor +5 more
2004Xenotransplantation138 citations
Semantic Scholar
Pathology of xenograft rejection: a commentary
H. Schuurman, Jane Cheng, Tuan T. Lam
2003Xenotransplantation98 citations
Semantic Scholar
&agr;1,3-Galactosyltransferase Gene-Knockout Miniature Swine Produce Natural Cytotoxic Anti-Gal Antibodies
F. Dor, Yau-Lin Tseng, Jane Cheng, K. Moran +9 more
2004Transplantation82 citations Open access
Semantic Scholar
Elimination of Porcine Hemopoietic Cells by Macrophages in Mice1
M. Abe, Jane Cheng, J. Qi, R. Glaser +3 more
2002Journal of Immunology62 citations Open access
Semantic Scholar
Galα1,3Gal expression on porcine pancreatic islets, testis, spleen, and thymus
F. Dor, Jane Cheng, A. Alt, D. K. C. Cooper +1 more
200457 citations
Semantic Scholar
SAR439859, a Novel Selective Estrogen Receptor Degrader (SERD), Demonstrates Effective and Broad Antitumor Activity in Wild-Type and Mutant ER-Positive Breast Cancer Models
Maysoun Shomali, Jane Cheng, Fangxian Sun, M. Koundinya +26 more
2020Molecular Cancer Therapeutics44 citations Open access
Semantic Scholar
LBY135, a novel anti‐DR5 agonistic antibody induces tumor cell–specific cytotoxic activity in human colon tumor cell lines and xenografts
Jing Li, D. Knee, Youzhen Wang, Qingxiu Zhang +13 more
200822 citations
Semantic Scholar
Validation of a predictive modeling approach to demonstrate the relative efficacy of three different schedules of the AKT inhibitor AZD5363
J. Yates, P. Dudley, Jane Cheng, C. D'Cruz +1 more
2015Cancer Chemotherapy and Pharmacology15 citations
Semantic Scholar
Abstract 943: SAR439859, an orally bioavailable selective estrogen receptor degrader (SERD) that demonstrates robust antitumor efficacy and limited cross-resistance in ER+ breast cancer
M. Bouaboula, Maysoun Shomali, Jane Cheng, N. Malkova +23 more
2018Endocrinology7 citations
Semantic Scholar
T Cells from Presensitized Donors Fail to Cause Graft-versus-Host Disease in a Pig-to-Mouse Xenotransplantation Model
H. Eguchi, C. Knosalla, P. Lan, Jane Cheng +8 more
2004Transplantation6 citations Open access
Semantic Scholar
Abstract 919: AZD3463, a novel ALK/IGF1R inhibitor, overcomes multiple mechanisms of acquired resistance to crizotinib.
L. Drew, Jane Cheng, J. Engelman, Douglas Ferguson +8 more
20135 citations
Semantic Scholar
Potent anticancer activity of the deacetylase inhibitor panobinostat (LBH589) in colon cancer cell lines and patient-derived primary colon cancer xenografts
Youzhen Wang, J. Growney, Jane Cheng, C. Kowal +11 more
20083 citations
Semantic Scholar
Efficacy of Panobinostat (LBH589) in Multiple Myeloma Cell Lines and In Vivo Mouse Model: Tumor-Specific Cytotoxicity and Protection of Bone Integrity in Multiple Myeloma.
J. Growney, P. Atadja, W. Shao, Youzhen Wang +11 more
20073 citations
Semantic Scholar
Abstract P4-02-08: Amcenestrant in combination with CDK4/6 inhibitor palbociclib demonstrates synergistic anti-tumor activity in ER+ endocrine-resistant breast cancer xenograft models
Maysoun Shomali, Zhuyan Guo, Jane Cheng, A. Sullivan +9 more
2022Cancer Research1 citations
Semantic Scholar
Abstract 6033: RA123, a new GLS1 allosteric inhibitor demonstrates in vitro and in vivo activity in multiple myeloma models
Christophe Henry, Dimitri Gorge-Bernat, Pascal Pannier, I. Meaux +11 more
2023Cancer Research0 citations
Semantic Scholar
Abstract 5590: Inhibition of the autophagy protein Vps34 induces tumor cell secretion of proinflammatory chemokines
M. Bernardo, Yu-An Zhang, Martin Graf, Jane Cheng +8 more
2022Cancer Research0 citations
Semantic Scholar
MOLECULAR CANCER THERAPEUTICS | SMALL MOLECULE THERAPEUTICS SAR439859, a Novel Selective Estrogen Receptor Degrader (SERD), Demonstrates Effective and Broad Antitumor Activity in Wild-Type and Mutant ER-Positive Breast Cancer Models
Maysoun Shomali, Jane Cheng, Fangxian Sun, M. Koundinya +26 more
20200 citations
Semantic Scholar
Abstract 3452: Pre-clinical development of next generation selective estrogen receptor degrader - SAR439859
Fangxian Sun, Jane Cheng, A. Sullivan, N. Malkova +8 more
2020Clinical research0 citations
Semantic Scholar
Abstract 1377: Identification and validation of WRN as a novel synthetic lethality target in context of microsatellite instability
Z. Ding, Jing Zhang, C. Pedamallu, S. Rowley +19 more
2020Molecular and Cellular Biology / Genetics0 citations
Semantic Scholar
Abstract 5775: Identification of SAR439859, an orally bioavailable selective estrogen receptor degrader (SERD) that has strong anti-tumor activity in wild-type and mutant ER+ breast cancer models
Maysoun Shomali, Y. El-Ahmad, F. Halley, Jane Cheng +35 more
2018Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Abstract 3362: Miniaturized PBPK model improves pharmacodynamic characterization and physiological interpretability for compounds with profound hysteresis in tumor.
F. Gibbons, D. Widzowski, Minhui Shen, Jane Cheng +3 more
20130 citations
Semantic Scholar
Abstract 2461: Design and synthesis of AZD3463, a novel orally bioavailable dual ALK and IGF1R inhibitor, inhibits growth of crizotinib resistance cell lines with multiple mechanisms of acquired resistance.
J. Saeh, Bin Yang, Timothy W Pontz, Kumar D Thakur +14 more
20130 citations
Semantic Scholar
Monoclonal antibody lead characterization: in vitro and in vivo methods.
Axel Hernandez, J. Parmentier, Youzhen Wang, Jane Cheng +1 more
2012Methods in molecular biology0 citations
Semantic Scholar
This information is current as Macrophages in Mice Elimination of Porcine Hemopoietic Cells
Masahiro Abe, Jane Cheng, J. Qi, R. Glaser +3 more
20010 citations
Semantic Scholar
MACROPHAGE DEPLETION PROMOTES XENOGENEIC HEMATOPOIETIC CHIMERISM
Jane Cheng, R. Glaser, D. Cooper, M. White-Scharf +1 more
19990 citations Open access
Semantic Scholar

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Fangxian Sun×10
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H. Schuurman×8
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