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Christine Esau · SciRah

Researcher profile · Semantic Scholar

Christine Esau

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Christine Esau — researcher profile on SciRah

h-index: 31
Works: 54
Citations: 11K

Most-cited papers

miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting.
Christine Esau, Scott Davis, S. Murray, Xing Xian Yu +13 more
2006Cell Metabolism2,143 citations Open access
Semantic Scholar
MicroRNA-143 Regulates Adipocyte Differentiation*
Christine Esau, Xiao-Lin Kang, Eigen Peralta, Elaine M. Hanson +11 more
2004Journal of Biological Chemistry1,035 citations Open access
Semantic Scholar
MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators
G. Gabriely, T. Wurdinger, S. Kesari, Christine Esau +3 more
2008Molecular and Cellular Biology934 citations Open access
Semantic Scholar
Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis.
Katey J. Rayner, Frederick J. Sheedy, Christine Esau, F. Hussain +9 more
2011Journal of Clinical Investigation733 citations Open access
Semantic Scholar
Inhibition of miR-33a/b in non-human primates raises plasma HDL and reduces VLDL triglycerides
Katey J. Rayner, Christine Esau, F. Hussain, Allison L. Mcdaniel +13 more
2011Nature449 citations Open access
Semantic Scholar
Improved targeting of miRNA with antisense oligonucleotides
Scott Davis, B. Lollo, S. Freier, Christine Esau
2006Nucleic Acids Research426 citations Open access
Semantic Scholar
Integration of microRNA miR-122 in hepatic circadian gene expression.
D. Gatfield, G. le Martelot, C. Vejnar, D. Gerlach +7 more
2009Genes & Development398 citations Open access
Semantic Scholar
Inhibition of miR-33 a / b in non-human primates raises plasma HDL and reduces VLDL triglycerides
Katey J. Rayner, Christine Esau, F. Hussain, Allison L. Mcdaniel +19 more
2011397 citations
Semantic Scholar
Neuronal Exosomal miRNA-dependent Translational Regulation of Astroglial Glutamate Transporter GLT1*
Lydie J. Morel, M. R. Regan, Haruki Higashimori, Seng Kah Ng +4 more
2013Journal of Biological Chemistry376 citations Open access
Semantic Scholar
Enhanced B-1 cell development, but impaired IgG antibody responses in mice deficient in secreted IgM.
M. Boes, Christine Esau, Michael B. Fischer, T. Schmidt +2 more
1998Journal of Immunology357 citations
Semantic Scholar
Development of a micro-array to detect human and mouse microRNAs and characterization of expression in human organs.
Ying-Qing Sun, S. Koo, Neill R. White, Eigen Peralta +3 more
2004Nucleic Acids Research346 citations Open access
Semantic Scholar
Human Glioma Growth is Controlled by MicroRNA-10b
G. Gabriely, M. Yi, Ravi S. Narayan, Johanna M. Niers +8 more
2011Cancer Research306 citations Open access
Semantic Scholar
Antisense Inhibition of microRNA-21 or -221 Arrests Cell Cycle, Induces Apoptosis, and Sensitizes the Effects of Gemcitabine in Pancreatic Adenocarcinoma
Jong-Kook Park, E. J. Lee, Christine Esau, Thomas D. Schmittgen
2009Pancreas295 citations
Semantic Scholar
Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase-1.
G. Jiang, Zhihua Li, Franklin Liu, K. Ellsworth +9 more
2005Journal of Clinical Investigation286 citations Open access
Semantic Scholar
De-repression of FOXO3a death axis by microRNA-132 and -212 causes neuronal apoptosis in Alzheimer's disease.
H. Wong, Tatiana Veremeyko, Nehal J. Patel, C. Lemere +4 more
2013Human Molecular Genetics282 citations Open access
Semantic Scholar
MyomiR-133 regulates brown fat differentiation through Prdm16
M. Trajkovski, Kashan Ahmed, Christine Esau, M. Stoffel
2012Nature Cell Biology264 citations Open access
Semantic Scholar
Inhibition of microRNA with antisense oligonucleotides.
Christine Esau
2008Methods260 citations
Semantic Scholar
Therapeutic potential for microRNAs.
Christine Esau, B. Monia
2007Advanced Drug Delivery Reviews230 citations
Semantic Scholar
Potent inhibition of microRNA in vivo without degradation
Scott Davis, Stephanie S. Propp, S. Freier, Laura E. Jones +6 more
2008Nucleic Acids Research194 citations Open access
Semantic Scholar
Therapeutic silencing of microRNA-33 inhibits the progression of atherosclerosis in Ldlr−/− mice
N. Rotllan, C. Ramírez, Binod Aryal, Christine Esau +1 more
2013Arteriosclerosis, Thrombosis and Vascular Biology183 citations Open access
Semantic Scholar
miR-132 and miR-212 are increased in pancreatic cancer and target the retinoblastoma tumor suppressor
Jong-Kook Park, Jon C. Henry, Jin-Mai Jiang, Christine Esau +5 more
2011Biochemical and Biophysical Research Communications - BBRC174 citations Open access
Semantic Scholar
Long-term therapeutic silencing of miR-33 increases circulating triglyceride levels and hepatic lipid accumulation in mice
L. Goedeke, A. Salerno, C. Ramírez, Liang Guo +10 more
2014EMBO Molecular Medicine149 citations Open access
Semantic Scholar
MicroRNA-144 Regulates Hepatic ABCA1 and Plasma HDL Following Activation of the Nuclear Receptor FXR
T. Q. de Aguiar Vallim, E. Tarling, Tammy Kim, M. Civelek +3 more
2013Circulation Research143 citations Open access
Semantic Scholar
microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain
Jaekwang Kim, Hyejin Yoon, Takahiro Horie, Jack M Burchett +12 more
2015Journal of Neuroscience120 citations Open access
Semantic Scholar
An SREBP Responsive micro-RNA Operon Contributes to a Regulatory Loop for Intracellular Lipid Homeostasis
Tae-Il Jeon, Ryan M. Esquejo, Manuel Roqueta‐Rivera, Peter E. Phelan +4 more
2013Cell Metabolism115 citations Open access
Semantic Scholar
MicroRNA-122 Modulates the Rhythmic Expression Profile of the Circadian Deadenylase Nocturnin in Mouse Liver
Shihoko Kojima, D. Gatfield, Christine Esau, C. B. Green
2010PLoS ONE95 citations Open access
Semantic Scholar
Let-7 coordinately suppresses components of the amino acid sensing pathway to repress mTORC1 and induce autophagy
Amy N. Dubinsky, S. Dastidar, C. Hsu, Rabaab Zahra +14 more
2014Cell Metabolism85 citations Open access
Semantic Scholar
A Screen in Mice Uncovers Repression of Lipoprotein Lipase by MicroRNA-29a as a Mechanism for Lipid Distribution Away From the Liver
Aras N. Mattis, Guisheng Song, Kelly Hitchner, Roy Y. Kim +11 more
2014Hepatology63 citations Open access
Semantic Scholar
Deletion of Calcineurin and Myocyte Enhancer Factor 2 (MEF2) Binding Domain of Cabin1 Results in Enhanced Cytokine Gene Expression in T Cells
Christine Esau, M. Boes, H. Youn, L. Tatterson +2 more
2001Journal of Experimental Medicine63 citations Open access
Semantic Scholar
Identification and functional validation of PNAs that inhibit murine CD40 expression by redirection of splicing.
A. Siwkowski, Leila Malik, Christine Esau, Martin A. Maier +5 more
2004Nucleic Acids Research53 citations Open access
Semantic Scholar
Metabolic and energetic benefits of microRNA-22 inhibition
M. Thibonnier, Christine Esau, Sujoy Ghosh, E. Wargent +1 more
2020BMJ Open Diabetes Research & Care34 citations Open access
Semantic Scholar
Abstract 76: MicroRNA-144 Regulates Hepatic ABCA1 and Plasma HDL Following Activation of the Nuclear Receptor FXR
T. Q. de Aguiar Vallim, E. Tarling, Tammy Kim, M. Civelek +3 more
201331 citations
Semantic Scholar
Evaluation of basic amphipathic peptides for cellular delivery of antisense peptide nucleic acids.
Martin A. Maier, Christine Esau, Andrew M. Siwkowski, E. Wancewicz +8 more
2006Journal of Medicinal Chemistry24 citations
Semantic Scholar
Metabolic Benefits of MicroRNA-22 Inhibition
M. Thibonnier, Christine Esau
2019Nucleic Acid Therapeutics22 citations
Semantic Scholar
MiR-21 Promotes Glioma Invasion by Targeting MMP Regulators.
G. Gabriely, T. Wurdinger, S. Kesari, Christine Esau +3 more
200818 citations
Semantic Scholar
MicroRNA-144 Regulates Hepatic ABCA1 and Plasma HDL Following Activation of the Nuclear Receptor FXR
T. Q. de Aguiar Vallim, E. Tarling, Tammy Kim, M. Civelek +3 more
20135 citations
Semantic Scholar
2′-O-Methoxyethyl/2′-Fluoro Modified Oligonucleotides Result in More Potent Inhibition of micro RNA-122 in Vivo: A Target implicatedin HCV Replication
B. Bhat, Christine Esau, Scott Davis, Stephanie S. Propp +5 more
20085 citations Open access
Semantic Scholar
P0907 : Pharmacokinetics, pharmacodynamics, and toxicity profile of RG-101, a novel GalNAc-conjugated hepatocyte-targetng inhibitor of microrna-122, in rodents and cynomolgus monkeys
S. Neben, Kai-zhen Liu, C. Berman, J. Tay +6 more
20153 citations
Semantic Scholar
Therapeutic modulation of microRNAs
B. Chau, Christine Esau, D. Mackenna, S. Neben +1 more
20132 citations
Semantic Scholar
Abstract 692: Therapeutic Inhibition of miR-33 Does Not Promote Obesity, Insulin Resistance or Hepatic Lipid Accumulation
D. Karunakaran, M. Geoffrion, Danyk Barrett, M. Harper +2 more
20151 citations
Semantic Scholar
Abstract 624: MiR-33 Antagonism Prevents the Progression of Atherosclerosis by Promoting an M2 Macrophage Phenotype
H. Ediriweera, M. Ouimet, Frederick J. Sheedy, Katey J. Rayner +6 more
2014Arteriosclerosis, Thrombosis and Vascular Biology1 citations
Semantic Scholar
Abstract 18944: The Mir-33 Locus Coordinately Regulates Macrophage Autophagy
M. Ouimet, H. Ediriweera, Bhama Ramkhelawon, R. Singaravelu +7 more
20160 citations
Semantic Scholar
Abstract 127: Effects of miR-33 Antagonism on Glucose and Triglyceride Metabolism in Nonhuman Primates.
Joseph D. Layne, Allison L. Mcdaniel, Stephanie M. Marshall, K. Kavanagh +3 more
20150 citations
Semantic Scholar
Abstract 422: Metabolic Regulation by miR-33 in Macrophages Controls Immune Effector Responses
M. Ouimet, H. Ediriweera, U. M. Gundra, Katey J. Rayner +10 more
2015Arteriosclerosis, Thrombosis and Vascular Biology0 citations
Semantic Scholar
Abstract 29: MiR-33 Coordinately Regulates Macrophage Autophagy
Mireille I. Ouimet, H. Ediriweera, Bhama Ramkhelawon, E. J. Hennessy +7 more
20140 citations
Semantic Scholar
Abstract 262: Anti-miR33 Therapy Promotes PGC1α Expression, Mitochondrial Function and Immunometabolic Pathways in Macrophages in Atherosclerosis
D. Karunakaran, A. B. Thrush, Eleni Ramphos, Zong Wu +5 more
20140 citations
Semantic Scholar
Abstract 446: Therapeutic Silencing of MicroRna-33 In Mice Inhibits the Progression of Atherosclerosis in Ldlr-/- Mice
N. Rotllan, C. Ramírez, Christine Esau, C. Fernández-Hernando
2013Arteriosclerosis, Thrombosis and Vascular Biology0 citations
Semantic Scholar
Abstract 22: OSBPL6 is a Novel miR-33 Target Gene Involved in Cellular Cholesterol Efflux
E. J. Hennessy, Katey J. Rayner, A. Sokolovska, M. Ouimet +2 more
20130 citations
Semantic Scholar
Abstract 45: Antiatherosclerotic Effects of miR-33 Inhibition: Increased Reverse Cholesterol Transport and Alternative-Activation (M2) of Macrophages
Katey J. Rayner, Frederick J. Sheedy, Christine Esau, F. Hussain +9 more
20120 citations
Semantic Scholar
Abstract 13280: Inhibition of miR-33a and b in Non-Human Primates Raises Plasma HDL Cholesterol and Reduces VLDL Triglycerides
Ryan E. Temel, Katey J. Rayner, Christine Esau, Allison L. Mcdaniel +6 more
20110 citations
Semantic Scholar

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