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Daniela Brina · SciRah

Researcher profile · Semantic Scholar

Daniela Brina

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Daniela Brina — researcher profile on SciRah

h-index: 20
Works: 28
Citations: 1,569

Most-cited papers

Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer
Jing-Jing Chen, I. Guccini, D. Di Mitri, Daniela Brina +26 more
2018Nature Genetics196 citations Open access
Semantic Scholar
Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis.
I. Guccini, Ajinkya Revandkar, M. d'Ambrosio, M. Colucci +22 more
2020Cancer Cell169 citations Open access
Semantic Scholar
Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer.
Nicolò Bancaro, B. Calì, M. Troiani, A. R. Elia +27 more
2023Cancer Cell168 citations Open access
Semantic Scholar
Senescence in cancer.
Manuel Colucci, M. Sarill, Martino Maddalena, Aurora Valdata +12 more
2025Cancer Cell119 citations Open access
Semantic Scholar
Impairment of cytoplasmic eIF6 activity restricts lymphomagenesis and tumor progression without affecting normal growth.
A. Miluzio, Anne Beugnet, Stefano Grosso, Daniela Brina +5 more
2011Cancer Cell102 citations Open access
Semantic Scholar
Targeting senescence induced by age or chemotherapy with a polyphenol-rich natural extract improves longevity and healthspan in mice
S. Zumerle, M. Sarill, M. Saponaro, Manuel Colucci +39 more
2024Nature Aging101 citations Open access
Semantic Scholar
eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription
Daniela Brina, A. Miluzio, Sara Ricciardi, K. Clarke +15 more
2015Nature Communications95 citations Open access
Semantic Scholar
RACK1 depletion in a mouse model causes lethality, pigmentation deficits and reduction in protein synthesis efficiency
Viviana Volta, Anne Beugnet, S. Gallo, L. Magri +5 more
2012Cellular and Molecular Life Sciences78 citations
Semantic Scholar
eIF6 anti-association activity is required for ribosome biogenesis, translational control and tumor progression.
Daniela Brina, A. Miluzio, Sara Ricciardi, S. Biffo
2015Biochimica et Biophysica Acta72 citations
Semantic Scholar
The Akt/mTOR and MNK/eIF4E pathways rewire the prostate cancer translatome to secrete HGF, SPP1 and BGN and recruit suppressive myeloid cells
Daniela Brina, Adele Ponzoni, M. Troiani, B. Calì +35 more
2023Nature Cancer69 citations Open access
Semantic Scholar
HER3 is an Actionable Target in Advanced Prostate Cancer.
V. Gil, S. Miranda, R. Riisnaes, B. Gurel +41 more
2021Cancer Research55 citations Open access
Semantic Scholar
Translational control by 80S formation and 60S availability: The central role of eIF6, a rate limiting factor in cell cycle progression and tumorigenesis
Daniela Brina, Stefano Grosso, A. Miluzio, S. Biffo
2011Cell Cycle46 citations Open access
Semantic Scholar
30 Days of Continuous Olanzapine Infusion Determines Energy Imbalance, Glucose Intolerance, Insulin Resistance, and Dyslipidemia in Mice
R. Coccurello, Daniela Brina, A. Caprioli, R. Conti +3 more
2009Journal of Clinical Psychopharmacology44 citations Open access
Semantic Scholar
Expression and activity of eIF6 trigger Malignant Pleural Mesothelioma growth in vivo
A. Miluzio, S. Oliveto, E. Pesce, L. Mutti +5 more
2015OncoTarget41 citations Open access
Semantic Scholar
Targeting of eIF6-driven translation induces a metabolic rewiring that reduces NAFLD and the consequent evolution to hepatocellular carcinoma
A. Scagliola, A. Miluzio, Gabriele Ventura, S. Oliveto +11 more
2021Nature Communications33 citations Open access
Semantic Scholar
The Role of Eif6 in Skeletal Muscle Homeostasis Revealed by Endurance Training Co-expression Networks
K. Clarke, Sara Ricciardi, Timothy Pearson, I. Bharudin +21 more
2017Cell Reports30 citations Open access
Semantic Scholar
Translational control by mTOR-independent routes: how eIF6 organizes metabolism.
A. Miluzio, Sara Ricciardi, Nicola Manfrini, R. Alfieri +3 more
2016Biochemical Society Transactions27 citations
Semantic Scholar
Sensitivity of Global Translation to mTOR Inhibition in REN Cells Depends on the Equilibrium between eIF4E and 4E-BP1
Stefano Grosso, E. Pesce, Daniela Brina, Anne Beugnet +2 more
2011PLoS ONE24 citations Open access
Semantic Scholar
High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4+ T cells in both mice and humans.
Nicola Manfrini, Sara Ricciardi, A. Miluzio, M. Fedeli +9 more
2017Developmental and Comparative Immunology23 citations
Semantic Scholar
JHDM1B expression regulates ribosome biogenesis and cancer cell growth in a p53 dependent manner
M. Penzo, L. Casoli, Daniela Pollutri, L. Sicuro +7 more
2015International Journal of Cancer20 citations
Semantic Scholar
Eukaryotic translation initiation factor 6 is a novel regulator of reactive oxygen species‐dependent megakaryocyte maturation
Sara Ricciardi, A. Miluzio, Daniela Brina, K. Clarke +5 more
2015Journal of Thrombosis and Haemostasis18 citations Open access
Semantic Scholar
Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer.
B. Calí, M. Troiani, S. Bressan, Giuseppe Attanasio +41 more
2024Cancer Cell17 citations Open access
Semantic Scholar
JNK inhibition arrests cotranslational degradation.
V. Gandin, Daniela Brina, P. Marchisio, S. Biffo
2010Biochimica et Biophysica Acta13 citations Open access
Semantic Scholar
Tumor-associated neutrophil precursors impair homologous DNA repair and promote sensitivity to PARP inhibition
S. Mukherjee, Cindy Garda, Letizia Boffa, A. R. Elia +31 more
2025Nature Communications4 citations Open access
Semantic Scholar
Publisher Correction: Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer
Jing-Jing Chen, I. Guccini, D. Di Mitri, Daniela Brina +26 more
2018Nature Genetics4 citations Open access
Semantic Scholar
1682PCompartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer
Jing-Jing Chen, I. Guccini, D. Di Mitri, Daniela Brina +1 more
20172 citations Open access
Semantic Scholar
eIF6 links histone acetylation with translational control of HDAC in skeletal muscle
A. Scagliola, A. Miluzio, I. Ferrari, Daniela Brina +2 more
2026Molecular and Cellular Biochemistry0 citations Open access
Semantic Scholar
Abstract 2807: HER3 is an actionable target in advanced prostate cancer
S. Miranda, V. Gil, R. Riisnaes, B. Gurel +40 more
2022Cancer Research0 citations
Semantic Scholar

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