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L. Busque · SciRah

Researcher profile · Semantic Scholar

L. Busque

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L. Busque — researcher profile on SciRah

h-index: 41
Works: 207
Citations: 12K

Most-cited papers

The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms
J. Khoury, É. Solary, O. Abla, Yassmine M. N. Akkari +58 more
2022Leukemia3,838 citations Open access
Semantic Scholar
Clonal Hematopoiesis and Evolution to Hematopoietic Malignancies
Robert L. Bowman, L. Busque, R. Levine
2018Cell Stem Cell438 citations Open access
Semantic Scholar
Microbial signals drive pre–leukaemic myeloproliferation in a Tet2–deficient host
Marlies Meisel, Reinhard Hinterleitner, A. Pacis, Li Chen +27 more
2018Nature373 citations Open access
Semantic Scholar
DNMT3A and TET2 dominate clonal hematopoiesis and demonstrate benign phenotypes and different genetic predispositions.
M. Buscarlet, S. Provost, Y. F. Zada, A. Barhdadi +6 more
2017Blood355 citations Open access
Semantic Scholar
Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial
J. Tardif, N. Bouabdallaoui, L, Philippe L. Allier +41 more
2021The Lancet Respiratory Medicine215 citations Open access
Semantic Scholar
3023 Mayo Clinic Patients With Myeloproliferative Neoplasms: Risk‐Stratified Comparison of Survival and Outcomes Data Among Disease Subgroups
N. Szuber, M. Mudireddy, M. Nicolosi, D. Penna +15 more
2018Mayo Clinic proceedings169 citations
Semantic Scholar
Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1-2 safety and feasibility study.
S. Cohen, J. Roy, S. Lachance, J. Delisle +24 more
2019The Lancet Haematology153 citations
Semantic Scholar
Oral cedazuridine/decitabine: a phase 2, pharmacokinetic/pharmacodynamic, randomized, crossover study in MDS and CMML.
G. Garcia-Manero, E. Griffiths, D. Steensma, G. Roboz +13 more
2020Blood149 citations Open access
Semantic Scholar
Lineage restriction analyses in CHIP indicate myeloid bias for TET2 and multipotent stem cell origin for DNMT3A.
M. Buscarlet, S. Provost, Y. F. Zada, Vincent Bourgoin +3 more
2018Blood130 citations Open access
Semantic Scholar
Oral decitabine-cedazuridine versus intravenous decitabine for myelodysplastic syndromes and chronic myelomonocytic leukaemia (ASCERTAIN): a registrational, randomised, crossover, pharmacokinetics, phase 3 study.
G. Garcia-Manero, James K. McCloskey, Elizabeth A. Griffiths, Karen W. L. Yee +27 more
2024The Lancet Haematology86 citations
Semantic Scholar
High-sensitivity C-reactive protein is associated with clonal hematopoiesis of indeterminate potential.
L. Busque, Maxine Sun, M. Buscarlet, S. Ayachi +9 more
2020Blood Advances76 citations Open access
Semantic Scholar
Age-Related Clonal Hematopoiesis: Stem Cells Tempting the Devil
L. Busque, M. Buscarlet, L. Mollica, R. Levine
2018Stem Cells71 citations Open access
Semantic Scholar
Dasatinib dose optimisation based on therapeutic drug monitoring reduces pleural effusion rates in chronic myeloid leukaemia patients
P. Rousselot, L. Mollica, J. Guilhot, A. Guerci +21 more
2021British Journal of Haematology47 citations Open access
Semantic Scholar
Phenotypical differences and thrombosis rates in secondary erythrocytosis versus polycythemia vera
Eliane Nguyen, M. Harnois, L. Busque, Shireen Sirhan +5 more
2021Blood Cancer Journal32 citations Open access
Semantic Scholar
Macaque Clonal Hematopoiesis Model Demonstrates Expansion of TET2-Disrupted Clones and Utility for Testing Interventions.
Tae-Hoon Shin, Yifan Zhou, Shirley Chen, Stefan Cordes +23 more
2022Blood31 citations Open access
Semantic Scholar
60 years of clonal hematopoiesis research: from X-Chromosome Inactivation studies to the identification of driver mutations.
S. Ayachi, M. Buscarlet, L. Busque
2020Experimental Hematology31 citations Open access
Semantic Scholar
Blasts in context: the impact of the immune environment on acute myeloid leukemia prognosis and treatment.
Y. Serroukh, J. Hébert, L. Busque, F. Mercier +4 more
2022Blood reviews25 citations Open access
Semantic Scholar
Second Attempt of TKI Discontinuation with Dasatinib for Treatment-Free Remission after Failing First Attempt with Imatinib: Treatment-Free Remission Accomplished By Dasatinib (TRAD) Trial
D. Kim, L. Busque, D. Forrest, L. Savoie +10 more
2018Blood24 citations Open access
Semantic Scholar
UM171-expanded cord blood transplants support robust T cell reconstitution with low rates of severe infections.
M. Dumont-Lagacé, Qi Li, Mégane Tanguay, J. Chagraoui +20 more
2020Biology of Blood and Marrow Transplantation23 citations Open access
Semantic Scholar
Two types of human TCR differentially regulate reactivity to self and non-self antigens
Assya Trofimov, P. Brouillard, Jean-David Larouche, J. Séguin +8 more
2022bioRxiv22 citations Open access
Semantic Scholar
Clinical-Scale Rapid Autologous BK Virus-Specific T Cell Line Generation From Kidney Transplant Recipients With Active Viremia for Adoptive Immunotherapy
Caroline Lamarche, J. Orio, Victoria Georges-Tobar, T. Pincez +6 more
2017Transplantation22 citations
Semantic Scholar
Clinical Efficacy and Safety of Oral Decitabine/Cedazuridine in 133 Patients with Myelodysplastic Syndromes (MDS) and Chronic Myelomonocytic Leukemia (CMML)
M. Savona, James K. McCloskey, Elizabeth A. Griffiths, Karen W. L. Yee +25 more
2020Blood20 citations Open access
Semantic Scholar
Rationale, design, and preliminary results of the Quebec Warfarin Cohort Study
S. Perreault, P. Shahabi, R. Côté, Stéphanie Dumas +19 more
2018Clinical Cardiology20 citations Open access
Semantic Scholar
Allodepleted T‐cell immunotherapy after haploidentical haematopoietic stem cell transplantation without severe acute graft‐versus‐host disease (GVHD) in the absence of GVHD prophylaxis
D. Roy, S. Lachance, S. Cohen, J. Delisle +12 more
2019British Journal of Haematology19 citations Open access
Semantic Scholar
A Phase 2 Dose-Confirmation Study of Oral ASTX727, a Combination of Oral Decitabine with a Cytidine Deaminase Inhibitor (CDAi) Cedazuridine (E7727), in Subjects with Myelodysplastic Syndromes (MDS)
G. Garcia-Manero, E. Griffiths, G. Roboz, L. Busque +12 more
201718 citations
Semantic Scholar
Canadian real-world experience of asciminib treatment in heavily pre-treated chronic myeloid leukemia (CML) patients who failed multiple lines of tyrosine kinase inhibitor (TKI) therapy.
F. Khadadah, Sonia Cerquozzi, H. Olney, Christina G S Fraga +13 more
2023Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis16 citations
Semantic Scholar
Final report of TKI discontinuation trial with dasatinib for the second attempt of treatment‐free remission after failing the first attempt with imatinib: Treatment‐free Remission Accomplished by Dasatinib (TRAD) study
M. Perusini, I. Novitzky-Basso, E. Atenafu, D. Forrest +13 more
2023British Journal of Haematology15 citations
Semantic Scholar
Optimal duration of imatinib treatment/deep molecular response for treatment‐free remission after imatinib discontinuation from a Canadian tyrosine kinase inhibitor discontinuation trial
D. Kim, I. Novitzky-Basso, TaeHyung Kim, E. Atenafu +14 more
2021British Journal of Haematology15 citations
Semantic Scholar
Imatinib mesylate inhibits STAT5 phosphorylation in response to IL-7 and promotes T cell lymphopenia in chronic myelogenous leukemia patients
S. Thiant, M. M. Moutuou, P. Laflamme, R. Boumedine +4 more
2017Blood Cancer Journal14 citations Open access
Semantic Scholar
The safety and efficacy of dasatinib plus nivolumab in patients with previously treated chronic myeloid leukemia: results from a phase 1b dose-escalation study
J. Martínez-López, S. Mustjoki, K. Porkka, Rebecca B. Klisovic +6 more
2021Leukemia and Lymphoma13 citations
Semantic Scholar
Natural spring water gargle samples as an alternative to nasopharyngeal swabs for SARS‐CoV‐2 detection using a laboratory‐developed test
Sarah Gobeille Paré, J. Bestman-Smith, J. Fafard, F. Doualla-Bell +13 more
2021Journal of Medical Virology12 citations Open access
Semantic Scholar
Prolonged Survival in Bi-Allelic TP53-Mutated (TP53mut) MDS Subjects Treated with Oral Decitabine/Cedazuridine in the Ascertain Trial (ASTX727-02)
M. Savona, J. Mccloskey, E. Griffiths, K. Yee +26 more
2022Blood11 citations
Semantic Scholar
Identification of the genetic determinants responsible for retinal degeneration in families of Mexican descent
Adda L. Villanueva, P. Biswas, Kameron Kishaba, John Suk +12 more
2017Ophthalmic Genetics11 citations Open access
Semantic Scholar
The associations of hostility and defensiveness with telomere length are influenced by sex and health status
L. Starnino, G. Dupuis, L. Busque, Vincent Bourgoin +3 more
2021Biology of Sex Differences10 citations Open access
Semantic Scholar
Oral Decitabine/Cedazuridine in Patients with Lower Risk Myelodysplastic Syndrome: A Longer-Term Follow-up of from the Ascertain Study
G. Garcia-Manero, J. Mccloskey, E. Griffiths, K. Yee +25 more
2021Blood10 citations Open access
Semantic Scholar
Optimal Duration of Imatinib Treatment / Deep Molecular Response for Treatment-Free Remission after Imatinib Discontinuation from a Canadian Tyrosine Kinase Inhibitor Discontinuation Trial
D. Kim, I. Novitzky-Basso, TaeHyung Kim, E. Atenafu +14 more
202010 citations
Semantic Scholar
Persistence with generic imatinib for chronic myeloid leukemia: a matched cohort study
A. Klil-Drori, Hui Yin, L. Azoulay, M. Harnois +3 more
2019Haematologica10 citations Open access
Semantic Scholar
S159: QUÉBEC CML RESEARCH GROUP ANALYSIS OF TREATMENT PATTERNS IN CHRONIC MYELOGENOUS LEUKEMIA: SWITCHING IS DRIVEN BY INTOLERANCE AND SIMILAR ACROSS TYROSINE KINASE INHIBITORS AND LINES OF TREATMENT
L. Busque, M. Harnois, N. Szuber, R. Delage +11 more
2022HemaSphere9 citations Open access
Semantic Scholar
BCR–ABL1 transcript doubling time as a predictor for treatment‐free remission failure after imatinib discontinuation in chronic myeloid leukaemia in chronic phase
D. Kim, TaeHyung Kim, E. Atenafu, I. Novitzky-Basso +14 more
2021British Journal of Haematology9 citations Open access
Semantic Scholar
Risk of progression in chronic phase‐chronic myeloid leukemia patients eligible for tyrosine kinase inhibitor discontinuation: Final analysis of the TFR‐PRO study
G. Zambrotta, F. Nicolini, S. Assouline, L. Busque +24 more
2023American journal of hematology/oncology8 citations Open access
Semantic Scholar
Somatic Mosaic Chromosomal Alterations and Death of Cardiovascular Disease Causes among Cancer Survivors
Maxine Sun, Marie-Christyne Cyr, J. Sandoval, Louis-Philippe Lemieux Perreault +3 more
2022medRxiv8 citations Open access
Semantic Scholar
P708: CANADIAN AND RUSSIAN EXPERIENCES OF ASCIMINIB IN CHRONIC MYELOID LEUKEMIA (CML) PATIENTS WHO FAILED MULTIPLE LINES OF TYROSINE KINASE INHIBITOR (TKI) THERAPY.
F. Khadadah, A. Turkina, E. Lomaia, E. Morozova +18 more
2022HemaSphere8 citations Open access
Semantic Scholar
Interim Results of the Canadian Tyrosine Kinase Inhibitor Discontinuation Trial for 2nd Attempt of Treatment Free Remission: Treatment Free Remission Accomplished By Dasatinib (TRAD)
D. Kim, I. Bence-Bruckler, D. Forrest, L. Savoie +10 more
20177 citations
Semantic Scholar
Prospective Symptom Burden Analysis in 784 Patients with Myeloproliferative Neoplasms: High Burden Correlates with Inflammatory/Genetic Biomarkers and Reduced Survival
Alisa Poullet, L. Busque, Shireen Sirhan, R. Delage +10 more
2023Blood6 citations
Semantic Scholar
Perioperative management of myeloproliferative neoplasms: A pan‐Canadian physician survey and international expert opinion
N. Szuber, P. Toliopoulos, L. Busque, Sonia Cerquozzi +10 more
2022American journal of hematology/oncology6 citations
Semantic Scholar
Single UM171 Expanded Cord Blood Transplant is Feasible, Safe, and Permits Transplantation of Better HLA Matched Cords with Very Low Transplant Related Mortality
S. Cohen, J. Roy, S. Lachance, A. Marinier +14 more
20186 citations Open access
Semantic Scholar
Interplay between hereditary and acquired factors determines the neutrophil counts in older individuals
M. Gagnon, S. Provost, Maxine Sun, S. Ayachi +5 more
2023Blood Advances5 citations Open access
Semantic Scholar
Secondary Erythrocytosis Is Phenotypically Distinct from Polycythemia Vera but Associated with Comparable Rates of Thrombosis at Diagnosis
Eliane Nguyen, N. Szuber, Michael Harnois, L. Busque +5 more
20205 citations
Semantic Scholar
Early switch to second‐line tyrosine kinase inhibitor in chronic myeloid leukemia patients failing to achieve early molecular response
Adi J. Klil-Drori, Hui Yin, L. Azoulay, M. Harnois +8 more
2017American journal of hematology/oncology5 citations Open access
Semantic Scholar
Childhood maltreatment and leukocyte telomere length in men and women with chronic illness: an evaluation of moderating and mediating influences
Alexandra Connor, L. Starnino, L. Busque, J. Tardif +4 more
2022Psychological Medicine4 citations Open access
Semantic Scholar

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