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L. Farde · SciRah

Researcher profile · Semantic Scholar

L. Farde

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L. Farde — researcher profile on SciRah

h-index: 96
Works: 621
Citations: 34K

Most-cited papers

Cortical brain abnormalities in 4474 individuals with schizophrenia and 5098 controls via the ENIGMA consortium
T. V. van Erp, E. Walton, D. Hibar, L. Schmaal +185 more
2018Biological Psychiatry839 citations Open access
Semantic Scholar
Preclinical Comparison of the Blood–brain barrier Permeability of Osimertinib with Other EGFR TKIs
N. Colclough, Kan Chen, P. Johnström, Nicole Strittmatter +31 more
2020Clinical Cancer Research190 citations Open access
Semantic Scholar
Effects of age, BMI and sex on the glial cell marker TSPO — a multicentre [11C]PBR28 HRRT PET study
J. Tuisku, P. Plavén-Sigray, Edward Gaiser, L. Airas +33 more
2019bioRxiv107 citations Open access
Semantic Scholar
Lower levels of the glial cell marker TSPO in drug-naive first-episode psychosis patients as measured using PET and [11C]PBR28
K. Collste, P. Plavén-Sigray, H. Fatouros-Bergman, P. Victorsson +9 more
2017Molecular Psychiatry107 citations Open access
Semantic Scholar
The Immune Response of the Human Brain to Abdominal Surgery
A. Forsberg, S. Cervenka, M. J. Fagerlund, L. Rasmussen +16 more
2017Annals of Neurology105 citations Open access
Semantic Scholar
Nigrostriatal dopamine transporter availability in early Parkinson's disease
P. Fazio, P. Svenningsson, Z. Cselényi, C. Halldin +2 more
2018Movement Disorders100 citations
Semantic Scholar
Brain Age Prediction Reveals Aberrant Brain White Matter in Schizophrenia and Bipolar Disorder: A Multisample Diffusion Tensor Imaging Study.
S. Tønnesen, T. Kaufmann, A. D. de Lange, Geneviève Richard +44 more
2020Biological Psychiatry: Cognitive Neuroscience and Neuroimaging65 citations Open access
Semantic Scholar
GABAA receptor availability is not altered in adults with autism spectrum disorder or in mouse models
J. Horder, M. Andersson, M. Mendez, Nisha Singh +19 more
2018Science Translational Medicine56 citations Open access
Semantic Scholar
PET imaging of [11C]PBR28 in Parkinson’s disease patients does not indicate increased binding to TSPO despite reduced dopamine transporter binding
K. Varnäs, Z. Cselényi, A. Jucaite, C. Halldin +3 more
2018European Journal of Nuclear Medicine and Molecular Imaging55 citations Open access
Semantic Scholar
Brain exposure of the ATM inhibitor AZD1390 in humans - a positron emission tomography (PET) study.
A. Jucaite, P. Stenkrona, Z. Cselényi, S. De Vita +16 more
2020Neuro-Oncology49 citations Open access
Semantic Scholar
A PET study in healthy subjects of brain exposure of 11C-labelled osimertinib – A drug intended for treatment of brain metastases in non-small cell lung cancer
A. Varrone, K. Varnäs, A. Jucaite, Z. Cselényi +8 more
2020Journal of Cerebral Blood Flow and Metabolism48 citations Open access
Semantic Scholar
Serotonin transporter availability in adults with autism—a positron emission tomography study
M. Andersson, Ä. Tangen, L. Farde, S. Bölte +3 more
2020Molecular Psychiatry48 citations Open access
Semantic Scholar
Validity and reliability of extrastriatal [11C]raclopride binding quantification in the living human brain
J. Svensson, M. Schain, P. Plavén-Sigray, S. Cervenka +5 more
2019bioRxiv44 citations Open access
Semantic Scholar
The genetic architecture of human brainstem structures and their involvement in common brain disorders
T. Elvsåshagen, S. Bahrami, D. van der Meer, I. Agartz +87 more
2019Nature Communications43 citations Open access
Semantic Scholar
Glia Imaging Differentiates Multiple System Atrophy from Parkinson's Disease: A Positron Emission Tomography Study with [11C]PBR28 and Machine Learning Analysis
A. Jucaite, Z. Cselényi, W. Kreisl, E. Rabiner +15 more
2021Movement Disorders35 citations Open access
Semantic Scholar
Increased number of monocytes and plasma levels of MCP‐1 and YKL‐40 in first‐episode psychosis
F. Orhan, L. Schwieler, H. Fatouros-Bergman, A. Malmqvist +8 more
2018Acta Psychiatrica Scandinavica34 citations
Semantic Scholar
Assessment of simplified ratio-based approaches for quantification of PET [11C]PBR28 data
G. Matheson, P. Plavén-Sigray, A. Forsberg, A. Varrone +2 more
2017EJNMMI Research32 citations Open access
Semantic Scholar
GABAA receptor occupancy by subtype selective GABAAα2,3 modulators: PET studies in humans
A. Jucaite, Z. Cselényi, J. Lappalainen, D. McCarthy +7 more
2016Psychopharmacology32 citations Open access
Semantic Scholar
Low serotonin1B receptor binding potential in the anterior cingulate cortex in drug-free patients with recurrent major depressive disorder.
M. Tiger, L. Farde, C. Rück, A. Varrone +4 more
2016Psychiatry research. Neuroimaging31 citations Open access
Semantic Scholar
Thalamic dopamine D2-receptor availability in schizophrenia: a study on antipsychotic-naive patients with first-episode psychosis and a meta-analysis
P. Plavén-Sigray, Pauliina Ikonen Victorsson, A. Santillo, G. Matheson +9 more
2021Molecular Psychiatry29 citations Open access
Semantic Scholar
The MINDVIEW project: First results
J. Benlloch, Antonio J. González, R. Pani, Enrico Preziosi +16 more
2018European psychiatry28 citations Open access
Semantic Scholar
Disease activity in rheumatoid arthritis is inversely related to cerebral TSPO binding assessed by [11C]PBR28 positron emission tomography.
A. Forsberg, J. Lampa, J. Estelius, S. Cervenka +5 more
2019Journal of Neuroimmunology26 citations Open access
Semantic Scholar
D1-Dopamine Receptor Availability in First-Episode Neuroleptic Naive Psychosis Patients
P. Stenkrona, G. Matheson, C. Halldin, S. Cervenka +1 more
2019International Journal of Neuropsychopharmacology26 citations Open access
Semantic Scholar
Brain neuroreceptor density and personality traits: towards dimensional biomarkers for psychiatric disorders
L. Farde, P. Plavén-Sigray, J. Borg, S. Cervenka
2018Philosophical Transactions of the Royal Society B: Biological Sciences26 citations Open access
Semantic Scholar
Fenfluramine Reduces [11C]Cimbi-36 Binding to the 5-HT2A Receptor in the Nonhuman Primate Brain
Kai-Chun Yang, V. Stepanov, S. Martinsson, A. Ettrup +5 more
2017International Journal of Neuropsychopharmacology26 citations Open access
Semantic Scholar
Test-retest reliability and convergent validity of (R)-[11C]PK11195 outcome measures without arterial input function
P. Plavén-Sigray, G. Matheson, Z. Cselényi, A. Jucaite +2 more
2018bioRxiv25 citations Open access
Semantic Scholar
Mapping the distribution of serotonin transporter in the human brainstem with high-resolution PET: Validation using postmortem autoradiography data
P. Fazio, M. Schain, K. Varnäs, C. Halldin +2 more
2016NeuroImage25 citations
Semantic Scholar
High-resolution PET imaging reveals subtle impairment of the serotonin transporter in an early non-depressed Parkinson’s disease cohort
P. Fazio, D. Ferreira, P. Svenningsson, C. Halldin +3 more
2020European Journal of Nuclear Medicine and Molecular Imaging23 citations Open access
Semantic Scholar
Accuracy and reliability of [11C]PBR28 specific binding estimated without the use of a reference region
P. Plavén-Sigray, M. Schain, F. Zanderigo, L. Farde +14 more
2018bioRxiv23 citations Open access
Semantic Scholar
Kinfitr — an open-source tool for reproducible PET modelling: validation and evaluation of test-retest reliability
J. Tjerkaski, S. Cervenka, L. Farde, G. Matheson
2020bioRxiv22 citations Open access
Semantic Scholar
Reliability of volumetric and surface‐based normalisation and smoothing techniques for PET analysis of the cortex: A test‐retest analysis using [11C]SCH‐23390
G. Matheson, P. Stenkrona, Z. Cselényi, P. Plavén-Sigray +3 more
2017NeuroImage22 citations Open access
Semantic Scholar
The development of a GPR44 targeting radioligand [11C]AZ12204657 for in vivo assessment of beta cell mass
M. Jahan, P. Johnström, R. Selvaraju, M. Svedberg +11 more
2018EJNMMI Research19 citations Open access
Semantic Scholar
Serotonin concentration enhancers at clinically relevant doses reduce [11C]AZ10419369 binding to the 5-HT1B receptors in the nonhuman primate brain
Kai-Chun Yang, A. Takano, C. Halldin, L. Farde +1 more
2018Translational Psychiatry18 citations Open access
Semantic Scholar
Differential Effect of APOE Alleles on Brain Glucose Metabolism in Targeted Replacement Mice: An [18F]FDG-μPET Study
M. Venzi, Miklós Tóth, J. Häggkvist, A. Bogstedt +4 more
2017Journal of Alzheimer's disease reports18 citations Open access
Semantic Scholar
CSF dopamine is elevated in first-episode psychosis and associates to symptom severity and cognitive performance.
F. Orhan, M. Goiny, Meneca Becklén, Levida Mathé +8 more
2023Schizophrenia Research16 citations Open access
Semantic Scholar
Low convergent validity of [11C]raclopride binding in extrastriatal brain regions: a PET study of within-subject correlations with [11C]FLB 457
Tove Freiburghaus, J. Svensson, G. Matheson, P. Plavén-Sigray +3 more
2020bioRxiv16 citations Open access
Semantic Scholar
The pro-psychotic metabotropic glutamate receptor compounds fenobam and AZD9272 share binding sites with monoamine oxidase-B inhibitors in humans.
K. Varnäs, Z. Cselényi, R. Arakawa, S. Nag +7 more
2020Neuropharmacology15 citations Open access
Semantic Scholar
[11C]raclopride positron emission tomography study of dopamine‐D2/3 receptor binding in patients with severe major depressive episodes before and after electroconvulsive therapy and compared to control subjects
M. Tiger, J. Svensson, B. Liberg, Tomoyuki Saijo +4 more
2020Psychiatry and Clinical Neurosciences14 citations Open access
Semantic Scholar
Decreased 5‐HT1A binding in mild Alzheimer's disease—A positron emission tomography study
Patrik Mattsson, Z. Cselényi, B. Andrée, J. Borg +3 more
2022Synapse13 citations Open access
Semantic Scholar
The metabotropic glutamate receptor 5 radioligand [11C]AZD9272 identifies unique binding sites in primate brain
K. Varnäs, A. Juréus, S. Finnema, P. Johnström +6 more
2018Neuropharmacology13 citations Open access
Semantic Scholar
Effect of clinically relevant doses of vortioxetine and citalopram on serotonergic PET markers in the nonhuman primate brain
Kai-Chun Yang, V. Stepanov, N. Amini, S. Martinsson +7 more
2019Neuropsychopharmacology12 citations Open access
Semantic Scholar
Contribution of non-genetic factors to dopamine and serotonin receptor availability in the adult human brain
J. Borg, S. Cervenka, R. Kuja-Halkola, G. Matheson +8 more
2016Molecular Psychiatry12 citations Open access
Semantic Scholar
Effects of sevoflurane anaesthesia on radioligand binding to monoamine oxidase-B in vivo
K. Varnäs, S. Finnema, P. Johnström, R. Arakawa +3 more
2020British Journal of Anaesthesia11 citations Open access
Semantic Scholar
Pulmonary PET imaging confirms preferential lung target occupancy of an inhaled bronchodilator
M. Schou, P. Ewing, Z. Cselényi, M. Fridén +3 more
2019EJNMMI Research11 citations Open access
Semantic Scholar
Abstract CT013: Osimertinib displays high brain exposure in healthy subjects with intact blood-brain barrier: a microdose positron emission tomography (PET) study with11C-labelled osimertinib
K. Vishwanathan, A. Varrone, Katarina Varnas, A. Jucaite +8 more
2018Clinical Trials11 citations
Semantic Scholar
[11C]SCH23390 binding to the D1-dopamine receptor in the human brain—a comparison of manual and automated methods for image analysis
P. Stenkrona, G. Matheson, S. Cervenka, Pontus Plavén Sigray +2 more
2018EJNMMI Research10 citations Open access
Semantic Scholar
Striatal dopamine D2 receptor availability as a predictor of subsequent alcohol use in social drinkers.
Simon Jangard, N. Jayaram-Lindström, N. Isacsson, G. Matheson +5 more
2023Addiction9 citations Open access
Semantic Scholar
Synthesis and Autoradiography of Novel F-18 Labeled Reversible Radioligands for Detection of Monoamine Oxidase B
S. Nag, Zhisheng Jia, M. Svedberg, A. Jackson +5 more
2020ACS Chemical Neuroscience9 citations Open access
Semantic Scholar
Cerebrospinal fluid levels of sphingolipids associate with disease severity in first episode psychosis patients.
A. Checa, A. Malmqvist, L. Flyckt, L. Schwieler +21 more
2018Schizophrenia Research9 citations
Semantic Scholar
[11C]AZ10419096 - a full antagonist PET radioligand for imaging brain 5-HT1B receptors.
Anton Lindberg, S. Nag, M. Schou, A. Takano +6 more
2017Nuclear Medicine and Biology9 citations
Semantic Scholar

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