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G. Civenni · SciRah

Researcher profile · Semantic Scholar

G. Civenni

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G. Civenni — researcher profile on SciRah

h-index: 28
Works: 95
Citations: 4,375

Most-cited papers

The ErbB receptors and their role in cancer progression.
Thomas Holbro, G. Civenni, N. Hynes
2003Experimental Cell Research664 citations
Semantic Scholar
Enhancing chemotherapy efficacy in Pten-deficient prostate tumors by activating the senescence-associated antitumor immunity.
A. Toso, Ajinkya Revandkar, D. Di Mitri, I. Guccini +15 more
2014Cell Reports394 citations Open access
Semantic Scholar
Human CD271-positive melanoma stem cells associated with metastasis establish tumor heterogeneity and long-term growth.
G. Civenni, A. Walter, N. Kobert, D. Mihic-Probst +7 more
2011Cancer Research340 citations Open access
Semantic Scholar
Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism.
Ayyakannu Ayyanan, G. Civenni, L. Ciarloni, C. Morel +7 more
2006Proceedings of the National Academy of Sciences of the United States of America299 citations Open access
Semantic Scholar
Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma
O. Shakhova, D. Zingg, Simon M. Schaefer, L. Hari +12 more
2012Nature Cell Biology268 citations Open access
Semantic Scholar
Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer
Jing-Jing Chen, I. Guccini, D. Di Mitri, Daniela Brina +26 more
2018Nature Genetics196 citations Open access
Semantic Scholar
Glutamate receptor agonists up‐regulate glutamate transporter GLAST in astrocytes
G. Gegelashvili, G. Civenni, G. Racagni, N. C. Danbolt +2 more
1996NeuroReport182 citations
Semantic Scholar
Opposing effects of cancer type-specific SPOP mutations on BET protein degradation and sensitivity to BET inhibitors
H. Janoušková, G. El Tekle, E. Bellini, Namrata D. Udeshi +25 more
2017Nature Medicine171 citations Open access
Semantic Scholar
A Small-Molecule Inhibitor of Lin28.
M. Roos, Ugo Pradère, R. P. Ngondo, A. Behera +12 more
2016ACS Chemical Biology129 citations Open access
Semantic Scholar
ESE3/EHF controls epithelial cell differentiation and its loss leads to prostate tumors with mesenchymal and stem-like features.
D. Albino, Nicole Longoni, Laura Curti, M. Mello-Grand +9 more
2012Cancer Research129 citations Open access
Semantic Scholar
Wnt1 and Wnt5a induce cyclin D1 expression through ErbB1 transactivation in HC11 mammary epithelial cells
G. Civenni, Thomas Holbro, Nancy Hynes
2003118 citations Open access
Semantic Scholar
Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1.
S. Fuchs, D. Herzog, G. Sumara, Stine Büchmann-Møller +8 more
2009Cell Stem Cell112 citations Open access
Semantic Scholar
Epigenetic Control of Mitochondrial Fission Enables Self-Renewal of Stem-like Tumor Cells in Human Prostate Cancer.
G. Civenni, R. Bosotti, A. Timpanaro, Ramiro Vazquez +24 more
2019Cell Metabolism99 citations Open access
Semantic Scholar
Mitochondrial dysfunction induced by a SH2 domain-targeting STAT3 inhibitor leads to metabolic synthetic lethality in cancer cells
D. Genini, Lara Brambilla, E. Laurini, Jessica Merulla +8 more
2017Proceedings of the National Academy of Sciences of the United States of America92 citations Open access
Semantic Scholar
RNAi-mediated silencing of Myc transcription inhibits stem-like cell maintenance and tumorigenicity in prostate cancer.
G. Civenni, A. Malek, D. Albino, R. García-Escudero +6 more
2013Cancer Research89 citations Open access
Semantic Scholar
MicroRNA-424 impairs ubiquitination to activate STAT3 and promote prostate tumor progression.
Cécilia Dallavalle, D. Albino, G. Civenni, Jessica Merulla +12 more
2016Journal of Clinical Investigation86 citations Open access
Semantic Scholar
ETS transcription factor ESE1/ELF3 orchestrates a positive feedback loop that constitutively activates NF-κB and drives prostate cancer progression.
Nicole Longoni, M. Sarti, D. Albino, G. Civenni +12 more
2013Cancer Research85 citations Open access
Semantic Scholar
Impulse flow dependency of galanin release in vivo in the rat ventral hippocampus.
S. Consolo, Gianni Baldi, G. Russi, G. Civenni +2 more
1994Proceedings of the National Academy of Sciences of the United States of America77 citations Open access
Semantic Scholar
Enhanced neuropeptide Y release in the hippocampus is associated with chronic seizure susceptibility in kainic acid treated rats.
A. Vezzani, G. Civenni, M. Rizzi, A. Monno +2 more
1994Brain Research70 citations
Semantic Scholar
Functional effects of D-Phe-c[Cys-Tyr-D-Trp-Lys-Val-Cys]-Trp-NH2 and differential changes in somatostatin receptor messenger RNAs, binding sites and somatostatin release in kainic acid-treated rats.
J. Pérez, A. Vezzani, G. Civenni, P. Tutka +3 more
1995Neuroscience67 citations
Semantic Scholar
Activation of the Lin28/let-7 Axis by Loss of ESE3/EHF Promotes a Tumorigenic and Stem-like Phenotype in Prostate Cancer.
D. Albino, G. Civenni, Cécilia Dallavalle, M. Roos +9 more
2016Cancer Research63 citations Open access
Semantic Scholar
Tumor Cell Plasticity and Angiogenesis in Human Melanomas
D. Mihic-Probst, K. Ikenberg, M. Tinguely, P. Schraml +6 more
2012PLoS ONE58 citations Open access
Semantic Scholar
The ETS factor ESE3/EHF represses IL-6 preventing STAT3 activation and expansion of the prostate cancer stem-like compartment
D. Albino, G. Civenni, S. Rossi, Abhishek Mitra +2 more
2016OncoTarget49 citations Open access
Semantic Scholar
EZH2-induced lysine K362 methylation enhances TMPRSS2-ERG oncogenic activity in prostate cancer
M. Zoma, Laura Curti, D. Shinde, D. Albino +14 more
2021Nature Communications40 citations Open access
Semantic Scholar
A promoter-proximal transcript targeted by genetic polymorphism controls E-cadherin silencing in human cancers
Giuseppina Pisignano, Sara Napoli, M. Magistri, S. Mapelli +14 more
2017Nature Communications39 citations Open access
Semantic Scholar
Circulating extracellular vesicles release oncogenic miR-424 in experimental models and patients with aggressive prostate cancer
D. Albino, M. Falcione, V. Uboldi, D. Temilola +21 more
2021Communications Biology38 citations Open access
Semantic Scholar
EC-70124, a Novel Glycosylated Indolocarbazole Multikinase Inhibitor, Reverts Tumorigenic and Stem Cell Properties in Prostate Cancer by Inhibiting STAT3 and NF-κB
G. Civenni, Nicole Longoni, P. Costales, Cécilia Dallavalle +6 more
2016Molecular Cancer Therapeutics35 citations Open access
Semantic Scholar
Topography-mediated apical guidance in epidermal wound healing
Anastasios Marmaras, Tobias Lendenmann, G. Civenni, D. Franco +3 more
201234 citations
Semantic Scholar
Inhibitory effect of the neuroprotective agent idebenone on arachidonic acid metabolism in astrocytes.
G. Civenni, P. Bezzi, Davide Trotti, A. Volterra +1 more
1999European Journal of Pharmacology26 citations
Semantic Scholar
Short loop-targeting oligoribonucleotides antagonize Lin28 and enable pre-let-7 processing and suppression of cell growth in let-7-deficient cancer cells
M. Roos, Mario A. E. Rebhan, M. Lucic, D. Pavlíček +5 more
2014Nucleic Acids Research24 citations Open access
Semantic Scholar
Engineering melanoma progression in a humanized environment in vivo.
Gregor Kiowski, T. Biedermann, D. Widmer, G. Civenni +4 more
2012Journal of Investigative Dermatology24 citations Open access
Semantic Scholar
Pharmacological inhibition of Lin28 promotes ketogenesis and restores lipid homeostasis in models of non-alcoholic fatty liver disease
Evangelia Lekka, A. Kokanovic, Simone Mosole, G. Civenni +8 more
2022Nature Communications21 citations Open access
Semantic Scholar
Role of astrocytes in glutamate homeostasis. Implications for excitotoxicity.
Arne Schousboe, U. Sonnewald, G. Civenni, Georgi Gegelashvili
1997Advances in Experimental Medicine and Biology21 citations
Semantic Scholar
Transcriptional Reprogramming and Novel Therapeutic Approaches for Targeting Prostate Cancer Stem Cells
G. Civenni, D. Albino, D. Shinde, Ramiro Vazquez +5 more
2019Frontiers in Oncology15 citations Open access
Semantic Scholar
Epigenome-wide impact of MAT2A sustains the androgen-indifferent state and confers synthetic vulnerability in ERG fusion-positive prostate cancer
A. Cacciatore, D. Shinde, C. Musumeci, G. Sandrini +14 more
2024Nature Communications14 citations Open access
Semantic Scholar
Pharmacodynamic and Pharmacokinetic Properties of Full Phosphorothioate Small Interfering RNAs for Gene Silencing In Vivo
Christian Berk, G. Civenni, Yuluan Wang, C. Steuer +2 more
2020Nucleic Acid Therapeutics14 citations Open access
Semantic Scholar
Efficacy of Novel Bromodomain and Extraterminal Inhibitors in Combination with Chemotherapy for Castration-Resistant Prostate Cancer.
Ramiro Vazquez, G. Civenni, A. Kokanovic, D. Shinde +7 more
2019European Urology Oncology14 citations Open access
Semantic Scholar
Gallic acid and methyl-3-O-methyl gallate: a comparative study on their effects on prostate cancer stem cells
G. Civenni, M. Iodice, S. Nabavi, S. Habtemariam +3 more
201514 citations
Semantic Scholar
Proteomics of immune cells from liver tumors reveals immunotherapy targets
F. Canale, J. Neumann, Janusz von Renesse, E. Loggi +26 more
2023Cell Genomics13 citations Open access
Semantic Scholar
Synthesis of Aminoethyl‐Substituted Piperidine Derivatives as σ1 Receptor Ligands with Antiproliferative Properties
Catharina Holtschulte, Frederik Börgel, Stefanie Westphälinger, D. Schepmann +6 more
2022ChemMedChem13 citations Open access
Semantic Scholar
Chemoenzymatic synthesis of 2,6-disubstituted tetrahydropyrans with high σ1 receptor affinity, antitumor and analgesic activity.
Nicole Kopp, G. Civenni, D. Marson, E. Laurini +7 more
2021European journal of medicinal chemistry13 citations Open access
Semantic Scholar
Transcriptional Reprogramming and Inhibition of Tumor-propagating Stem-like Cells by EC-8042 in ERG-positive Prostate Cancer.
D. Shinde, D. Albino, M. Zoma, Azzurra Mutti +9 more
2019European Urology Oncology13 citations
Semantic Scholar
Chemokines in neuroectodermal development and their potential implication in cancer stem cell-driven metastasis.
G. Civenni, L. Sommer
2009Seminars in Cancer Biology13 citations Open access
Semantic Scholar
Wnt1 and Wnt5a induce cyclin D1 expression through ErbB1 transactivation in HC11 mammary epithelial cells (EMBO reports, February 2003) (Correction)
G. Civenni, Thomas Holbro, Nancy Hynes
2003EMBO Reports13 citations Open access
Semantic Scholar
Novel σ1 antagonists designed for tumor therapy: Structure - activity relationships of aminoethyl substituted cyclohexanes.
Nicole Kopp, Catharina Holtschulte, Frederik Börgel, K. Lehmkuhl +8 more
2020European journal of medicinal chemistry11 citations Open access
Semantic Scholar
Abstract 2625: Targeting prostate cancer stem cells (CSCs) with the novel BET bromodomain (BRD) protein inhibitor OTX015
G. Civenni, Silvia Pedrani, S. Allegrini, Antonina Bruccoleri +7 more
20159 citations
Semantic Scholar
Mitochondrial fission and stemness in prostate cancer
G. Civenni, G. Carbone, C. Catapano
2019Aging7 citations Open access
Semantic Scholar
Overview of Genetically Engineered Mouse Models of Prostate Cancer and Their Applications in Drug Discovery
G. Civenni, Giuseppina M. Carbone, C. Catapano
2018Current Protocols in Pharmacology7 citations
Semantic Scholar
Abstract 1379: INCB059872, a novel FAD-directed LSD1 Inhibitor, is active in prostate cancer models and impacts prostate cancer stem-like cells
G. Civenni, Giada Zoppi, Ramiro Vazquez, D. Shinde +6 more
2018Molecular and Cellular Biology / Genetics7 citations
Semantic Scholar
Targeting Promoter-Associated Noncoding RNA In Vivo.
G. Civenni
2017Methods in molecular biology7 citations
Semantic Scholar

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