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O. Levy · SciRah

Researcher profile · Semantic Scholar

O. Levy

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O. Levy — researcher profile on SciRah

h-index: 10
Works: 26
Citations: 413

Most-cited papers

New Synthetic Technology for Efficient Construction of α-Hydroxy-β-amino Amides via the Passerini Reaction1
J. Semple, T. Owens, and Khanh Nguyen, O. Levy
200095 citations
Semantic Scholar
Discovery of SCH446211 (SCH6): a new ketoamide inhibitor of the HCV NS3 serine protease and HCV subgenomic RNA replication.
Stéphane L. Bogen, A. Arasappan, F. Bennett, Kevin X. Chen +25 more
2006Journal of Medicinal Chemistry49 citations Open access
Semantic Scholar
Novel Exenatide Analogs with Peptidic Albumin Binding Domains: Potent Anti-Diabetic Agents with Extended Duration of Action
O. Levy, C. Jodka, S. Ren, Lala Mamedova +9 more
2014PLoS ONE45 citations Open access
Semantic Scholar
Highly selective mechanism-based thrombin inhibitors: structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes.
R. Krishnan, E. Zhang, K. Håkansson, R. Arni +5 more
1998Biochemistry43 citations
Semantic Scholar
Improved Glucose Control and Reduced Body Weight in Rodents with Dual Mechanism of Action Peptide Hybrids
J. Trevaskis, Christine M. Mack, Cheng-Zao Sun, Christopher J. Soares +12 more
2013PLoS ONE41 citations Open access
Semantic Scholar
A novel long-acting glucose-dependent insulinotropic peptide analogue: enhanced efficacy in normal and diabetic rodents
Krystyna Tatarkiewicz, D. Hargrove, C. Jodka, B. Gedulin +11 more
2013Diabetes, obesity and metabolism32 citations Open access
Semantic Scholar
Potent and selective thrombin inhibitors incorporating the constrained arginine mimic l-3-piperidyl(N-guanidino)alanine at P1.
O. Levy, J. Semple, Michael L. Lim, John E. Reiner +7 more
1996Journal of Medicinal Chemistry30 citations Open access
Semantic Scholar
Hepatitis C virus NS3-4A serine protease inhibitors: SAR of P'2 moiety with improved potency.
A. Arasappan, F. Njoroge, T. Chan, F. Bennett +32 more
2005Bioorganic & Medicinal Chemistry Letters28 citations Open access
Semantic Scholar
Novel, potent and selective chimeric FXa inhibitors featuring hydrophobic P1-ketoamide moieties.
J. Semple, O. Levy, N. K. Minami, T. Owens +1 more
2000Bioorganic & Medicinal Chemistry Letters12 citations Open access
Semantic Scholar
Guanylpiperidine peptidomimetics: potent and selective bis-cation inhibitors of factor Xa.
S. Tamura, O. Levy, T. Uong, John E. Reiner +7 more
2000Bioorganic & Medicinal Chemistry Letters12 citations Open access
Semantic Scholar
New synthetic technology for efficient construction of alpha-hydroxy-beta-amino amides via the Passerini reaction.
J. Semple, T. Owens, K. Nguyen, O. Levy
2000Organic Letters7 citations
Semantic Scholar
A mechanism-based inactivation study of neutral endopeptidase 24.11.
O. Levy, Pascale Taibi, S. Mobashery, S. S. Ghosh
1993Journal of Medicinal Chemistry6 citations Open access
Semantic Scholar
New Synthetic Technology for Efficient Construction of α‐Hydroxy‐β‐amino Amides via the Passerini Reaction.
J. Semple, T. Owens, K. Nguyen, O. Levy
20015 citations
Semantic Scholar
Synthesis & biological evaluation of PYY(3-36) analogs substituted with alanine.
John S Ahn, R. Nazarbaghi, Lawrence J. D'souza, Soumitra S. Ghosh +3 more
2009Advances in Experimental Medicine and Biology4 citations
Semantic Scholar
Exploratory solid-phase synthesis of factor Xa inhibitors: discovery and application of p3-heterocyclic amides as novel types of non-basic arginine surrogates.
Jonathan Z. Ho, O. Levy, Tony S. Gibson, K. Nguyen +1 more
1999Bioorganic & Medicinal Chemistry Letters3 citations Open access
Semantic Scholar
A rational approach for the design of mechanism-based inactivators for zinc proteases
S. S. Ghosh, O. Levy, S. Mobashery
19941 citations
Semantic Scholar
Genetically modified polypeptides having enhanced duration of action
M. Erickson, D. C. Litzinger, Soumitra S. Ghosh, Zijian Guo +7 more
20110 citations
Semantic Scholar
Poster Presentations
O. Levy, Christine M. Mack, Julie Wilson, Jennifer Athanacio +55 more
20080 citations
Semantic Scholar
Hepatitis C Protease NS3-4A serine protease with Ketoamide Inhibitor SCH225724 Bound
A. Arasappan, F. Njoroge, T. Chan, F. Bennett +32 more
20060 citations
Semantic Scholar
family motifs polipetÍdeo pancreatic, polypeptides comprising the same and methods
C. Jodka, D. Parkes, John S Ahn, K. S. Prickett +6 more
20050 citations
Semantic Scholar
Optimization of a continuous assay for obtaining sensitive kinetic data on the inhibition of the HCV NS3 protease
Lim-Wilby Marguerita, S. Anderson, John A. Gaudette, O. Levy +2 more
20020 citations
Semantic Scholar
Peptides as inhibitors of the NS3 serine protease of hepatitis C virus
A. Saksena, V. Girijavallabhan, R. Lovey, E. Jao +24 more
20010 citations
Semantic Scholar
THROMBIN INHIBITORS WITH RIGID TRIPEPTIDYL ALDEHYDES
R. Krishnan, E. Zhang, K. Håkansson, R. Arni +5 more
19990 citations
Semantic Scholar
Stereochemical considerations in drug design: the crystal structures of human α-thrombin complexed with two tripeptidyl aldehyde inhibitors at 2.1 Å resolution
E. Zhang, R. Arni, O. Levy, A. Tulinsky
19960 citations
Semantic Scholar
3-amino-2-oxo-piperidinessigsäurederivate which contain a compound having enzyme-inhibitory effective argininnachahmende
J. Semple, O. Levy, R. Nutt, W. Ripka
19950 citations
Semantic Scholar
A mechanism-based inactivation study of neutral endopeptidase 24.11. [Erratum to document cited in CA119(13):134114z]
O. Levy, Pascale Taibi, S. Mobashery, Soumitra S. Ghosh
19930 citations
Semantic Scholar

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J. Semple — researcher profile on SciRah
Soumitra S. Ghosh×7
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