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S. Pellett · SciRah

Researcher profile · Semantic Scholar

S. Pellett

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S. Pellett — researcher profile on SciRah

h-index: 23
Works: 94
Citations: 2,003

Most-cited papers

A Novel Botulinum Neurotoxin, Previously Reported as Serotype H, Has a Hybrid-Like Structure With Regions of Similarity to the Structures of Serotypes A and F and Is Neutralized With Serotype A Antitoxin.
S. Maslanka, C. Lúquez, J. Dykes, W. Tepp +7 more
2016Journal of Infectious Diseases143 citations Open access
Semantic Scholar
Characterization of Botulinum Neurotoxin A Subtypes 1 Through 5 by Investigation of Activities in Mice, in Neuronal Cell Cultures, and In Vitro
Regina C. M. Whitemarsh, W. Tepp, M. Bradshaw, Guangyun Lin +4 more
2013Infection and Immunity113 citations Open access
Semantic Scholar
A neuronal cell‐based botulinum neurotoxin assay for highly sensitive and specific detection of neutralizing serum antibodies
S. Pellett, William H. Tepp, Colin M. Clancy, G. Borodic +1 more
2007FEBS Letters90 citations Open access
Semantic Scholar
Bimodal modulation of the botulinum neurotoxin protein-conducting channel
Audrey Fischer, Y. Nakai, L. M. Eubanks, Colin M. Clancy +6 more
2009Proceedings of the National Academy of Sciences of the United States of America86 citations Open access
Semantic Scholar
In vivo onset and duration of action varies for Botulinum neurotoxin A subtypes 1–5
S. Pellett, W. Tepp, Regina C. M. Whitemarsh, M. Bradshaw +1 more
2015Toxicon85 citations Open access
Semantic Scholar
Botulinum neurotoxin subtype A2 enters neuronal cells faster than subtype A1
Christina L. Pier, Chen Chen, W. Tepp, Guangyun Lin +4 more
2010FEBS Letters81 citations Open access
Semantic Scholar
Current Status and Future Directions of Botulinum Neurotoxins for Targeting Pain Processing
S. Pellett, T. Yaksh, Roshni Ramachandran
2015Toxins78 citations Open access
Semantic Scholar
Persistence of Botulinum Neurotoxin A Subtypes 1-5 in Primary Rat Spinal Cord Cells
Regina C. M. Whitemarsh, W. Tepp, E. Johnson, S. Pellett
2014PLoS ONE78 citations Open access
Semantic Scholar
Progress in Cell Based Assays for Botulinum Neurotoxin Detection
S. Pellett
2013Current Topics in Microbiology and Immunology77 citations Open access
Semantic Scholar
Novel application of human neurons derived from induced pluripotent stem cells for highly sensitive botulinum neurotoxin detection.
Regina C. M. Whitemarsh, Monica J. Strathman, Lucas G. Chase, Casey Stankewicz +3 more
2012Toxicological Sciences77 citations Open access
Semantic Scholar
The Light Chain Defines the Duration of Action of Botulinum Toxin Serotype A Subtypes
S. Pellett, M. Bradshaw, W. Tepp, Christina L. Pier +4 more
2018mBio63 citations Open access
Semantic Scholar
Comparison of the primary rat spinal cord cell (RSC) assay and the mouse bioassay for botulinum neurotoxin type A potency determination.
S. Pellett, W. Tepp, S. Toth, E. Johnson
2010Journal of pharmacological and toxicological methods61 citations
Semantic Scholar
Recent Developments in Vaccine Design: From Live Vaccines to Recombinant Toxin Vaccines
Sonal Gupta, S. Pellett
2023Toxins59 citations Open access
Semantic Scholar
Plasmid encoded neurotoxin genes in Clostridium botulinum serotype A subtypes.
K. Marshall, M. Bradshaw, S. Pellett, E. Johnson
2007Biochemical and Biophysical Research Communications - BBRC52 citations Open access
Semantic Scholar
Purification and Characterization of Botulinum Neurotoxin FA from a Genetically Modified Clostridium botulinum Strain
S. Pellett, W. Tepp, M. Bradshaw, Suzanne R. Kalb +7 more
2016Msphere49 citations Open access
Semantic Scholar
Evaluation of adamantane hydroxamates as botulinum neurotoxin inhibitors: synthesis, crystallography, modeling, kinetic and cellular based studies
Peter Šilhár, N. Silvaggi, S. Pellett, K. Čapková +3 more
2012Bioorganic & Medicinal Chemistry46 citations Open access
Semantic Scholar
Critical Analysis of Neuronal Cell and the Mouse Bioassay for Detection of Botulinum Neurotoxins
S. Pellett, W. Tepp, E. Johnson
2019Toxins31 citations Open access
Semantic Scholar
Comparison of the Catalytic Properties of the Botulinum Neurotoxin subtypes A1 and A5
Dongxia Wang, Joan C Krilich, S. Pellett, Jakub Baudys +4 more
2013Biochimica et Biophysica Acta31 citations Open access
Semantic Scholar
Sensitive and quantitative detection of botulinum neurotoxin in neurons derived from mouse embryonic stem cells
S. Pellett, Zhongwei Du, Christina L. Pier, W. Tepp +2 more
2010Biochemical and Biophysical Research Communications - BBRC31 citations Open access
Semantic Scholar
Human Induced Pluripotent Stem Cell Derived Neuronal Cells Cultured on Chemically-Defined Hydrogels for Sensitive In Vitro Detection of Botulinum Neurotoxin
S. Pellett, Michael P. Schwartz, W. Tepp, R. Josephson +5 more
2015Scientific Reports29 citations Open access
Semantic Scholar
Benzylidene cyclopentenediones: First Irreversible Inhibitors against Botulinum Neurotoxin A’s Zinc Endopeptidase
K. Čapková, M. Hixon, S. Pellett, J. Barbieri +2 more
2009Bioorganic & Medicinal Chemistry Letters29 citations Open access
Semantic Scholar
Botulinum Neurotoxins A, B, C, E, and F preferentially enter cultured human motor neurons compared to other cultured human neuronal populations
S. Pellett, W. Tepp, Eric A. Johnson
2019FEBS Letters25 citations Open access
Semantic Scholar
Toosendanin: Synthesis of the AB-ring and Investigations of Its Anti-Botulinum Properties (Part II)
Y. Nakai, S. Pellett, W. Tepp, E. Johnson +1 more
2009Bioorganic & Medicinal Chemistry23 citations Open access
Semantic Scholar
Synthesis/biological evaluation of hydroxamic acids and their prodrugs as inhibitors for Botulinum neurotoxin A light chain
H. Seki, S. Pellett, Peter Šilhár, G. N. Stowe +4 more
2013Bioorganic & Medicinal Chemistry22 citations Open access
Semantic Scholar
Learning from the past: historical aspects of bacterial toxins as pharmaceuticals.
S. Pellett
2012Current Opinion in Microbiology22 citations
Semantic Scholar
Holotoxin Activity of Botulinum Neurotoxin Subtype A4 Originating from a Nontoxigenic Clostridium botulinum Expression System
M. Bradshaw, W. Tepp, Regina C. M. Whitemarsh, S. Pellett +1 more
2014Applied and Environmental Microbiology21 citations Open access
Semantic Scholar
Targeting Botulinum A Cellular Toxicity: A Prodrug Approach
Peter Šilhár, L. M. Eubanks, H. Seki, S. Pellett +4 more
2013Journal of Medicinal Chemistry21 citations Open access
Semantic Scholar
A Novel High-Potency Tetanus Vaccine
A. Przedpelski, W. Tepp, S. Pellett, E. Johnson +1 more
2020mBio20 citations Open access
Semantic Scholar
Isolation and Characterization of the Novel Botulinum Neurotoxin A Subtype 6
Molly S. Moritz, W. Tepp, M. Bradshaw, E. Johnson +1 more
2018Msphere20 citations Open access
Semantic Scholar
Assessment of ELISA as Endpoint in Neuronal Cell-based Assay for BoNT Detection using hiPSC derived neurons
S. Pellett, W. Tepp, E. Johnson, D. Sesardic
2017Journal of pharmacological and toxicological methods20 citations Open access
Semantic Scholar
Activity of botulinum neurotoxin type D (strain 1873) in human neurons
S. Pellett, W. Tepp, Jacob M. Scherf, Christina L. Pier +1 more
2015Toxicon20 citations Open access
Semantic Scholar
Rapid Immune Responses to a Botulinum Neurotoxin Hc Subunit Vaccine through In Vivo Targeting to Antigen-Presenting Cells
David M. White, S. Pellett, M. Jensen, W. Tepp +2 more
2011Infection and Immunity20 citations Open access
Semantic Scholar
Preclinical Evidence for the Role of Botulinum Neurotoxin A (BoNT/A) in the Treatment of Peripheral Nerve Injury
M. Adler, S. Pellett, Shashi K. Sharma, F. Lebeda +2 more
2022Microorganisms19 citations Open access
Semantic Scholar
Neuronal Targeting, Internalization, and Biological Activity of a Recombinant Atoxic Derivative of Botulinum Neurotoxin A
S. Pellett, W. Tepp, L. Stanker, P. Band +2 more
2011Biochemical and Biophysical Research Communications - BBRC19 citations Open access
Semantic Scholar
Catch and Anchor Approach to Combat both Toxicity and Longevity of Botulinum Toxin A
Lucy Lin, M. E. Olson, T. Sugane, Lewis D Turner +8 more
2020Journal of Medicinal Chemistry18 citations Open access
Semantic Scholar
Metal Ions Effectively Ablate the Action of Botulinum Neurotoxin A
Paul T. Bremer, S. Pellett, J. Carolan, W. Tepp +4 more
2017Journal of the American Chemical Society18 citations Open access
Semantic Scholar
Botulinum Neurotoxins Can Enter Cultured Neurons Independent of Synaptic Vesicle Recycling
S. Pellett, W. Tepp, Jacob M. Scherf, E. Johnson
2015PLoS ONE18 citations Open access
Semantic Scholar
Substrate Cleavage and Duration of Action of Botulinum Neurotoxin Type FA (“H, HA”)
S. Pellett, W. Tepp, Guangyun Lin, E. Johnson
2017Toxicon17 citations Open access
Semantic Scholar
Toward the discovery of dual inhibitors for botulinum neurotoxin A: concomitant targeting of endocytosis and light chain protease activity.
H. Seki, Song Xue, M. Hixon, S. Pellett +3 more
2015Chemical Communications17 citations
Semantic Scholar
Mak16p is required for the maturation of 25S and 5.8S rRNAs in the yeast Saccharomyces cerevisiae
S. Pellett, James W. Tracy
2006Yeast17 citations
Semantic Scholar
Cellular Protection of SNAP-25 against Botulinum Neurotoxin/A: Inhibition of Thioredoxin Reductase through a Suicide Substrate Mechanism
H. Seki, Song Xue, S. Pellett, Peter Šilhár +2 more
2016Journal of the American Chemical Society16 citations Open access
Semantic Scholar
Heat-Labile Enterotoxin IIa, a Platform To Deliver Heterologous Proteins into Neurons
Chen Chen, A. Przedpelski, W. Tepp, S. Pellett +2 more
2015mBio16 citations Open access
Semantic Scholar
Comparative functional analysis of mice after local injection with botulinum neurotoxin A1, A2, A6, and B1 by Catwalk Analysis
Molly S. Moritz, W. Tepp, Heather N'te Inzalaco, E. Johnson +1 more
2019Toxicon15 citations Open access
Semantic Scholar
A Study and Review of Effects of Botulinum Toxins on Mast Cell Dependent and Independent Pruritus
Roshni Ramachandran, Marc J. Marino, Snighdha Paul, Zhen-Ping Wang +5 more
2018Toxins15 citations Open access
Semantic Scholar
Model for Studying Clostridium botulinum Neurotoxin Using Differentiated Motor Neuron-like NG108-15 Cells
Regina C. M. Whitemarsh, Christina L. Pier, W. Tepp, S. Pellett +1 more
2012Biochemical and Biophysical Research Communications - BBRC13 citations Open access
Semantic Scholar
Selection and Characterization of a Human Monoclonal Neutralizing Antibody for Clostridium Botulinum Neurotoxin Serotype B
He-Yue Zhou, Bin Zhou, S. Pellett, E. Johnson +1 more
2008Bioorganic & Medicinal Chemistry Letters13 citations Open access
Semantic Scholar
Endogenous CRISPR-Cas Systems in Group I Clostridium botulinum and Clostridium sporogenes Do Not Directly Target the Botulinum Neurotoxin Gene Cluster
T. Wentz, B. J. Tremblay, M. Bradshaw, A. Doxey +3 more
2022Frontiers in Microbiology12 citations Open access
Semantic Scholar
Small Molecule Metalloprotease Inhibitor with in Vitro, Ex Vivo and In Vivo Efficacy Against Botulinum Neurotoxin Serotype A
A. Jacobson, M. Adler, N. Silvaggi, Karen N. Allen +14 more
2017Toxicon12 citations Open access
Semantic Scholar
Genomic Diversity, Competition, and Toxin Production by Group I and II Clostridium botulinum Strains Used in Food Challenge Studies
B. Bowe, T. Wentz, Brieana M. Gregg, W. Tepp +3 more
2022Microorganisms11 citations Open access
Semantic Scholar
Identification of divergent botulinum neurotoxin homologs in Paeniclostridium ghonii
Xin Wei, T. Wentz, B. Lobb, Michael J. Mansfield +6 more
2022bioRxiv10 citations Open access
Semantic Scholar

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