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R. Turncliff · SciRah

Researcher profile · Semantic Scholar

R. Turncliff

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R. Turncliff — researcher profile on SciRah

h-index: 17
Works: 34
Citations: 1,266

Most-cited papers

Pharmacokinetics of 5 (and 6)-Carboxy-2′,7′-Dichlorofluorescein and Its Diacetate Promoiety in the Liver
M. Zamek-Gliszczynski, Hao Xiong, Nita J. Patel, R. Turncliff +2 more
2003Journal of Pharmacology and Experimental Therapeutics180 citations
Semantic Scholar
Evaluation of Opioid Modulation in Major Depressive Disorder
E. Ehrich, R. Turncliff, Yang-Chun Du, Richard A Leigh-Pemberton +3 more
2014Neuropsychopharmacology163 citations Open access
Semantic Scholar
P-glycoprotein Expression, Localization, and Function in Sandwich-Cultured Primary Rat and Human Hepatocytes: Relevance to the Hepatobiliary Disposition of a Model Opioid Peptide
Keith A. Hoffmaster, R. Turncliff, E. LeCluyse, R. B. Kim +2 more
2004Pharmaceutical Research157 citations
Semantic Scholar
Single- and multiple-dose pharmacokinetics of long-acting injectable naltrexone.
J. Dunbar, R. Turncliff, Q. Dong, B. Silverman +2 more
2006Alcoholism: Clinical and Experimental Research120 citations
Semantic Scholar
P-glycoprotein-mediated in vitro biliary excretion in sandwich-cultured rat hepatocytes.
P. Annaert, R. Turncliff, Catherine Booth, D. Thakker +1 more
2001Drug Metabolism And Disposition96 citations
Semantic Scholar
Single- and multiple-dose pharmacokinetics of ziprasidone in healthy young and elderly volunteers.
K. Wilner, T. Tensfeldt, B. Baris, T. Smolarek +3 more
2000British Journal of Clinical Pharmacology67 citations Open access
Semantic Scholar
Effect of dexamethasone treatment on the expression and function of transport proteins in sandwich-cultured rat hepatocytes.
R. Turncliff, P. Meier, K. Brouwer
2004Drug Metabolism And Disposition61 citations
Semantic Scholar
Effect of culture conditions on the expression and function of Bsep, Mrp2, and Mdr1a/b in sandwich-cultured rat hepatocytes.
R. Turncliff, Xianbin Tian, K. Brouwer
2006Biochemical Pharmacology52 citations
Semantic Scholar
The pharmacokinetics of ziprasidone in subjects with normal and impaired renal function.
F. Aweeka, D. Jayesekara, M. Horton, S. Swan +6 more
2000British Journal of Clinical Pharmacology48 citations Open access
Semantic Scholar
Use of Remifentanil in a Novel Clinical Paradigm to Characterize Onset and Duration of Opioid Blockade by Samidorphan, a Potent μ-Receptor Antagonist
M. Shram, B. Silverman, E. Ehrich, E. Sellers +1 more
2015Journal of Clinical Psychopharmacology46 citations Open access
Semantic Scholar
Relative bioavailability and safety of aripiprazole lauroxil, a novel once-monthly, long-acting injectable atypical antipsychotic, following deltoid and gluteal administration in adult subjects with schizophrenia.
R. Turncliff, M. Hard, Yang-Chun Du, R. Risinger +1 more
2014Schizophrenia Research43 citations
Semantic Scholar
Single- and multiple-dose pharmacokinetics of samidorphan, a novel opioid antagonist, in healthy volunteers.
R. Turncliff, Lauren DiPetrillo, B. Silverman, E. Ehrich
2015Clinical Therapeutics36 citations
Semantic Scholar
Hepatobiliary Disposition of a Drug/Metabolite Pair: Comprehensive Pharmacokinetic Modeling in Sandwich-Cultured Rat Hepatocytes
R. Turncliff, Keith A. Hoffmaster, J. C. Kalvass, G. M. Pollack +1 more
2006Journal of Pharmacology and Experimental Therapeutics34 citations
Semantic Scholar
Pharmacokinetics of Long‐Acting Naltrexone in Subjects With Mild to Moderate Hepatic Impairment
R. Turncliff, Joi Dunbar, Q. Dong, B. Silverman +3 more
2005Journal of clinical pharmacology33 citations
Semantic Scholar
Population pharmacokinetics of extended-release injectable naltrexone (XR-NTX) in patients with alcohol dependence.
J. Dunbar, R. Turncliff, S. Hayes, C. Farrell
2007Journal of Studies on Alcohol and Drugs29 citations
Semantic Scholar
Aripiprazole Lauroxil
M. Hard, Richard J. Mills, B. Sadler, R. Turncliff +1 more
2017Journal of Clinical Psychopharmacology24 citations Open access
Semantic Scholar
Exceptionally high decarboxylation rate of a primary aliphatic acyloxy radical determined by radical product yield analysis and quantitative 1H‐CIDNP spectroscopy
Alicia M Fraind, R. Turncliff, T. Fox, Justin Sodano +1 more
201119 citations
Semantic Scholar
PRECLINICAL STUDY: Route of administration affects the ability of naltrexone to reduce amphetamine‐potentiated brain stimulation reward in rats
M. Todtenkopf, Krystal S. O'Neill, K. Kriksciukaite, R. Turncliff +3 more
2009Addiction Biology16 citations
Semantic Scholar
Effects of oral loperamide on efficacy of naltrexone, baclofen and AM-251 in blocking ethanol self-administration in rats.
R. Dean, D. Eyerman, M. Todtenkopf, R. Turncliff +2 more
2012Pharmacology, Biochemistry and Behavior15 citations
Semantic Scholar
P.2.090 The pharmacokinetics of ziprasidone in subjects with normal and impaired hepatic function
G. Everson, K. Lasseter, K. E. Anderson, L. A. Bauer +6 more
1997European Neuropsychopharmacology13 citations
Semantic Scholar
ALKS 27 (Trospium Inhalation Powder) Improves Lung Function Following Single Administration In Subjects With COPD
Lauren E. Oleson, R. Turncliff, B. Silverman, C. Fogarty +1 more
2010Asian Test Symposium7 citations
Semantic Scholar
P.3.c.024 ALKS 9070, a novel once monthly prodrug of aripiprazole, achieves therapeutic levels and is well-tolerated in adults with schizophrenia
R. Turncliff, E. Potocka, L. Corey, A. Lowy +3 more
20123 citations
Semantic Scholar
ALKS 37, A Novel, Peripherally-Restricted Opioid Receptor Antagonist, Demonstrates Efficacy in the Treatment of Opioid-Induced Bowel Dysfunction.
Lauren DiPetrillo, Richard A Leigh-Pemberton, A. Memişoğlu, R. Turncliff +3 more
20113 citations Open access
Semantic Scholar
A phase 3, single arm, open-label study evaluating ovarian suppression following 3-month leuprolide acetate for injectable suspension in combination with endocrine therapy in premenopausal subjects with HR+, HER2-negative breast cancer (OVELIA).
R. Tooker, E. Hamilton, Kerlin Lynch, S. Atkinson +1 more
2022Journal of Clinical Oncology1 citations
Semantic Scholar
Single and multiple dose pharmacokinetics of long‐acting injectable naltrexone
R. Turncliff, Joi Dunbar, Q. Dong, J. Oliva +2 more
20051 citations
Semantic Scholar
P-glycoprotein Expression, Localization, and Function in Sandwich-Cultured Primary Rat and Human Hepatocytes: Relevance to the
Keith A. Hoffmaster, R. Turncliff, E. LeCluyse, R. Kim +2 more
20041 citations
Semantic Scholar
Multicenter Bioavailability Study of Long-Acting Paliperidone in Patients With Schizophrenia or Schizoaffective Disorder
Thalita Martins da Silva, Débora Renz Barreto Vianna, Jessica Meulman, R. Turncliff +2 more
2025Journal of Clinical Psychopharmacology0 citations Open access
Semantic Scholar
Abstract OT3-04-01: A Phase 3 study evaluating ovarian suppression following three-month leuprolide acetate in combination with endocrine therapy in premenopausal subjects with HR+, HER2-negative breast cancer (OVELIA)
R. Turncliff, E. Hamilton, Kerlin Lynch, S. Atkinson
2023Cancer Research0 citations
Semantic Scholar
Predicting screen failure rates of human abuse potential studies
L. Webster, R. Ashwin, E. Hansen, R. Turncliff +1 more
20170 citations
Semantic Scholar
Modulation of buprenorphine partial agonism by the opioid antagonist samidorphan: A mechanistic PK/PD model
R. Turncliff, W.-I. Li
20150 citations
Semantic Scholar
A mechanistic Pk/Pd model of buprenorphine
W.-I. Li, R. Turncliff
20140 citations
Semantic Scholar
JPET #102616 HEPATOBILIARY DISPOSITION OF A DRUG/METABOLITE PAIR: COMPREHENSIVE PHARMACOKINETIC MODELING IN SANDWICH- CULTURED RAT HEPATOCYTES
R. Turncliff, Keith A. Hoffmaster, J. C. Kalvass, G. M. Pollack +1 more
20060 citations
Semantic Scholar
PI‐82
S. Hayes, C. Farrell, Joi Dunbar, R. Turncliff
20060 citations
Semantic Scholar
Steady-state pharmacokinetics of ziprasidone in healthy elderly and young volunteers
T. Tensfeldt, K. Wilner, B. Baris, T. Smolarek +3 more
19970 citations
Semantic Scholar

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