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S. Kent · SciRah

Researcher profile · Semantic Scholar

S. Kent

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S. Kent — researcher profile on SciRah

h-index: 54
Works: 218
Citations: 15K

Most-cited papers

Total chemical synthesis of proteins.
S. Kent
2009Chemical Society Reviews716 citations
Semantic Scholar
In situ neutralization in Boc-chemistry solid phase peptide synthesis. Rapid, high yield assembly of difficult sequences.
M. Schnölzer, P. Alewood, Alun Jones, D. Alewood +1 more
2009515 citations
Semantic Scholar
Photosensitivity of neurons enabled by cell-targeted gold nanoparticles
J. Carvalho-de-Souza, Jeremy S. Treger, B. Dang, S. Kent +2 more
2015Neuron346 citations Open access
Semantic Scholar
X-ray Structure of Snow Flea Antifreeze Protein Determined by Racemic Crystallization of Synthetic Protein Enantiomers
B. Pentelute, Zachary P. Gates, V. Tereshko, Jennifer L. Dashnau +3 more
2008Journal of the American Chemical Society222 citations Open access
Semantic Scholar
Racemic protein crystallography.
T. Yeates, S. Kent
2012Annual Review of Biophysics143 citations
Semantic Scholar
Chemical synthesis and X-ray structure of a heterochiral {D-protein antagonist plus vascular endothelial growth factor} protein complex by racemic crystallography
K. Mandal, M. Uppalapati, D. Ault-Riche, J. Kenney +3 more
2012Proceedings of the National Academy of Sciences of the United States of America127 citations Open access
Semantic Scholar
A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo.
M. Uppalapati, Dong-Jun Lee, K. Mandal, Hong-Yan Li +7 more
2016ACS Chemical Biology95 citations Open access
Semantic Scholar
Native Chemical Ligation at Asx-Cys, Glx-Cys: Chemical Synthesis and High Resolution X-ray Structure of ShK Toxin by Racemic Protein Crystallography
B. Dang, T. Kubota, K. Mandal, F. Bezanilla +1 more
2013Journal of the American Chemical Society85 citations Open access
Semantic Scholar
An investigation into the origin of the dramatically reduced reactivity of peptide-prolyl-thioesters in native chemical ligation.
S. Pollock, S. Kent
2011Chemical Communications85 citations
Semantic Scholar
Fully Convergent Chemical Synthesis of Ester Insulin: Determination of the High Resolution X-ray Structure by Racemic Protein Crystallography
Michal Avital-Shmilovici, K. Mandal, Zachary P. Gates, N. Phillips +2 more
2013Journal of the American Chemical Society74 citations Open access
Semantic Scholar
Weak acid-catalyzed pyrrolidone carboxylic acid formation from glutamine during solid phase peptide synthesis. Minimization by rapid coupling.
R. DiMarchi, J. Tam, S. Kent, R. B. Merrifield
2009International journal of peptide & protein research69 citations
Semantic Scholar
Convergent Chemical Synthesis of [Lysine24,38,83] Human Erythropoietin
Suhuai Liu, B. Pentelute, S. Kent
2011Angewandte Chemie68 citations Open access
Semantic Scholar
A one-pot approach to neoglycopeptides using orthogonal native chemical ligation and click chemistry.
Dong-Jun Lee, K. Mandal, P. Harris, M. Brimble +1 more
2009Organic Letters64 citations
Semantic Scholar
Design and Folding of [GluA4(OβThrB30)]Insulin (‘Ester Insulin’), a Minimal Proinsulin Surrogate Chemically Convertible to Human Insulin
Youhei Sohma, Q. Hua, J. Whittaker, M. Weiss +1 more
2010Angewandte Chemie60 citations Open access
Semantic Scholar
Total Chemical Synthesis of Biologically Active Vascular Endothelial Growth Factor
K. Mandal, S. Kent
2011Angewandte Chemie59 citations Open access
Semantic Scholar
Biomimetic Synthesis of Lispro Insulin via a Chemically Synthesized “Mini-Proinsulin” Prepared by Oxime-Forming Ligation
Youhei Sohma, S. Kent
2009Journal of the American Chemical Society56 citations Open access
Semantic Scholar
(Quasi-)racemic X-ray structures of glycosylated and non-glycosylated forms of the chemokine Ser-CCL1 prepared by total chemical synthesis.
R. Okamoto, K. Mandal, M. Sawaya, Y. Kajihara +2 more
2014Angewandte Chemie46 citations
Semantic Scholar
A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography
R. D. Bunker, K. Mandal, G. Bashiri, Jessica J. Chaston +4 more
2015Proceedings of the National Academy of Sciences of the United States of America43 citations Open access
Semantic Scholar
Through the looking glass – a new world of proteins enabled by chemical synthesis
S. Kent, Youhei Sohma, Suhuai Liu, D. Bang +2 more
2012Journal of Peptide Science42 citations
Semantic Scholar
Design, total chemical synthesis, and X-ray structure of a protein having a novel linear-loop polypeptide chain topology.
K. Mandal, B. Pentelute, D. Bang, Zachary P. Gates +2 more
2012Angewandte Chemie42 citations
Semantic Scholar
Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography.
B. Pentelute, K. Mandal, Zachary P. Gates, M. Sawaya +2 more
2010Chemical Communications41 citations
Semantic Scholar
X-ray Structure of Native Scorpion Toxin BmBKTx1 by Racemic Protein Crystallography Using Direct Methods
K. Mandal, B. Pentelute, V. Tereshko, A. Kossiakoff +1 more
2009Journal of the American Chemical Society41 citations Open access
Semantic Scholar
Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET
T. Kubota, T. Durek, B. Dang, Rocio K. Finol-Urdaneta +5 more
2017Proceedings of the National Academy of Sciences of the United States of America36 citations Open access
Semantic Scholar
Total chemical synthesis and biological activities of glycosylated and non-glycosylated forms of the chemokines CCL1 and Ser-CCL1.
R. Okamoto, K. Mandal, M. Ling, A. Luster +2 more
2014Angewandte Chemie36 citations
Semantic Scholar
Perplexing cooperative folding and stability of a low-sequence complexity, polyproline 2 protein lacking a hydrophobic core
Zachary P. Gates, Michael C. Baxa, Wookyung Yu, Joshua A. Riback +4 more
2017Proceedings of the National Academy of Sciences of the United States of America35 citations Open access
Semantic Scholar
Racemic & quasi-racemic protein crystallography enabled by chemical protein synthesis.
S. Kent
2018Current Opinion in Chemical Biology27 citations
Semantic Scholar
Bringing the science of proteins into the realm of organic chemistry: total chemical synthesis of SEP (synthetic erythropoiesis protein).
S. Kent
2013Angewandte Chemie27 citations
Semantic Scholar
Total Chemical Synthesis of Biologically Active Fluorescent Dye-Labeled Ts1 Toxin
B. Dang, T. Kubota, A. M. Correa, F. Bezanilla +1 more
2014Angewandte Chemie25 citations Open access
Semantic Scholar
Ionization state of the catalytic dyad Asp25/25’ in the HIV-1 protease: NMR studies of site-specifically 13C labelled HIV-1 protease prepared by total chemical synthesis
V. Torbeev, S. Kent
2012Organic and biomolecular chemistry25 citations Open access
Semantic Scholar
Contribution of Residue B5 to the Folding and Function of Insulin and IGF-I
Youhei Sohma, Q. Hua, Ming Liu, N. Phillips +8 more
2009Journal of Biological Chemistry25 citations Open access
Semantic Scholar
Total chemical synthesis of the enzyme sortase A(ΔN59) with full catalytic activity.
Fang-kun Deng, Liang Zhang, Ya-Ting Wang, O. Schneewind +1 more
2014Angewandte Chemie24 citations
Semantic Scholar
Rapid formal hydrolysis of peptide-αthioesters.
Zachary P. Gates, Jules Stephan, Dong-Jun Lee, S. Kent
2013Chemical Communications22 citations
Semantic Scholar
Total chemical synthesis of human proinsulin
Samuel Luisier, Michal Avital-Shmilovici, M. Weiss, S. Kent
2010Chemical Communications22 citations Open access
Semantic Scholar
Scope & Limitations of Fmoc Chemistry SPPS-Based Approaches to the Total Synthesis of Insulin Lispro via Ester Insulin
B. Dhayalan, K. Mandal, N. Rege, M. Weiss +4 more
2017Chemistry20 citations Open access
Semantic Scholar
Chemical protein synthesis
P. Alewood, M. Engelhard, S. Kent
2010Journal of Peptide Science19 citations
Semantic Scholar
Deciphering a Molecular Mechanism of Neonatal Diabetes Mellitus by the Chemical Synthesis of a Protein Diastereomer, [d-AlaB8]Human Proinsulin*
Michal Avital-Shmilovici, J. Whittaker, M. Weiss, S. Kent
2014Journal of Biological Chemistry17 citations Open access
Semantic Scholar
Inversion of Thr and Ile Side Chain Stereochemistry in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin Protein Molecule
B. Dang, R. Shen, T. Kubota, K. Mandal +3 more
2017Angewandte Chemie16 citations Open access
Semantic Scholar
Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin
B. Dang, T. Kubota, K. Mandal, A. M. Correa +2 more
2016Angewandte Chemie16 citations Open access
Semantic Scholar
Role of a salt bridge in the model protein crambin explored by chemical protein synthesis: X-ray structure of a unique protein analogue, [V15A]crambin-alpha-carboxamide.
D. Bang, V. Tereshko, A. Kossiakoff, S. Kent
2009Molecular Biosystems15 citations
Semantic Scholar
β1-subunit–induced structural rearrangements of the Ca2+- and voltage-activated K+ (BK) channel
J. P. Castillo, Jorge E. Sánchez-Rodríguez, H. C. Hyde, C. Zaelzer +7 more
2016Proceedings of the National Academy of Sciences of the United States of America14 citations Open access
Semantic Scholar
Design and Folding of [GluA4(OβThrB30)]Insulin (“Ester Insulin”): A Minimal Proinsulin Surrogate that Can Be Chemically Converted into Human Insulin.
Youhei Sohma, Q. Hua, J. Whittaker, M. Weiss +1 more
201014 citations
Semantic Scholar
Enhanced Solvation of Peptides Attached to "Solid-Phase" Resins: Straightforward Syntheses of the Elastin Sequence Pro-Gly-Val-Gly-Val-Pro-Gly-Val-Gly-Val.
B. Dang, B. Dhayalan, S. Kent
2015Organic Letters12 citations
Semantic Scholar
Chemical mechanism to account for artifactual formation of shortened peptides with free alpha-amino groups in solid phase peptide synthesis.
S. Kent, R. B. Merrifield
2009International journal of peptide & protein research12 citations
Semantic Scholar
Obviation of hydrogen fluoride in Boc chemistry solid phase peptide synthesis of peptide-αthioesters.
Zachary P. Gates, B. Dhayalan, S. Kent
2016Chemical Communications10 citations
Semantic Scholar
Total chemical synthesis of fully functional Photoactive Yellow Protein.
W. Gordon, D. Bang, W. Hoff, S. Kent
2013Bioorganic & Medicinal Chemistry9 citations
Semantic Scholar
Single-wavelength phasing strategy for quasi-racemic protein crystal diffraction data.
M. Sawaya, B. Pentelute, S. Kent, T. Yeates
2012Acta Crystallographica Section D: Biological Crystallography9 citations
Semantic Scholar
Reinvestigation of the biological activity of d-allo-ShK protein
B. Dang, S. Chhabra, M. Pennington, R. Norton +1 more
2017Journal of Biological Chemistry8 citations Open access
Semantic Scholar
Visualizing Tetrahedral Oxyanion Bound in HIV-1 Protease Using Neutrons: Implications for the Catalytic Mechanism and Drug Design
Mukesh Kumar, K. Mandal, M. Blakeley, T. Wymore +4 more
2020ACS Omega7 citations Open access
Semantic Scholar
Editorial overview: synthetic biomolecules.
S. Kent, P. Alewood
2014Current Opinion in Chemical Biology7 citations
Semantic Scholar
Synthesis of tripeptide mimetics based on dihydroquinolinone and benzoxazinone scaffolds.
A. D. de Araujo, C. Christensen, J. Buchardt, S. Kent +1 more
2011Chemistry7 citations
Semantic Scholar

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