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C. Waddington · SciRah

Researcher profile · Semantic Scholar

C. Waddington

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C. Waddington — researcher profile on SciRah

h-index: 26
Works: 79
Citations: 1,854

Most-cited papers

Safety and immunogenicity of AS03B adjuvanted split virion versus non-adjuvanted whole virion H1N1 influenza vaccine in UK children aged 6 months-12 years: open label, randomised, parallel group, multicentre study
C. Waddington, W. Walker, C. Oeser, A. Reiner +18 more
2010British medical journal169 citations Open access
Semantic Scholar
An Outpatient, Ambulant-Design, Controlled Human Infection Model Using Escalating Doses of Salmonella Typhi Challenge Delivered in Sodium Bicarbonate Solution
C. Waddington, T. Darton, Claire Jones, K. Haworth +15 more
2014Clinical Infectious Diseases145 citations Open access
Semantic Scholar
Susceptibility to and transmission of COVID-19 amongst children and adolescents compared with adults: a systematic review and meta-analysis
R. Viner, O. Mytton, C. Bonell, G. Meléndez-Torres +12 more
2020medRxiv87 citations Open access
Semantic Scholar
Exploiting genomics to mitigate the public health impact of antimicrobial resistance
C. Waddington, M. Carey, Christine J. Boinett, E. Higginson +2 more
2022Genome Medicine77 citations Open access
Semantic Scholar
Evaluation of the Clinical and Microbiological Response to Salmonella Paratyphi A Infection in the First Paratyphoid Human Challenge Model
H. Dobinson, M. Gibani, Claire Jones, H. Thomaides-Brears +20 more
2017Clinical Infectious Diseases77 citations Open access
Semantic Scholar
Using a Human Challenge Model of Infection to Measure Vaccine Efficacy: A Randomised, Controlled Trial Comparing the Typhoid Vaccines M01ZH09 with Placebo and Ty21a
T. Darton, Claire Jones, Christoph J. Blohmke, C. Waddington +19 more
2016PLoS Neglected Tropical Diseases76 citations Open access
Semantic Scholar
Challenge of Humans with Wild-type Salmonella enterica Serovar Typhi Elicits Changes in the Activation and Homing Characteristics of Mucosal-Associated Invariant T Cells
R. Salerno-Gonçalves, David Luo, S. Fresnay, L. Magder +8 more
2017Frontiers in Immunology64 citations Open access
Semantic Scholar
Salmonella Typhi-specific multifunctional CD8+ T cells play a dominant role in protection from typhoid fever in humans
S. Fresnay, Monica A. McArthur, L. Magder, T. Darton +7 more
2016Journal of Translational Medicine64 citations Open access
Semantic Scholar
A controlled human infection model of Streptococcus pyogenes pharyngitis (CHIVAS-M75): an observational, dose-finding study.
J. Osowicki, Kristy I Azzopardi, Loraine Fabri, H. Frost +22 more
2021The Lancet Microbe61 citations Open access
Semantic Scholar
The challenge of enteric fever.
C. Waddington, T. Darton, A. Pollard
2014Journal of Infection59 citations
Semantic Scholar
Management of invasive group A streptococcal infections.
C. Waddington, T. Snelling, J. Carapetis
2014Journal of Infection59 citations
Semantic Scholar
Point of Care Nucleic Acid Testing for SARS-CoV-2 in Hospitalized Patients: A Clinical Validation Trial and Implementation Study
Dami A. Collier, S. Assennato, B. Warne, Nyaradzai Sithole +72 more
2020Cell Reports Medicine53 citations Open access
Semantic Scholar
Activation of Salmonella Typhi-Specific Regulatory T Cells in Typhoid Disease in a Wild-Type S. Typhi Challenge Model
Monica A. McArthur, S. Fresnay, L. Magder, T. Darton +8 more
2015PLoS Pathogens53 citations Open access
Semantic Scholar
Advancing the management and control of typhoid fever: a review of the historical role of human challenge studies.
C. Waddington, T. Darton, W. E. Woodward, B. Angus +2 more
2014Journal of Infection52 citations
Semantic Scholar
Use of cidofovir in a patient with severe mpox and uncontrolled HIV infection
Adam Stafford, S. Rimmer, M. Gilchrist, Kristi Sun +24 more
2023Lancet. Infectious Diseases (Print)49 citations Open access
Semantic Scholar
Working towards a group A streptococcal vaccine: report of a collaborative Trans-Tasman workshop.
N. Moreland, C. Waddington, D. Williamson, S. Sriskandan +10 more
2014Vaccine47 citations
Semantic Scholar
Interferon-driven alterations of the host’s amino acid metabolism in the pathogenesis of typhoid fever
Christoph J. Blohmke, T. Darton, Claire Jones, N. Suárez +23 more
2016Journal of Experimental Medicine46 citations Open access
Semantic Scholar
Rapidly Escalating Hepcidin and Associated Serum Iron Starvation Are Features of the Acute Response to Typhoid Infection in Humans
T. Darton, Christoph J. Blohmke, E. Giannoulatou, C. Waddington +6 more
2015PLoS Neglected Tropical Diseases46 citations Open access
Semantic Scholar
Controlled human infection for vaccination against Streptococcus pyogenes (CHIVAS): Establishing a group A Streptococcus pharyngitis human infection study.
J. Osowicki, Kristy I Azzopardi, C. Baker, C. Waddington +13 more
2019Vaccine43 citations Open access
Semantic Scholar
Blood culture-PCR to optimise typhoid fever diagnosis after controlled human infection identifies frequent asymptomatic cases and evidence of primary bacteraemia
T. Darton, Liqing Zhou, Christoph J. Blohmke, Claire Jones +3 more
2017Journal of Infection43 citations Open access
Semantic Scholar
Midwives' attitudes, beliefs and concerns about childhood vaccination: A review of the global literature.
Katie Attwell, K. Wiley, C. Waddington, J. Leask +1 more
2018Vaccine42 citations
Semantic Scholar
Facial Nerve Palsy Complicating Kawasaki Disease
H. Wright, C. Waddington, J. Geddes, J. Newburger +1 more
2008Pediatrics42 citations
Semantic Scholar
Predictors of immune response and reactogenicity to AS03B-adjuvanted split virion and non-adjuvanted whole virion H1N1 (2009) pandemic influenza vaccines.
N. Andrews, W. Walker, A. Finn, P. Heath +22 more
2011Vaccine35 citations Open access
Semantic Scholar
Importance of Salmonella Typhi-Responsive CD8+ T Cell Immunity in a Human Typhoid Fever Challenge Model
S. Fresnay, Monica A. McArthur, L. Magder, T. Darton +7 more
2017Frontiers in Immunology34 citations Open access
Semantic Scholar
Oral Wild-Type Salmonella Typhi Challenge Induces Activation of Circulating Monocytes and Dendritic Cells in Individuals Who Develop Typhoid Disease
F. Toapanta, P. Bernal, S. Fresnay, T. Darton +8 more
2015PLoS Neglected Tropical Diseases30 citations Open access
Semantic Scholar
Prospects for prevention of Salmonella infection in children through vaccination
A. McGregor, C. Waddington, A. Pollard
2013Current Opinion in Infectious Diseases29 citations
Semantic Scholar
Modeling COVID-19 disease processes by remote elicitation of causal Bayesian networks from medical experts
S. Mascaro, Yue Wu, O. Woodberry, Erik P. Nyberg +32 more
2022BMC Medical Research Methodology20 citations Open access
Semantic Scholar
Whole cell pertussis vaccination and decreased risk of IgE-mediated food allergy: a nested case-control study.
M. Estcourt, D. Campbell, M. Gold, P. Richmond +11 more
2019Journal of Allergy and Clinical Immunology: In Practice20 citations
Semantic Scholar
SMS-based interventions for improving child and adolescent vaccine coverage and timeliness: a systematic review
George Currie, C. Mcleod, C. Waddington, T. Snelling
2024BMC Public Health18 citations Open access
Semantic Scholar
The ORVAC trial protocol: a phase IV, double-blind, randomised, placebo-controlled clinical trial of a third scheduled dose of Rotarix rotavirus vaccine in Australian Indigenous infants to improve protection against gastroenteritis
B. Middleton, Mark A. Jones, C. Waddington, M. Danchin +9 more
2019BMJ Open18 citations Open access
Semantic Scholar
Oral Challenge with Wild-Type Salmonella Typhi Induces Distinct Changes in B Cell Subsets in Individuals Who Develop Typhoid Disease
F. Toapanta, P. Bernal, S. Fresnay, L. Magder +8 more
2016PLoS Neglected Tropical Diseases17 citations Open access
Semantic Scholar
Identification of the determinants of incomplete vaccination in Australian children
Christopher E. Lim, Grace E. Currie, C. Waddington, Yue Wu +4 more
2019Vaccine: X16 citations Open access
Semantic Scholar
Rapid point of care nucleic acid testing for SARS-CoV-2 in hospitalised patients: a clinical trial and implementation study
Dami A. Collier, S. Assennato, B. Warne, N. Sithole +28 more
2020medRxiv15 citations Open access
Semantic Scholar
Informing rubella vaccination strategies in East Java, Indonesia through transmission modelling.
Yue Wu, J. Wood, G. Khandaker, C. Waddington +1 more
2016Vaccine15 citations Open access
Semantic Scholar
Utilizing Rapid Multiple-Locus Variable-Number Tandem-Repeat Analysis Typing To Aid Control of Hospital-Acquired Clostridium difficile Infection: a Multicenter Study
K. Hardy, S. Manzoor, C. Marriott, H. Parsons +5 more
2012Journal of Clinical Microbiology15 citations Open access
Semantic Scholar
Mucosal-Associated Invariant T cells exhibit distinct functional signatures associated with protection against typhoid fever
R. Salerno-Gonçalves, S. Fresnay, L. Magder, T. Darton +6 more
2022Cellular Immunology12 citations Open access
Semantic Scholar
Genetic Susceptibility to Enteric Fever in Experimentally Challenged Human Volunteers
A. Barton, J. Hill, S. Bibi, Li-Ye Chen +11 more
2021bioRxiv10 citations Open access
Semantic Scholar
Factors influencing participation in controlled human infection models: a pooled analysis from six enteric fever studies
B. Oguti, M. Gibani, Christopher A. Darlow, C. Waddington +6 more
2019Wellcome Open Research10 citations Open access
Semantic Scholar
The NICE-GUT trial protocol: a randomised, placebo controlled trial of oral nitazoxanide for the empiric treatment of acute gastroenteritis among Australian Aboriginal children
C. Waddington, C. McLeod, P. Morris, A. Bowen +12 more
2018BMJ Open10 citations Open access
Semantic Scholar
Assessment and Translation of the Antibody-in-Lymphocyte Supernatant (ALS) Assay to Improve the Diagnosis of Enteric Fever in Two Controlled Human Infection Models and an Endemic Area of Nepal
T. Darton, Claire Jones, S. Dongol, M. Voysey +11 more
2017Frontiers in Microbiology10 citations Open access
Semantic Scholar
OPTIMUM study protocol: an adaptive randomised controlled trial of a mixed whole-cell/acellular pertussis vaccine schedule
Gladymar Perez Chacon, M. Estcourt, J. Totterdell, D. Campbell +8 more
2020BMJ Open8 citations Open access
Semantic Scholar
Perinatal Risk Factors Associated With Gastroenteritis Hospitalizations in Aboriginal and Non-Aboriginal Children in Western Australia (2000–2012): A Record Linkage Cohort Study
P. Fathima, T. Snelling, N. de Klerk, D. Lehmann +3 more
2019The Pediatric Infectious Disease Journal8 citations Open access
Semantic Scholar
Immunogenicity, reactogenicity, and IgE-mediated immune responses of a mixed whole-cell and acellular pertussis vaccine schedule in Australian infants: A randomised, double-blind, noninferiority trial
Gladymar Pérez Chacón, M. Estcourt, J. Totterdell, J. Marsh +13 more
2024PLoS Medicine7 citations Open access
Semantic Scholar
Past, present, and future of Phase 3 vaccine trial design: rethinking statistics for the 21st century
Leila Janani, Rachel Phillips, Eleanor Van Vogt, Xin-Xue Liu +2 more
2024Clinical and Experimental Immunology6 citations Open access
Semantic Scholar
Human Salmonella Typhi exposure generates differential multifunctional cross‐reactive T‐cell memory responses against Salmonella Paratyphi and invasive nontyphoidal Salmonella
R. R. Rapaka, R. Wahid, S. Fresnay, Jayaum S. Booth +6 more
2020Clinical & Translational Immunology6 citations Open access
Semantic Scholar
Molecular Diagnosis of Enteric Fever: Progress and Perspectives
Liqing Zhou, T. Darton, C. Waddington, A. Pollard
20126 citations Open access
Semantic Scholar
Changes in monocyte subsets in volunteers who received an oral wild-type Salmonella Typhi challenge and reached typhoid diagnosis criteria
F. Toapanta, Jingping Hu, K. Shirey, Paula J. Bernal +5 more
2024Frontiers in Immunology4 citations Open access
Semantic Scholar
Exploring the views of infection consultants in England on a novel delinked funding model for antimicrobials: the SMASH study
I. Baltas, M. Gilchrist, E. Koutoumanou, M. Gibani +36 more
2023JAC-Antimicrobial Resistance4 citations Open access
Semantic Scholar
Role of circulating T follicular helper subsets following Ty21a immunization and oral challenge with wild type S. Typhi in humans
Jayaum S. Booth, R. R. Rapaka, Monica A. McArthur, S. Fresnay +7 more
2024Frontiers in Immunology3 citations Open access
Semantic Scholar
Early transcriptional responses to human enteric fever challenge
A. Barton, J. Hill, D. O'Connor, Claire Jones +10 more
2023Infection and Immunity3 citations Open access
Semantic Scholar

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