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Carolyn Shembrey · SciRah

Researcher profile · Semantic Scholar

Carolyn Shembrey

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Carolyn Shembrey — researcher profile on SciRah

h-index: 8
Works: 21
Citations: 350

Most-cited papers

Surgical stress response and promotion of metastasis in colorectal cancer: a complex and heterogeneous process
Corina Camille Behrenbruch, Carolyn Shembrey, S. Paquet-Fifield, C. Mølck +5 more
2018Clinical and Experimental Metastasis63 citations Open access
Semantic Scholar
Tight Junction Protein Claudin-2 Promotes Self-Renewal of Human Colorectal Cancer Stem-like Cells.
S. Paquet-Fifield, S. L. Koh, Lesley Cheng, Laura M Beyit +19 more
2018Cancer Research62 citations
Semantic Scholar
Serine biosynthesis is a metabolic vulnerability in FLT3-ITD-driven acute myeloid leukaemia.
Stefan Bjelosevic, Emily Gruber, A. Newbold, Carolyn Shembrey +12 more
2021Cancer Discovery55 citations Open access
Semantic Scholar
Impact of Tumor and Immunological Heterogeneity on the Anti-Cancer Immune Response
Carolyn Shembrey, N. Huntington, F. Hollande
2019Cancers46 citations Open access
Semantic Scholar
Laminin 521 enhances self-renewal via Stat3 activation and promotes tumor progression in Colorectal Cancer.
Yan Qin, Carolyn Shembrey, Jai Smith, S. Paquet-Fifield +6 more
2020Cancer Letters39 citations
Semantic Scholar
NKG7 Enhances CD8+ T Cell Synapse Efficiency to Limit Inflammation
Emily J. Lelliott, Kelly M. Ramsbottom, M. Dowling, Carolyn Shembrey +9 more
2022Frontiers in Immunology27 citations Open access
Semantic Scholar
Principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision
Carolyn Shembrey, Ray Yang, Joshua M. L. Casan, Wen-Xin Hu +9 more
2024Science Advances23 citations Open access
Semantic Scholar
Longitudinal Monitoring of Intra-Tumoural Heterogeneity Using Optical Barcoding of Patient-Derived Colorectal Tumour Models
Carolyn Shembrey, Jai Smith, M. Grandin, Nathalia Williams +7 more
2022Cancers8 citations Open access
Semantic Scholar
Targeting of TP53-independent cell cycle checkpoints overcomes FOLFOX resistance in Metastatic Colorectal Cancer
Corina Camille Behrenbruch, M. Foroutan, P. Lind, Jai Smith +20 more
2021bioRxiv8 citations Open access
Semantic Scholar
A new natural killer cell-specific gene signature predicting recurrence in colorectal cancer patients
Carolyn Shembrey, M. Foroutan, F. Hollande
2023Frontiers in Immunology6 citations Open access
Semantic Scholar
Phenotypic Consequences of SLC25A40-ABCB1 Fusions beyond Drug Resistance in High-Grade Serous Ovarian Cancer
K. Pishas, K. Cowley, A. Pandey, T. Hoang +14 more
2021Cancers5 citations Open access
Semantic Scholar
CRISPR in clinical oncology: translational advances from molecular diagnostics to therapeutics
S. Grigg, Carolyn Shembrey, M. Fareh, P. Blombery +3 more
2026Nature Reviews Clinical Oncology3 citations
Semantic Scholar
Systematic silencing of oncogenic fusion transcripts with ultra-precise CRISPR-Cas13b
Wen-Xin Hu, Hong-Lin Chen, Joshua M. L. Casan, Carolyn Shembrey +10 more
2025bioRxiv2 citations Open access
Semantic Scholar
A new highly-specific Natural Killer cell-specific gene signature predicting recurrence in colorectal cancer patients
Carolyn Shembrey, C. Behrenbruch, B. Loveday, A. Heriot +2 more
2022bioRxiv2 citations Open access
Semantic Scholar
Reprogramming of serine metabolism is an actionable vulnerability in FLT3-ITD driven acute myeloid leukaemia
Stefan Bjelosevic, Emily Gruber, A. Newbold, L. Kats +9 more
2020bioRxiv2 citations Open access
Semantic Scholar
Target RNA abundance controls the collateral activity of RfxCas13d in human cells and zebrafish embryos
Hong-Lin Chen, Wen-Xin Hu, V. Impicciche, G. Singh +14 more
2026bioRxiv1 citations Open access
Semantic Scholar
Molecular principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision
Carolyn Shembrey, Ray Yang, Joshua M. L. Casan, Wen-Xin Hu +7 more
2023bioRxiv1 citations Open access
Semantic Scholar
Phase-Separated RNA Condensates Govern Cas13 Target Accessibility and Cleavage
Gurjeet Kaur Gill Jagjeet Singh, Wen-Xing Hu, Carolyn Shembrey, Adrian W. Hodel +4 more
2026bioRxiv0 citations Open access
Semantic Scholar
Programmable and selective silencing of oncogenic fusion transcripts by CRISPR-Cas13b via breakpoint sequence recognition
Wen-Xin Hu, Hong-Lin Chen, Steven He, Joshua M. L. Casan +17 more
2026Science Advances0 citations Open access
Semantic Scholar
3002 – REPROGRAMMING OF SERINE METABOLISM IS A METABOLIC VULNERABILITY IN FMS-LIKE TYROSINE KINASE 3 (FLT3) MUTANT ACUTE MYELOID LEUKAEMIA
Stefan Bjelosevic, Emily Gruber, A. Newbold, Carolyn Shembrey +8 more
20200 citations Open access
Semantic Scholar
Optical barcoding highlights novel characteristics of treatment resistant cells in metastatic colorectal cancer
F. Hollande, C. Behrenbruch, Carolyn Shembrey, Xue Pu +4 more
20180 citations
Semantic Scholar

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