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Jonathan W. Lo · SciRah

Researcher profile · Semantic Scholar

Jonathan W. Lo

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Jonathan W. Lo — researcher profile on SciRah

h-index: 8
Works: 43
Citations: 390

Most-cited papers

Interleukin-22 regulates neutrophil recruitment in ulcerative colitis and is associated with resistance to ustekinumab therapy
P. Pavlidis, Anastasia Tsakmaki, Eirini Pantazi, Katherine Li +21 more
2022Nature Communications137 citations Open access
Semantic Scholar
Interleukin 6 Increases Production of Cytokines by Colonic Innate Lymphoid Cells in Mice and Patients With Chronic Intestinal Inflammation
N. Powell, Jonathan W. Lo, P. Biancheri, A. Vossenkämper +16 more
2015Gastroenterology89 citations Open access
Semantic Scholar
Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease
J. Canavan, C. Scottà, A. Vossenkämper, R. Goldberg +17 more
2015Gut44 citations Open access
Semantic Scholar
Immune checkpoint inhibitor-induced colitis is mediated by polyfunctional lymphocytes and is dependent on an IL23/IFNγ axis
Jonathan W. Lo, D. Cozzetto, James L Alexander, Nathan P. Danckert +15 more
2023Nature Communications33 citations Open access
Semantic Scholar
CTLA-4 expressing innate lymphoid cells modulate mucosal homeostasis in a microbiota dependent manner
Jonathan W. Lo, Jan-Hendrik Schroeder, L. Roberts, Rami Mohamed +14 more
2024Nature Communications21 citations Open access
Semantic Scholar
Sustained Post-Developmental T-Bet Expression Is Critical for the Maintenance of Type One Innate Lymphoid Cells In Vivo
Jan-Hendrik Schroeder, L. Roberts, Katrin Meissl, Jonathan W. Lo +11 more
2021bioRxiv19 citations Open access
Semantic Scholar
T-Bet Controls Cellularity of Intestinal Group 3 Innate Lymphoid Cells
Jan-Hendrik Schroeder, Katrin Meissl, Dominika Hromadová, Jonathan W. Lo +6 more
2021Frontiers in Immunology18 citations Open access
Semantic Scholar
A population of naive‐like CD4+ T cells stably polarized to the TH1 lineage
Jonathan W. Lo, Maria Vila de Mucha, S. Henderson, L. Roberts +12 more
2022European Journal of Immunology8 citations Open access
Semantic Scholar
Neutralising antibody responses against SARS-CoV-2 Omicron BA.4/5 and wild-type virus in patients with inflammatory bowel disease following three doses of COVID-19 vaccine (VIP): a prospective, multicentre, cohort study
Zhigang Liu, James L. Alexander, K. Le, Xin Zhou +68 more
2023EClinicalMedicine7 citations Open access
Semantic Scholar
Cyclin-dependent Kinase 9 as a Potential Target for Anti-TNF-resistant Inflammatory Bowel Disease
O. Omer, Arnulf Hertweck, L. Roberts, Jonathan W. Lo +8 more
2022Cellular and Molecular Gastroenterology and Hepatology6 citations Open access
Semantic Scholar
CD90 is not constitutively expressed in functional innate lymphoid cells
Jan-Hendrik Schroeder, Gordon Beattie, Jonathan W. Lo, T. Zabinski +4 more
2022bioRxiv5 citations Open access
Semantic Scholar
Immune checkpoint inhibitor-induced colitis is mediated by CXCR6+ polyfunctional lymphocytes and is dependent on the IL23/IFNγ axis
Jonathan W. Lo, D. Cozzetto, Zhigang Liu, H. Ibraheim +12 more
20222 citations Open access
Semantic Scholar
HoTResDB: host transcriptional response database for viral hemorrhagic fevers
Jonathan W. Lo, Deric Zhang, Emily Speranza, J. A. Negron +1 more
2017Bioinform.1 citations Open access
Semantic Scholar
Tu1677 Down-Modulation of Intestinal Production of Pro-Inflammatory Cytokines in Experimental Colitis and in Inflammatory Bowel Disease by a Narrow Spectrum Kinase Inhibitor
P. Biancheri, R. Curciarello, N. Powell, Jonathan W. Lo +8 more
20131 citations
Semantic Scholar
A microbiota-responsive polyfunctional cytotoxic CD4⁺ T-cell state promotes mucosal inflammation in ulcerative colitis
John P. Thomas, S. H. Kottoor, Jonathan W. Lo, Tyler Wooldridge +16 more
2026bioRxiv0 citations Open access
Semantic Scholar
P82 Depicting metabolite-microbiota interactions in a mouse model of immune checkpoint inhibitor-induced colitis
Zhigang Liu, James L. Alexander, Rui Zhang, Jonathan W. Lo +1 more
2024Poster Presentations0 citations
Semantic Scholar
Tu1734 BLOCKADE OF IL-27, BUT NOT IL-1B, ATTENUATES IMMUNE CHECKPOINT INHIBITOR COLITIS
H. Ibraheim, D. Cozzetto, Hiromi Kudo, R. Goldin +2 more
2024Gastroenterology0 citations
Semantic Scholar
Tu1775 UNVEILING METABOLITE-MICROBIOTA CROSSTALK IN A MURINE MODEL OF CHECKPOINT INHIBITOR-INDUCED COLITIS
Zhigang Liu, James L. Alexander, Rui Zhang, Jonathan W. Lo +1 more
2024Gastroenterology0 citations
Semantic Scholar
Sa1931 MOLECULAR PROFILING OF FFPE TISSUE IN PATIENTS WITH IMMUNE CHECKPOINT INHIBITOR INDUCED COLITIS HIGHLIGHTS NEW THERAPEUTIC TARGETS
H. Ibraheim, D. Cozzetto, Jonathan W. Lo, A. Cortellini +3 more
2023Gastroenterology0 citations
Semantic Scholar
DOP67 A transcriptional module associated with neutrophil degranulation is highly conserved across species and is a core molecular pathway of treatment resistance in ulcerative colitis
Domenico Cozzetto, Jonathan W. Lo, Nick Powell
2023Journal of Crohn's & Colitis0 citations Open access
Semantic Scholar
795: AN INTERLEUKIN 22/CHEMOKINE AXIS DRIVES COLONIC NEUTROPHIL RECRUITMENT AND TREATMENT RESISTANCE IN ULCERATIVE COLITIS
P. Pavlidis, Anastasia Tsakmaki, Eirini Pantazi, Katherine Li +20 more
2022Gastroenterology0 citations
Semantic Scholar
374: IMMUNE CHECKPOINT INHIBITOR-INDUCED COLITIS IS MEDIATED BY CYTOTOXIC LYMPHOCYTES AND IS RELIANT ON THE IL23/IFNγ AXIS
Jonathan W. Lo, D. Cozzetto, M. Madgwick, J. Sieh +12 more
2022Gastroenterology0 citations
Semantic Scholar
O32 The interleukin 22//neutrophil axis is associated with treatment resistance in ulcerative colitis
P. Pavlidis, Anastasia Tsakmaki, Eirini Pantazi, Katherine Li +20 more
2022Oral presentations0 citations
Semantic Scholar
P84 NKp46+ TRAIL- CD49b+ group 1 innate lymphoid cells mediate hepatitis in an interferon-γ dependent manner
Jonathan W. Lo, D. Cozzetto, É. Stolarczyk, P. Lavender +4 more
2022Poster presentations0 citations
Semantic Scholar
Mo1503: DYSREGULATED MICROBE-HOST METABOLISM UNDERPINS IMMUNE ACTIVATION IN A MICROBIOTA-DEPENDENT MODEL OF ULCERATIVE COLITIS
Zhigang Liu, Jonathan W. Lo, J. Alexander, D. Cozzetto +1 more
2022Gastroenterology0 citations
Semantic Scholar
O31 Dysregulated gut microbiota-host metabolism underpins immune activation in a microbiota-dependent model of ulcerative colitis
Zhigang Liu, Jonathan W. Lo, J. Alexander, D. Cozzetto +1 more
2022Oral presentations0 citations
Semantic Scholar
792: MICROBIOTA-RESPONSIVE CYTOTOXIC, POLYFUNCTIONAL CD4+ T CELLS ARE ENRICHED IN ULCERATIVE COLITIS AND ARE ASSOCIATED WITH RESISTANCE TO ANTI-CYTOKINE THERAPIES
S. Kottoor, D. Cozzetto, M. Madgwick, M. Olbei +7 more
2022Gastroenterology0 citations
Semantic Scholar
P38 Immune checkpoint inhibitor-induced colitis is mediated by CXCR6+ polyfunctional lymphocytes and dependent on IL23/IFNg axis
Jonathan W. Lo, D. Cozzetto, Zhigang Liu, H. Ibraheim +12 more
2022Poster presentations0 citations
Semantic Scholar
PMO-4 Immune checkpoint inhibitor-induced colitis is mediated by IL23 responsive CD90+ cytotoxic lymphocytes
Jonathan W. Lo, D. Cozzetto, Jillian Yong Xin Sieh, M. Madgwick +8 more
2021Posters0 citations
Semantic Scholar
A population of CD4+ T cells with a naïve phenotype stably polarized to the TH1 lineage
Jonathan W. Lo, Maria Vila de Mucha, L. Roberts, N. Garrido-Mesa +8 more
2020bioRxiv0 citations Open access
Semantic Scholar
Checkpoint Inhibitor Induced Colitis is Dependent on the Microbiota and Activation of Cytotoxic Innate and Adaptive Lymphocytes
Jonathan W. Lo, D. Cozzetto, Jan-Hendrik Schroeder, J. Sieh +17 more
20200 citations Open access
Semantic Scholar
Defining the role of the transcription factor T-bet in the immune system
Jonathan W. Lo
20190 citations
Semantic Scholar
Sa1751 Interleukin-6 Drives Production of Pathogenic Cytokines by Innate Lymphoid Cells in Patients and Mice With Chronic Intestinal Inflammation
N. Powell, Jonathan W. Lo, P. Biancheri, A. Vossenkämper +15 more
20150 citations
Semantic Scholar
Sa1675 Nkp46+ Innate Lymphocytes Mediate Acute Hepatitis Following Activation of Innate Immunity
N. Powell, Jonathan W. Lo, H. Kudo, É. Stolarczyk +6 more
20150 citations
Semantic Scholar
2014 British Transplant Society Conference
Manohursingh Runglall, I. Rebollo-Mesa, Y. Kamra, P. Mobillo +13 more
20140 citations
Semantic Scholar
2014 British Transplant Society Conference (Oral)
Manohursingh Runglall, I. Rebollo-Mesa, Y. Kamra, P. Mobillo +13 more
20140 citations
Semantic Scholar
2013 Digestive Disease Week.
J. Canavan, I. Shoval, Matthew J. Elder, H. Fazekasova +14 more
20130 citations
Semantic Scholar
272 In Vitro Generated Regulatory T Cells From Crohn's Disease Patients’ Blood Home to Inflamed Human Small Bowel In Vivo
J. Canavan, I. Shoval, Matthew J. Elder, H. Fazekasova +14 more
20130 citations Open access
Semantic Scholar
Su1266 In Vitro Generated Regulatory T Cells From Blood Suppress Mucosal Effector T Cells in Crohn's Disease Patients
J. Canavan, Matthew J. Elder, H. Fazekasova, N. Powell +11 more
20130 citations
Semantic Scholar
P002 Intestinal homeostasis is critically regulated by the transcription factor T-bet
N. Powell, É. Stolarczyk, Jonathan W. Lo, J. Canavan +3 more
20130 citations Open access
Semantic Scholar
2013 British Transplant Society Annual Congress
Manohursingh Runglall, I. Rebollo-Mesa, Y. Kamra, Jonathan W. Lo +10 more
20130 citations
Semantic Scholar
2013 Digestive Disease Week. AGA-Horizon Pharma Fellow Abstract Prize
J. Canavan, I. Shoval, Matthew J. Elder, H. Fazekasova +14 more
20130 citations
Semantic Scholar
2012 The 3rd International Conference on Transplantomics and Biomarkers in Organ Transplantation
Manohursingh Runglall, I. Rebollo-Mesa, Y. Kamra, Jonathan W. Lo +11 more
20120 citations
Semantic Scholar

Frequent co-authors

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Graham M Lord×27
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Graham M Lord — researcher profile on SciRah
D. Cozzetto×16
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D. Cozzetto — researcher profile on SciRah
N. Powell×15
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N. Powell — researcher profile on SciRah
M. Madgwick×12
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M. Madgwick — researcher profile on SciRah

×12

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É. Stolarczyk — researcher profile on SciRah

T. Korcsmáros×11

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T. Korcsmáros — researcher profile on SciRah

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N. Powell — researcher profile on SciRah

H. Ibraheim×10

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H. Ibraheim — researcher profile on SciRah

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R. Goldin — researcher profile on SciRah

T. Macdonald×9

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T. Macdonald — researcher profile on SciRah

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J. Canavan — researcher profile on SciRah

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P. Irving — researcher profile on SciRah