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P. Schirmacher · SciRah

Researcher profile · Semantic Scholar

P. Schirmacher

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P. Schirmacher — researcher profile on SciRah

h-index: 99
Works: 909
Citations: 52K

Most-cited papers

The 2019 WHO classification of tumours of the digestive system
I. Nagtegaal, R. Odze, D. Klimstra, V. Paradis +5 more
2019Histopathology3,539 citations Open access
Semantic Scholar
NASH limits anti-tumour surveillance in immunotherapy-treated HCC
D. Pfister, N. Núñez, R. Pinyol, O. Govaere +106 more
2021Nature1,147 citations Open access
Semantic Scholar
Sarcoma classification by DNA methylation profiling
C. Koelsche, D. Schrimpf, D. Stichel, M. Sill +107 more
2021Nature Communications469 citations Open access
Semantic Scholar
Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers.
P. Horák, C. Heining, S. Kreutzfeldt, B. Hutter +55 more
2021Cancer Discovery241 citations Open access
Semantic Scholar
Molecular characterisation of hepatocellular carcinoma in patients with non-alcoholic steatohepatitis
R. Pinyol, S. Torrecilla, Huan Wang, C. Montironi +31 more
2021Journal of Hepatology214 citations Open access
Semantic Scholar
Measurement of tumor mutational burden (TMB) in routine molecular diagnostics: in silico and real‐life analysis of three larger gene panels
V. Endris, I. Buchhalter, M. Allgäuer, E. Rempel +16 more
2019International Journal of Cancer108 citations Open access
Semantic Scholar
Integrative Analysis Defines Distinct Prognostic Subgroups of Intrahepatic Cholangiocarcinoma
B. Goeppert, R. Toth, S. Singer, T. Albrecht +14 more
2019Hepatology84 citations Open access
Semantic Scholar
The Pathology of Severe COVID-19-Related Lung Damage.
F. Kommoss, C. Schwab, Luca Tavernar, Johannes Schreck +5 more
2020Deutsches Ärzteblatt International83 citations Open access
Semantic Scholar
Harmonization and Standardization of Panel-Based Tumor Mutational Burden (TMB) Measurement: Real-World Results and Recommendations of the QuIP Study.
A. Stenzinger, V. Endris, J. Budczies, S. Merkelbach-Bruse +31 more
2020Journal of Thoracic Oncology82 citations Open access
Semantic Scholar
Artificial Intelligence and Pathology: from Principles to Practice and Future Applications in Histomorphology and Molecular Profiling.
A. Stenzinger, M. Alber, M. Allgäuer, Philipp Jurmeister +11 more
2021Seminars in Cancer Biology74 citations Open access
Semantic Scholar
Diagnosis of digestive system tumours
M. Washington, R. Goldberg, G. Chang, P. Limburg +12 more
2020International Journal of Cancer65 citations Open access
Semantic Scholar
Development and prognostic relevance of a histologic grading and staging system for alcohol-related liver disease.
C. Lackner, R. Stauber, S. Davies, Hüseyin Denk +26 more
2021Journal of Hepatology63 citations Open access
Semantic Scholar
Interferon‐induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20
D. Stadler, M. Kächele, Alisha N. Jones, J. Hess +21 more
2021EMBO Reports63 citations Open access
Semantic Scholar
Distinct Molecular Phenotype of Sporadic Colorectal Cancers Among Young Patients Based on Multi-omics Analysis
A. Holowatyj, B. Gigic, E. Herpel, A. Scalbert +29 more
2019Gastroenterology61 citations Open access
Semantic Scholar
A gene expression signature associated with B cells predicts benefit from immune checkpoint blockade in lung adenocarcinoma
J. Budczies, M. Kirchner, K. Kluck, Daniel Kazdal +15 more
2021Oncoimmunology57 citations Open access
Semantic Scholar
YAP-dependent induction of UHMK1 supports nuclear enrichment of the oncogene MYBL2 and proliferation in liver cancer cells
Teng Wei, S. Weiler, M. Tóth, C. Sticht +11 more
2019Oncogene56 citations
Semantic Scholar
Testing NTRK testing: Wet‐lab and in silico comparison of RNA‐based targeted sequencing assays
N. Pfarr, M. Kirchner, U. Lehmann, J. Leichsenring +22 more
2020Genes, Chromosomes and Cancer54 citations
Semantic Scholar
TAZ target gene ITGAV regulates invasion and feeds back positively on YAP and TAZ in liver cancer cells.
S. Weiler, T. Lutz, M. Bissinger, C. Sticht +4 more
2020Cancer Letters53 citations
Semantic Scholar
The BRCA2 mutation status shapes the immune phenotype of prostate cancer
M. Jenzer, Peter Keß, Cathleen Nientiedt, V. Endris +17 more
2019Cancer Immunology and Immunotherapy49 citations Open access
Semantic Scholar
Integrative analysis reveals early and distinct genetic and epigenetic changes in intraductal papillary and tubulopapillary cholangiocarcinogenesis
B. Goeppert, D. Stichel, R. Toth, S. Fritzsche +15 more
2021Gut47 citations Open access
Semantic Scholar
Profiling of gallbladder carcinoma reveals distinct miRNA profiles and activation of STAT1 by the tumor suppressive miRNA-145-5p
B. Goeppert, F. Truckenmueller, A. Ori, V. Fritz +14 more
2019Scientific Reports45 citations Open access
Semantic Scholar
YAP Orchestrates Heterotypic Endothelial Cell Communication via HGF/c-MET Signaling in Liver Tumorigenesis
Stefan Thomann, S. Weiler, S. Marquard, F. Rose +16 more
2020Cancer Research44 citations Open access
Semantic Scholar
Peer Review #3 of "Clinical characteristics and prognostic value of MEX3A mRNA in liver cancer (v0.1)"
Ding-Quan Yang, Y. Jiao, Yan-Qing Li, Xue-Dong Fang +195 more
202044 citations Open access
Semantic Scholar
Histone H3K27 demethylase KDM6A is an epigenetic gatekeeper of mTORC1 signalling in cancer
Steffie Revia, A. Seretny, L. Wendler, A. Banito +17 more
2021Gut41 citations Open access
Semantic Scholar
Yes-associated protein (YAP) induces a secretome phenotype and transcriptionally regulates plasminogen activator Inhibitor-1 (PAI-1) expression in hepatocarcinogenesis
S. Marquard, Stefan Thomann, S. Weiler, M. Bissinger +9 more
2020Cell communication and signaling : CCS40 citations Open access
Semantic Scholar
NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis
S. Luiken, A. Fraas, M. Bieg, Raisatun N. Sugiyanto +15 more
2020Oncogene39 citations Open access
Semantic Scholar
Deciphering the immunosuppressive tumor microenvironment in ALK- and EGFR-positive lung adenocarcinoma
J. Budczies, M. Kirchner, K. Kluck, Daniel Kazdal +19 more
2021Cancer Immunology and Immunotherapy38 citations Open access
Semantic Scholar
The immune microenvironment in EGFR- and ERBB2-mutated lung adenocarcinoma
M. Kirchner, K. Kluck, R. Brandt, A. Volckmar +20 more
2021ESMO Open36 citations Open access
Semantic Scholar
Quantifying potential confounders of panel-based tumor mutational burden (TMB) measurement.
J. Budczies, Daniel Kazdal, M. Allgäuer, P. Christopoulos +9 more
2020Lung Cancer36 citations
Semantic Scholar
YAP‐induced Ccl2 expression is associated with a switch in hepatic macrophage identity and vascular remodelling in liver cancer
Stefan Thomann, S. Weiler, Teng Wei, C. Sticht +10 more
2021Liver international (Print)35 citations Open access
Semantic Scholar
Trailblazing Precision Medicine in Europe: a joint view by Genomic Medicine Sweden and the Centers for Personalized Medicine, ZPM, in Germany.
A. Stenzinger, A. Edsjö, C. Ploeger, Mikaela Friedman +13 more
2021Seminars in Cancer Biology33 citations
Semantic Scholar
Real-world implementation of sequential targeted therapies for EGFR-mutated lung cancer
N. Magios, F. Bozorgmehr, Anna-Lena Volckmar, Daniel Kazdal +15 more
2021Therapeutic Advances in Medical Oncology32 citations Open access
Semantic Scholar
Identification of BCL-XL as highly active survival factor and promising therapeutic target in colorectal cancer
Anna-Lena Scherr, A. Mock, G. Gdynia, N. Schmitt +30 more
2020Cell Death and Disease32 citations Open access
Semantic Scholar
Assigning evidence to actionability: An introduction to variant interpretation in precision cancer medicine
P. Horák, J. Leichsenring, H. Goldschmid, S. Kreutzfeldt +20 more
2021Genes, Chromosomes and Cancer30 citations Open access
Semantic Scholar
HIF1α-mediated RelB/APOBEC3B downregulation allows Hepatitis B Virus persistence
T. Riedl, Suzanne Faure-Dupuy, M. Rolland, Svenja Schuehle +21 more
2021Hepatology30 citations Open access
Semantic Scholar
Prohibitin, STAT3 and SH2D4A physically and functionally interact in tumor cell mitochondria
C. Ploeger, Thorben Huth, Raisatun N. Sugiyanto, S. Pusch +7 more
2020Cell Death and Disease30 citations Open access
Semantic Scholar
NTRK testing: First results of the QuiP‐EQA scheme and a comprehensive map of NTRK fusion variants and their diagnostic coverage by targeted RNA‐based NGS assays
M. Kirchner, J. Glade, U. Lehmann, S. Merkelbach-Bruse +20 more
2020Genes, Chromosomes and Cancer28 citations Open access
Semantic Scholar
Programmed Death Ligand-1 (PD-L1) Is an Independent Negative Prognosticator in Western-World Gallbladder Cancer
T. Albrecht, Fritz Brinkmann, M. Albrecht, A. Lonsdorf +11 more
2021Cancers27 citations Open access
Semantic Scholar
Clinical Characteristics and Outcomes of Colorectal Cancer in the ColoCare Study: Differences by Age of Onset
C. Himbert, J. Figueiredo, D. Shibata, J. Ose +54 more
2021Cancers27 citations Open access
Semantic Scholar
High prevalence of DNA damage repair gene defects and TP53 alterations in men with treatment-naïve metastatic prostate cancer -Results from a prospective pilot study using a 37 gene panel.
Cathleen Nientiedt, V. Endris, M. Jenzer, J. Mansour +41 more
2020Urologic oncology25 citations Open access
Semantic Scholar
Mutations in TP53 or DNA damage repair genes define poor prognostic subgroups in primary prostate cancer.
Cathleen Nientiedt, J. Budczies, V. Endris, M. Kirchner +35 more
2021Urologic oncology23 citations Open access
Semantic Scholar
miRNA profiling of biliary intraepithelial neoplasia reveals stepwise tumorigenesis in distal cholangiocarcinoma via the miR‐451a/ATF2 axis
Moritz A. Loeffler, Jun Hu, M. Kirchner, Xi-Yang Wei +16 more
2020Journal of Pathology23 citations Open access
Semantic Scholar
KRAS/GNAS‐testing by highly sensitive deep targeted next generation sequencing improves the endoscopic ultrasound‐guided workup of suspected mucinous neoplasms of the pancreas
D. Schmitz, Daniel Kazdal, M. Allgäuer, M. Trunk +19 more
2021Genes, Chromosomes and Cancer22 citations
Semantic Scholar
HER2 testing in gastric cancer diagnosis: insights on variables influencing HER2-positivity from a large, multicenter, observational study in Germany
G. Baretton, H. Kreipe, P. Schirmacher, T. Gaiser +6 more
2019Virchows Archiv22 citations
Semantic Scholar
Knowledge bases and software support for variant interpretation in precision oncology
Florian Borchert, A. Mock, A. Tomczak, Jonas Hügel +13 more
2021Briefings Bioinform.21 citations Open access
Semantic Scholar
Circulating Folate and Folic Acid Concentrations: Associations With Colorectal Cancer Recurrence and Survival
Anne J. M. R. Geijsen, A. Ulvik, B. Gigic, Dieuwertje E. G. Kok +51 more
2020JNCI Cancer Spectrum21 citations Open access
Semantic Scholar
Mass Spectrometry Imaging for Reliable and Fast Classification of Non-Small Cell Lung Cancer Subtypes
M. Kriegsmann, C. Zgorzelski, R. Casadonte, K. Schwamborn +15 more
2020Cancers21 citations Open access
Semantic Scholar
Co-expression of YAP and TAZ associates with chromosomal instability in human cholangiocarcinoma
M. Tóth, L. Wehling, L. Thiess, F. Rose +17 more
2021BMC Cancer20 citations Open access
Semantic Scholar
Integrated clinicomolecular characterization identifies RAS activation and CDKN2A deletion as independent adverse prognostic factors in cancer of unknown primary
T. Bochtler, Anna Reiling, V. Endris, T. Hielscher +13 more
2020International Journal of Cancer20 citations Open access
Semantic Scholar
Multi-omics analysis reveals adipose-tumor crosstalk in colorectal cancer patients
A. Holowatyj, Mariam Haffa, Teng-Da Lin, D. Scherer +30 more
2020Cancer Prevention Research19 citations Open access
Semantic Scholar

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