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H. Patel · SciRah

Researcher profile · Semantic Scholar

H. Patel

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H. Patel — researcher profile on SciRah

h-index: 10
Works: 31
Citations: 793

Most-cited papers

Selective estrogen receptor modulators (SERMs) and selective estrogen receptor degraders (SERDs) in cancer treatment.
H. Patel, Teeru Bihani
2017Pharmacology and Therapeutics414 citations Open access
Semantic Scholar
Elacestrant (RAD1901), a Selective Estrogen Receptor Degrader (SERD), Has Antitumor Activity in Multiple ER+ Breast Cancer Patient-derived Xenograft Models
Teeru Bihani, H. Patel, H. Arlt, N. Tao +5 more
2017Clinical Cancer Research129 citations Open access
Semantic Scholar
Elacestrant (RAD1901) exhibits anti-tumor activity in multiple ER+ breast cancer models resistant to CDK4/6 inhibitors
H. Patel, N. Tao, Kyung-min Lee, M. Huerta +5 more
2019Breast Cancer Research67 citations Open access
Semantic Scholar
Selective human Estrogen Receptor Partial Agonists (ShERPAs) for Tamoxifen-Resistant Breast Cancer
R. Xiong, H. Patel, Lauren M. Gutgesell, Jiong Zhao +9 more
2015Journal of Medicinal Chemistry55 citations Open access
Semantic Scholar
Selective Androgen Receptor Modulator RAD140 Inhibits the Growth of Androgen/Estrogen Receptor–Positive Breast Cancer Models with a Distinct Mechanism of Action
Zi-Yang Yu, Su-Qin He, Dannie Wang, H. Patel +4 more
2017Clinical Cancer Research32 citations Open access
Semantic Scholar
A Chimeric SERM-Histone Deacetylase Inhibitor Approach to Breast Cancer Therapy
H. Patel, Marton I. Siklos, Hazem Abdelkarim, Emma Mendonca +3 more
2013ChemMedChem24 citations Open access
Semantic Scholar
Elacestrant demonstrates strong anti-estrogenic activity in PDX models of estrogen-receptor positive endocrine-resistant and fulvestrant-resistant breast cancer
S. Pancholi, Nikiana Simigdala, Ricardo Ribas, Eugene F Schuster +8 more
2022npj Breast Cancer20 citations Open access
Semantic Scholar
Novel Selective Estrogen Mimics for the Treatment of Tamoxifen-Resistant Breast Cancer
M. E. Molloy, B. Perez White, Teshome B. Gherezghiher, Bradley T. Michalsen +7 more
2014Molecular Cancer Therapeutics18 citations Open access
Semantic Scholar
Abstract P6-20-08: Anti-tumor activity of elacestrant (RAD1901) in models harboring ESR1 mutations resistant to standard of care therapies
H. Patel, N. Tao, H. Arlt, Teeru Bihani
2019Poster Session Abstracts11 citations
Semantic Scholar
SERMs attenuate estrogen-induced malignant transformation of human mammary epithelial cells by upregulating detoxification of oxidative metabolites
L. P. Madhubhani, P. Hemachandra, H. Patel, R. Esala +12 more
2014Cancer Prevention Research10 citations Open access
Semantic Scholar
Modeling the novel SERD elacestrant in cultured fulvestrant-refractory HR-positive breast circulating tumor cells
Taronish D. Dubash, A. Bardia, Brian Chirn, B. Reeves +19 more
2023Breast Cancer Research and Treatment5 citations Open access
Semantic Scholar
Abstract 6264: NUV-868, a novel BD2-selective BET inhibitor, in combination with enzalutamide or olaparib, inhibits growth of solid tumor xenografts
H. Patel, Jennifer R Hertzog, Laura Heller, Spandana R Vootukuri +3 more
2023Cancer Research4 citations
Semantic Scholar
Abstract P4-13-03: Elacestrant (RAD1901) demonstrates anti-tumor activity in models resistant to CDK4/6 inhibitors
H. Patel, N. Tao, H. Arlt, Teeru Bihani
2019Poster Session Abstracts3 citations
Semantic Scholar
Abstract P4-01-06: Elacestrant (RAD1901) inhibits growth of ex vivo cultured circulating tumor cells derived from hormone receptor-positive metastatic breast cancer (mBC) patients including those harboring ESR1 mutations
Taronish D. Dubash, A. Bardia, B. Reeves, Brian Chirn +9 more
2020Poster Session Abstracts1 citations
Semantic Scholar
Abstract P3-04-22: RAD1901 demonstrates anti-tumor activity in multiple models of ER-positive breast cancer treatment resistance
Teeru Bihani, H. Arlt, H. Brechbuhl, H. Patel +5 more
20171 citations
Semantic Scholar
Abstract 5864: Taletrectinib, a next generation selective ROS1 inhibitor, demonstrates a differentiated profile in ROS1 fusion models
H. Patel, Laura Heller, Kevin Bowman, Zheyi Hu +3 more
2026Cancer Research0 citations
Semantic Scholar
Challenging paradigms: utilizing pancreatic cancer organoids to advance personalized medicine
J. D. Price, F. S. Vizeacoumar, O. Abuhussein, V. Maranda +46 more
2025HPB0 citations Open access
Semantic Scholar
P3.12.04 Taletrectinib, a Next Generation Selective ROS1 Inhibitor, Exhibits a Differentiated Profile in ROS1 Fusion Models
H. Patel, L. Heller, K. Bowman, Z. Hu +4 more
2025Journal of Thoracic Oncology0 citations Open access
Semantic Scholar
Abstract 5612: Taletrectinib, a next generation selective ROS1 inhibitor, inhibits growth of ROS1 wild-type and ROS1-G2032R xenografts
H. Patel, Laura Heller, K. Bowman, Zheyi Hu +4 more
2025Cancer Research0 citations
Semantic Scholar
Abstract CT073: Efficacy of novel oral SERD elacestrant in fulvestrant-refractory hormone receptor-positive (HR+) breast cancer: a translational investigation
Taronish D. Dubash, A. Bardia, Brian Chirn, B. Reeves +18 more
2023Cancer Research0 citations
Semantic Scholar
Abstract P5-01-05: Genomic alterations detected by circulating tumor DNA and correlation with response to treatment with elacestrant, an oral selective estrogen receptor degrader, in phase 1 trials in postmenopausal women with ER+/HER2- advanced/metastatic breast cancer
Teeru Bihani, JungAh Jung, H. Patel, A. Bardia +14 more
2020Poster Session Abstracts0 citations
Semantic Scholar
Novel Approaches to Endocrine Therapy in Endocrine-Independent Breast Cancer
H. Patel
20160 citations
Semantic Scholar
Abstract 3485: Estrogen receptor ligands and their responses in de novo and tamoxifen resistant cell models
Lauren M. Gutgesell, G. Thatcher, H. Patel, R. Xiong
20160 citations
Semantic Scholar
Abstract P3-05-23: Novel, non-uterotrophic, selective estrogen mimics cause regression of tamoxifen-resistant breast cancer in 2D and 3D cultures and in mouse xenograft models
R. ThatcherGregory, R. Xiong, H. Patel, Jiong Zhao +4 more
20150 citations
Semantic Scholar
Abstract C98: Selective estrogen mimics (SEMs) for the treatment of tamoxifen resistant breast cancer
H. Patel, R. Xiong, Lauren M. Gutgesell, Jiong Zhao +3 more
20150 citations
Semantic Scholar
Abstract 2710: Lead based development and evaluation of selective estrogen mimics in tamoxifen resistant breast cancer
H. Patel, R. Xiong, Jiong Zhao, M. E. Molloy +2 more
20140 citations
Semantic Scholar
Abstract 619: Selective estrogen mimics for the treatment of tamoxifen-resistant breast cancer
M. E. Molloy, B. Perez White, Hui-Ping Zhao, Bradley T. Michalsen +6 more
20140 citations
Semantic Scholar
Small Molecule Therapeutics Novel Selective Estrogen Mimics for the Treatment of Tamoxifen-Resistant Breast Cancer
M. E. Molloy, B. Perez White, Teshome B. Gherezghiher, Bradley T. Michalsen +7 more
20140 citations
Semantic Scholar
316 Potent, partial agonists at ERalpha as selective estrogen mimics for treatment of tamoxifen-resistant breast cancer
G. Thatcher, R. Xiong, H. Patel, J. Zhao +4 more
20140 citations
Semantic Scholar
Cover Picture: A Chimeric SERM–Histone Deacetylase Inhibitor Approach to Breast Cancer Therapy (ChemMedChem 3/2014)
H. Patel, Marton I. Siklos, Hazem Abdelkarim, Emma Mendonca +3 more
20140 citations
Semantic Scholar
Utilizing equity leadership teams to create culturally responsive classrooms
H. Patel
0 citations
Semantic Scholar

Frequent co-authors

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Teeru Bihani×11
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Teeru Bihani — researcher profile on SciRah
R. Xiong×10
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R. Xiong — researcher profile on SciRah
G. Thatcher×10
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G. Thatcher — researcher profile on SciRah
D. Tonetti×8
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D. Tonetti — researcher profile on SciRah

×7

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H. Arlt — researcher profile on SciRah

M. E. Molloy×7

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M. E. Molloy — researcher profile on SciRah

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N. Tao — researcher profile on SciRah

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Jiong Zhao — researcher profile on SciRah

G. Hattersley×4

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G. Hattersley — researcher profile on SciRah

Hui-Ping Zhao×4

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Hui-Ping Zhao — researcher profile on SciRah

Marton I. Siklos×4

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Marton I. Siklos — researcher profile on SciRah

Bradley T. Michalsen×4

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Bradley T. Michalsen — researcher profile on SciRah