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D. Forrest · SciRah

Researcher profile · Semantic Scholar

D. Forrest

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D. Forrest — researcher profile on SciRah

h-index: 30
Works: 170
Citations: 2,978

Most-cited papers

The core autophagy protein ATG4B is a potential biomarker and therapeutic target in CML stem/progenitor cells.
K. Rothe, Hanyang Lin, Kevin B. L. Lin, Amy Leung +6 more
2014Blood195 citations Open access
Semantic Scholar
Patients with myeloid malignancies bearing PDGFRB fusion genes achieve durable long-term remissions with imatinib.
Che-Ah Y. Chan, K. Burbury, J. Apperley, F. Huguet +15 more
2014Blood144 citations Open access
Semantic Scholar
Targeting Primitive Chronic Myeloid Leukemia Cells by Effective Inhibition of a New AHI-1–BCR-ABL–JAK2 Complex
Min Chen, P. Gallipoli, Donna DeGeer, I. Sloma +18 more
2013Journal of the National Cancer Institute88 citations Open access
Semantic Scholar
Properties of CD34+ CML stem/progenitor cells that correlate with different clinical responses to imatinib mesylate.
Xiao-Yan Jiang, D. Forrest, F. Nicolini, A. Turhan +15 more
2010Blood72 citations Open access
Semantic Scholar
Outcome of Patients With Non-Hodgkin Lymphomas With Concurrent MYC and BCL2 Rearrangements Treated With CODOX-M/IVAC With Rituximab Followed by Hematopoietic Stem Cell Transplantation.
H. Sun, K. Savage, A. Karsan, G. Slack +18 more
2015Clinical Lymphoma, Myeloma & Leukemia48 citations
Semantic Scholar
The miR-185/PAK6 Axis Predicts Therapy Response and Regulates Survival of Drug-Resistant Leukemic Stem Cells in CML.
Hanyang Lin, K. Rothe, Min Chen, A. Wu +16 more
2020Blood46 citations Open access
Semantic Scholar
Integrin-Linked Kinase Mediates Therapeutic Resistance of Quiescent CML Stem Cells to Tyrosine Kinase Inhibitors.
K. Rothe, A. Babaian, N. Nakamichi, Min Chen +7 more
2020Cell Stem Cell45 citations Open access
Semantic Scholar
PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL+ human leukemia
Damian Lai, Min Chen, Jie-Chuang Su, Xiaohu Liu +6 more
2018Science Translational Medicine44 citations
Semantic Scholar
Novel agents improve survival of transplant patients with multiple myeloma including those with high-risk disease defined by early relapse (<12 months)
C. Venner, J. Connors, H. Sutherland, J. Shepherd +14 more
2011Leukemia and Lymphoma35 citations
Semantic Scholar
Allogeneic haematopoietic stem cell transplantation for chronic lymphocytic leukaemia: outcome in a 20‐year cohort
C. Toze, Chinmay B. Dalal, T. Nevill, T. Gillan +14 more
2012British Journal of Haematology27 citations
Semantic Scholar
A novel AHI-1–BCR-ABL–DNM2 complex regulates leukemic properties of primitive CML cells through enhanced cellular endocytosis and ROS-mediated autophagy
Xiaohu Liu, K. Rothe, R. Yen, C. Fruhstorfer +5 more
2017Leukemia26 citations Open access
Semantic Scholar
Second Attempt of TKI Discontinuation with Dasatinib for Treatment-Free Remission after Failing First Attempt with Imatinib: Treatment-Free Remission Accomplished By Dasatinib (TRAD) Trial
D. Kim, L. Busque, D. Forrest, L. Savoie +10 more
2018Blood24 citations Open access
Semantic Scholar
Excellent real‐world outcomes of adults with Burkitt lymphoma treated with CODOX‐M/IVAC plus or minus rituximab
K. Zhu, K. Song, J. Connors, H. Leitch +17 more
2018British Journal of Haematology24 citations Open access
Semantic Scholar
Allogeneic Hematopoietic Stem Cell Transplantation Is an Effective Salvage Therapy for Patients with Chronic Myeloid Leukemia Presenting with Advanced Disease or Failing Treatment with Tyrosine Kinase Inhibitors.
A. P. Nair, M. Barnett, R. Broady, D. Hogge +10 more
2015Biology of Blood and Marrow Transplantation23 citations Open access
Semantic Scholar
Two cases of platelet transfusion refractoriness associated with anti‐CD36
C. Saw, H. Szykoluk, B. R. Curtis, S. Zelcer +5 more
2010Transfusion22 citations
Semantic Scholar
Improving Revised International Prognostic Scoring System Pre-Allogeneic Stem Cell Transplantation Does Not Translate Into Better Post-Transplantation Outcomes for Patients with Myelodysplastic Syndromes: A Single-Center Experience.
M. Alzahrani, M. Power, Y. A. Abou Mourad, Michael L. Barnett +11 more
2018Biology of Blood and Marrow Transplantation20 citations Open access
Semantic Scholar
High-dose melphalan followed by auto-SCT has favorable safety and efficacy in selected patients with light chain deposition disease and light and heavy chain deposition disease
D. Telio, J. Shepherd, D. Forrest, L. Zypchen +3 more
2012Bone Marrow Transplantation20 citations Open access
Semantic Scholar
Long-term follow-up of patients with chronic myeloid leukemia in chronic phase developing sudden blast phase on imatinib therapy
A. Tantiworawit, M. Power, M. Barnett, D. Hogge +10 more
2012Leukemia and Lymphoma19 citations
Semantic Scholar
Outpatient Autologous Stem Cell Transplants for Multiple Myeloma: Analysis of Safety and Outcomes in a Tertiary Care Center.
S. Kodad, H. Sutherland, W. Limvorapitak, Y. A. Abou Mourad +13 more
2019Clinical Lymphoma, Myeloma & Leukemia17 citations
Semantic Scholar
Optimal duration of imatinib treatment/deep molecular response for treatment‐free remission after imatinib discontinuation from a Canadian tyrosine kinase inhibitor discontinuation trial
D. Kim, I. Novitzky-Basso, TaeHyung Kim, E. Atenafu +14 more
2021British Journal of Haematology15 citations
Semantic Scholar
Treatment-Free Remission Accomplished By Dasatinib (TRAD): Preliminary Results of the Pan-Canadian Tyrosine Kinase Inhibitor Discontinuation Trial
D. Kim, I. Bence-Bruckler, D. Forrest, M. L. Savoie +10 more
201615 citations
Semantic Scholar
Outcome Of Patients With Double-Hit Lymphomas Treated With CODOX-M/IVAC + R Followed By Hematopoietic Stem Cell Transplantation In British Columbia
H. Sun, K. Savage, A. Karsan, G. Slack +18 more
201315 citations
Semantic Scholar
Outcomes of Intermediate Risk Karyotype Acute Myeloid Leukemia in First Remission Undergoing Autologous Stem Cell Transplantation Compared With Allogeneic Stem Cell Transplantation and Chemotherapy Consolidation: A Retrospective, Propensity‐score Adjusted Analysis
W. Limvorapitak, M. Barnett, D. Hogge, D. Forrest +12 more
2018Clinical Lymphoma, Myeloma & Leukemia14 citations
Semantic Scholar
Incidence and socioeconomic factors in older adults with acute myeloid leukaemia: Real‐world outcomes from a population‐based cohort
Ryan J. Stubbins, M. Stamenkovic, C. Roy, J. Rodrigo +15 more
2022European Journal of Haematology12 citations
Semantic Scholar
Identification of key microRNAs as predictive biomarkers of Nilotinib response in chronic myeloid leukemia: a sub-analysis of the ENESTxtnd clinical trial
R. Yen, S. Grasedieck, A. Wu, Hanyang Lin +6 more
2022Leukemia12 citations
Semantic Scholar
Genotypic and functional diversity of phenotypically defined primitive hematopoietic cells in patients with chronic myeloid leukemia.
I. Sloma, P. Beer, Kyi Min Saw, M. Chan +8 more
2013Experimental Hematology11 citations Open access
Semantic Scholar
Optimal Duration of Imatinib Treatment / Deep Molecular Response for Treatment-Free Remission after Imatinib Discontinuation from a Canadian Tyrosine Kinase Inhibitor Discontinuation Trial
D. Kim, I. Novitzky-Basso, TaeHyung Kim, E. Atenafu +14 more
202010 citations
Semantic Scholar
Sorafenib is effective for imatinib-resistant FIP1L1/PDGFRA T674I mutation-positive acute myeloid leukemia with eosinophilia
A. Al-Riyami, M. Hudoba, Sean S. Young, D. Forrest
2013Leukemia and Lymphoma10 citations
Semantic Scholar
Achievement and Maintenance Of Deeper Molecular Response By Switching To Nilotinib In Patients (pts) With Chronic Myeloid Leukemia In Chronic Phase (CML-CP) With Residual Disease On Long-Term Imatinib: ENESTcmr 36-Month Follow-Up
F. Cervantes, N. Spector, J. Lipton, G. Étienne +9 more
20138 citations
Semantic Scholar
Outcomes with allogeneic stem cell transplant using cryopreserved versus fresh hematopoietic progenitor cell products.
Bo A. Wan, Lorenzo Lindo, Y. A. Mourad, S. Chung +15 more
2024Cytotherapy7 citations Open access
Semantic Scholar
Comparison of a pediatric-inspired treatment protocol versus standard-intensity chemotherapy for young adults with standard-risk BCR-ABL negative acute lymphoblastic leukemia
D. Kliman, Michael L. Barnett, R. Broady, D. Forrest +11 more
2017Leukemia and Lymphoma7 citations
Semantic Scholar
Autologous Stem Cell Transplant Outcome in Classic Hodgkin Lymphoma Patients in the Era of Post-Transplant Brentuximab Vedotin Consolidation
S. Chung, J. White, C. Toze, H. Sutherland +11 more
2021Blood4 citations Open access
Semantic Scholar
Response to Comment on “PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL+ human leukemia”
Damian Lai, Min Chen, Jie-Chuang Su, Xiaohu Liu +6 more
2019Science Translational Medicine4 citations
Semantic Scholar
Outpatient Autologous Stem Cell Transplants for Multiple Myeloma—Analysis of Safety and Outcomes in a Tertiary Care Centre
S. Kodad, H. Sutherland, W. Limvorapitak, Y. A. Mourad +13 more
20184 citations Open access
Semantic Scholar
High Induction Response Rate, but Poor Long-Term Disease Free Survival in Elderly Patients Treated Aggressively for Acute Lymphoblastic Leukemia
A. Tantiworawit, W. Rajkhan, M. Barnett, J. Shepherd +12 more
20144 citations
Semantic Scholar
Pediatric-Based Versus Adult Treatment Protocols in Young Adults (18-40 years) with Standard Risk Acute Lymphoblastic Leukemia: The BC Cancer Agency Experience
D. Kliman, M. Barnett, R. Broady, D. Forrest +10 more
20153 citations Open access
Semantic Scholar
Improved Survival In Adults With Mixed-Phenotype Acute Leukemia Following Stem Cell Transplantation (SCT): A Single Centre Experience
Mallikarjun Kalashetty, B. Dalal, Kristine Roland, Y. A. Mourad +13 more
20133 citations
Semantic Scholar
Elderly AML Patients Treated with Intensive Chemotherapy- Developing A Prognostic Scoring System. A Study On 381 Patients From British Columbia
S. Krishnan, Hui-Hua Li, Y. A. Abou Mourad, M. Barnett +11 more
20113 citations
Semantic Scholar
Outcomes Following Second Allogeneic Stem Cell Transplant for Graft Failure or Poor Graft Function: A Single Centre Experience
J. L. Kim, Moss A. Bruton Joe, S. Chung, Hannah Cherniawsky +14 more
2025Stem Cell Reviews and Reports2 citations Open access
Semantic Scholar
Improvement in Survival of Patients with FLT3 Mutated Acute Myeloid Leukemia: Results from a Retrospective Canadian Cohort
Shouriyo Ghosh, F. Kuchenbauer, Ryan J. Stubbins, S. Chung +13 more
2023Blood2 citations
Semantic Scholar
Mortality from Multiple Myeloma Within One Year Following Autologous Stem Cell Transplantation: Defining an Ultra-high Risk Population.
Hannah Cherniawsky, Hatem Alahwal, Y. A. Mourad, D. Forrest +12 more
2021Clinical Lymphoma, Myeloma & Leukemia2 citations
Semantic Scholar
Day 14 Bone Marrow Evaluation During Acute Myeloid Leukemia Induction in a Real-world Canadian Cohort.
J. England, Lalit Saini, D. Hogge, D. Forrest +8 more
2020Clinical Lymphoma, Myeloma & Leukemia2 citations
Semantic Scholar
Comprehensive Analysis of Hematological Parameter Changes after TKI Discontinuation for Treatment-Free Remission Attempt
Georgina S. Daher-Reyes, I. Bence-Bruckler, L. Busque, D. Forrest +11 more
2019Blood2 citations
Semantic Scholar
Inhibiting the Core Autophagy Enzyme ATG4B with Novel Drugs Sensitizes Resistant Leukemic Stem/Progenitor Cells to Standard Targeted Therapy
K. Rothe, Akie Watanabe, D. Forrest, S. Gorski +2 more
2018Blood2 citations
Semantic Scholar
Identification of a Unique Autophagy Gene Expression Signature in CD34+ CML Stem/Progenitor Cells That Correlates with Clinical Response to Imatinib Mesylate
K. Rothe, Kevin B. L. Lin, Hanyang Lin, Amy Leung +3 more
20122 citations
Semantic Scholar
Clonal Evolution but Not Variant Chromosomal Translocations Is An Adverse Prognostic Marker for Cytogenetic Response and Survival in CML Patients Treated with Imatinib
A. Tantiworawit, Y. A. Mourad, M. Barnett, R. Broady +10 more
20112 citations
Semantic Scholar
Long-term follow-up of patients undergoing auto-SCT for advanced germ cell tumour: a multicentre cohort study
Matthew D. Seftel, K. Paulson, R. Doocey, K. Song +13 more
2011Bone Marrow Transplantation2 citations
Semantic Scholar
Clinical Outcomes in Fresh Versus Cryopreserved Hematopoietic Stem Cell Products in British Columbia: A Retrospective Study
Bo Wan, Lorenzo Lindo, G. Cameron, Y. A. Abou Mourad +16 more
2022Blood1 citations Open access
Semantic Scholar
BCR-ABL1 Transcript Doubling Time after Imatinib Discontinuation for Treatment-Free Remission in Chronic Myeloid Leukemia in Chronic Phase: Predictor for Treatment-Free Remission Failure
D. Kim, I. Novitzky-Basso, TaeHyung Kim, E. Atenafu +14 more
20201 citations
Semantic Scholar
BCR-ABL1 qPCR-Based Doubling Time within the First 6 Months after Imatinib Discontinuation Is a Predictive of Successful TKI Treatment-Free Remission
Georgina S. Daher-Reyes, I. Bence-Bruckler, L. Busque, D. Forrest +11 more
2019Blood1 citations Open access
Semantic Scholar

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