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I. Meaux · SciRah

Researcher profile · Semantic Scholar

I. Meaux

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I. Meaux — researcher profile on SciRah

h-index: 3
Works: 15
Citations: 401

Most-cited papers

SAR405838: An optimized inhibitor of MDM2-p53 interaction that induces complete and durable tumor regression
Shaomeng Wang, Wei Sun, Yu-Jun Zhao, D. McEachern +18 more
2014Cancer Research265 citations Open access
Semantic Scholar
SAR405838: A novel and potent inhibitor of the MDM2:p53 axis for the treatment of dedifferentiated liposarcoma
K. Bill, J. Garnett, I. Meaux, Xiao-yi Ma +13 more
2015Clinical Cancer Research96 citations Open access
Semantic Scholar
Efficacy of the MDM2 inhibitor SAR405838 in glioblastoma is limited by poor distribution across the blood-brain barrier
Minjee Kim, D. Ma, David Calligaris, Shuangling Zhang +19 more
2018Molecular Cancer Therapeutics31 citations Open access
Semantic Scholar
Correction: SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma
K. Bill, J. Garnett, I. Meaux, Xiao-yi Ma +13 more
2022Clinical Cancer Research3 citations Open access
Semantic Scholar
Abstract LB-204: Highly potent and optimized small-molecule inhibitors of MDM2 achieve complete tumor regression in animal models of solid tumors and leukemia.
Shaomeng Wang, Wei Sun, Shang-Hai Yu, Yu-Jun Zhao +27 more
20113 citations
Semantic Scholar
Abstract 4648: In vitro characterization of spiro-oxindole-based modulators of the MDM2-p53 interaction and their interspecies selectivity.
C. Delaisi, I. Meaux, Odette Dos-Santos, C. Barrière +25 more
20122 citations
Semantic Scholar
Abstract 805: Disruption of the MDM2-p53 interaction synergizes with MEK inhibition to induce cell death and promote tumor regression in p53 wild-type, Ras or Raf-mutant tumor models
I. Meaux, J. Nicolas, S. Rowley, S. Sidhu +8 more
20141 citations
Semantic Scholar
XPR1, key regulator of phosphate homeostasis and potential drug target for ovarian and lung cancer
Pascal Pannier, A. Lebsir, V. Ogor, E. Calvet +10 more
2026BMC Cancer0 citations Open access
Semantic Scholar
421 (PB409): XPR1, key regulator of phosphate homeostasis is a potential drug target for ovarian and lung cancer
P. Pannier, A. Kumar, A. Lebsir, V. Ogor +9 more
2024European Journal of Cancer0 citations
Semantic Scholar
Abstract 6033: RA123, a new GLS1 allosteric inhibitor demonstrates in vitro and in vivo activity in multiple myeloma models
Christophe Henry, Dimitri Gorge-Bernat, Pascal Pannier, I. Meaux +11 more
2023Cancer Research0 citations
Semantic Scholar
Abstract 2125: Roles of KAT6A and KAT6B in the biology of estrogen positive breast cancer
I. Meaux, Dimitri Gorge-Bernat, Angèle Paz, Catherine Geslin +3 more
2021Molecular and Cellular Biology/Genetics0 citations
Semantic Scholar
Abstract 242: Identification of biomarkers predicting sensitivity to GLS1 inhibition using a CRISPR screen
Christophe Henry, K. Berthelot, C. Lanneau, C. Orsini +7 more
2020Molecular and Cellular Biology / Genetics0 citations
Semantic Scholar
Abstract 3070: Discovery of novel potent allele-selective KRAS-G12C covalent inhibitors stemming from DNA-encoded library
G. Mccort, R. Arrebola, L. Calvet, B. Ronan +21 more
2019Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Abstract 1799: Targeted murine double minute 2 (MDM2) inhibition results in dramatic tumor regression in an MDM2-amplified glioblastoma multiforme (GBM) xenograft model
A. Mladek, I. Meaux, K. Bakken, Pascal Pannier +4 more
20140 citations
Semantic Scholar
Abstract 4731: Cytotoxic versus cytostatic effects in tumor models by spiro-oxindole-based modulators of the MDM2-p53 interaction
I. Meaux, C. Barrière, D. McEachern, S. Guérif +15 more
20120 citations
Semantic Scholar

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