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D. Laface · SciRah

Researcher profile · Semantic Scholar

D. Laface

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D. Laface — researcher profile on SciRah

h-index: 30
Works: 67
Citations: 9,733

Most-cited papers

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl
S. Martin, Chris P. M. Reutelingsperger, A. Mcgahon, James A. Rader +3 more
1995Journal of Experimental Medicine3,056 citations Open access
Semantic Scholar
Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas
T. Brunner, R. Mogil, D. Laface, N. Yoo +7 more
1995Nature1,436 citations
Semantic Scholar
IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4−CD8− entheseal resident T cells
J. Sherlock, B. Joyce-Shaikh, S. Turner, Cheng-chi Chao +12 more
2012Nature Medicine1,071 citations
Semantic Scholar
MyD88-dependent expansion of an immature GR-1+CD11b+ population induces T cell suppression and Th2 polarization in sepsis
Matthew J. Delano, Philip O. Scumpia, J. Weinstein, Dominique P. Coco +18 more
2007Journal of Experimental Medicine707 citations Open access
Semantic Scholar
IL-10 elicits IFNγ-dependent tumor immune surveillance.
J. Mumm, J. Emmerich, Xue-Qing Zhang, I. Chan +27 more
2011Cancer Cell385 citations Open access
Semantic Scholar
A Paradoxical Role for Myeloid-Derived Suppressor Cells in Sepsis and Trauma
A. Cuenca, Matthew J. Delano, K. Kelly-Scumpia, Claudia Moreno +5 more
2011Molecular Medicine362 citations Open access
Semantic Scholar
Interleukin-17A upregulates receptor activator of NF-κB on osteoclast precursors
I. Adamopoulos, Cheng-chi Chao, R. Geissler, D. Laface +4 more
2010Arthritis Research & Therapy311 citations Open access
Semantic Scholar
IL-10 directly activates and expands tumor-resident CD8(+) T cells without de novo infiltration from secondary lymphoid organs.
J. Emmerich, J. Mumm, I. Chan, D. Laface +4 more
2012Cancer Research270 citations
Semantic Scholar
IL-23 Is Critical for Induction of Arthritis, Osteoclast Formation, and Maintenance of Bone Mass
I. Adamopoulos, Marlowe S. Tessmer, Cheng-chi Chao, Sarvesh Adda +8 more
2011Journal of Immunology209 citations Open access
Semantic Scholar
Neutrophil Mobilization from the Bone Marrow During Polymicrobial Sepsis Is Dependent On CXCL12 Signaling
Matthew J. Delano, K. Kelly-Scumpia, Terri C. Thayer, R. Winfield +13 more
2011Journal of Immunology145 citations Open access
Semantic Scholar
Interleukin-23 is sufficient to induce rapid de novo gut tumorigenesis, independent of carcinogens, through activation of innate lymphoid cells
I. Chan, R. Jain, Marlowe S. Tessmer, Dan Gorman +18 more
2013Mucosal Immunology137 citations Open access
Semantic Scholar
Targeted adenovirus-induced expression of IL-10 decreases thymic apoptosis and improves survival in murine sepsis
C. Oberholzer, A. Oberholzer, F. R. Bahjat, R. Minter +6 more
2001Proceedings of the National Academy of Sciences of the United States of America130 citations Open access
Semantic Scholar
Activation-induced cell death in murine T cell hybridomas. Differential regulation of Fas (CD95) versus Fas ligand expression by cyclosporin A and FK506.
Thomas Brunner, Nam Jin Yoo, D. Laface, Carl F. Ware +1 more
1996International Immunology124 citations
Semantic Scholar
Central Nervous System Expression of IL-10 Inhibits Autoimmune Encephalomyelitis1
D. Cua, B. Hutchins, D. Laface, S. Stohlman +1 more
2001Journal of Immunology108 citations Open access
Semantic Scholar
Selecting T cell receptors with high affinity for self-MHC by decreasing the contribution of CD8.
Linda A. Sherman, Sabine Hesse, M. Irwin, D. Laface +1 more
1992Science106 citations
Semantic Scholar
Reciprocal Allogeneic Bone Marrow Transplantation Between NOD Mice and Diabetes-Nonsusceptible Mice Associated With Transfer and Prevention of Autoimmune Diabetes
D. Laface, A. Peck
1989Diabetes95 citations
Semantic Scholar
Impact of Human Neutralizing Antibodies on Antitumor Efficacy of an Oncolytic Adenovirus in a Murine Model
V. Tsai, Duane E. Johnson, A. Rahman, Shu Wen +7 more
2004Clinical Cancer Research89 citations Open access
Semantic Scholar
Central Nervous System Expression of IL-10 Inhibits Autoimmune Encephalomyelitis
D. Cua, B. Hutchins, D. Laface, S. Stohlman +1 more
200082 citations
Semantic Scholar
TNF-α Receptor Signaling and IL-10 Gene Therapy Regulate the Innate and Humoral Immune Responses to Recombinant Adenovirus in the Lung1
R. Minter, J. Rectenwald, K. Fukuzuka, Cynthia L. Tannahill +7 more
2000Journal of Immunology79 citations Open access
Semantic Scholar
IL-10 overexpression differentially affects cartilage matrix gene expression in response to TNF-alpha in human articular chondrocytes in vitro.
R. D. Müller, T. John, B. Kohl, A. Oberholzer +10 more
2008Cytokine72 citations
Semantic Scholar
Novel Role for Tumor-Induced Expansion of Myeloid Derived Cells in Cancer Cachexia
Alex G. Cuenca, A. Cuenca, R. Winfield, Dallas N. Joiner +10 more
2014Journal of Immunology68 citations Open access
Semantic Scholar
Increased Survival in Sepsis by In Vivo Adenovirus-Induced Expression of IL-10 in Dendritic Cells1
A. Oberholzer, C. Oberholzer, K. Bahjat, R. Ungaro +9 more
2002Journal of Immunology68 citations Open access
Semantic Scholar
Gene transfer into hematopoietic progenitor cells mediated by an adeno-associated virus vector.
D. Laface, P. Hermonat, E. K. Wakeland, Ammon B. Peck
1988Virology63 citations
Semantic Scholar
Adenoviral Delivery of Human and Viral IL-10 in Murine Sepsis1
R. Minter, M. Ferry, Michelle Murday, Cynthia L. Tannahill +9 more
2001Journal of Immunology48 citations Open access
Semantic Scholar
Specific depletion of human anti-adenovirus antibodies facilitates transduction in an in vivo model for systemic gene therapy.
A. Rahman, V. Tsai, A. Goudreau, Jeremy Shinoda +6 more
2001Molecular Therapy48 citations Open access
Semantic Scholar
Evaluation of endostatin antiangiogenesis gene therapy in vitro and in vivo
Xiaomei Jin, R. Bookstein, K. Wills, Jenny B. Avanzini +5 more
2001Cancer Gene Therapy45 citations
Semantic Scholar
Effective Anti-tumor Response by TIGIT Blockade Associated With FcγR Engagement and Myeloid Cell Activation
Jin-Hwan Han, Mingmei Cai, Jeff Grein, S. Perera +8 more
2020Frontiers in Immunology43 citations Open access
Semantic Scholar
p34cdc2 and apoptosis.
S. J. Martin, A. Mcgahon, W. Nishioka, D. Laface +4 more
1995Science38 citations
Semantic Scholar
Extended lung expression and increased tissue localization of viral IL-10 with adenoviral gene therapy.
R. Minter, M. Ferry, John E. Rectenwald, F. R. Bahjat +9 more
2001Proceedings of the National Academy of Sciences of the United States of America31 citations Open access
Semantic Scholar
Myeloid Derived Suppressor Cells in Cancer Cachexia Syndrome: A New Explanation for an Old Problem
R. Winfield, Matthew J. Delano, K. Pande, Philip O. Scumpia +2 more
2008JPEN - Journal of Parenteral and Enteral Nutrition30 citations Open access
Semantic Scholar
Cancer-induced expansion and activation of CD11b+ Gr-1+ cells predispose mice to adenoviral-triggered anaphylactoid-type reactions.
K. Pande, Roanna M. Ueda, T. Machemer, Manjiri Sathe +9 more
2009Molecular Therapy28 citations Open access
Semantic Scholar
Antitumor efficacy of combined CTLA4/PD-1 blockade without intestinal inflammation is achieved by elimination of FcγR interactions
David Bauché, S. Mauze, Christina M. Kochel, Jeff Grein +10 more
2020Journal for ImmunoTherapy of Cancer23 citations Open access
Semantic Scholar
Endogenous IL-10 Regulates Sepsis-induced Thymic Apoptosis and Improves Survival in Septic IL-10 Null Mice
S. Tschoeke, C. Oberholzer, D. Laface, B. Hutchins +2 more
2008Scandinavian Journal of Immunology20 citations Open access
Semantic Scholar
FUNCTIONAL MODIFICATION OF DENDRITIC CELLS WITH RECOMBINANT ADENOVIRUS ENCODING INTERLEUKIN 10 FOR THE TREATMENT OF SEPSIS
A. Oberholzer, C. Oberholzer, P. Efron, Philip O. Scumpia +11 more
2005Shock19 citations
Semantic Scholar
C17 Prevents Inflammatory Arthritis and Associated Joint Destruction in Mice
C. Chao, B. Joyce-Shaikh, J. Grein, Mehrdad Moshrefi +7 more
2011PLoS ONE18 citations Open access
Semantic Scholar
Adenovirus delivery provides extended interferon-α exposure and augments treatment of metastatic carcinoma
E. Brin, I. Atencio, B. K. Helmich, D. Maneval +1 more
2006Cancer Gene Therapy17 citations Open access
Semantic Scholar
Characterization of hemodynamic events following intravascular infusion of recombinant adenovirus reveals possible solutions for mitigating cardiovascular responses.
T. Machemer, H. Engler, V. Tsai, Seoju Lee +14 more
2005Molecular Therapy17 citations Open access
Semantic Scholar
Rapid detection and quantification of apolipoprotein L1 genetic variants and total levels in plasma by ultra-performance liquid chromatography/tandem mass spectrometry.
Hai-Hong Zhou, M. Hoek, Pang Yi, Rory J. Rohm +17 more
2013Rapid Communications in Mass Spectrometry15 citations
Semantic Scholar
Recombinant adenovirus-transduced human dendritic cells engineered to secrete interleukin-10 (IL-10) suppress Th1-type responses while selectively activating IL-10-producing CD4+ T cells.
D. Réa, D. Laface, B. Hutchins, K. Kwappenberg +3 more
2004Human Immunology14 citations
Semantic Scholar
Interleukin-10 fails to modulate low shear stress-induced neointimal hyperplasia.
J. Rectenwald, R. Minter, L. Moldawer, Z. Abouhamze +5 more
2002Journal of Surgical Research14 citations
Semantic Scholar
Influence of recombinant adenovirus on liver injury in endotoxicosis and its modulation by IL-10 expression.
C. Oberholzer, A. Oberholzer, S. Tschoeke, R. Minter +4 more
2004Journal of Endotoxin Research12 citations
Semantic Scholar
In vivo anti-tumor efficacy of afucosylated anti-CS1 monoclonal antibody produced in glycoengineered Pichia pastoris.
S. Gomathinayagam, D. Laface, N. R. Houston-Cummings, R. Mangadu +6 more
2015Journal of Biotechnology11 citations
Semantic Scholar
Dose-dependent improvements in outcome with adenoviral expression of interleukin-10 in a murine model of multisystem organ failure
P. McAuliffe, M. Murday, P. Efron, Philip O. Scumpia +6 more
2006Gene Therapy11 citations Open access
Semantic Scholar
Ex vivo purging by adenoviral p53 gene therapy does not affect NOD-SCID repopulating activity of human CD34+ cells
M. Hirai, D. Laface, S. Robinson, Linda S. Kelsey +13 more
2001Cancer Gene Therapy10 citations
Semantic Scholar
Transcription of retinoic acid receptor genes in transgenic mice increases CD8 T-cell subset
J. Pohl, D. Laface, J. Sands
1993Molecular Biology Reports10 citations
Semantic Scholar
Adenoviral transduction is more efficient in alginate-derived chondrocytes than in monolayer chondrocytes
Andreas Oberholzer, Thilo John, B. Kohl, T. Gust +6 more
2007Cell and Tissue Research9 citations
Semantic Scholar
Meeting report: regulatory myeloid cells.
D. Laface, J. Talmadge
2011International Immunopharmacology7 citations
Semantic Scholar
In Vivo Transduction of Thymic Dendritic Cells with Adenovirus and Its Potential Use in Acute Inflammatory Diseases
C. Oberholzer, S. Tschoeke, Keith S. Bahjat, D. Laface +4 more
2005Scandinavian Journal of Immunology7 citations
Semantic Scholar
Corrigendum: Effective Anti-tumor Response by TIGIT Blockade Associated With FcγR Engagement and Myeloid Cell Activation
Jin-Hwan Han, Mingmei Cai, Jeff Grein, S. Perera +8 more
2020Frontiers in Immunology5 citations Open access
Semantic Scholar
Cartilage-Specific Matrix and Integrin Expression in Three-Dimensional Articular Chondrocyte Cultures Overexpressing Human Interleukin-10
R. D. Müller, T. John, B. Kohl, A. Feldner +6 more
20085 citations Open access
Semantic Scholar

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