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Kelly M. Ramsbottom · SciRah

Researcher profile · Semantic Scholar

Kelly M. Ramsbottom

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Kelly M. Ramsbottom — researcher profile on SciRah

h-index: 20
Works: 30
Citations: 1,523

Most-cited papers

Tumor immune evasion arises through loss of TNF sensitivity
Conor J. Kearney, S. Vervoort, S. Hogg, Kelly M. Ramsbottom +14 more
2018Science immunology346 citations Open access
Semantic Scholar
Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time
J. Trapani, M. Jenkins, J. Rudd-Schmidt, Jamie Lopez +4 more
2015Journal of Experimental Medicine221 citations Open access
Semantic Scholar
Natural Killer Cells Suppress T Cell-Associated Tumor Immune Evasion.
Andrew J. Freeman, S. Vervoort, Kelly M. Ramsbottom, M. Kelly +5 more
2019Cell Reports115 citations Open access
Semantic Scholar
CDK4/6 inhibition promotes anti-tumor immunity through the induction of T cell memory.
Emily J. Lelliott, Isabella Y. Kong, Magnus Zethoven, Kelly M. Ramsbottom +20 more
2021Cancer Discovery109 citations Open access
Semantic Scholar
Antagonism of IAPs Enhances CAR T-cell Efficacy
Jessica Michie, P. Beavis, Andrew J. Freeman, S. Vervoort +11 more
2019Cancer immunology research80 citations Open access
Semantic Scholar
PD-L1 and IAPs co-operate to protect tumors from cytotoxic lymphocyte-derived TNF
Conor J. Kearney, N. Lalaoui, Andrew J. Freeman, Kelly M. Ramsbottom +2 more
2017Cell Death and Differentiation79 citations Open access
Semantic Scholar
SUGAR-seq enables simultaneous detection of glycans, epitopes, and the transcriptome in single cells
Conor J. Kearney, S. Vervoort, Kelly M. Ramsbottom, Izabela Todorovski +11 more
2021Science Advances78 citations Open access
Semantic Scholar
Regulation of asymmetric cell division and polarity by Scribble is not required for humoral immunity
E. Hawkins, J. Oliaro, A. Kallies, G. Belz +12 more
2013Nature Communications66 citations Open access
Semantic Scholar
Loss of DNAM-1 ligand expression by acute myeloid leukemia cells renders them resistant to NK cell killing
Conor J. Kearney, Kelly M. Ramsbottom, I. Voskoboinik, P. Darcy +1 more
2016Oncoimmunology54 citations Open access
Semantic Scholar
Cutting Edge: DNAX Accessory Molecule 1–Deficient CD8+ T Cells Display Immunological Synapse Defects That Impair Antitumor Immunity
Kelly M. Ramsbottom, E. Hawkins, R. Shimoni, M. McGrath +4 more
2014Journal of Immunology48 citations Open access
Semantic Scholar
Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance
M. Wagle, S. Vervoort, M. Kelly, Willem Van Der Byl +22 more
2021Nature Communications43 citations Open access
Semantic Scholar
Asymmetric cell division during T cell development controls downstream fate
K. Pham, R. Shimoni, M. Charnley, M. Ludford-Menting +13 more
2015Journal of Cell Biology39 citations Open access
Semantic Scholar
HDAC Inhibitor Panobinostat Engages Host Innate Immune Defenses to Promote the Tumoricidal Effects of Trastuzumab in HER2+ Tumors.
Mikolaj Medon, E. Vidacs, S. Vervoort, Jason Li +9 more
2017Cancer Research28 citations Open access
Semantic Scholar
NKG7 Enhances CD8+ T Cell Synapse Efficiency to Limit Inflammation
Emily J. Lelliott, Kelly M. Ramsbottom, M. Dowling, Carolyn Shembrey +9 more
2022Frontiers in Immunology27 citations Open access
Semantic Scholar
HOIP limits anti‐tumor immunity by protecting against combined TNF and IFN‐gamma‐induced apoptosis
Andrew J. Freeman, S. Vervoort, Jessica Michie, Kelly M. Ramsbottom +3 more
2021EMBO Reports27 citations Open access
Semantic Scholar
The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
Willem Van Der Byl, S. Nüssing, Timothy J. Peters, Antonio Ahn +24 more
2024Immunity25 citations Open access
Semantic Scholar
A novel immunogenic mouse model of melanoma for the preclinical assessment of combination targeted and immune-based therapy
Emily J. Lelliott, C. Cullinane, Claire A. Martin, Rachael Walker +13 more
2019Scientific Reports23 citations Open access
Semantic Scholar
DOCK8 Drives Src-Dependent NK Cell Effector Function
Conor J. Kearney, S. Vervoort, Kelly M. Ramsbottom, Andrew J. Freeman +9 more
2017Journal of Immunology23 citations Open access
Semantic Scholar
BET Inhibition Enhances TNF-Mediated Antitumor Immunity
Lisa C. Wellinger, S. Hogg, Dane M. Newman, T. Friess +18 more
2021Cancer immunology research22 citations Open access
Semantic Scholar
Combined BRAF, MEK, and CDK4/6 Inhibition Depletes Intratumoral Immune-Potentiating Myeloid Populations in Melanoma
Emily J. Lelliott, S. Mangiola, Kelly M. Ramsbottom, Magnus Zethoven +14 more
2020Cancer immunology research22 citations
Semantic Scholar
Lethal Giant Larvae 1 Tumour Suppressor Activity Is Not Conserved in Models of Mammalian T and B Cell Leukaemia
E. Hawkins, J. Oliaro, Kelly M. Ramsbottom, S. Ting +7 more
2014PLoS ONE19 citations Open access
Semantic Scholar
Intracellular zinc protects tumours from T cell-mediated cytotoxicity
Emily J. Lelliott, Jonathan Naddaf, K. Ganio, Jessica Michie +14 more
2024Cell Death and Differentiation13 citations Open access
Semantic Scholar
A Method for Detecting Intracellular Perforin in Mouse Lymphocytes
A. Brennan, Imran G. House, J. Oliaro, Kelly M. Ramsbottom +4 more
2014Journal of Immunology12 citations Open access
Semantic Scholar
High efficiency CRISPR knock-in demonstrates that TCF1 is insufficient to reverse T cell exhaustion
Maria N. de Menezes, Amanda X. Y. Chen, Nihali Kulkarni, S. Sampurno +10 more
2026Nature Communications5 citations Open access
Semantic Scholar
CDK4/6 inhibition enhances CAR-T cell therapy in solid tumors
Emily J. Lelliott, Jonathan Naddaf, Kun-Hui Lu, Katherine D Cummins +12 more
2026Molecular Therapy1 citations Open access
Semantic Scholar
Abstract LT02: Regulation of Exhausted CD8+ T cell Differentiation by IKZF Transcription Factors
Sinead M. Reading, Isabelle Munoz, Maria N. de Menezes, Nicole Y. L. Saw +12 more
2024Cancer Research1 citations
Semantic Scholar
Failed CTL / NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time
J. Trapani, M. Jenkins, J. Rudd-Schmidt, Jamie Lopez +4 more
20151 citations
Semantic Scholar
Abstract PR01: Regulation of exhausted CD8+ T cell differentiation by IKZF transcription factors
Sinead M. Reading, Isabelle Munoz, Maria N. de Menezes, Nicole Y. L. Saw +12 more
2023Cancer immunology research0 citations
Semantic Scholar
Class I/II Histone Deacetylase Inhibitors Are a Potential Therapeutic For Notch-1 Driven T Cell Acute Lymphoblastic Leukemia
M. Waibel, E. Hawkins, Kelly M. Ramsbottom, B. Martin +1 more
20130 citations
Semantic Scholar
Antitumor Immunity Immunological Synapse Defects That Impair T Cells Display + Deficient CD8 - Cutting Edge: DNAX Accessory Molecule 1
M. Smyth, J. Oliaro, M. McGrath, C. Chan +4 more
20130 citations
Semantic Scholar

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