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J. Canavan · SciRah

Researcher profile · Semantic Scholar

J. Canavan

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J. Canavan — researcher profile on SciRah

h-index: 18
Works: 88
Citations: 1,553

Most-cited papers

The Transcription Factor T-bet Regulates Intestinal Inflammation Mediated by Interleukin-7 Receptor+ Innate Lymphoid Cells
N. Powell, A. Walker, É. Stolarczyk, J. Canavan +10 more
2012Immunity331 citations Open access
Semantic Scholar
Infection and systemic inflammation, not ammonia, are associated with Grade 3/4 hepatic encephalopathy, but not mortality in cirrhosis.
D. Shawcross, Y. Sharifi, J. Canavan, A. Yeoman +5 more
2011Journal of Hepatology269 citations
Semantic Scholar
Improved Insulin Sensitivity despite Increased Visceral Adiposity in Mice Deficient for the Immune Cell Transcription Factor T-bet
É. Stolarczyk, C. Vong, E. Perucha, I. Jackson +6 more
2013Cell Metabolism100 citations Open access
Semantic Scholar
A rapid diagnostic test for human regulatory T-cell function to enable regulatory T-cell therapy
J. Canavan, B. Afzali, C. Scottà, H. Fazekasova +5 more
2012Blood91 citations Open access
Semantic Scholar
Interleukin 6 Increases Production of Cytokines by Colonic Innate Lymphoid Cells in Mice and Patients With Chronic Intestinal Inflammation
N. Powell, Jonathan W. Lo, P. Biancheri, A. Vossenkämper +16 more
2015Gastroenterology89 citations Open access
Semantic Scholar
Molecular Comparison of Adult and Pediatric Ulcerative Colitis Indicates Broad Similarity of Molecular Pathways in Disease Tissue
Katherine Li, R. Strauss, J. Ouahed, D. Chan +6 more
2018Journal of Pediatric Gastroenterology and Nutrition - JPGN88 citations
Semantic Scholar
Comparison of regulatory T cells in hemodialysis patients and healthy controls: implications for cell therapy in transplantation.
B. Afzali, F. Edozie, H. Fazekasova, C. Scottà +10 more
2013American Society of Nephrology. Clinical Journal81 citations Open access
Semantic Scholar
Determining the economic cost of ICU treatment: a prospective “micro-costing” study
A. McLaughlin, J. Hardt, J. Canavan, M. Donnelly
2009Intensive Care Medicine59 citations
Semantic Scholar
Full, Partial, and Modified Permutations of the Mayo Score: Characterizing Clinical and Patient-Reported Outcomes in Ulcerative Colitis Patients
A. Naegeli, T. Hunter, Yan Dong, B. Hoskin +4 more
2021Crohn's & Colitis 36054 citations Open access
Semantic Scholar
High-dimensional immune phenotyping and transcriptional analyses reveal robust recovery of viable human immune and epithelial cells from frozen gastrointestinal tissue
L. Konnikova, G. Boschetti, A. Rahman, V. Mitsialis +15 more
2018Mucosal Immunology46 citations Open access
Semantic Scholar
Efficacy and Safety of Approximately 3 Years of Continuous Ozanimod in Moderately to Severely Active Ulcerative Colitis: Interim Analysis of the True North Open-label Extension
S. Danese, R. Panaccione, M. Abreu, David T. Rubin +15 more
2023Journal of Crohn's & Colitis42 citations Open access
Semantic Scholar
Relative Resistance of Human CD4+ Memory T Cells to Suppression by CD4+CD25+ Regulatory T Cells
B. Afzali, P. Mitchell, C. Scottà, J. Canavan +8 more
2011American Journal of Transplantation39 citations Open access
Semantic Scholar
Artificial Intelligence in Inflammatory Bowel Disease Endoscopy: Implications for Clinical Trials
H. Ahmad, J. East, R. Panaccione, S. Travis +3 more
2023Journal of Crohn's & Colitis37 citations Open access
Semantic Scholar
Low-Dose Interleukin-2 Ameliorates Colitis in a Preclinical Humanized Mouse Model
J. Goettel, D. Kotlarz, Rohini Emani, J. Canavan +17 more
2019Cellular and Molecular Gastroenterology and Hepatology33 citations Open access
Semantic Scholar
Artificial intelligence in inflammatory bowel disease: implications for clinical practice and future directions
H. Ahmad, J. East, R. Panaccione, S. Travis +3 more
2023Intestinal Research28 citations Open access
Semantic Scholar
Transcriptional regulation of the mucosal immune system mediated by T-bet
N. Powell, J. Canavan, T. Macdonald, Graham M Lord
2010Mucosal Immunology22 citations Open access
Semantic Scholar
Significant psychological morbidity occurs in irritable bowel syndrome: a case‐control study using a pharmacy reimbursement database
J. Canavan, K. Bennett, J. Feely, C. O'Moráin +1 more
2009Alimentary Pharmacology and Therapeutics19 citations
Semantic Scholar
Immunologic Alterations Associated With Oral Delivery of Anti-CD3 (OKT3) Monoclonal Antibodies in Patients With Moderate-to-Severe Ulcerative Colitis
Elisa K Boden, J. Canavan, C. Moran, Katelyn J. McCann +10 more
2019Crohn's & Colitis 36018 citations Open access
Semantic Scholar
A survey of MRSA awareness and knowledge among the general public and patients' visitors
A. McLaughlin, J. Canavan, E. Adams, R. Mcdonagh +3 more
200814 citations
Semantic Scholar
LOW DOSE IL-2 FOR THE TREATMENT OF MODERATE TO SEVERE ULCERATIVE COLITIS
J. Allegretti, J. Canavan, V. Mitsialis, Matthew J. Hamilton +12 more
2021Gastroenterology13 citations
Semantic Scholar
Mucosal Gene Expression in Pediatric and Adult Patients With Ulcerative Colitis Permits Modeling of Ideal Biopsy Collection Strategy for Transcriptomic Analysis
J. Ouahed, William Gordon, J. Canavan, Huan-Yu Zhou +20 more
2018Inflammatory Bowel Diseases11 citations Open access
Semantic Scholar
An unusual case of dyspnoea in an elderly man
P. Trivedi, J. Canavan, C. Holloway, A. Slater +1 more
2010BMJ Case Reports7 citations Open access
Semantic Scholar
Acute Fulminant Colitis Caused by Idiopathic Mesenteric Inflammatory Veno-Occlusive Disease
J. Canavan, A. Coss, M. Leader, S. Patchett
2007Case Reports in Gastroenterology7 citations Open access
Semantic Scholar
OP38 Maintenance treatment with mirikizumab, a p19-directed IL-23 antibody: 52-week results in patients with moderately-to-severely active ulcerative colitis
G. D'Haens, W. Sandborn, M. Ferrante, B. Bhandari +8 more
2019Journal of Crohn's & Colitis6 citations
Semantic Scholar
P243 Faecal incontinence in inflammatory bowel disease: we don't ask and they don't tell
J. Duncan, G. Sebepos-Rogers, O. Poole-Wilson, J. Canavan +11 more
20136 citations Open access
Semantic Scholar
Tu1849 HISTOLOGIC REMISSION AND MUCOSAL HEALING IN A PHASE 2 STUDY OF MIRIKIZUMAB IN PATIENTS WITH MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS
R. Pai, J. Canavan, J. Tuttle, M. Durante +6 more
20205 citations
Semantic Scholar
O-011 Low-dose IL-2 Administration Expands Human Regulatory T Cells in Patients with UC and Humanized Mice and Protects Against Experimental Colitis
J. Goettel, D. Kotlarz, D. Illig, J. Canavan +9 more
2017Inflammatory Bowel Diseases5 citations
Semantic Scholar
Assessment of regulatory T-cell function in forthcoming clinical trials of cell therapy
J. Canavan, B. Afzali, Graham M Lord, G. Lombardi
2013Expert Review of Molecular Diagnostics5 citations Open access
Semantic Scholar
DOP43 Extended induction in the True North OLE study: ozanimod efficacy in biologic-naive and biologic-experienced patients
A. Dignass, M. Regueiro, J. Colombel, A. Jain +6 more
2023Journal of Crohn's & Colitis3 citations
Semantic Scholar
DOP37 Efficacy and safety of 3 years of continuous ozanimod treatment: an interim analysis of the True North open-label extension study
S. Danese, M. Abreu, D. Wolf, J. Canavan +6 more
2023Journal of Crohn's & Colitis3 citations Open access
Semantic Scholar
P609 Impact of prior biologic exposure on durability of recaptured response to ozanimod during the True North open-label extension study
J. Colombel, D. Rubin, S. Vermeire, A. Jain +6 more
2023Journal of Crohn's & Colitis2 citations Open access
Semantic Scholar
P405 Long-term safety of 3 years of ozanimod in moderately to severely active ulcerative colitis: an interim analysis of the True North open-label extension
R. Panaccione, S. Danese, D. Wolf, J. Canavan +6 more
2023Journal of Crohn's & Colitis2 citations
Semantic Scholar
P376 Efficacy of ozanimod in vedolizumab-exposed patients with ulcerative colitis: a phase 3 True North post hoc analysis
B. Sands, A. Jain, H. Ahmad, M. Osterman +3 more
2023Journal of Crohn's & Colitis2 citations Open access
Semantic Scholar
Full, Partial, or Modified: Understanding Relationships Between Permutations of the Mayo Score in Real-World Ulcerative Colitis Patients
A. Naegeli, Xiang Zhang, T. Hunter, B. Hoskin +4 more
2018American Journal of Gastroenterology2 citations
Semantic Scholar
O-003 The Brain as Extraintestinal IBD Manifestation: Are Brain and Cognitive Differences in Pediatric Crohn's Disease Associated with Immune Gene Expression?
C. Mrakotsky, Dunn W. Augustine, Christopher G. Watson, J. Canavan +2 more
2017Inflammatory Bowel Diseases2 citations
Semantic Scholar
The Diagnostic Value of Endoscopy in Evaluating Non-Cardiac Chest Pain
J. Canavan, R. J. Grainger, F. Murray, S. Patchett
20052 citations Open access
Semantic Scholar
Going the Extra Inch: Quantifying the Benefits of Terminal Ileal Intubation
J. Canavan, E. Kay, S. Patchett, F. Murray
20042 citations
Semantic Scholar
P773 Extended induction in the True North open-label extension study: clinical outcomes of ~2 years of ozanimod treatment
David T. Rubin, J. Colombel, M. Chiorean, Subrata Ghosh +6 more
2023Journal of Crohn's & Colitis1 citations
Semantic Scholar
Tu1725 EFFECTS OF OZANIMOD ON HISTOLOGIC REMISSION AND MUCOSAL HEALING OVER 3 YEARS OF CONTINUOUS TREATMENT IN PATIENTS WITH ULCERATIVE COLITIS
M. Abreu, S. Danese, D. Wolf, J. Canavan +5 more
2023Gastroenterology1 citations
Semantic Scholar
P715 Achievement and maintenance of endoscopic, histologic, and combined outcomes after extended induction in Week 10 nonresponders of ozanimod: 2-year interim analysis of the True North open-label extension study
S. Vermeire, J. Colombel, D. Rubin, S. Ghosh +6 more
2023Journal of Crohn's & Colitis1 citations Open access
Semantic Scholar
P464 Effects of ozanimod on histologic remission and mucosal healing over 3 years of continuous treatment in patients with ulcerative colitis
R. Panaccione, S. Danese, D. Wolf, J. Canavan +5 more
2023Journal of Crohn's & Colitis1 citations Open access
Semantic Scholar
P687 Durability of recaptured response to ozanimod during the True North open-label extension
A. Dignass, M. Regueiro, J. Colombel, A. Jain +6 more
2023Journal of Crohn's & Colitis1 citations Open access
Semantic Scholar
S723 Duration of Response to Ozanimod After Treatment Withdrawal: Results From the Phase 3 True North Study
B. Sands, B. Abraham, B. Bressler, W. Reinisch +7 more
2022Gastroenterology & hepatology1 citations
Semantic Scholar
1004 – Maintenence Treatment with Mirikizumab, a P19-Directed Il-23 Antibody: 52-Week Results in Patients with Moderately-Toseverely Active Ulcerative Colitis
G. D'Haens, W. Sandborn, M. Ferrante, B. Bhandari +8 more
2019Gastroenterology1 citations Open access
Semantic Scholar
Fracture Risk Assessment Using DXA and FRAX in Patients with Celiac Disease
J. Canavan, P. Trivedi, A. Bailey, Sandra Nichols +3 more
20091 citations
Semantic Scholar
DEFINING THE OUTCOME, PRECIPITANTS AND COST OF SEVERE HEPATIC ENCEPHALOPATHY (HE) IN CIRRHOSIS
Y. Sharifi, J. Canavan, A. Yeoman, R. Abeles +8 more
20081 citations
Semantic Scholar
P752 Predictors of time to relapse upon ozanimod withdrawal in patients with moderately to severely active ulcerative colitis
S. Vermeire, B. Abraham, B. Bressler, W. Reinisch +8 more
2023Journal of Crohn's & Colitis0 citations
Semantic Scholar
Tu1745 ACHIEVEMENT AND MAINTENANCE OF ENDOSCOPIC, HISTOLOGIC, AND COMBINED OUTCOMES AFTER EXTENDED INDUCTION IN WEEK 10 NONRESPONDERS OF OZANIMOD: 2-YEAR INTERIM ANALYSIS OF THE TRUE NORTH OPEN-LABEL EXTENSION STUDY
M. Chiorean, J. Colombel, David T. Rubin, Subrata Ghosh +6 more
2023Gastroenterology0 citations
Semantic Scholar
950 LONG-TERM SAFETY OF 3 YEARS OF OZANIMOD IN MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS: AN INTERIM ANALYSIS OF THE TRUE NORTH OPEN-LABEL EXTENSION
M. Abreu, S. Danese, D. Wolf, J. Canavan +6 more
2023Gastroenterology0 citations
Semantic Scholar
P719 Symptomatic improvement and long-term stability of ulcerative colitis symptoms over 3 years of ozanimod treatment
S. Danese, M. Abreu, A. Afzali, J. Canavan +5 more
2023Journal of Crohn's & Colitis0 citations Open access
Semantic Scholar

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