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R. Lapidus · SciRah

Researcher profile · Semantic Scholar

R. Lapidus

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R. Lapidus — researcher profile on SciRah

h-index: 33
Works: 169
Citations: 6,397

Most-cited papers

Extracellular vesicle PD-L1 dynamics predict durable response to immune-checkpoint inhibitors and survival in patients with non-small cell lung cancer
D. de Miguel-Pérez, A. Russo, O. Arrieta, M. Ak +21 more
2022Journal of experimental & clinical cancer research : CR107 citations Open access
Semantic Scholar
Gamma Delta T Cell Therapy for Cancer: It Is Good to be Local
C. Pauza, M. Liou, T. Lahusen, Lingzhi Xiao +3 more
2018Frontiers in Immunology89 citations Open access
Semantic Scholar
DNA methyltransferase inhibitors induce a BRCAness phenotype that sensitizes NSCLC to PARP inhibitor and ionizing radiation
R. Abbotts, M. Topper, C. Biondi, D. Fontaine +10 more
2019Proceedings of the National Academy of Sciences of the United States of America82 citations Open access
Semantic Scholar
Fatty Acid Synthase induced S6Kinase facilitates USP11-eIF4B complex formation for sustained oncogenic translation in DLBCL
Bandish Kapadia, N. Nanaji, Kavita Bhalla, B. Bhandary +4 more
2018Nature Communications81 citations Open access
Semantic Scholar
Liquid biopsy tracking of lung tumor evolutions over time
A. Russo, D. de Miguel Pérez, M. Gunasekaran, K. Scilla +6 more
2019Expert Review of Molecular Diagnostics57 citations
Semantic Scholar
Asparaginase Erwinia chrysanthemi effectively depletes plasma glutamine in adult patients with relapsed/refractory acute myeloid leukemia
A. Emadi, Jennie Y. Law, E. Strovel, R. Lapidus +17 more
2017Cancer Chemotherapy and Pharmacology45 citations
Semantic Scholar
Baseline extracellular vesicle TGF‐β is a predictive biomarker for response to immune checkpoint inhibitors and survival in non–small cell lung cancer
D. de Miguel-Pérez, A. Russo, M. Gunasekaran, F. Buemi +15 more
2022Cancer41 citations Open access
Semantic Scholar
Phase I clinical trial of DNA methyltransferase inhibitor decitabine and PARP inhibitor talazoparib combination therapy in relapsed/refractory acute myeloid leukemia
M. Baer, A. A. Kogan, S. Bentzen, Tian Mi +8 more
2022Clinical Cancer Research41 citations Open access
Semantic Scholar
Concurrent inhibition of Pim and FLT3 kinases enhances apoptosis of FLT3-ITD acute myeloid leukemia cells through increased Mcl-1 proteasomal degradation
Shivani Kapoor, K. Natarajan, Patrick R. Baldwin, Kshama A. Doshi +10 more
2017Clinical Cancer Research41 citations Open access
Semantic Scholar
Pharmacologic induction of innate immune signaling directly drives homologous recombination deficiency
L. McLaughlin, Lora Stojanovic, A. A. Kogan, Julia L Rutherford +8 more
2020Proceedings of the National Academy of Sciences of the United States of America34 citations Open access
Semantic Scholar
Regulation of cisplatin-resistant head and neck squamous cell carcinoma by the SRC/ETS-1 signaling pathway
Zejia Yang, Jipei Liao, Brandon A. Carter-Cooper, R. Lapidus +2 more
2019BMC Cancer33 citations Open access
Semantic Scholar
Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity
M. Kim, Ramkishore Gernapudi, E. Choi, R. Lapidus +1 more
2017OncoTarget33 citations Open access
Semantic Scholar
Pulsed focused ultrasound lowers interstitial fluid pressure and increases nanoparticle delivery and penetration in head and neck squamous cell carcinoma xenograft tumors
A. Mohammadabadi, Ruby N. Huynh, A. Wadajkar, R. Lapidus +3 more
2020Physics in Medicine and Biology32 citations Open access
Semantic Scholar
Venetoclax and pegcrisantaspase for complex karyotype acute myeloid leukemia
A. Emadi, Bandish Kapadia, D. Bollino, B. Bhandary +16 more
2020Leukemia31 citations Open access
Semantic Scholar
Potently inhibiting cancer cell migration with novel 3H-pyrazolo[4,3-f]quinoline boronic acid ROCK inhibitors.
Neetu Dayal, Clinton G Mikek, Delmis E. Hernandez, George A. Naclerio +4 more
2019European journal of medicinal chemistry27 citations Open access
Semantic Scholar
PP2A-activating drugs enhance FLT3 inhibitor efficacy through AKT inhibition-dependent GSK-3β-mediated c-Myc and Pim-1 proteasomal degradation
Mario Scarpa, Prerna Singh, Christopher Bailey, Jonelle K Lee +8 more
2021Molecular Cancer Therapeutics26 citations Open access
Semantic Scholar
Upregulation of RASSF1A in Colon Cancer by Suppression of Angiogenesis Signaling and Akt Activation
T. Blanchard, R. Lapidus, Vivekjyoti Banerjee, Andrea C. Bafford +3 more
2018Cellular Physiology and Biochemistry25 citations Open access
Semantic Scholar
The Novel Mnk1/2 Degrader and Apoptosis Inducer VNLG-152 Potently Inhibits TNBC Tumor Growth and Metastasis
S. Ramalingam, Vidya P Ramamurthy, L. Gediya, Francis N. Murigi +8 more
2019Cancers24 citations Open access
Semantic Scholar
Synthesis, anticancer activity, and SAR analyses of compounds containing the 5:7-fused 4,6,8-triaminoimidazo[4,5-e][1,3]diazepine ring system.
M. Xie, R. Lapidus, M. Sadowska, M. Edelman +1 more
2016Bioorganic & Medicinal Chemistry23 citations
Semantic Scholar
Alkyne-substituted diminazene as G-quadruplex binders with anticancer activities.
Chang-Hao Wang, Brandon A. Carter-Cooper, Yixuan Du, Jie Zhou +8 more
2016European journal of medicinal chemistry22 citations Open access
Semantic Scholar
Antileukemic efficacy of a potent artemisinin combined with sorafenib and venetoclax.
Blake S. Moses, Samantha McCullough, J. M. Fox, Bryan T. Mott +8 more
2021Blood Advances21 citations Open access
Semantic Scholar
Co-targeting EGFR and IKKβ/NF-κB signalling pathways in head and neck squamous cell carcinoma: a potential novel therapy for head and neck squamous cell cancer
Zhipeng Li, Jipei Liao, Zejia Yang, E. Choi +4 more
2018British Journal of Cancer20 citations Open access
Semantic Scholar
Equipotent doses of daunorubicin and idarubicin for AML: a meta-analysis of clinical trials versus in vitro estimation.
Sunil Adige, R. Lapidus, Brandon A. Carter-Cooper, A. Duffy +7 more
2019Cancer Chemotherapy and Pharmacology18 citations Open access
Semantic Scholar
Dual FLT3/TOPK inhibitor with activity against FLT3-ITD secondary mutations potently inhibits acute myeloid leukemia cell lines
Neetu Dayal, Clement Opoku-Temeng, Delmis E. Hernandez, M. A. Sooreshjani +3 more
2018Future Medicinal Chemistry18 citations Open access
Semantic Scholar
Suppression of migration, invasion, and metastasis of cisplatin-resistant head and neck squamous cell carcinoma through IKKβ inhibition
Jipei Liao, Zejia Yang, Brandon A. Carter-Cooper, E. Chang +6 more
2020Clinical and Experimental Metastasis17 citations Open access
Semantic Scholar
Analysis of the Mechanisms of Action of Naphthoquinone-Based Anti-Acute Myeloid Leukemia Chemotherapeutics
Michelle Lee, R. Lapidus, D. Ferraris, A. Emadi
2019Molecules17 citations Open access
Semantic Scholar
Aminoisoquinoline benzamides, FLT3 and Src-family kinase inhibitors, potently inhibit proliferation of acute myeloid leukemia cell lines.
Elizabeth Larocque, N. Naganna, Xiao-Chu Ma, Clement Opoku-Temeng +4 more
2017Future Medicinal Chemistry16 citations Open access
Semantic Scholar
SIRT3, a metabolic target linked to ataxia-telangiectasia mutated (ATM) gene deficiency in diffuse large B-cell lymphoma
Kavita Bhalla, Sausan M. Jaber, Kayla Reagan, Arielle Hamburg +14 more
2020Scientific Reports15 citations Open access
Semantic Scholar
Identification of New FLT3 Inhibitors That Potently Inhibit AML Cell Lines via an Azo Click-It/Staple-It Approach.
Xiao-Chu Ma, Jie Zhou, Chang-Hao Wang, Brandon A. Carter-Cooper +7 more
2017ACS Medicinal Chemistry Letters15 citations Open access
Semantic Scholar
Prospective Observational Study of Bisphosphonate-Related Osteonecrosis of the Jaw in Multiple Myeloma: Microbiota Profiling and Cytokine Expression
A. Badros, M. Meddeb, D. Weikel, S. Philip +6 more
2021Frontiers in Oncology13 citations Open access
Semantic Scholar
Deep dissection of the antiviral immune profile of patients with COVID-19
D. Atanackovic, S. Avila, Forat Lutfi, D. de Miguel-Pérez +16 more
2021Communications Biology12 citations Open access
Semantic Scholar
Exploring the Concept of Radiation “Booster Shot” in Combination with an Anti-PD-L1 mAb to Enhance Anti-Tumor Immune Effects in Mouse Pancreas Tumors
M. Chuong, E. Chang, E. Choi, J. Mahmood +3 more
2017Journal of Clinical Oncology and Research12 citations
Semantic Scholar
Exploiting epigenetically mediated changes: Acute myeloid leukemia, leukemia stem cells and the bone marrow microenvironment
A. A. Kogan, R. Lapidus, M. Baer, F. Rassool
2019Advances in Cancer Research11 citations
Semantic Scholar
Amino alkynylisoquinoline and alkynylnaphthyridine compounds potently inhibit acute myeloid leukemia proliferation in mice
N. Naganna, Clement Opoku-Temeng, E. Choi, Elizabeth Larocque +7 more
2019EBioMedicine11 citations Open access
Semantic Scholar
Phase I and pharmacokinetic evaluation of the anti-telomerase agent KML-001 with cisplatin in advanced solid tumors
M. Edelman, R. Lapidus, J. Feliciano, M. Stýblo +3 more
2016Cancer Chemotherapy and Pharmacology11 citations
Semantic Scholar
Simultaneously targeting ErbB family kinases and PI3K in HPV-positive head and neck squamous cell carcinoma.
Zejia Yang, Jipei Liao, L. Schumaker, Brandon A. Carter-Cooper +6 more
2022Oral Oncology9 citations Open access
Semantic Scholar
Hydroxylated Dimeric Naphthoquinones Increase the Generation of Reactive Oxygen Species, Induce Apoptosis of Acute Myeloid Leukemia Cells and Are Not Substrates of the Multidrug Resistance Proteins ABCB1 and ABCG2
R. Lapidus, Brandon A. Carter-Cooper, M. Sadowska, E. Choi +11 more
2016Pharmaceuticals9 citations Open access
Semantic Scholar
Selective targeting of metastatic ovarian cancer using an engineered anthrax prodrug activated by membrane-anchored serine proteases
Nadire Duru, Nisha R. Pawar, Erik W. Martin, Marguerite S Buzza +8 more
2022Proceedings of the National Academy of Sciences of the United States of America8 citations Open access
Semantic Scholar
Cancer-associated macrophage-like cells as prognostic indicators of overall survival in a variety of solid malignancies.
D. Adams, Diane K. Adams, S. Lin, M. Cristofanilli +9 more
20177 citations
Semantic Scholar
Comparative Analysis of Methods for Detecting Isocitrate Dehydrogenase 1 and 2 Mutations and Their Metabolic Consequence, 2-Hydroxyglutarate, in Different Neoplasms
S. Babakoohi, R. Lapidus, R. Faramand, E. Sausville +1 more
2017Applied immunohistochemistry & molecular morphology (Print)7 citations
Semantic Scholar
Rational design of flavivirus E protein vaccine optimizes immunogenicity and mitigates antibody dependent enhancement risk
Yimeng Wang, Andrey Galkin, Xiaoran Shang, Alexander Marin +24 more
2025Nature Communications6 citations
Semantic Scholar
Beta 2-Adrenergic Receptor in Circulating Cancer-Associated Cells Predicts for Increases in Stromal Macrophages in Circulation and Patient Survival in Metastatic Breast Cancer
K. Gardner, M. Cristofanilli, S. Chumsri, R. Lapidus +3 more
2022International Journal of Molecular Sciences6 citations Open access
Semantic Scholar
Targeting Wee1 kinase to suppress proliferation and survival of cisplatin-resistant head and neck squamous cell carcinoma
Zejia Yang, Jipei Liao, R. Lapidus, Xiaoxuan Fan +3 more
2022Cancer Chemotherapy and Pharmacology6 citations
Semantic Scholar
Erwinia asparaginase (crisantaspase) increases plasma levels of serine and glycine
D. Bollino, J. Claiborne, K. Hameed, Xin-Rong Ma +5 more
2022Frontiers in Oncology5 citations Open access
Semantic Scholar
Translatome changes in acute myeloid leukemia cells post-exposure to pegcrisantaspase and venetoclax.
Bandish Kapadia, A. Shetty, D. Bollino, B. Bhandary +6 more
2022Experimental Hematology5 citations Open access
Semantic Scholar
Exosomal PD-L1 expression as non-invasive biomarker for immune checkpoint inhibitors in non-small cell lung cancer
M. Gunasekaran, A. Russo, A. Cardona, D. de Miguel Pérez +5 more
2020Journal of Immunology5 citations
Semantic Scholar
HER3-Targeted Affibodies with Optimized Formats Reduce Ovarian Cancer Progression in a Mouse Xenograft Model
J. Schardt, Madeleine Noonan-Shueh, Jinan M. Oubaid, Alex E Pottash +5 more
2019AAPS Journal5 citations Open access
Semantic Scholar
Micronuclei in Circulating Tumor Associated Macrophages Predicts Progression in Advanced Colorectal Cancer
Dimpal M Kasabwala, R. Bergan, K. Gardner, R. Lapidus +3 more
2022Biomedicines4 citations Open access
Semantic Scholar
Pre-Clinical Activity of Amino-Alcohol Dimeric Naphthoquinones as Potential Therapeutics for Acute Myeloid Leukemia.
D. Ferraris, R. Lapidus, Phuc Truong, D. Bollino +18 more
2021Anti-Cancer Agents in Medicinal Chemistry4 citations
Semantic Scholar
Eight-Day Point of Care CAR T-Cell Manufacturing on Clinimacs Prodigy from Healthy Donors As a Proof-of-Concept Study
K. Hankey, T. Luetkens, S. Avila, J. Mclenithan +15 more
2021Blood4 citations Open access
Semantic Scholar

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