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M. Schou · SciRah

Researcher profile · Semantic Scholar

M. Schou

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M. Schou — researcher profile on SciRah

h-index: 25
Works: 119
Citations: 2,277

Most-cited papers

Clinical Validation of 18F-AZD4694, an Amyloid-β–Specific PET Radioligand
Z. Cselényi, M. E. Jönhagen, A. Forsberg, C. Halldin +6 more
2012Journal of Nuclear Medicine225 citations Open access
Semantic Scholar
Preclinical Comparison of the Blood–brain barrier Permeability of Osimertinib with Other EGFR TKIs
N. Colclough, Kan Chen, P. Johnström, Nicole Strittmatter +31 more
2020Clinical Cancer Research190 citations Open access
Semantic Scholar
In vitro autoradiography and in vivo evaluation in cynomolgus monkey of [18F]FE‐PE2I, a new dopamine transporter PET radioligand
A. Varrone, C. Steiger, M. Schou, A. Takano +4 more
2009Synapse77 citations
Semantic Scholar
Palladium-Mediated [11C]Carbonylation at Atmospheric Pressure: A General Method Using Xantphos as Supporting Ligand
Kenneth Dahl, M. Schou, N. Amini, C. Halldin
201372 citations
Semantic Scholar
New methodologies for the preparation of carbon-11 labeled radiopharmaceuticals
Kenneth Dahl, C. Halldin, M. Schou
2017Clinical and translational imaging71 citations Open access
Semantic Scholar
Synthesis, radiolabeling and preliminary in vivo evaluation of [18F]FE-PE2I, a new probe for the dopamine transporter.
M. Schou, C. Steiger, A. Varrone, D. Guilloteau +1 more
2009Bioorganic & Medicinal Chemistry Letters56 citations Open access
Semantic Scholar
Brain exposure of the ATM inhibitor AZD1390 in humans - a positron emission tomography (PET) study.
A. Jucaite, P. Stenkrona, Z. Cselényi, S. De Vita +16 more
2020Neuro-Oncology49 citations Open access
Semantic Scholar
Late‐Stage Isotopic Carbon Labeling of Pharmaceutically Relevant Cyclic Ureas Directly from CO2
A. Del Vecchio, F. Caillé, Arnaud Chevalier, O. Loreau +8 more
2018Angewandte Chemie49 citations Open access
Semantic Scholar
A PET study in healthy subjects of brain exposure of 11C-labelled osimertinib – A drug intended for treatment of brain metastases in non-small cell lung cancer
A. Varrone, K. Varnäs, A. Jucaite, Z. Cselényi +8 more
2020Journal of Cerebral Blood Flow and Metabolism48 citations Open access
Semantic Scholar
Preclinical Characterization of AZD9574, a Blood-Brain Barrier Penetrant Inhibitor of PARP1.
Anna D. Staniszewska, Domenic Pilger, Sonja J. Gill, K. Jamal +24 more
2023Clinical Cancer Research46 citations
Semantic Scholar
Sample preparation techniques for radiometabolite analysis of positron emission tomography radioligands; trends, progress, limitations and future prospects
M. Moein, R. Nakao, N. Amini, M. Abdel-Rehim +2 more
2019Trends in Analytical Chemistry (TrAC)41 citations
Semantic Scholar
Large Variation in Brain Exposure of Reference CNS Drugs: a PET Study in Nonhuman Primates
M. Schou, K. Varnäs, S. Lundquist, R. Nakao +5 more
2015International Journal of Neuropsychopharmacology41 citations Open access
Semantic Scholar
Glia Imaging Differentiates Multiple System Atrophy from Parkinson's Disease: A Positron Emission Tomography Study with [11C]PBR28 and Machine Learning Analysis
A. Jucaite, Z. Cselényi, W. Kreisl, E. Rabiner +15 more
2021Movement Disorders35 citations Open access
Semantic Scholar
Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRASG12C with Demonstrable CNS Penetration.
J. Kettle, S. Bagal, D. Barratt, M. Bodnarchuk +41 more
2023Journal of Medicinal Chemistry32 citations Open access
Semantic Scholar
Identification and in vitro characterization of C05-01, a PPB3 derivative with improved affinity for alpha-synuclein.
P. Miranda-Azpiazu, M. Svedberg, M. Higuchi, M. Ono +5 more
2020Brain Research32 citations Open access
Semantic Scholar
Identification of positron emission tomography (PET) tracer candidates by prediction of the target-bound fraction in the brain
M. Fridén, M. Wennerberg, Madeleine Antonsson, Maria Sandberg-Ställ +2 more
2014EJNMMI Research32 citations Open access
Semantic Scholar
An evaluation of a high-pressure (11)CO carbonylation apparatus.
Kenneth Dahl, O. Itsenko, O. Rahman, J. Ulin +5 more
2015Journal of labelled compounds & radiopharmaceuticals28 citations
Semantic Scholar
Visible-Light-Enabled Aminocarbonylation of Unactivated Alkyl Iodides with Stoichiometric Carbon Monoxide for Application on Late-Stage Carbon Isotope Labeling
M. Sardana, Joakim Bergman, Cecilia Ericsson, L. Kingston +4 more
2019Journal of Organic Chemistry26 citations Open access
Semantic Scholar
Identification of PET radiometabolites by cytochrome P450, UHPLC/Q-ToF-MS and fast radio-LC: applied to the PET radioligands [11C]flumazenil, [18F]FE-PE2I, and [11C]PBR28
N. Amini, R. Nakao, M. Schou, C. Halldin
2013Analytical and Bioanalytical Chemistry26 citations
Semantic Scholar
Radiolabeling of a high potency cannabinoid subtype‐1 receptor ligand, N‐(4‐fluoro‐benzyl)‐4‐(3‐(piperidin‐1‐yl)‐indole‐1‐sulfonyl)benzamide (PipISB), with carbon‐11 or fluorine‐18
Sean R. Donohue, C. Halldin, M. Schou, Jinsoo Hong +8 more
200825 citations
Semantic Scholar
Direct plasma metabolite analysis of positron emission tomography radioligands by micellar liquid chromatography with radiometric detection.
R. Nakao, M. Schou, C. Halldin
2012Analytical Chemistry23 citations
Semantic Scholar
[18F]fluoro-benziodoxole: a no-carrier-added electrophilic fluorinating reagent. Rapid, simple radiosynthesis, purification and application for fluorine-18 labelling.
Miguel A. Cortés González, P. Nordeman, Antonio Bermejo Gómez, Denise N Meyer +3 more
2018Chemical Communications22 citations Open access
Semantic Scholar
Synthesis and evaluation of pyridylbenzofuran, pyridylbenzothiazole and pyridylbenzoxazole derivatives as ¹⁸F-PET imaging agents for β-amyloid plaques.
B. Swahn, J. Sandell, D. Pyring, Margareta Bergh +6 more
2012Bioorganic & Medicinal Chemistry Letters22 citations Open access
Semantic Scholar
Low background and high contrast PET imaging of amyloid-β with [11C]AZD2995 and [11C]AZD2184 in Alzheimer’s disease patients
A. Forsberg, A. Juréus, Z. Cselényi, M. Eriksdotter +12 more
2013European Journal of Nuclear Medicine and Molecular Imaging21 citations Open access
Semantic Scholar
The development of a GPR44 targeting radioligand [11C]AZ12204657 for in vivo assessment of beta cell mass
M. Jahan, P. Johnström, R. Selvaraju, M. Svedberg +11 more
2018EJNMMI Research19 citations Open access
Semantic Scholar
11C-carbonylation reactions using gas–liquid segmented microfluidics
Kenneth Dahl, M. Schou, J. Ulin, Carl-Olof Sjöberg +2 more
201518 citations Open access
Semantic Scholar
Determination of plasma protein binding of positron emission tomography radioligands by high-performance frontal analysis.
N. Amini, R. Nakao, M. Schou, C. Halldin
2014Journal of Pharmaceutical and Biomedical Analysis18 citations
Semantic Scholar
Identification of Novel, Selective Ataxia-Telangiectasia Mutated Kinase Inhibitors with the Ability to Penetrate the Blood-Brain Barrier: The Discovery of AZD1390.
K. Pike, T. Hunt, B. Barlaam, David Benstead +22 more
2024Journal of Medicinal Chemistry17 citations Open access
Semantic Scholar
Improved Yields for the Palladium-Mediated 11C-Carbonylation Reaction Using Microwave Technology
Kenneth Dahl, M. Schou, O. Rahman, C. Halldin
201417 citations
Semantic Scholar
Development of radioligands for imaging of brain norepinephrine transporters in vivo with positron emission tomography.
M. Schou, V. Pike, C. Halldin
2007Current Topics in Medicinal Chemistry17 citations
Semantic Scholar
Radiolabeling of the cannabinoid receptor agonist AZD1940 with carbon-11 and PET microdosing in non-human primate.
M. Schou, K. Varnäs, A. Jucaite, B. Gulyás +2 more
2013Nuclear Medicine and Biology16 citations
Semantic Scholar
Radiofluorination and reductive amination using a microfluidic device
Kenneth Dahl, M. Schou, C. Halldin
201216 citations
Semantic Scholar
First radiolabeling of a ganglioside with a positron emitting radionuclide - in vivo PET demonstrates low exposure of radiofluorinated GM1 in non-human primate brain.
Evgeny V. Revunov, P. Johnström, R. Arakawa, J. Malmquist +4 more
2020ACS Chemical Neuroscience14 citations
Semantic Scholar
Synthesis, Radiolabeling, and In Vivo Pharmacokinetic Evaluation of the Amyloid Beta Radioligand [11C]AZD4694 in Nonhuman Primates
M. Schou, K. Varnäs, J. Sandell, P. Johnström +10 more
2014Molecular Imaging and Biology13 citations
Semantic Scholar
“In‐loop” carbonylation—A simplified method for carbon‐11 labelling of drugs and radioligands
Mélodie Ferrat, Kenneth Dahl, C. Halldin, M. Schou
2020Journal of labelled compounds & radiopharmaceuticals12 citations Open access
Semantic Scholar
Rapid and Efficient Synthesis of 11 C-Labeled Benzimidazolones Using [11 C]Carbon Dioxide
Kaisa Horkka, Kenneth Dahl, J. Bergare, C. Elmore +2 more
2019ChemistrySelect12 citations Open access
Semantic Scholar
Rapid metabolite analysis of positron emission tomography radioligands by direct plasma injection combining micellar cleanup with high submicellar liquid chromatography with radiometric detection.
R. Nakao, M. Schou, C. Halldin
2012Journal of Chromatography A12 citations
Semantic Scholar
Investigation of the Metabolites of (S,S)-[11C] MeNER in Humans, Monkeys and Rats
M. Schou, Sami S. Zoghbi, H. U. Shetty, E. Shchukin +8 more
2008Molecular Imaging and Biology12 citations Open access
Semantic Scholar
Synthesis and preclinical evaluation of 6-[18F]Fluorine-Alpha-Methyl-L-Tryptophan, a novel PET tracer for measuring tryptophan uptake.
R. Krasikova, M. Kondrashov, C. Avagliano, M. Petukhov +9 more
2020ACS Chemical Neuroscience11 citations
Semantic Scholar
Pulmonary PET imaging confirms preferential lung target occupancy of an inhaled bronchodilator
M. Schou, P. Ewing, Z. Cselényi, M. Fridén +3 more
2019EJNMMI Research11 citations Open access
Semantic Scholar
Abstract CT013: Osimertinib displays high brain exposure in healthy subjects with intact blood-brain barrier: a microdose positron emission tomography (PET) study with11C-labelled osimertinib
K. Vishwanathan, A. Varrone, Katarina Varnas, A. Jucaite +8 more
2018Clinical Trials11 citations
Semantic Scholar
A two-step one-pot radiosynthesis of the potent dopamine D2/D3 agonist PET radioligand [11C]MNPA
C. Steiger, S. Finnema, Liina Raus, M. Schou +5 more
200911 citations
Semantic Scholar
Reduction of [11 C]CO2 to [11 C]CO using solid supported zinc.
Kenneth Dahl, J. Ulin, M. Schou, C. Halldin
2017Journal of labelled compounds & radiopharmaceuticals10 citations
Semantic Scholar
Synthesis of a delta opioid agonist in [2H6], [2H4], [11C], and [14C] labeled forms
C. Elmore, Kelly Brush, M. Schou, W. Palmer +7 more
201110 citations
Semantic Scholar
Increased Brain Exposure of an Alpha-Synuclein Fibrillization Modulator by Utilization of an Activated Ester Prodrug Strategy.
A. G. Cairns, A. Vázquez-Romero, Mohammad Mahdi Moein, Jörgen Ådén +6 more
2018ACS Chemical Neuroscience9 citations
Semantic Scholar
Development of [ Carbonyl-11C]AZ13198083, a Novel Histamine Type-3 Receptor Radioligand with Favorable Kinetics.
Kenneth Dahl, R. Nakao, N. Amini, M. Moein +4 more
2018ACS Chemical Neuroscience9 citations
Semantic Scholar
[11C]AZ10419096 - a full antagonist PET radioligand for imaging brain 5-HT1B receptors.
Anton Lindberg, S. Nag, M. Schou, A. Takano +6 more
2017Nuclear Medicine and Biology9 citations
Semantic Scholar
Efficient DBU accelerated synthesis of 18F-labelled trifluoroacetamides.
A. Gómez, Miguel A. Cortés González, Marvin Lübcke, Magnus J. Johansson +3 more
2016Chemical Communications9 citations Open access
Semantic Scholar
Discovery of a Novel Muscarinic Receptor PET Radioligand with Rapid Kinetics in the Monkey Brain.
J. Malmquist, K. Varnäs, M. Svedberg, F. Vallée +3 more
2017ACS Chemical Neuroscience8 citations Open access
Semantic Scholar
Direct and Efficient (Carbonyl)cobalt‐Mediated Aryl Acetylation Using [11C]Methyl Iodide
Kenneth Dahl, M. Schou, C. Halldin
20168 citations
Semantic Scholar

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