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J. Rudd-Schmidt · SciRah

Researcher profile · Semantic Scholar

J. Rudd-Schmidt

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J. Rudd-Schmidt — researcher profile on SciRah

h-index: 9
Works: 19
Citations: 497

Most-cited papers

Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time
J. Trapani, M. Jenkins, J. Rudd-Schmidt, Jamie Lopez +4 more
2015Journal of Experimental Medicine221 citations Open access
Semantic Scholar
Rapid and Unidirectional Perforin Pore Delivery at the Cytotoxic Immune Synapse
Jamie Lopez, M. Jenkins, J. Rudd-Schmidt, A. Brennan +4 more
2013Journal of Immunology91 citations Open access
Semantic Scholar
Lipid order and charge protect killer T cells from accidental death
J. Rudd-Schmidt, Adrian W. Hodel, T. Noori, Jamie Lopez +6 more
2019Nature Communications81 citations Open access
Semantic Scholar
Exploration of a Series of 5-Arylidene-2-thioxoimidazolidin-4-ones as Inhibitors of the Cytolytic Protein Perforin
J. Spicer, G. Lena, D. Lyons, K. Huttunen +12 more
2013Journal of Medicinal Chemistry29 citations Open access
Semantic Scholar
Labeling phospholipid membranes with lipid mimetic luminescent metal complexes.
Adam I. Mechler, B. Stringer, M. Mubin, Egan H. Doeven +3 more
2014Biochimica et Biophysica Acta21 citations Open access
Semantic Scholar
A cell-based functional assay that accurately links genotype to phenotype in Familial HLH.
T. Noori, J. Rudd-Schmidt, A. Kane, K. Frith +7 more
2023Blood13 citations
Semantic Scholar
Acidic pH can attenuate immune killing through inactivation of perforin
Adrian W. Hodel, J. Rudd-Schmidt, T. Noori, Christopher J. Lupton +4 more
2025EMBO Reports12 citations Open access
Semantic Scholar
Lipid specificity of the immune effector perforin
Adrian W. Hodel, J. Rudd-Schmidt, J. Trapani, I. Voskoboinik +1 more
2020bioRxiv10 citations Open access
Semantic Scholar
Distinguishing perforin-mediated lysis and granzyme-dependent apoptosis.
J. Rudd-Schmidt, J. Trapani, I. Voskoboinik
2019Methods in Enzymology9 citations
Semantic Scholar
Severely impaired CTL killing is a feature of the neurological disorder Niemann-Pick Syndrome type C1.
Daniela Castiblanco, J. Rudd-Schmidt, T. Noori, V. Sutton +11 more
2022Blood8 citations
Semantic Scholar
ALFA-PRF: a novel approach to detect murine perforin release from CTLs into the immune synapse
J. Rudd-Schmidt, R. Laine, T. Noori, A. Brennan +1 more
2022Frontiers in Immunology4 citations Open access
Semantic Scholar
Failed CTL / NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time
J. Trapani, M. Jenkins, J. Rudd-Schmidt, Jamie Lopez +4 more
20151 citations
Semantic Scholar
Differential perforin sensitivity drives lineage-dependent resistance to CAR T-cell killing in blood cancer cell lines
Adrian W. Hodel, T. Noori, J. Rudd-Schmidt, Scott A. Williams +5 more
2026Blood Advances0 citations Open access
Semantic Scholar
Cholesterol remodels the endoplasmic reticulum to control myofibroblastic CAF function
Srimayee Vaidyanathan, N. Yuwono, E. Mok, Jessica L. Chitty +6 more
2026bioRxiv0 citations
Semantic Scholar
Novel chimeric PD-L1::PD-L2 fusion and immune evasion in lymphoma
Joshua M. L. Casan, Fatimah B Jalud, Kaitlyn Kew, I. Tiong +7 more
2026npj Precision Oncology0 citations Open access
Semantic Scholar
Visualising Cytotoxic Lymphocytes to Understand Human Disease
J. Rudd-Schmidt, Adrian W. Hodel, Daniela Castiblanco, T. Noori +2 more
2025Visualising Cytotoxic Lymphocytes to Understand Human Disease0 citations Open access
Semantic Scholar
Acidic pH attenuates immune killing through inactivation of perforin
Adrian W. Hodel, J. Rudd-Schmidt, T. Noori, Christopher J. Lupton +4 more
2024bioRxiv0 citations Open access
Semantic Scholar
Peptide-membrane interactions Faraday Discussions
Adrian W. Hodel, J. Rudd-Schmidt, J. Trapani
20210 citations
Semantic Scholar
Delivery at the Cytotoxic Immune Synapse Rapid and Unidirectional Perforin Pore
Jamie Lopez, M. Jenkins, J. Rudd-Schmidt, A. Brennan +4 more
20130 citations
Semantic Scholar

Frequent co-authors

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I. Voskoboinik×15
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I. Voskoboinik — researcher profile on SciRah
J. Trapani×10
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J. Trapani — researcher profile on SciRah
Adrian W. Hodel×9
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Adrian W. Hodel — researcher profile on SciRah
T. Noori×8
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T. Noori — researcher profile on SciRah

×6

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Jamie Lopez — researcher profile on SciRah

B. Hoogenboom×5

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M. Jenkins — researcher profile on SciRah

Stuart I. Mannering×4

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A. Brennan — researcher profile on SciRah

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J. Trapani — researcher profile on SciRah

Kelly M. Ramsbottom×2

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