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K. Mandal · SciRah

Researcher profile · Semantic Scholar

K. Mandal

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K. Mandal — researcher profile on SciRah

h-index: 25
Works: 106
Citations: 1,634

Most-cited papers

Chemical synthesis and X-ray structure of a heterochiral {D-protein antagonist plus vascular endothelial growth factor} protein complex by racemic crystallography
K. Mandal, M. Uppalapati, D. Ault-Riche, J. Kenney +3 more
2012Proceedings of the National Academy of Sciences of the United States of America127 citations Open access
Semantic Scholar
A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo.
M. Uppalapati, Dong-Jun Lee, K. Mandal, Hong-Yan Li +7 more
2016ACS Chemical Biology95 citations Open access
Semantic Scholar
Native Chemical Ligation at Asx-Cys, Glx-Cys: Chemical Synthesis and High Resolution X-ray Structure of ShK Toxin by Racemic Protein Crystallography
B. Dang, T. Kubota, K. Mandal, F. Bezanilla +1 more
2013Journal of the American Chemical Society85 citations Open access
Semantic Scholar
Racemic crystallography of synthetic protein enantiomers used to determine the X‐ray structure of plectasin by direct methods
K. Mandal, B. Pentelute, V. Tereshko, Vilasak Thammavongsa +3 more
2009Protein Science79 citations Open access
Semantic Scholar
Fully Convergent Chemical Synthesis of Ester Insulin: Determination of the High Resolution X-ray Structure by Racemic Protein Crystallography
Michal Avital-Shmilovici, K. Mandal, Zachary P. Gates, N. Phillips +2 more
2013Journal of the American Chemical Society74 citations Open access
Semantic Scholar
Diversity-oriented approach to biologically relevant molecular frameworks starting with beta-naphthol and using the Claisen rearrangement and olefin metathesis as key steps.
S. Kotha, K. Mandal, Arti Tiwari, S. M. Mobin
2006Chemistry71 citations
Semantic Scholar
A retrospective on the design and synthesis of novel molecules through a strategic consideration of metathesis and Suzuki-Miyaura cross-coupling.
S. Kotha, K. Mandal
2009Chemistry - An Asian Journal67 citations
Semantic Scholar
A one-pot approach to neoglycopeptides using orthogonal native chemical ligation and click chemistry.
Dong-Jun Lee, K. Mandal, P. Harris, M. Brimble +1 more
2009Organic Letters64 citations
Semantic Scholar
Total Chemical Synthesis of Biologically Active Vascular Endothelial Growth Factor
K. Mandal, S. Kent
2011Angewandte Chemie59 citations Open access
Semantic Scholar
Formation of arenes via diallylarenes : Strategic utilization of suzuki-miyaura cross-coupling, claisen rearrangement and ring-closing metathesis
S. Kotha, Vrajesh R. Shah, K. Mandal
200750 citations
Semantic Scholar
(Quasi-)racemic X-ray structures of glycosylated and non-glycosylated forms of the chemokine Ser-CCL1 prepared by total chemical synthesis.
R. Okamoto, K. Mandal, M. Sawaya, Y. Kajihara +2 more
2014Angewandte Chemie46 citations
Semantic Scholar
Determination of the X‐ray structure of the snake venom protein omwaprin by total chemical synthesis and racemic protein crystallography
James R. Banigan, K. Mandal, M. Sawaya, Vilasak Thammavongsa +4 more
2010Protein Science46 citations Open access
Semantic Scholar
A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography
R. D. Bunker, K. Mandal, G. Bashiri, Jessica J. Chaston +4 more
2015Proceedings of the National Academy of Sciences of the United States of America43 citations Open access
Semantic Scholar
Through the looking glass – a new world of proteins enabled by chemical synthesis
S. Kent, Youhei Sohma, Suhuai Liu, D. Bang +2 more
2012Journal of Peptide Science42 citations
Semantic Scholar
Design, total chemical synthesis, and X-ray structure of a protein having a novel linear-loop polypeptide chain topology.
K. Mandal, B. Pentelute, D. Bang, Zachary P. Gates +2 more
2012Angewandte Chemie42 citations
Semantic Scholar
Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography.
B. Pentelute, K. Mandal, Zachary P. Gates, M. Sawaya +2 more
2010Chemical Communications41 citations
Semantic Scholar
X-ray Structure of Native Scorpion Toxin BmBKTx1 by Racemic Protein Crystallography Using Direct Methods
K. Mandal, B. Pentelute, V. Tereshko, A. Kossiakoff +1 more
2009Journal of the American Chemical Society41 citations Open access
Semantic Scholar
Total chemical synthesis and biological activities of glycosylated and non-glycosylated forms of the chemokines CCL1 and Ser-CCL1.
R. Okamoto, K. Mandal, M. Ling, A. Luster +2 more
2014Angewandte Chemie36 citations
Semantic Scholar
Synthesis of Novel Quinone–Amino Acid Hybrids via Cross‐Enyne Metathesis and Diels–Alder Reaction as Key Steps
S. Kotha, K. Mandal, Shaibal Banerjee, S. M. Mobin
200731 citations
Semantic Scholar
New Synthetic Approach to a [1.1.6] Metapara Cyclophane Derivative via Suzuki–Miyaura Cross-Coupling and Ring-Closing Metathesis†
S. Kotha, K. Mandal, K. Arora, V. Pedireddi
200531 citations
Semantic Scholar
Dynamics of "flap" structures in three HIV-1 protease/inhibitor complexes probed by total chemical synthesis and pulse-EPR spectroscopy.
V. Torbeev, H. Raghuraman, K. Mandal, Sanjib Senapati +2 more
2009Journal of the American Chemical Society30 citations
Semantic Scholar
Suzuki–Miyaura Cross‐Coupling and Ring‐Closing Metathesis: A Strategic Combination for the Synthesis of Cyclophane Derivatives
S. Kotha, K. Mandal
200625 citations
Semantic Scholar
Repurposing an Antiviral Drug against SARS‐CoV‐2 Main Protease
Arighna Sarkar, K. Mandal
2021Angewandte Chemie21 citations Open access
Semantic Scholar
Scope & Limitations of Fmoc Chemistry SPPS-Based Approaches to the Total Synthesis of Insulin Lispro via Ester Insulin
B. Dhayalan, K. Mandal, N. Rege, M. Weiss +4 more
2017Chemistry20 citations Open access
Semantic Scholar
Efficient Total Chemical Synthesis of 13C=18O Isotopomers of Human Insulin for Isotope-Edited FTIR
B. Dhayalan, A. Fitzpatrick, K. Mandal, J. Whittaker +3 more
2016ChemBioChem19 citations Open access
Semantic Scholar
Inversion of Thr and Ile Side Chain Stereochemistry in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin Protein Molecule
B. Dang, R. Shen, T. Kubota, K. Mandal +3 more
2017Angewandte Chemie16 citations Open access
Semantic Scholar
Crystallization of Enantiomerically Pure Proteins from Quasi‐Racemic Mixtures: Structure Determination by X‐Ray Diffraction of Isotope‐Labeled Ester Insulin and Human Insulin
K. Mandal, B. Dhayalan, Michal Avital-Shmilovici, A. Tokmakoff +1 more
2016ChemBioChem16 citations
Semantic Scholar
Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin
B. Dang, T. Kubota, K. Mandal, A. M. Correa +2 more
2016Angewandte Chemie16 citations Open access
Semantic Scholar
Crystal structure of chemically synthesized HIV-1 protease and a ketomethylene isostere inhibitor based on the p2/NC cleavage site.
V. Torbeev, K. Mandal, V. Terechko, S. Kent
2008Bioorganic & Medicinal Chemistry Letters16 citations
Semantic Scholar
Efficient Chemical Protein Synthesis using Fmoc-Masked N-Terminal Cysteine in Peptide Thioester Segments
A. Kar, Jamsad Mannuthodikayil, S. Singh, Anamika Biswas +3 more
2020Angewandte Chemie15 citations Open access
Semantic Scholar
Benzimidazolinone-Free Peptide o-Aminoanilides for Chemical Protein Synthesis.
Jamsad Mannuthodikayil, S. Singh, Anamika Biswas, A. Kar +4 more
2019Organic Letters15 citations
Semantic Scholar
Steering diffusion selectivity of chemical isomers within aligned nanochannels of metal-organic framework thin film
Tanmay Maity, Susmita Sarkar, Susmita Kundu, Suvendu Panda +6 more
2024Nature Communications12 citations Open access
Semantic Scholar
Rational design of protein-specific folding modifiers
Anirban Das, Anju Yadav, Mona Gupta, R. Purushotham +9 more
2020bioRxiv9 citations Open access
Semantic Scholar
Metathesis of a novel dienediyne system: A unique example involving the usage of in situ generated ethylene as cross-enyne metathesis partner
S. Kotha, K. Mandal
20078 citations
Semantic Scholar
Tetra-benzimidazoles flanking divinyl-phenothiazine: AIEgens as aza-Michael acceptors in concentration-tuned responses to biogenic amine vapors.
Sameer Singh, K. Mandal, M. Chakravarty
2024Chemical Communications7 citations Open access
Semantic Scholar
Visualizing Tetrahedral Oxyanion Bound in HIV-1 Protease Using Neutrons: Implications for the Catalytic Mechanism and Drug Design
Mukesh Kumar, K. Mandal, M. Blakeley, T. Wymore +4 more
2020ACS Omega7 citations Open access
Semantic Scholar
Synthesis and comparative properties of two amide‐generating resin linkers for use in solid phase peptide synthesis
Fang-kun Deng, K. Mandal, Samuel Luisier, S. Kent
2010Journal of Peptide Science6 citations
Semantic Scholar
Activation of Mas and pGCA receptor pathways protects renal epithelial cell damage against oxidative-stress-induced injury.
Trupti Ghatage, Sameer Singh, K. Mandal, Kirtikumar B. Jadhav +1 more
2023Peptides5 citations
Semantic Scholar
Rational Design of Protein-Specific Folding Modifiers.
Anirban Das, Anju Yadav, Mona Gupta, P. R. +10 more
2021Journal of the American Chemical Society5 citations Open access
Semantic Scholar
A Chimeric Peptide Inhibits Red Blood Cell Invasion by Plasmodium falciparum with Hundredfold Increased Efficacy
Jamsad Mannuthodikayil, Suman Sinha, S. Singh, Anamika Biswas +6 more
2021bioRxiv5 citations Open access
Semantic Scholar
Neoglycoprotein Synthesis Using the Copper‐Catalyzed Azide–Alkyne Click Reaction and Native Chemical Ligation
J. Wojnar, Dong-Jun Lee, C. Evans, K. Mandal +2 more
20135 citations
Semantic Scholar
Reprint of "Crystal structure of chemically synthesized HIV-1 protease and a ketomethylene isostere inhibitor based on the p2/NC cleavage site" [Bioorg. Med. Chem. Lett. 18 (2008) 4554-4557].
V. Torbeev, K. Mandal, V. Terechko, S. Kent
2008Bioorganic & Medicinal Chemistry Letters5 citations
Semantic Scholar
Co-activation of Mas and pGCA receptors suppresses endothelin-1-induced endothelial dysfunction via nitric oxide/cGMP system.
Trupti Ghatage, Sameer Singh, K. Mandal, A. Dhar
2024Biochimica et Biophysica Acta - Molecular Basis of Disease4 citations Open access
Semantic Scholar
MasR and pGCA receptor activation protects primary vascular smooth muscle cells and endothelial cells against oxidative stress via inhibition of intracellular calcium
Trupti Ghatage, Sameer Singh, K. Mandal, A. Dhar
2023Journal of Cellular Biochemistry4 citations Open access
Semantic Scholar
Efficient refolding and functional characterization of PfAMA1(DI+DII) expressed in E. coli
Anamika Biswas, S. Raran-Kurussi, Akash Narayan, A. Kar +3 more
2021Biochemistry and Biophysics Reports4 citations Open access
Semantic Scholar
Protein denaturation induced electrocatalytic hydrogen evolution
Jamsad Mannuthodikayil, Sreekanth Narayanaru, P. Thakur, Sumit Bawari +2 more
20204 citations
Semantic Scholar
Access to Diverse Glutamic Acid Dendrons and a Janus Peptide Dendrimer Using an Atypical Solid Phase Synthesis.
Sameer Singh, K. Mandal, M. Chakravarty
2024Journal of Organic Chemistry3 citations
Semantic Scholar
Expression, purification, and refolding of an optimized SARS-CoV-2 receptor binding domain in E. coli.
Anamika Biswas, Arighna Sarkar, S. Raran-Kurussi, K. Mandal
2025Plasmid2 citations
Semantic Scholar
An Elegant Method of One‐Pot Ligation‐Desulfurization for High‐Yielding Chemical Protein Synthesis
Vishal Malik, Abhisek Kar, Anandh Muthiah Venkatachalam, K. Mandal
2025Advancement of science2 citations Open access
Semantic Scholar
Rational engineering of an antimalarial peptide with enhanced proteolytic stability and preserved parasite invasion inhibitory activity
Abhisek Kar, Akash Narayan, Vishal Malik, K. Mandal
2024RSC Chemical Biology2 citations Open access
Semantic Scholar

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