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Frederik Börgel · SciRah

Researcher profile · Semantic Scholar

Frederik Börgel

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Frederik Börgel — researcher profile on SciRah

h-index: 11
Works: 18
Citations: 320

Most-cited papers

Structure-Activity Relationship of Purine and Pyrimidine Nucleotides as Ecto-5′-Nucleotidase (CD73) Inhibitors
Anna Junker, Christian Renn, Clemens Dobelmann, Vigneshwaran Namasivayam +11 more
2019Journal of Medicinal Chemistry58 citations Open access
Semantic Scholar
Design, (Radio)Synthesis, and in Vitro and in Vivo Evaluation of Highly Selective and Potent Matrix Metalloproteinase 12 (MMP-12) Inhibitors as Radiotracers for Positron Emission Tomography.
Viktoria Butsch, Frederik Börgel, F. Galla, Katrin Schwegmann +5 more
2018Journal of Medicinal Chemistry43 citations
Semantic Scholar
Pharmacokinetic properties of enantiomerically pure GluN2B selective NMDA receptor antagonists with 3-benzazepine scaffold.
Frederik Börgel, F. Galla, K. Lehmkuhl, D. Schepmann +2 more
2019Journal of Pharmaceutical and Biomedical Analysis26 citations
Semantic Scholar
Synthesis and Pharmacological Evaluation of Enantiomerically Pure GluN2B Selective NMDA Receptor Antagonists
Frederik Börgel, Marina Szermerski, J. Schreiber, Louisa Temme +7 more
2018ChemMedChem23 citations
Semantic Scholar
The Action of Reproductive Fluids and Contained Steroids, Prostaglandins, and Zn2+ on CatSper Ca2+ Channels in Human Sperm
J. K. Jeschke, C. Biagioni, Tobias Schierling, I. V. Wagner +10 more
2021Frontiers in Cell and Developmental Biology22 citations Open access
Semantic Scholar
Synthesis and evaluation of a [18F]BODIPY-labeled caspase-inhibitor.
Christian Paul Ortmeyer, G. Haufe, Katrin Schwegmann, S. Hermann +5 more
2017Bioorganic & Medicinal Chemistry22 citations
Semantic Scholar
Rigidity versus Flexibility: Is This an Issue in σ1 Receptor Ligand Affinity and Activity?
Frauke Weber, S. Brune, Frederik Börgel, Carsten Lange +7 more
2016Journal of Medicinal Chemistry22 citations Open access
Semantic Scholar
Synthesis of Aminoethyl‐Substituted Piperidine Derivatives as σ1 Receptor Ligands with Antiproliferative Properties
Catharina Holtschulte, Frederik Börgel, Stefanie Westphälinger, D. Schepmann +6 more
2022ChemMedChem13 citations Open access
Semantic Scholar
Synthesis, Receptor Affinity, and Antiallodynic Activity of Spirocyclic σ Receptor Ligands with Exocyclic Amino Moiety.
Melanie Bergkemper, Elisabeth Kronenberg, S. Thum, Frederik Börgel +7 more
2018Journal of Medicinal Chemistry13 citations Open access
Semantic Scholar
Optimization of pharmacokinetic properties by modification of a carbazole-based cannabinoid receptor subtype 2 (CB2) ligand.
Dominik Heimann, Frederik Börgel, H. D. de Vries, K. Bachmann +5 more
2018European journal of medicinal chemistry13 citations Open access
Semantic Scholar
Fluorinated GluN2B Receptor Antagonists with a 3‐Benzazepine Scaffold Designed for PET Studies
Marina Szermerski, Frederik Börgel, D. Schepmann, Ahmed Haider +3 more
2018ChemMedChem12 citations
Semantic Scholar
Synthesis and Biological Evaluation of Natural-Product-Inspired, Aminoalkyl-Substituted 1-Benzopyrans as Novel Antiplasmodial Agents.
Jan-Frederik Uth, Frederik Börgel, K. Lehmkuhl, D. Schepmann +6 more
2021Journal of Medicinal Chemistry11 citations
Semantic Scholar
Novel σ1 antagonists designed for tumor therapy: Structure - activity relationships of aminoethyl substituted cyclohexanes.
Nicole Kopp, Catharina Holtschulte, Frederik Börgel, K. Lehmkuhl +8 more
2020European journal of medicinal chemistry11 citations Open access
Semantic Scholar
Phenylethylene glycol-derived LpxC inhibitors with diverse Zn2+-binding groups
Magdalena Galster, Marius Löppenberg, F. Galla, Frederik Börgel +3 more
2019Tetrahedron10 citations Open access
Semantic Scholar
Optimization of the metabolic stability of a fluorinated cannabinoid receptor subtype 2 (CB2) ligand designed for PET studies.
Dominik Heimann, Frederik Börgel, H. D. de Vries, Marius Patberg +5 more
2018European journal of medicinal chemistry8 citations Open access
Semantic Scholar
Synthesis and Pharmacological Evaluation of Fluorinated Quinoxaline‐Based κ‐Opioid Receptor (KOR) Agonists Designed for PET Studies
Giovanni Tangherlini, Frederik Börgel, D. Schepmann, Samuel T. Slocum +7 more
2020ChemMedChem7 citations Open access
Semantic Scholar
Impact of hydroxy moieties at the benzo[7]annulene ring system of GluN2B ligands: Design, synthesis and biological evaluation.
Louisa Temme, Frederik Börgel, D. Schepmann, D. Robaa +3 more
2019Bioorganic & Medicinal Chemistry6 citations Open access
Semantic Scholar
Synthesis and biological evaluation of PET tracers designed for imaging of calcium activated potassium channel 3.1 (KCa3.1) channels in vivo
Kathrin Brömmel, C. Konken, Frederik Börgel, Henry Obeng-Darko +6 more
2021RSC Advances0 citations Open access
Semantic Scholar

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B. Wünsch×16
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B. Wünsch — researcher profile on SciRah
D. Schepmann×13
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K. Lehmkuhl×4
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F. Galla×3
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Katrin Schwegmann

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