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Mazhar Adli · SciRah

Researcher profile · Semantic Scholar

Mazhar Adli

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Mazhar Adli — researcher profile on SciRah

h-index: 36
Works: 74
Citations: 11K

Most-cited papers

Initial genome sequencing and analysis of multiple myeloma
M. Chapman, Michael S. Lawrence, J. Keats, K. Cibulskis +46 more
2011Nature1,478 citations Open access
Semantic Scholar
The CRISPR tool kit for genome editing and beyond
Mazhar Adli
2018Nature Communications1,402 citations Open access
Semantic Scholar
Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains
M. Ku, Richard P. Koche, E. Rheinbay, E. Mendenhall +13 more
2008PLoS Genetics1,057 citations Open access
Semantic Scholar
Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease
Cem Kuscu, Şevki Arslan, Ritambhara Singh, Jeremy Thorpe +1 more
2014Nature Biotechnology769 citations
Semantic Scholar
ASXL1 Mutations Promote Myeloid Transformation Through Loss of PRC2-Mediated Gene Repression
O. Abdel-Wahab, Mazhar Adli, Lindsay M. LaFave, Jie Gao +17 more
2012Cancer Cell601 citations Open access
Semantic Scholar
Genome-wide chromatin state transitions associated with developmental and environmental cues
Jiang Zhu, Mazhar Adli, J. Zou, Griet Verstappen +16 more
2013Cell548 citations Open access
Semantic Scholar
Using whole exome sequencing to identify inherited causes of autism
Timothy W. Yu, Maria H. Chahrour, Michael E. Coulter, S. Jiralerspong +45 more
2013Neuron452 citations Open access
Semantic Scholar
Heterodimeric JAK-STAT Activation as a Mechanism of Persistence to JAK2 Inhibitor Therapy
Priya Koppikar, Neha Bhagwat, O. Kilpivaara, T. Manshouri +18 more
2011Nature366 citations Open access
Semantic Scholar
Reprogramming factor expression induces rapid and widespread targeted chromatin remodeling
Richard P. Koche, Zachary D. Smith, Mazhar Adli, H. Gu +4 more
2011Cell Stem Cell365 citations Open access
Semantic Scholar
CRISPR-STOP: gene silencing through base-editing-induced nonsense mutations
Cem Kuscu, Mahmut Parlak, Turan Tufan, Jiekun Yang +4 more
2017Nature Methods332 citations
Semantic Scholar
Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo
O. Abdel-Wahab, Jie Gao, Mazhar Adli, A. Dey +23 more
2013Journal of Experimental Medicine328 citations Open access
Semantic Scholar
Live cell imaging of low- and non-repetitive chromosome loci using CRISPR-Cas9
Peiwu Qin, Mahmut Parlak, Cem Kuscu, J. Bandaria +6 more
2017Nature Communications227 citations Open access
Semantic Scholar
Cas9-chromatin binding information enables more accurate CRISPR off-target prediction
Ritambhara Singh, Cem Kuscu, A. Quinlan, Yan-Jun Qi +1 more
2015Nucleic Acids Research215 citations Open access
Semantic Scholar
CRISPR ethics: moral considerations for applications of a powerful tool
Carolyn Brokowski, Mazhar Adli
2018Journal of Molecular Biology205 citations Open access
Semantic Scholar
Whole-genome chromatin profiling from limited numbers of cells using nano-ChIP-seq
Mazhar Adli, B. Bernstein
2011Nature Protocols185 citations Open access
Semantic Scholar
Genomewide Chromatin Maps Derived from Limited Numbers of Hematopoietic Progenitors
Mazhar Adli, Jiang Zhu, B. Bernstein
2010Nature Methods176 citations Open access
Semantic Scholar
Adenomyosis pathogenesis: insights from next-generation sequencing
S. Bulun, Ş. Yıldız, Mazhar Adli, Jian-Jun Wei
2021Human Reproduction Update162 citations Open access
Semantic Scholar
Endometriosis and adenomyosis: shared pathophysiology.
S. Bulun, Ş. Yıldız, Mazhar Adli, D. Chakravarti +7 more
2023Fertility and Sterility149 citations Open access
Semantic Scholar
Evolution of Osteocrin as an activity-regulated factor in the primate brain
Bulent Ataman, G. Boulting, D. Harmin, Marty G. Yang +20 more
2016Nature139 citations Open access
Semantic Scholar
Chromatin Profiling by Directly Sequencing Small Quantities of Immunoprecipitated DNA
Alon Goren, Fatih Ozsolak, N. Shoresh, M. Ku +7 more
2009Nature Methods122 citations Open access
Semantic Scholar
Degree of Recruitment of DOT1L to MLL-AF9 Defines Level of H3K79 Di- and Tri-methylation on Target Genes and Transformation Potential
Aravinda Kuntimaddi, N. Achille, Jeremy Thorpe, Alyson A. Lokken +5 more
2015Cell Reports119 citations Open access
Semantic Scholar
IKKα and IKKβ Each Function to Regulate NF-κB Activation in the TNF-Induced/Canonical Pathway
Mazhar Adli, Evan C. Merkhofer, P. Cogswell, A. Baldwin
2010PLoS ONE113 citations Open access
Semantic Scholar
IKK-i/IKKϵ Controls Constitutive, Cancer Cell-associated NF-κB Activity via Regulation of Ser-536 p65/RelA Phosphorylation*
Mazhar Adli, A. Baldwin
2006Journal of Biological Chemistry112 citations Open access
Semantic Scholar
Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers
A. Illendula, J. Gilmour, J. Grembecka, Venkata Sesha Srimath Tirumala +19 more
2016EBioMedicine95 citations Open access
Semantic Scholar
Ethanolamine Signaling Promotes Salmonella Niche Recognition and Adaptation during Infection
C. Anderson, D. E. Clark, Mazhar Adli, M. M. Kendall
2015PLoS Pathogens93 citations Open access
Semantic Scholar
Minireview: transgenerational epigenetic inheritance: focus on endocrine disrupting compounds.
E. Rissman, Mazhar Adli
2014Endocrinology93 citations Open access
Semantic Scholar
Transgenerational Effects of Bisphenol A on Gene Expression and DNA Methylation of Imprinted Genes in Brain
Z. Drobnâ, A. Henriksen, J. Wolstenholme, Catalina Montiel +7 more
2018Endocrinology89 citations Open access
Semantic Scholar
Correction: Discovery of CTCF-Sensitive Cis-Spliced Fusion RNAs between Adjacent Genes in Human Prostate Cells
Fujun Qin, Zhen-Guo Song, Mihaela Babiceanu, Yan-Su Song +4 more
2015PLoS Genetics88 citations Open access
Semantic Scholar
Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells
Xiaolong Wei, Jiekun Yang, Sara J. Adair, Harun Ozturk +11 more
2020Proceedings of the National Academy of Sciences of the United States of America82 citations Open access
Semantic Scholar
CRISPR knockout screening identifies combinatorial drug targets in pancreatic cancer and models cellular drug response
K. Szlachta, Cem Kuscu, Turan Tufan, Sara J. Adair +12 more
2018Nature Communications71 citations Open access
Semantic Scholar
Regulation of Mammalian Target of Rapamycin Activity in PTEN-Inactive Prostate Cancer Cells by IκB Kinase α
Han C. Dan, Mazhar Adli, A. Baldwin
200761 citations Open access
Semantic Scholar
Chemotherapy-induced distal enhancers drive transcriptional programs to maintain the chemoresistant state in ovarian cancer.
Stephen Shang, Jiekun Yang, A. Jazaeri, A. Duval +12 more
2019Cancer Research50 citations Open access
Semantic Scholar
Super-enhancers maintain renin-expressing cell identity and memory to preserve multi-system homeostasis
M. F. Martinez, S. Medrano, Evan A. Brown, Turan Tufan +7 more
2018Journal of Clinical Investigation44 citations Open access
Semantic Scholar
Regulation of mammalian target of rapamycin activity in PTEN-inactive prostate cancer cells by I kappa B kinase alpha.
Han C. Dan, Mazhar Adli, A. Baldwin
2007Cancer Research44 citations
Semantic Scholar
Resveratrol protects against 4‐HNE induced oxidative stress and apoptosis in Swiss 3T3 fibroblasts
O. Kutuk, Mazhar Adli, G. Poli, H. Basaga
2004Biofactors44 citations
Semantic Scholar
Adenomyosis: single-cell transcriptomic analysis reveals a paracrine mesenchymal–epithelial interaction involving the WNT/ SFRP pathway
Ş. Yıldız, Meric Kinali, Jian-Jun Wei, M. Milad +3 more
2023Fertility and Sterility40 citations Open access
Semantic Scholar
Temporal and Spatial Epigenome Editing Allows Precise Gene Regulation in Mammalian Cells.
Cem Kuscu, Rashad Mammadov, A. Czikora, Hayrunnisa Unlu +6 more
2019Journal of Molecular Biology35 citations Open access
Semantic Scholar
FOXK2 promotes ovarian cancer stemness by regulating the unfolded protein response pathway
Yaqi Zhang, Yi-Nu Wang, Guangyuan Zhao, E. Tanner +2 more
2022Journal of Clinical Investigation32 citations Open access
Semantic Scholar
Evolutionary Biology and Gene Editing of Cat Allergen, Fel d 1
Nicole F Brackett, B. Davis, Mazhar Adli, A. Pomés +1 more
2022The CRISPR Journal25 citations Open access
Semantic Scholar
Recurrent mutations at estrogen receptor binding sites alter chromatin topology and distal gene expression in breast cancer
Jiekun Yang, Xiaolong Wei, Turan Tufan, Cem Kuscu +5 more
2018Genome Biology24 citations Open access
Semantic Scholar
Engineered MED12 mutations drive leiomyoma-like transcriptional and metabolic programs by altering the 3D genome compartmentalization
Kadir Buyukcelebi, Xintong Chen, Fatih Abdula, Hoda Elkafas +10 more
2023Nature Communications22 citations Open access
Semantic Scholar
CRISPR-Cas9-AID base editor is a powerful gain-of-function screening tool
Cem Kuscu, Mazhar Adli
2016Nature Methods22 citations
Semantic Scholar
CRISPR-STOP: Gene silencing through base editing-induced nonsense mutations
Cem Kuscu, Turan Tufan, Jiekun Yang, Mazhar Adli
201720 citations Open access
Semantic Scholar
ISL2 is a putative tumor suppressor whose epigenetic silencing reprograms the metabolism of pancreatic cancer.
Harun Ozturk, Harun Cingoz, Turan Tufan, Jiekun Yang +18 more
2022Developmental Cell18 citations Open access
Semantic Scholar
Epigenetic States of Nephron Progenitors and Epithelial Differentiation
Mazhar Adli, Mahmut Parlak, Yuwen Li, S. El-Dahr
2015Journal of Cellular Biochemistry16 citations Open access
Semantic Scholar
Mapping and making sense of non-coding mutations in the genome.
Jiekun Yang, Mazhar Adli
2019Cancer Research13 citations
Semantic Scholar
ASXL1 Mutations Promote Myeloid Transformation Through Inhibition of PRC2-Mediated Gene Repression
O. Abdel-Wahab, Mazhar Adli, Lindsay M. Saunders, Jie Gao +11 more
201113 citations
Semantic Scholar
Discovery of CTCF-Sensitive Cis-Spliced Fusion RNAs between Adjacent Genes in Human Prostate Cells
Fu-Jun Qin, Zhenguo Song, Mihaela Babiceanu, Yan Song +4 more
2015PLoS Genetics12 citations Open access
Semantic Scholar
A Functional Variant on 9p21.3 Related to Glioma Risk Affects Enhancer Activity and Modulates Expression of CDKN2B‐AS1
M. Ali, C. P. K. Patro, M. Devall, C. Dampier +5 more
2021Human Mutation11 citations Open access
Semantic Scholar
The Mouseion at the JAXlibrary The Mouseion at the JAXlibrary
Mourad Wagdy, C. Pawan, K. Patro, J. J. Zhu +7 more
11 citations
Semantic Scholar

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Cem Kuscu×15
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B. Bernstein×11
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Turan Tufan×8
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Jiekun Yang×8
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Ritambhara Singh

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