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A. Varrone · SciRah

Researcher profile · Semantic Scholar

A. Varrone

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A. Varrone — researcher profile on SciRah

h-index: 53
Works: 257
Citations: 9,934

Most-cited papers

Strategic roadmap for an early diagnosis of Alzheimer's disease based on biomarkers.
G. Frisoni, M. Boccardi, F. Barkhof, K. Blennow +44 more
2017Lancet Neurology579 citations Open access
Semantic Scholar
EANM procedure guidelines for brain PET imaging using [18F]FDG, version 3
E. Guedj, A. Varrone, R. Boellaard, N. Albert +14 more
2021European Journal of Nuclear Medicine and Molecular Imaging288 citations Open access
Semantic Scholar
EANM practice guideline/SNMMI procedure standard for dopaminergic imaging in Parkinsonian syndromes 1.0
S. Morbelli, G. Esposito, J. Arbizu, H. Barthel +24 more
2020European Journal of Nuclear Medicine and Molecular Imaging231 citations Open access
Semantic Scholar
Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington’s disease
B. Zeitler, Steven Froelich, Kimberly Marlen, David A. Shivak +47 more
2019Nature Medicine171 citations
Semantic Scholar
Effects of age, BMI and sex on the glial cell marker TSPO — a multicentre [11C]PBR28 HRRT PET study
J. Tuisku, P. Plavén-Sigray, Edward Gaiser, L. Airas +33 more
2019bioRxiv107 citations Open access
Semantic Scholar
Phosphodiesterase 10A Inhibition Improves Cortico-Basal Ganglia Function in Huntington's Disease Models.
V. Beaumont, S. Zhong, Hai Lin, Wenjin Xu +29 more
2016Neuron106 citations Open access
Semantic Scholar
The Immune Response of the Human Brain to Abdominal Surgery
A. Forsberg, S. Cervenka, M. J. Fagerlund, L. Rasmussen +16 more
2017Annals of Neurology105 citations Open access
Semantic Scholar
Nigrostriatal dopamine transporter availability in early Parkinson's disease
P. Fazio, P. Svenningsson, Z. Cselényi, C. Halldin +2 more
2018Movement Disorders100 citations
Semantic Scholar
Clinical validity of brain fluorodeoxyglucose positron emission tomography as a biomarker for Alzheimer's disease in the context of a structured 5-phase development framework.
V. Garibotto, K. Herholz, M. Boccardi, A. Picco +4 more
2017Neurobiology of Aging88 citations Open access
Semantic Scholar
Dopamine transporter imaging with [18F]FE-PE2I PET and [123I]FP-CIT SPECT—a clinical comparison
Susanna Jakobson Mo, J. Axelsson, L. Jonasson, A. Larsson +8 more
2018EJNMMI Research76 citations Open access
Semantic Scholar
In Vivo and In Vitro Characterization of a Novel MAO-B Inhibitor Radioligand, 18F-Labeled Deuterated Fluorodeprenyl
S. Nag, P. Fazio, L. Lehmann, G. Kettschau +9 more
2016Journal of Nuclear Medicine72 citations Open access
Semantic Scholar
Clinical validity of increased cortical uptake of amyloid ligands on PET as a biomarker for Alzheimer's disease in the context of a structured 5-phase development framework.
K. Chiotis, L. Saint-Aubert, M. Boccardi, A. Gietl +9 more
2017Neurobiology of Aging68 citations Open access
Semantic Scholar
In vivo evidence of a functional association between immune cells in blood and brain in healthy human subjects.
N. Kanegawa, K. Collste, A. Forsberg, M. Schain +10 more
2016Brain, behavior, and immunity56 citations Open access
Semantic Scholar
PET imaging of [11C]PBR28 in Parkinson’s disease patients does not indicate increased binding to TSPO despite reduced dopamine transporter binding
K. Varnäs, Z. Cselényi, A. Jucaite, C. Halldin +3 more
2018European Journal of Nuclear Medicine and Molecular Imaging55 citations Open access
Semantic Scholar
[123I]FP-CIT ENC-DAT normal database: the impact of the reconstruction and quantification methods
L. Tossici-Bolt, J. Dickson, T. Séra, J. Booij +11 more
2017EJNMMI Physics51 citations Open access
Semantic Scholar
Brain exposure of the ATM inhibitor AZD1390 in humans - a positron emission tomography (PET) study.
A. Jucaite, P. Stenkrona, Z. Cselényi, S. De Vita +16 more
2020Neuro-Oncology49 citations Open access
Semantic Scholar
A PET study in healthy subjects of brain exposure of 11C-labelled osimertinib – A drug intended for treatment of brain metastases in non-small cell lung cancer
A. Varrone, K. Varnäs, A. Jucaite, Z. Cselényi +8 more
2020Journal of Cerebral Blood Flow and Metabolism48 citations Open access
Semantic Scholar
Implementation of the European multicentre database of healthy controls for [123I]FP-CIT SPECT increases diagnostic accuracy in patients with clinically uncertain parkinsonian syndromes
N. Albert, M. Unterrainer, M. Diemling, G. Xiong +20 more
2016European Journal of Nuclear Medicine and Molecular Imaging44 citations Open access
Semantic Scholar
Guidelines to PET measurements of the target occupancy in the brain for drug development
A. Takano, A. Varrone, B. Gulyás, P. Salvadori +6 more
2016European Journal of Nuclear Medicine and Molecular Imaging39 citations Open access
Semantic Scholar
Dual tracer tau PET imaging reveals different molecular targets for 11C-THK5351 and 11C-PBB3 in the Alzheimer brain
K. Chiotis, P. Stenkrona, O. Almkvist, V. Stepanov +10 more
2018European Journal of Nuclear Medicine and Molecular Imaging38 citations Open access
Semantic Scholar
Reduction in camera-specific variability in [123I]FP-CIT SPECT outcome measures by image reconstruction optimized for multisite settings: impact on age-dependence of the specific binding ratio in the ENC-DAT database of healthy controls
R. Buchert, A. Kluge, L. Tossici-Bolt, J. Dickson +16 more
2016European Journal of Nuclear Medicine and Molecular Imaging36 citations Open access
Semantic Scholar
Glia Imaging Differentiates Multiple System Atrophy from Parkinson's Disease: A Positron Emission Tomography Study with [11C]PBR28 and Machine Learning Analysis
A. Jucaite, Z. Cselényi, W. Kreisl, E. Rabiner +15 more
2021Movement Disorders35 citations Open access
Semantic Scholar
Identification and in vitro characterization of C05-01, a PPB3 derivative with improved affinity for alpha-synuclein.
P. Miranda-Azpiazu, M. Svedberg, M. Higuchi, M. Ono +5 more
2020Brain Research32 citations Open access
Semantic Scholar
Performance Evaluation of a High-Resolution Nonhuman Primate PET/CT System
Zsolt Sarnyai, K. Nagy, G. Patay, M. Molnár +7 more
2019Journal of Nuclear Medicine32 citations Open access
Semantic Scholar
Assessment of simplified ratio-based approaches for quantification of PET [11C]PBR28 data
G. Matheson, P. Plavén-Sigray, A. Forsberg, A. Varrone +2 more
2017EJNMMI Research32 citations Open access
Semantic Scholar
Clinical validity of presynaptic dopaminergic imaging with 123I-ioflupane and noradrenergic imaging with 123I-MIBG in the differential diagnosis between Alzheimer's disease and dementia with Lewy bodies in the context of a structured 5-phase development framework.
I. Sonni, O. Ratib, M. Boccardi, A. Picco +3 more
2017Neurobiology of Aging32 citations
Semantic Scholar
Intraputamenal Cerebral Dopamine Neurotrophic Factor in Parkinson's Disease: A Randomized, Double‐Blind, Multicenter Phase 1 Trial
H. Huttunen, Sigrid Booms, M. Sjögren, V. Kerstens +30 more
2023Movement Disorders31 citations Open access
Semantic Scholar
Low serotonin1B receptor binding potential in the anterior cingulate cortex in drug-free patients with recurrent major depressive disorder.
M. Tiger, L. Farde, C. Rück, A. Varrone +4 more
2016Psychiatry research. Neuroimaging31 citations Open access
Semantic Scholar
PET Molecular Imaging of Phosphodiesterase 10A: An Early Biomarker of Huntington's Disease Progression
P. Fazio, C. Fitzer-Attas, L. Mrzljak, J. Bronzova +11 more
2020Movement Disorders30 citations
Semantic Scholar
Patterns of age related changes for phosphodiesterase type‐10A in comparison with dopamine D2/3 receptors and sub‐cortical volumes in the human basal ganglia: A PET study with 18F‐MNI‐659 and 11C‐raclopride with correction for partial volume effect
P. Fazio, M. Schain, L. Mrzljak, N. Amini +8 more
2017NeuroImage26 citations
Semantic Scholar
Optimal Acquisition Time Window and Simplified Quantification of Dopamine Transporter Availability Using 18F-FE-PE2I in Healthy Controls and Parkinson Disease Patients
I. Sonni, P. Fazio, M. Schain, C. Halldin +3 more
2016Journal of Nuclear Medicine26 citations
Semantic Scholar
In vivo measurement of PDE10A enzyme occupancy by positron emission tomography (PET) following single oral dose administration of PF‐02545920 in healthy male subjects
M. Delnomdedieu, A. Forsberg, A. Ogden, P. Fazio +10 more
2017Neuropharmacology25 citations
Semantic Scholar
Mapping the distribution of serotonin transporter in the human brainstem with high-resolution PET: Validation using postmortem autoradiography data
P. Fazio, M. Schain, K. Varnäs, C. Halldin +2 more
2016NeuroImage25 citations
Semantic Scholar
[11C]CHDI-626, a PET Tracer Candidate for Imaging Mutant Huntingtin Aggregates with Reduced Binding to AD Pathological Proteins.
Long-Bin Liu, Peter D. Johnson, Michael E. Prime, V. Khetarpal +38 more
2021Journal of Medicinal Chemistry24 citations
Semantic Scholar
Positron emission tomography measurement of brain MAO-B inhibition in patients with Alzheimer’s disease and elderly controls after oral administration of sembragiline
S. Sturm, A. Forsberg, S. Nave, P. Stenkrona +12 more
2016European Journal of Nuclear Medicine and Molecular Imaging24 citations Open access
Semantic Scholar
High-resolution PET imaging reveals subtle impairment of the serotonin transporter in an early non-depressed Parkinson’s disease cohort
P. Fazio, D. Ferreira, P. Svenningsson, C. Halldin +3 more
2020European Journal of Nuclear Medicine and Molecular Imaging23 citations Open access
Semantic Scholar
Accuracy and reliability of [11C]PBR28 specific binding estimated without the use of a reference region
P. Plavén-Sigray, M. Schain, F. Zanderigo, L. Farde +14 more
2018bioRxiv23 citations Open access
Semantic Scholar
The impact of reconstruction and scanner characterisation on the diagnostic capability of a normal database for [123I]FP-CIT SPECT imaging
J. Dickson, L. Tossici-Bolt, T. Séra, J. Booij +11 more
2017EJNMMI Research23 citations Open access
Semantic Scholar
COVID-19 and the brain: impact on nuclear medicine in neurology
S. Morbelli, O. Ekmekcioglu, H. Barthel, N. Albert +11 more
2020European Journal of Nuclear Medicine and Molecular Imaging22 citations Open access
Semantic Scholar
Dopamine transporter imaging in neurodegenerative movement disorders: PET vs. SPECT
V. Kerstens, A. Varrone
2020Clinical and translational imaging22 citations Open access
Semantic Scholar
Longitudinal Small-Animal PET Imaging of the zQ175 Mouse Model of Huntington Disease Shows In Vivo Changes of Molecular Targets in the Striatum and Cerebral Cortex
J. Häggkvist, Miklós Tóth, L. Tari, K. Varnäs +10 more
2017Journal of Nuclear Medicine22 citations Open access
Semantic Scholar
Novel Imaging Biomarkers for Huntington’s Disease and Other Hereditary Choreas
P. Fazio, M. Paucar, P. Svenningsson, A. Varrone
2018Current Neurology and Neuroscience Reports20 citations Open access
Semantic Scholar
PET as a Translational Tool in Drug Development for Neuroscience Compounds
A. Varrone, C. Bundgaard, B. Bang-Andersen
2022Clinical pharmacology and therapy19 citations Open access
Semantic Scholar
Spinocerebellar ataxia type 4 is caused by a GGC expansion in the ZFHX3 gene and is associated with prominent dysautonomia and motor neuron signs
M. Paucar, D. Nilsson, M. Engvall, J. Laffita-Mesa +13 more
2024Journal of Internal Medicine17 citations Open access
Semantic Scholar
[18F]FE-PE2I DAT correlates with Parkinson’s disease duration, stage, and rigidity/bradykinesia scores: a PET radioligand validation study
V. Kerstens, P. Fazio, M. Sundgren, C. Halldin +2 more
2023EJNMMI Research16 citations Open access
Semantic Scholar
Characterization of the Novel P2X7 Receptor Radioligand [3H]JNJ-64413739 in Human Brain Tissue
Jens D Mikkelsen, Sanjay S. Aripaka, Sif G. Kaad, B. A. Pazarlar +5 more
2022ACS Chemical Neuroscience15 citations Open access
Semantic Scholar
Molecular imaging of neuroinflammation in Alzheimer’s disease
A. Varrone, A. Nordberg
2015Clinical and translational imaging15 citations Open access
Semantic Scholar
First-in-Human Evaluation of 18F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B
Y. Wakabayashi, P. Stenkrona, R. Arakawa, Xue-Feng Yan +21 more
2022Journal of Nuclear Medicine14 citations Open access
Semantic Scholar
Simplified quantification of [18F]FE-PE2I PET in Parkinson’s disease: Discriminative power, test–retest reliability and longitudinal validity during early peak and late pseudo-equilibrium
J. Brumberg, V. Kerstens, Z. Cselényi, P. Svenningsson +3 more
2020Journal of Cerebral Blood Flow and Metabolism14 citations Open access
Semantic Scholar
Whole-Body Biodistribution and Dosimetry of the Dopamine Transporter Radioligand 18F-FE-PE2I in Human Subjects
Helena Lizana, L. Johansson, J. Axelsson, A. Larsson +5 more
2018Journal of Nuclear Medicine14 citations Open access
Semantic Scholar

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C. Halldin×27
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C. Halldin — researcher profile on SciRah
L. Farde×14
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P. Fazio×13
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A. Forsberg×10
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P. Svenningsson

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A. Jucaite — researcher profile on SciRah

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F. Nobili — researcher profile on SciRah

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