Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

P. Arumugam · SciRah

Researcher profile · Semantic Scholar

P. Arumugam

Share profile

P. Arumugam — researcher profile on SciRah

h-index: 21
Works: 77
Citations: 1,558

Most-cited papers

Pulmonary Macrophage Transplantation Therapy
Takuji Suzuki, P. Arumugam, T. Sakagami, N. Lachmann +10 more
2014Nature285 citations Open access
Semantic Scholar
Improved Human β-globin Expression from Self-inactivating Lentiviral Vectors Carrying the Chicken Hypersensitive Site-4 (cHS4) Insulator Element.
P. Arumugam, J. Scholes, Natalya Perelman, Ping Xia +2 more
2007Molecular Therapy116 citations Open access
Semantic Scholar
Statin as a novel pharmacotherapy of pulmonary alveolar proteinosis
C. McCarthy, Elinor Lee, James P. Bridges, A. Sallese +10 more
2018Nature Communications82 citations Open access
Semantic Scholar
Improved human beta-globin expression from self-inactivating lentiviral vectors carrying the chicken hypersensitive site-4 (cHS4) insulator element.
P. Arumugam, J. Scholes, Natalya Perelman, Ping Xia +2 more
2007Molecular Therapy80 citations
Semantic Scholar
Mechanism of reduction in titers from lentivirus vectors carrying large inserts in the 3'LTR.
F. Urbinati, P. Arumugam, T. Higashimoto, A. Perumbeti +3 more
2009Molecular Therapy75 citations Open access
Semantic Scholar
Genotoxic potential of lineage-specific lentivirus vectors carrying the beta-globin locus control region.
P. Arumugam, T. Higashimoto, F. Urbinati, U. Modlich +6 more
2009Molecular Therapy73 citations Open access
Semantic Scholar
The 3′ Region of the Chicken Hypersensitive Site-4 Insulator Has Properties Similar to Its Core and Is Required for Full Insulator Activity
P. Arumugam, F. Urbinati, C. S. Velu, T. Higashimoto +2 more
2009PLoS ONE71 citations Open access
Semantic Scholar
Targeting cholesterol homeostasis in lung diseases
A. Sallese, Takuji Suzuki, C. McCarthy, James P. Bridges +9 more
2017Scientific Reports69 citations Open access
Semantic Scholar
Neutrophil extracellular traps activate IL-8 and IL-1 expression in human bronchial epithelia.
K. Hudock, M. Collins, M. Imbrogno, J. Snowball +14 more
2020American Journal of Physiology - Lung cellular and Molecular Physiology65 citations Open access
Semantic Scholar
Genetic diminution of circulating prothrombin ameliorates multiorgan pathologies in sickle cell disease mice.
P. Arumugam, E. Mullins, S. Shanmukhappa, B. Monia +6 more
2015Blood57 citations Open access
Semantic Scholar
Perforin Gene Transfer Into Hematopoietic Stem Cells Improves Immune Dysregulation in Murine Models of Perforin Deficiency
M. Carmo, Kimberly A. Risma, P. Arumugam, S. Tiwari +10 more
2014Molecular Therapy52 citations Open access
Semantic Scholar
Successful Correction of the Human Cooley's Anemia β‐Thalassemia Major Phenotype Using a Lentiviral Vector Flanked by the Chicken Hypersensitive Site 4 Chromatin Insulator
P. Malik, P. Arumugam, J.-K. Yee, G. Puthenveetil
2005Annals of the New York Academy of Sciences48 citations
Semantic Scholar
Role of GM-CSF in regulating metabolism and mitochondrial functions critical to macrophage proliferation
M. Wessendarp, Miki Watanabe-Chailland, Serena Liu, T. Stankiewicz +8 more
2021bioRxiv42 citations Open access
Semantic Scholar
Thrombin-PAR1 signaling in pancreatic cancer promotes an immunosuppressive microenvironment
P. Schweickert, Yi Yang, E. White, G. Cresswell +7 more
2020Journal of Thrombosis and Haemostasis41 citations Open access
Semantic Scholar
RhoA GTPase controls cytokinesis and programmed necrosis of hematopoietic progenitors
Xuan Zhou, M. Florian, P. Arumugam, Xiaoyi Chen +5 more
2013Journal of Experimental Medicine41 citations Open access
Semantic Scholar
Genetic therapy for beta-thalassemia: from the bench to the bedside.
P. Arumugam, P. Malik
2010Hematology. American Society of Hematology. Education Program41 citations Open access
Semantic Scholar
Placenta growth factor augments airway hyperresponsiveness via leukotrienes and IL-13.
Marthe-Sandrine Eiymo Mwa Mpollo, E. Brandt, S. Shanmukhappa, P. Arumugam +13 more
2015Journal of Clinical Investigation35 citations Open access
Semantic Scholar
FOXM1 nuclear transcription factor translocates into mitochondria and inhibits oxidative phosphorylation
Markaisa Black, P. Arumugam, Samriddhi Shukla, A. Pradhan +4 more
2020Molecular Biology of the Cell34 citations Open access
Semantic Scholar
Gene Therapy for beta-thalassemia.
P. Malik, P. Arumugam
200534 citations Open access
Semantic Scholar
Long-Term Safety and Efficacy of Gene-Pulmonary Macrophage Transplantation Therapy of PAP in Csf2ra-/- Mice.
P. Arumugam, Takuji Suzuki, K. Shima, C. McCarthy +10 more
2019Molecular Therapy30 citations Open access
Semantic Scholar
Function and Safety of Lentivirus-Mediated Gene Transfer for CSF2RA-Deficiency
M. Hetzel, Takuji Suzuki, A. R. Hashtchin, P. Arumugam +9 more
2017Human Gene Therapy Methods21 citations Open access
Semantic Scholar
Lentiviral gene therapy with reduced-intensity conditioning for sickle cell disease: a phase 1/2 trial
M. Grimley, Stella M. Davies, Archana Shrestha, Amy Shova +20 more
2025Nature Medicine20 citations Open access
Semantic Scholar
Safety and Efficacy of Aru-1801 in Patients with Sickle Cell Disease: Early Results from the Phase 1/2 Momentum Study of a Modified Gamma Globin Gene Therapy and Reduced Intensity Conditioning
M. Grimley, M. Asnani, A. Shrestha, S. Felker +10 more
2021Blood20 citations Open access
Semantic Scholar
Foamy Virus Vector Carries a Strong Insulator in Its Long Terminal Repeat Which Reduces Its Genotoxic Potential
Michael Goodman, P. Arumugam, Devin M. Pillis, Anastacia Loberg +9 more
2017Journal of Virology18 citations Open access
Semantic Scholar
Elimination of the fibrinogen integrin αMβ2-binding motif improves renal pathology in mice with sickle cell anemia.
M. Nasimuzzaman, P. Arumugam, E. Mullins, Jeanne M. James +6 more
2019Blood Advances16 citations Open access
Semantic Scholar
Pigtailed macaques as a model to study long-term safety of lentivirus vector-mediated gene therapy for hemoglobinopathies
H. Kiem, P. Arumugam, C. Burtner, Catherine F Fox +4 more
2014Molecular Therapy: Methods & Clinical Development15 citations Open access
Semantic Scholar
High Level of Perforin Expression Is Required for Effective Correction of Hemophagocytic Lymphohistiocytosis
S. Tiwari, Adrianne E Hontz, Catherine E. Terrell, P. Arumugam +4 more
2016Human Gene Therapy14 citations Open access
Semantic Scholar
Genotoxic Potential of Lineage-specific Lentivirus Vectors Carrying the β-Globin Locus Control Region.
P. Arumugam, T. Higashimoto, F. Urbinati, U. Modlich +6 more
2009Molecular Therapy14 citations Open access
Semantic Scholar
A Murine Model of Hereditary Pulmonary Alveolar Proteinosis Caused by Homozygous Csf2ra Gene Disruption.
K. Shima, P. Arumugam, A. Sallese, Yuko Horia +8 more
2022American Journal of Physiology - Lung cellular and Molecular Physiology13 citations Open access
Semantic Scholar
Early Results from a Phase 1/2 Study of Aru-1801 Gene Therapy for Sickle Cell Disease (SCD): Manufacturing Process Enhancements Improve Efficacy of a Modified Gamma Globin Lentivirus Vector and Reduced Intensity Conditioning Transplant
M. Grimley, M. Asnani, A. Shrestha, S. Felker +10 more
202012 citations Open access
Semantic Scholar
Use of the in Vitro Immortalization Assay to Quantify the Impact of Integration Spectrum and Vector Design on Insertional Mutagenesis
U. Modlich, Julia Sürth, D. Zychlinski, Johann Meyer +7 more
20114 citations
Semantic Scholar
A toxicology study of Csf2ra complementation and pulmonary macrophage transplantation therapy of hereditary PAP in mice
P. Arumugam, B. Carey, K. Wikenheiser-Brokamp, Jeffrey Krischer +19 more
2024Molecular Therapy: Methods & Clinical Development3 citations Open access
Semantic Scholar
A Dried Blood Spot Test for Diagnosis of Autoimmune Pulmonary Alveolar Proteinosis
B. Carey, C. Chalk, J. Stock, Andrea Tóth +5 more
2022JIM - Journal of Immunological Methods3 citations Open access
Semantic Scholar
Safety Of a Gamma Globin Expressing Lentivirus Vector In a Non-Human Primate Model For Gene Therapy Of Sickle Cell Disease
H. Kiem, P. Arumugam, B. Christopher, J. Adair +3 more
20133 citations
Semantic Scholar
Self-Inactivating Lentiviral Vectors Flanked by a Chromatin Insulator Element Result in Increased, Consistent Expression of Human Beta Globin.
P. Arumugam, J. Scholes, Natalya Perelman, A. Zarzuela +1 more
20053 citations
Semantic Scholar
Gene Therapy with Reduced-Intensity Conditioning for Sickle Cell Disease
Stella M. Davies, Michael Grimley, Archana Shrestha, Amy Shova +20 more
2025Transplantation and Cellular Therapy2 citations Open access
Semantic Scholar
P1453: STABLE TRANSDUCTION OF FETAL HEMOGLOBIN IN PATIENTS WITH SICKLE CELL DISEASE IN THE PHASE 1/2 MOMENTUM STUDY OF ARU-1801 GENE THERAPY AND REDUCED INTENSITY CONDITIONING
M. Grimley, M. Kent, M. Asnani, A. Shrestha +11 more
2022HemaSphere2 citations Open access
Semantic Scholar
Gene Therapy for Hemophagocytic Lymphohistiocytosis (HLH): Fixing a Criticial ‘Circuit Breaker’ in the Immune System.
M. Jordan, M. Carmo, S. Tiwari, P. Arumugam +3 more
20122 citations
Semantic Scholar
Preclinical studies supporting a first-in-human trial of pulmonary macrophage transplantation therapy of CSF2RA-associaited PAP
P. Arumugam, B. Carey, L. Trump-Durbin, M. Wessendarp +9 more
2023Rare ILD/DPLD1 citations
Semantic Scholar
237. Genetic Therapy for Perforin Deficiency Associated Hemophagocytic Lymphohistiocytosis Requires High Level Expression of the Perforin Gene for Adequate Correction
S. Tiwari, Adrianne E Hontz, Catherine E. Terrell, P. Arumugam +5 more
20151 citations Open access
Semantic Scholar
Lentivirus vectors for gene therapy for hemoglobinopathies
P. Arumugam, F. Urbinati, T. Higashimoto, A. Perumbeti +1 more
20081 citations
Semantic Scholar
Mechanism of Reduction in Titers from Lentivirus Vectors Carrying Chromatin Insulator Elements in the 3′ LTR
F. Urbinati, P. Arumugam, T. Higashimoto, A. Perumbeti +2 more
20081 citations
Semantic Scholar
B28-23 Gm-csf Signaling Deficiency Causes Marked Pulmonary Lymphocytosis Due to Alveolar Macrophage-mediated Recruitment, Altered Lymphoid-myeloid Lineage Commitment, and Local Proliferation
P. Arumugam, C. Williams, M. Guo, M. Wessendarp +4 more
2026American Journal of Respiratory and Critical Care Medicine0 citations
Semantic Scholar
B76-04 Alpha-1 Knockout Mice Have Increased Lung Inflammatory Cytokines That Correlate With Protease Activities
R. Pasula, M. Imbrogno, A. Dasgupta, B. C. Carey +3 more
2026American Journal of Respiratory and Critical Care Medicine0 citations
Semantic Scholar
B95-10 A First-in-human Study of Pulmonary Macrophage Transplantation Therapy of Hereditary Pulmonary Alveolar Proteinosis
B. Trapnell, P. Arumugam, B. Carey, J. Krischer +14 more
2026American Journal of Respiratory and Critical Care Medicine0 citations
Semantic Scholar
GM-CSF Programs Alveolar Macrophages to Maintain Pulmonary Lymphocyte Homeostasis
P. Arumugam, Min-Zhe Guo, C. Williams, B. Carey +10 more
2026bioRxiv0 citations Open access
Semantic Scholar
Angiotensin signaling is essential for stress erythropoiesis but causes retention of dysfunctional mitochondria in RBCs
Parul Rai, Swarnava Roy, P. Arumugam, Diamantis G. Konstantinidis +5 more
2026JCI Insight0 citations Open access
Semantic Scholar
Disruption of GM-CSF Signaling in Pap Increases Lymphoid Lineage Commitment and Pulmonary Lymphocytosis
B. C. Trapnell, P. Arumugam, C. Williams, D. Read +6 more
2024A70. MOLECULAR INSIGHTS INTO ILD PATHOGENESIS0 citations
Semantic Scholar
A Macrophage (Drug Product)- Delivery Device (Bronchoscope) Compatibility Study
P. Arumugam, L. Trump-Durbin, M. Wessendarp, S. Spoorthi +4 more
2024B63. BRONCHOPULMONARY DYSPLASIA AND DEVELOPMENTAL LUNG DISEASE0 citations
Semantic Scholar
A First-in-Human Clinical Trial of Pulmonary Macrophage Transplantation Therapy of Hereditary Pulmonary Alveolar Proteinosis Caused by Biallelic CSF2RA Mutations
B. C. Trapnell, P. Arumugam, B. Carey, L. Trump-Durbin +8 more
2024B29. BIOMARKERS AND NEW THERAPEUTICS TARGETS IN LUNG FIBROSIS0 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

P. Malik×28
Invite
P. Malik — researcher profile on SciRah
M. Wessendarp×12
Invite
M. Wessendarp — researcher profile on SciRah
B. Carey×11
Invite
B. Carey — researcher profile on SciRah
C. Chalk×10
Invite
C. Chalk — researcher profile on SciRah

×8

Invite

Takuji Suzuki — researcher profile on SciRah

Invite

B. Trapnell — researcher profile on SciRah

Invite

K. Shima — researcher profile on SciRah

Invite

Ping Xia — researcher profile on SciRah

Invite

F. Urbinati — researcher profile on SciRah

T. Higashimoto×6

Invite

T. Higashimoto — researcher profile on SciRah

Invite

A. Sallese — researcher profile on SciRah

Invite

S. Tiwari — researcher profile on SciRah