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C. Scottà · SciRah

Researcher profile · Semantic Scholar

C. Scottà

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C. Scottà — researcher profile on SciRah

h-index: 29
Works: 73
Citations: 4,141

Most-cited papers

Guidelines for the use of flow cytometry and cell sorting in immunological studies
A. Cossarizza, Hyun-Dong Chang, Andreas Radbruch, M. Akdiş +232 more
2017European Journal of Immunology1,153 citations Open access
Semantic Scholar
Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials
B. Sawitzki, P. Harden, P. Reinke, A. Moreau +57 more
2020The Lancet394 citations Open access
Semantic Scholar
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)
A. Cossarizza, Hyun-Dong Chang, A. Radbruch, A. Acs +432 more
2019European Journal of Immunology306 citations Open access
Semantic Scholar
Differential effects of rapamycin and retinoic acid on expansion, stability and suppressive qualities of human CD4+CD25+FOXP3+ T regulatory cell subpopulations
C. Scottà, M. Esposito, H. Fazekasova, G. Fanelli +8 more
2013Haematologica146 citations Open access
Semantic Scholar
A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials
H. Fraser, N. Safinia, Nathali Grageda, Sarah Thirkell +12 more
2018Molecular Therapy: Methods & Clinical Development131 citations Open access
Semantic Scholar
CD161 expression characterizes a sub-population of human regulatory T cells that produces IL-17 in a STAT3 dependent manner
B. Afzali, P. Mitchell, F. Edozie, G. A. Povoleri +17 more
2013European Journal of Immunology119 citations Open access
Semantic Scholar
Regulatory T Cells: Serious Contenders in the Promise for Immunological Tolerance in Transplantation
N. Safinia, C. Scottà, T. Vaikunthanathan, R. Lechler +1 more
2015Frontiers in Immunology114 citations Open access
Semantic Scholar
Feasibility, long-term safety, and immune monitoring of regulatory T cell therapy in living donor kidney transplant recipients
Paul N. Harden, D. Game, B. Sawitzki, J. B. van der Net +19 more
2020American Journal of Transplantation105 citations Open access
Semantic Scholar
Thymic Versus Induced Regulatory T Cells – Who Regulates the Regulators?
Giovanni A. M. Povoleri, C. Scottà, E. Nova-Lamperti, S. John +2 more
2013Frontiers in Immunology100 citations Open access
Semantic Scholar
Human retinoic acid-regulated CD161+ regulatory T cells support wound repair in intestinal mucosa
Giovanni A. M. Povoleri, E. Nova-Lamperti, C. Scottà, G. Fanelli +21 more
2018Nature Immunology97 citations Open access
Semantic Scholar
Echinococcus granulosus‐specific T‐cell lines derived from patients at various clinical stages of cystic echinococcosis
R. Riganò, B. Buttari, E. de Falco, E. Profumo +5 more
2004Parasite immunology (Print)97 citations
Semantic Scholar
A rapid diagnostic test for human regulatory T-cell function to enable regulatory T-cell therapy
J. Canavan, B. Afzali, C. Scottà, H. Fazekasova +5 more
2012Blood91 citations Open access
Semantic Scholar
Hypervariable region 1 variants act as TCR antagonists for hepatitis C virus-specific CD4+ T cells.
L. Frasca, P. Del Porto, L. Tuosto, B. Marinari +4 more
1999Journal of Immunology90 citations
Semantic Scholar
Comparison of regulatory T cells in hemodialysis patients and healthy controls: implications for cell therapy in transplantation.
B. Afzali, F. Edozie, H. Fazekasova, C. Scottà +10 more
2013American Society of Nephrology. Clinical Journal81 citations Open access
Semantic Scholar
Getting to the Heart of the Matter: The Role of Regulatory T-Cells (Tregs) in Cardiovascular Disease (CVD) and Atherosclerosis
C. J. Albany, S. Trevelin, G. Giganti, G. Lombardi +1 more
2019Frontiers in Immunology77 citations Open access
Semantic Scholar
Expanded Regulatory T Cells Induce Alternatively Activated Monocytes With a Reduced Capacity to Expand T Helper-17 Cells
M. Romano, G. Fanelli, Nicole Y. Tan, E. Nova-Lamperti +4 more
2018Frontiers in Immunology76 citations Open access
Semantic Scholar
Impact of immunosuppressive drugs on the therapeutic efficacy of ex vivo expanded human regulatory T cells
C. Scottà, G. Fanelli, S. Hoong, M. Romano +9 more
2016Haematologica76 citations Open access
Semantic Scholar
Treg cell therapy: How cell heterogeneity can make the difference
G. Giganti, M. Atif, Y. Mohseni, D. Mastronicola +4 more
2020European Journal of Immunology73 citations Open access
Semantic Scholar
Regulatory T-cell therapy in the induction of transplant tolerance: the issue of subpopulations.
F. Edozie, E. Nova-Lamperti, G. A. Povoleri, C. Scottà +3 more
2014Transplantation73 citations Open access
Semantic Scholar
Cell Therapy in Organ Transplantation: Our Experience on the Clinical Translation of Regulatory T Cells
N. Safinia, Nathali Grageda, C. Scottà, Sarah Thirkell +4 more
2018Frontiers in Immunology67 citations Open access
Semantic Scholar
PD-L1 signaling on human memory CD4+ T cells induces a regulatory phenotype
G. Fanelli, M. Romano, Estefanía Nova-Lamperti, Mariana Werner Sunderland +10 more
2021PLoS Biology65 citations Open access
Semantic Scholar
Correction of Defective T-Regulatory Cells From Patients With Crohn's Disease by Ex Vivo Ligation of Retinoic Acid Receptor-α.
Rimma Goldberg, C. Scottà, D. Cooper, E. Nissim-Eliraz +12 more
2019Gastroenterology54 citations Open access
Semantic Scholar
Human Anergic CD4+ T Cells Can Act as Suppressor Cells by Affecting Autologous Dendritic Cell Conditioning and Survival1
L. Frasca, C. Scottà, G. Lombardi, E. Piccolella
2002Journal of Immunology50 citations Open access
Semantic Scholar
Positive selection of cytotoxic T lymphocyte escape variants during acute hepatitis C virus infection
S. Guglietta, A. Garbuglia, V. Pacciani, C. Scottà +12 more
2005European Journal of Immunology47 citations Open access
Semantic Scholar
Regulatory T Cells in Pregnancy Adverse Outcomes: A Systematic Review and Meta-Analysis
Samantha A. Green, M. Politis, Kathrine S. Rallis, A. Sáenz de Villaverde Cortabarría +8 more
2021Frontiers in Immunology45 citations Open access
Semantic Scholar
Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease
J. Canavan, C. Scottà, A. Vossenkämper, R. Goldberg +17 more
2015Gut44 citations Open access
Semantic Scholar
CD28 costimulation regulates FOXP3 in a RelA/NF‐κB‐dependent mechanism
M. Soligo, Cristina Camperio, S. Caristi, C. Scottà +5 more
2011European Journal of Immunology42 citations Open access
Semantic Scholar
Relative Resistance of Human CD4+ Memory T Cells to Suppression by CD4+CD25+ Regulatory T Cells
B. Afzali, P. Mitchell, C. Scottà, J. Canavan +8 more
2011American Journal of Transplantation39 citations Open access
Semantic Scholar
Chimeric antigen receptor‐modified human regulatory T cells that constitutively express IL‐10 maintain their phenotype and are potently suppressive
Y. Mohseni, Adeel Saleem, S. Tung, Caroline Dudreuilh +12 more
2021European Journal of Immunology35 citations Open access
Semantic Scholar
Spatiotemporal in vivo tracking of polyclonal human regulatory T cells (Tregs) reveals a role for innate immune cells in Treg transplant recruitment
Jacinta Jacob, S. Nadkarni, Alessia Volpe, Q. Peng +9 more
2020Molecular Therapy: Methods & Clinical Development26 citations Open access
Semantic Scholar
FOXP3 Induced by CD28/B7 Interaction Regulates CD25 and Anergic Phenotype in Human CD4+CD25− T Lymphocytes1
C. Scottà, M. Soligo, Cristina Camperio, E. Piccolella
2008Journal of Immunology25 citations Open access
Semantic Scholar
Cell therapy to promote transplantation tolerance: a winning strategy?
G. Lombardi, P. Sagoo, C. Scottà, H. Fazekasova +4 more
2011Immunotherapy23 citations
Semantic Scholar
Nanoneedle‐Based Electroporation for Efficient Manufacturing of Human Primary Chimeric Antigen Receptor Regulatory T‐Cells
Ningjia Sun, Cong Wang, William Edwards, Yi-Kai Wang +9 more
2025Advancement of science18 citations Open access
Semantic Scholar
Isolation and freezing of human peripheral blood mononuclear cells from pregnant patients
Athina Efthymiou, Nicoleta Mureanu, Rebecca Pemberton, Sarah Tai-Macarthur +5 more
2022STAR Protocols18 citations Open access
Semantic Scholar
Isolation and expansion of thymus‐derived regulatory T cells for use in pediatric heart transplant patients
Marco Romano, M. Sen, C. Scottà, R. Alhabbab +4 more
2021European Journal of Immunology18 citations Open access
Semantic Scholar
The Role of Regulatory T Cells and Their Therapeutic Potential in Hypertensive Disease of Pregnancy: A Literature Review
Kyle Headen, Vaidilė Jakaitė, Vita Andreja Mesarič, C. Scottà +3 more
2024International Journal of Molecular Sciences16 citations Open access
Semantic Scholar
Potential Application of T-Follicular Regulatory Cell Therapy in Transplantation
C. Dudreuilh, S. Basu, C. Scottà, A. Dorling +1 more
2021Frontiers in Immunology16 citations Open access
Semantic Scholar
Impact of viral selected mutations on T cell mediated immunity in chronically evolving and self limiting acute HCV infection.
S. Guglietta, A. Garbuglia, L. Salichos, L. Ruggeri +12 more
2009Virology15 citations Open access
Semantic Scholar
The Immunomodulatory Role of Regulatory T Cells in Preterm Birth and Associated Pregnancy Outcomes
Nicoleta Mureanu, A. Bowman, I. A. Porter-Wright, P. Verma +6 more
2024International Journal of Molecular Sciences12 citations Open access
Semantic Scholar
OMIP‐090: A 20‐parameter flow cytometry panel for rapid analysis of cell diversity and homing capacity in human conventional and regulatory T cells
Wladislaw Stroukov, D. Mastronicola, C. J. Albany, Zeynep Catak +2 more
2023Cytometry Part A12 citations Open access
Semantic Scholar
Antibody‐selected mimics of hepatitis C virus hypervariable region 1 activate both primary and memory Th lymphocytes
L. Frasca, C. Scottà, P. Del Porto, A. Nicosia +5 more
2003Hepatology12 citations Open access
Semantic Scholar
Differential effects of rapamycin and retinoic acid on expansion , stability and suppressive qualities of human CD 4 + CD 25 + FOXP 3 + Treg subpopulations
C. Scottà, M. Esposito, H. Fazekasova, G. Fanelli +9 more
20129 citations
Semantic Scholar
Can regulatory T cells improve outcomes of sensitised patients after HLA-Ab incompatible renal transplantation: study protocol for the Phase IIa GAMECHANgER-1 trial
C. Dudreuilh, P. Jarvis, N. Beadle, I. Pilecka +10 more
2023BMC Nephrology8 citations Open access
Semantic Scholar
Influence of specific CD4+ T cells and antibodies on evolution of hypervariable region 1 during acute HCV infection.
C. Scottà, A. Garbuglia, L. Ruggeri, E. Spada +9 more
2008Journal of Hepatology8 citations
Semantic Scholar
Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials (vol 395, pg 1627, 2020)
B. Sawitzki, Paul N. Harden, Petra Reinke, A. Moreau +57 more
20206 citations
Semantic Scholar
Hypervariable region 1 variant acting as TCR antagonist affects hepatitis C virus‐specific CD4+ T cell repertoire by favoring CD95‐mediated apoptosis
C. Scottà, L. Tuosto, A. Masci, L. Racioppi +2 more
2005Journal of Leukocyte Biology5 citations Open access
Semantic Scholar
Caveolar Endocytosis Governs Nanoneedle Transfection
Ningjia Sun, Cong Wang, Yi-Kai Wang, William Edwards +12 more
2026ACS Nano4 citations Open access
Semantic Scholar
The ONE Study: Evaluation of Regulatory Cell Therapy in Kidney Transplantation Using a Harmonized Trial Design
B. Sawitzki, P. Harden, P. Reinke, A. Moreau +57 more
20204 citations
Semantic Scholar
CAR-mediated release of IL-10 increases the function of regulatory T cells: Relevance for future clinical application
Adeel Saleem, Qi Peng, Zi-Qin Tang, Y. Mohseni +7 more
2026Molecular Therapy3 citations Open access
Semantic Scholar
Invariant natural killer T cells treated with rapamycin or transforming growth factor-β acquire a regulatory function and suppress T effector lymphocytes
G. Guggino, C. Scottà, G. Lombardi, F. Dieli +1 more
2015Cellular & Molecular Immunology3 citations Open access
Semantic Scholar

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