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L. Santini · SciRah

Researcher profile · Semantic Scholar

L. Santini

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L. Santini — researcher profile on SciRah

h-index: 25
Works: 56
Citations: 5,123

Most-cited papers

Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing.
M. Pizza, V. Scarlato, V. Masignani, M. Giuliani +32 more
2000Science1,376 citations
Semantic Scholar
A universal vaccine for serogroup B meningococcus.
M. Giuliani, J. Adu‐Bobie, M. Comanducci, B. Aricó +26 more
2006Proceedings of the National Academy of Sciences of the United States of America764 citations Open access
Semantic Scholar
Vaccination against Neisseria meningitidis Using Three Variants of the Lipoprotein GNA1870
V. Masignani, M. Comanducci, M. Giuliani, S. Bambini +13 more
2003Journal of Experimental Medicine448 citations Open access
Semantic Scholar
NadA, a Novel Vaccine Candidate of Neisseria meningitidis
M. Comanducci, S. Bambini, B. Brunelli, J. Adu‐Bobie +11 more
2002Journal of Experimental Medicine379 citations Open access
Semantic Scholar
Qualitative and quantitative assessment of meningococcal antigens to evaluate the potential strain coverage of protein-based vaccines
J. Donnelly, D. Medini, G. Boccadifuoco, A. Biolchi +16 more
2010Proceedings of the National Academy of Sciences of the United States of America325 citations Open access
Semantic Scholar
Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans
Davide Serruto, Tiziana Spadafina, Laura Ciucchi, L. Lewis +19 more
2010Proceedings of the National Academy of Sciences of the United States of America237 citations Open access
Semantic Scholar
Previously unrecognized vaccine candidates against group B meningococcus identified by DNA microarrays
R. Grifantini, E. Bartolini, A. Muzzi, M. Draghi +13 more
2002Nature Biotechnology205 citations
Semantic Scholar
Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88
A. Seubert, Samuele Calabro, L. Santini, B. Galli +12 more
2011Proceedings of the National Academy of Sciences of the United States of America200 citations Open access
Semantic Scholar
Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen
E. Malito, A. Faleri, Paola Lo Surdo, D. Veggi +23 more
2013Proceedings of the National Academy of Sciences of the United States of America136 citations Open access
Semantic Scholar
The Region Comprising Amino Acids 100 to 255 of Neisseria meningitidis Lipoprotein GNA 1870 Elicits Bactericidal Antibodies
M. Giuliani, L. Santini, B. Brunelli, A. Biolchi +10 more
2005Infection and Immunity100 citations Open access
Semantic Scholar
Interlaboratory Standardization of the Sandwich Enzyme-Linked Immunosorbent Assay Designed for MATS, a Rapid, Reproducible Method for Estimating the Strain Coverage of Investigational Vaccines
B. Plikaytis, M. Stella, G. Boccadifuoco, L. DeTora +30 more
2012Clinical and Vaccine Immunology68 citations Open access
Semantic Scholar
Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody
E. Malito, Marco Biancucci, A. Faleri, I. Ferlenghi +19 more
2014Proceedings of the National Academy of Sciences of the United States of America66 citations Open access
Semantic Scholar
Development of a glycoconjugate vaccine to prevent meningitis in Africa caused by meningococcal serogroup X
F. Micoli, M. Romano, M. Tontini, E. Cappelletti +16 more
2013Proceedings of the National Academy of Sciences of the United States of America64 citations Open access
Semantic Scholar
Epitope mapping of a bactericidal monoclonal antibody against the factor H binding protein of Neisseria meningitidis.
M. Scarselli, F. Cantini, L. Santini, D. Veggi +10 more
2009Journal of Molecular Biology53 citations
Semantic Scholar
Human protective response induced by meningococcus B vaccine is mediated by the synergy of multiple bactericidal epitopes
M. Giuliani, E. Bartolini, B. Galli, L. Santini +18 more
2018Scientific Reports50 citations Open access
Semantic Scholar
A Novel Mimetic Antigen Eliciting Protective Antibody to Neisseria meningitidis1
D. Granoff, G. Moe, M. Giuliani, J. Adu‐Bobie +9 more
2001Journal of Immunology49 citations Open access
Semantic Scholar
Evidence of Toscana Virus Variants Circulating in Tuscany, Italy, during the Summers of 1995 to 1997
M. Valassina, A. M. Cuppone, S. Bianchi, L. Santini +1 more
1998Journal of Clinical Microbiology45 citations Open access
Semantic Scholar
Two cross‐reactive monoclonal antibodies recognize overlapping epitopes on Neisseria meningitidis factor H binding protein but have different functional properties
A. Faleri, L. Santini, S. Brier, W. Pansegrau +13 more
2014The FASEB Journal38 citations
Semantic Scholar
Laboratory Diagnosis of Toscana Virus Infection by Enzyme Immunoassay with Recombinant Viral Nucleoprotein
D. Soldateschi, G. dal Maso, M. Valassina, L. Santini +2 more
1999Journal of Clinical Microbiology38 citations Open access
Semantic Scholar
Combined Chemical Synthesis and Tailored Enzymatic Elongation Provide Fully Synthetic and Conjugation-Ready Neisseria meningitidis Serogroup X Vaccine Antigens.
D. Oldrini, T. Fiebig, M. Romano, D. Proietti +9 more
2018ACS Chemical Biology37 citations Open access
Semantic Scholar
Recognition of Neisseria meningitidis by the Long Pentraxin PTX3 and Its Role as an Endogenous Adjuvant
B. Bottazzi, L. Santini, S. Savino, M. Giuliani +11 more
2015PLoS ONE35 citations Open access
Semantic Scholar
Intranasal immunization of mice with recombinant Streptococcus gordonii expressing NadA of Neisseria meningitidis induces systemic bactericidal antibodies and local IgA.
Annalisa Ciabattini, Barbara Giomarelli, Riccardo Parigi, Damiana Chiavolini +6 more
2008Vaccine35 citations
Semantic Scholar
Preclinical studies on new proteins as carrier for glycoconjugate vaccines.
M. Tontini, M. R. Romano, D. Proietti, Evita Balducci +6 more
2016Vaccine32 citations Open access
Semantic Scholar
An efficient cell free enzyme-based total synthesis of a meningococcal vaccine candidate
T. Fiebig, M. Romano, D. Oldrini, R. Adamo +7 more
2016npj Vaccines26 citations Open access
Semantic Scholar
Nonfunctional Variant 3 Factor H Binding Proteins as Meningococcal Vaccine Candidates
S. van der Veen, S. Johnson, I. Jongerius, Talat H. Malik +7 more
2013Infection and Immunity25 citations Open access
Semantic Scholar
Rapid detection and typing of circulating mumps virus by reverse transcription/polymerase chain reaction.
M. Cusi, Silvia Bianchi, M. Valassina, L. Santini +2 more
1996Research in Virology24 citations
Semantic Scholar
Exploring host-pathogen interactions through genome wide protein microarray analysis
L. Scietti, K. Sampieri, Irene Pinzuti, E. Bartolini +23 more
2016Scientific Reports23 citations Open access
Semantic Scholar
Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp
J. López-Sagaseta, P. Beernink, F. Bianchi, L. Santini +4 more
2018Nature Communications21 citations Open access
Semantic Scholar
Diagnostic Potential of Toscana Virus N Protein Expressed in Escherichia coli
M. Valassina, D. Soldateschi, G. dal Maso, L. Santini +3 more
1998Journal of Clinical Microbiology21 citations Open access
Semantic Scholar
Reverse vaccinology.
Marirosa Mora, D. Veggi, L. Santini, M. Pizza +1 more
2003Drug Discovery Today20 citations
Semantic Scholar
Nucleotide Sequence at Position 1081 of the Hemagglutinin-Neuraminidase Gene in Wild-Type Strains of Mumps Virus Is the Most Relevant Marker of Virulence
M. Cusi, L. Santini, Silvia Bianchi, M. Valassina +1 more
1998Journal of Clinical Microbiology20 citations Open access
Semantic Scholar
Neisseria meningitidis factor H binding protein bound to monoclonal antibody JAR5: implications for antibody synergy
E. Malito, Paola Lo Surdo, D. Veggi, L. Santini +6 more
2016Biochemical Journal18 citations Open access
Semantic Scholar
Epitope Mapping of a Monoclonal Antibody Directed against Neisserial Heparin Binding Antigen Using Next Generation Sequencing of Antigen-Specific Libraries
M. Domina, Veronica Lanza Cariccio, Salvatore Benfatto, M. Venza +16 more
2016PLoS ONE16 citations Open access
Semantic Scholar
Evaluation of strain coverage of the multicomponent meningococcal serogroup B vaccine (4CMenB) administered in infants according to different immunisation schedules
A. Biolchi, S. Tomei, L. Santini, J. Welsch +7 more
2019Human Vaccines & Immunotherapeutics15 citations Open access
Semantic Scholar
Phage display revisited: Epitope mapping of a monoclonal antibody directed against Neisseria meningitidis adhesin A using the PROFILER technology
V. L. Cariccio, M. Domina, Salvatore Benfatto, M. Venza +17 more
2016mAbs15 citations Open access
Semantic Scholar
Exploiting chimeric human antibodies to characterize a protective epitope of Neisseria adhesin A, one of the Bexsero vaccine components
Isabella Bertoldi, A. Faleri, B. Galli, P. L. Surdo +6 more
2016The FASEB Journal14 citations
Semantic Scholar
Synergic complement‐mediated bactericidal activity of monoclonal antibodies with distinct specificity
E. Natali, Silvia Principato, Francesca Ferlicca, F. Bianchi +12 more
2020The FASEB Journal12 citations Open access
Semantic Scholar
Isolation of human monoclonal antibodies from 4CMenB vaccinees reveals PorB and LOS as the main OMV components inducing cross-strain protection
G. Vezzani, V. Viviani, Martina Audagnotto, Alessandro Rossi +15 more
2025Frontiers in Immunology10 citations Open access
Semantic Scholar
Human monoclonal antibodies targeting subdominant meningococcal antigens confer cross-protection against gonococcus.
Marco Troisi, M. Fabbrini, S. Stazzoni, V. Viviani +43 more
2025Science Translational Medicine9 citations
Semantic Scholar
Elucidating the Structural and Minimal Protective Epitope of the Serogroup X Meningococcal Capsular Polysaccharide
Gian Pietro Pietri, M. Tontini, B. Brogioni, D. Oldrini +18 more
2021Frontiers in Molecular Biosciences8 citations Open access
Semantic Scholar
4CMenB vaccine induces elite cross-protective human antibodies that compete with human factor H for binding to meningococcal fHbp
D. Veggi, F. Bianchi, L. Santini, Paola Lo Surdo +10 more
2020PLoS Pathogens8 citations Open access
Semantic Scholar
Molecular Engineering of Ghfp, the Gonococcal Orthologue of Neisseria meningitidis Factor H Binding Protein
Valentina Rippa, L. Santini, Paola Lo Surdo, F. Cantini +12 more
2015Clinical and Vaccine Immunology8 citations Open access
Semantic Scholar
Peripheral neuropathy associated with anti-myelin basic protein antibodies in a woman vaccinated with rubella virus vaccine.
M. Cusi, S. Bianchi, L. Santini, D. Donati +4 more
1999Journal of Neurovirology8 citations
Semantic Scholar
Cocrystal structure of meningococcal factor H binding protein variant 3 reveals a new crossprotective epitope recognized by human mAb 1E6
F. Bianchi, D. Veggi, L. Santini, F. Buricchi +8 more
2019The FASEB Journal7 citations Open access
Semantic Scholar
Four-component Meningococcal Serogroup B Vaccine Induces Antibodies With Bactericidal Activity Against Diverse Outbreak Strains in Adolescents.
A. Biolchi, S. Tomei, L. Santini, Rita La Gaetana +6 more
2020The Pediatric Infectious Disease Journal5 citations Open access
Semantic Scholar
Antigenic determinants driving serogroup-specific antibody response to Neisseria meningitidis C, W, and Y capsular polysaccharides: Insights for rational vaccine design.
Gian Pietro Pietri, S. Bertuzzi, Katarina Karničar, Luca Unione +13 more
2024Carbohydrate Polymers4 citations Open access
Semantic Scholar
Investigation on the Effect of Immune Selection on Resistance to Bactericidal Antibodies to Group B Meningococci In Vitro
George F. Santos, M. Giuliani, L. Santini, J. Adu-Bobie +4 more
2009Clinical and Vaccine Immunology4 citations Open access
Semantic Scholar
Human monoclonal antibodies reveal subdominant gonococcal and meningococcal cross-protective antigens
Marco Troisi, M. Fabbrini, S. Stazzoni, V. Viviani +42 more
2023bioRxiv2 citations Open access
Semantic Scholar
Cloning and sequencing of the F gene of live attenuated Urabe Am9 mumps virus.
M. Cusi, Silvia Bianchi, M. Valassina, L. Santini +1 more
1995Gene2 citations
Semantic Scholar
Bactericidal antibodies against hypervirulent Neisseria meningitidis C field strains following MenC-CRM or MenACWY-CRM priming and MenACWY-CRM booster in children
M. Giuliani, A. Biolchi, Pavitra Keshavan, M. Moriondo +11 more
2020Human Vaccines & Immunotherapeutics1 citations Open access
Semantic Scholar

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M. Pizza×26
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M. Pizza — researcher profile on SciRah
R. Rappuoli×22
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R. Rappuoli — researcher profile on SciRah
M. Giuliani×20
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M. Giuliani — researcher profile on SciRah
V. Masignani×16
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V. Masignani — researcher profile on SciRah

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S. Savino — researcher profile on SciRah

B. Brunelli×13

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D. Veggi — researcher profile on SciRah

M. Scarselli×9

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M. Scarselli — researcher profile on SciRah

E. Bartolini×8

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E. Bartolini — researcher profile on SciRah

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M. Comanducci — researcher profile on SciRah