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T. Bochtler · SciRah

Researcher profile · Semantic Scholar

T. Bochtler

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T. Bochtler — researcher profile on SciRah

h-index: 28
Works: 96
Citations: 2,890

Most-cited papers

Measurable residual disease-guided treatment with azacitidine to prevent haematological relapse in patients with myelodysplastic syndrome and acute myeloid leukaemia (RELAZA2): an open-label, multicentre, phase 2 trial.
U. Platzbecker, J. Middeke, K. Sockel, R. Herbst +27 more
2018The Lancet Oncology279 citations
Semantic Scholar
Immunohistochemistry in the classification of systemic forms of amyloidosis: a systematic investigation of 117 patients.
S. Schönland, U. Hegenbart, T. Bochtler, A. Mangatter +4 more
2012Blood239 citations Open access
Semantic Scholar
Translocation t(11;14) is associated with adverse outcome in patients with newly diagnosed AL amyloidosis when treated with bortezomib-based regimens.
T. Bochtler, U. Hegenbart, C. Kunz, M. Granzow +8 more
2015Journal of Clinical Oncology208 citations
Semantic Scholar
Cancer of unknown primary: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.
A. Krämer, T. Bochtler, C. Pauli, G. Baciarello +11 more
2022Annals of Oncology191 citations Open access
Semantic Scholar
RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML.
Anna L. Brown, P. Arts, C. Carmichael, M. Babic +55 more
2020Blood Advances138 citations Open access
Semantic Scholar
AL amyloidosis patients with low amyloidogenic free light chain levels at first diagnosis have an excellent prognosis.
Tobias Dittrich, T. Bochtler, Christoph Kimmich, N. Becker +5 more
2017Blood132 citations
Semantic Scholar
Evaluation of the cytogenetic aberration pattern in amyloid light chain amyloidosis as compared with monoclonal gammopathy of undetermined significance reveals common pathways of karyotypic instability.
T. Bochtler, U. Hegenbart, F. Cremer, C. Heiss +9 more
2008Blood114 citations Open access
Semantic Scholar
Gain of chromosome 1q21 is an independent adverse prognostic factor in light chain amyloidosis patients treated with melphalan/dexamethasone
T. Bochtler, U. Hegenbart, C. Kunz, A. Benner +9 more
2014Amyloid: Journal of Protein Folding Disorders89 citations
Semantic Scholar
Treatment with intravenous melphalan and dexamethasone is not able to overcome the poor prognosis of patients with newly diagnosed systemic light chain amyloidosis and severe cardiac involvement.
S. Dietrich, S. Schönland, A. Benner, T. Bochtler +7 more
2010Blood87 citations
Semantic Scholar
DNA Damage-Induced Accumulation of Centrosomal Chk1 Contributes to its Checkpoint Function
H. Löffler, T. Bochtler, B. Fritz, B. Tews +4 more
2007Cell Cycle85 citations Open access
Semantic Scholar
Allogeneic Stem Cell Transplantation Improves Survival in Patients with Acute Myeloid Leukemia Characterized by a High Allelic Ratio of Mutant FLT3-ITD.
A. Ho, J. Schetelig, T. Bochtler, M. Schaich +17 more
2016Biology of Blood and Marrow Transplantation81 citations Open access
Semantic Scholar
Prognostic impact of cytogenetic aberrations in AL amyloidosis patients after high-dose melphalan: a long-term follow-up study.
T. Bochtler, U. Hegenbart, C. Kunz, A. Benner +9 more
2016Blood78 citations
Semantic Scholar
Clonal heterogeneity as detected by metaphase karyotyping is an indicator of poor prognosis in acute myeloid leukemia.
T. Bochtler, F. Stölzel, C. Heilig, C. Kunz +10 more
2013Journal of Clinical Oncology71 citations
Semantic Scholar
Evaluation of the serum-free light chain test in untreated patients with AL amyloidosis
T. Bochtler, U. Hegenbart, C. Heiss, A. Benner +7 more
2008Haematologica70 citations Open access
Semantic Scholar
Outcome of patients with abnl(17p) acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation.
J. Middeke, M. Fang, J. Cornelissen, B. Mohr +15 more
2013Blood66 citations
Semantic Scholar
Hyperdiploidy is less frequent in AL amyloidosis compared with monoclonal gammopathy of undetermined significance and inversely associated with translocation t(11;14).
T. Bochtler, U. Hegenbart, C. Heiss, A. Benner +11 more
2011Blood66 citations Open access
Semantic Scholar
Marker chromosomes can arise from chromothripsis and predict adverse prognosis in acute myeloid leukemia.
T. Bochtler, M. Granzow, F. Stölzel, C. Kunz +15 more
2016Blood65 citations
Semantic Scholar
A Challenging Task: Identifying Patients with Cancer of Unknown Primary (CUP) According to ESMO Guidelines: The CUPISCO Trial Experience
C. Pauli, T. Bochtler, L. Mileshkin, G. Baciarello +12 more
2021The Oncologist62 citations Open access
Semantic Scholar
Diagnosis and management of metastatic neoplasms with unknown primary.
T. Bochtler, H. Löffler, A. Krämer
2018Seminars in diagnostic pathology57 citations
Semantic Scholar
Does Cancer of Unknown Primary (CUP) Truly Exist as a Distinct Cancer Entity?
T. Bochtler, A. Krämer
2019Frontiers in Oncology53 citations Open access
Semantic Scholar
RNA-Based Detection of Gene Fusions in Formalin-Fixed and Paraffin-Embedded Solid Cancer Samples
M. Kirchner, O. Neumann, Anna-Lena Volckmar, Fabian Stögbauer +15 more
2019Cancers46 citations Open access
Semantic Scholar
Performance analysis of AL amyloidosis cardiac biomarker staging systems with special focus on renal failure and atrial arrhythmia
Tobias Dittrich, A. Benner, Christoph Kimmich, Fabian Aus Dem Siepen +7 more
2019Haematologica42 citations Open access
Semantic Scholar
Lenalidomide/melphalan/dexamethasone in newly diagnosed patients with immunoglobulin light chain amyloidosis: results of a prospective phase 2 study with long-term follow up
U. Hegenbart, T. Bochtler, A. Benner, N. Becker +12 more
2017Haematologica41 citations Open access
Semantic Scholar
Reduced hematopoietic stem cell frequency predicts outcome in acute myeloid leukemia
Wenwen Wang, T. Stiehl, S. Raffel, Van T. Hoang +14 more
2017Haematologica39 citations Open access
Semantic Scholar
Treatment of AL amyloidosis with bendamustine: a study of 122 patients.
P. Milani, S. Schönland, G. Merlini, Christoph Kimmich +7 more
2018Blood34 citations Open access
Semantic Scholar
Fludarabine-treosulfan compared to thiotepa-busulfan-fludarabine or FLAMSA as conditioning regimen for patients with primary refractory or relapsed acute myeloid leukemia: a study from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation (EBMT)
F. Saraceni, M. Labopin, A. Brecht, N. Kroger +11 more
2019Journal of Hematology & Oncology33 citations Open access
Semantic Scholar
Cytogenetic intraclonal heterogeneity of plasma cell dyscrasia in AL amyloidosis as compared with multiple myeloma.
T. Bochtler, M. Merz, T. Hielscher, M. Granzow +13 more
2018Blood Advances33 citations Open access
Semantic Scholar
Micronucleus formation in human cancer cells is biased by chromosome size
T. Bochtler, Mutlu Kartal-Kaess, M. Granzow, T. Hielscher +4 more
2019Genes, Chromosomes and Cancer28 citations
Semantic Scholar
Phase I dose‐escalation trial investigating volasertib as monotherapy or in combination with cytarabine in patients with relapsed/refractory acute myeloid leukaemia
O. Ottmann, C. Müller-Tidow, A. Krämer, R. Schlenk +9 more
2018British Journal of Haematology28 citations Open access
Semantic Scholar
Prognostic significance of cytogenetic heterogeneity in patients with newly diagnosed multiple myeloma.
M. Merz, A. Jauch, T. Hielscher, T. Bochtler +15 more
2018Blood Advances28 citations Open access
Semantic Scholar
TP53 deficiency permits chromosome abnormalities and karyotype heterogeneity in acute myeloid leukemia
A. Cazzola, C. Schlegel, I. Jansen, T. Bochtler +2 more
2019Leukemia23 citations
Semantic Scholar
Comparative genetic profiling aids diagnosis and clinical decision making in challenging cases of CUP syndrome
T. Bochtler, V. Endris, J. Leichsenring, Anna Reiling +7 more
2019International Journal of Cancer23 citations Open access
Semantic Scholar
Pan-Mutant-IDH1 Inhibitor Bay-1436032 Is Highly Effective Against Human IDH1 Mutant Acute Myeloid Leukemia In Vivo
M. Heuser, Lena Herbst, S. Pusch, Lara C. Klett +25 more
201623 citations
Semantic Scholar
Integrated clinicomolecular characterization identifies RAS activation and CDKN2A deletion as independent adverse prognostic factors in cancer of unknown primary
T. Bochtler, Anna Reiling, V. Endris, T. Hielscher +13 more
2020International Journal of Cancer20 citations Open access
Semantic Scholar
Novel recurrent chromosomal aberrations detected in clonal plasma cells of light chain amyloidosis patients show potential adverse prognostic effect: first results from a genome-wide copy number array analysis
M. Granzow, U. Hegenbart, K. Hinderhofer, D. Hose +6 more
2017Haematologica19 citations Open access
Semantic Scholar
Targeting rare and non-canonical driver variants in NSCLC - An uncharted clinical field.
Anna-Lena Volckmar, P. Christopoulos, M. Kirchner, M. Allgäuer +24 more
2021Lung Cancer17 citations
Semantic Scholar
Local ablative treatment with surgery and/or radiotherapy in single-site and oligometastatic carcinoma of unknown primary.
M. Pouyiourou, Timothy Wohlfromm, B. Kraft, T. Hielscher +8 more
2021European Journal of Cancer16 citations
Semantic Scholar
Prognostic impact of copy number alterations and tumor mutational burden in carcinoma of unknown primary
T. Bochtler, Timothy Wohlfromm, T. Hielscher, D. Stichel +7 more
2022Genes, Chromosomes and Cancer12 citations Open access
Semantic Scholar
Hematological Malignancies in Adults With a Family Predisposition.
T. Bochtler, G. Haag, S. Schott, M. Kloor +2 more
2018Deutsches Ärzteblatt International12 citations Open access
Semantic Scholar
Mesenchymal stromal cells contribute to quiescence of therapy‐resistant leukemic cells in acute myeloid leukemia
Wenwen Wang, T. Bochtler, P. Wuchter, Linda Manta +4 more
2017European Journal of Haematology11 citations
Semantic Scholar
Azacitidine and low‐dose cytarabine in palliative patients with acute myeloid leukemia and high bone marrow blast counts – a retrospective single‐center experience
A. Radujkovic, S. Dietrich, T. Bochtler, A. Krämer +4 more
2014European Journal of Haematology10 citations
Semantic Scholar
Treatment of AL Amyloidosis with Bendamustine
G. Palladini, S. Schönland, P. Milani, Christoph Kimmich +4 more
201210 citations
Semantic Scholar
Response to bendamustine is associated with a survival advantage in a heavily pretreated patients with AL amyloidosis
P. Milani, S. Schönland, G. Palladini, Christoph Kimmich +8 more
2017Amyloid: Journal of Protein Folding Disorders9 citations
Semantic Scholar
Cancer-of-Unknown-Primary-Origin: A SEER–Medicare Study of Patterns of Care and Outcomes among Elderly Patients in Clinical Practice
L. Mileshkin, T. Bochtler, G. Gatta, R. Kurzrock +7 more
2022Cancers8 citations Open access
Semantic Scholar
Integrated Histogenetic Analysis Reveals BAP1-Mutated Epithelioid Mesothelioma in a Patient With Cancer of Unknown Primary.
T. Bochtler, V. Endris, Anna Reiling, J. Leichsenring +7 more
2018The Journal of the National Comprehensive Cancer Network8 citations Open access
Semantic Scholar
Minimal-Residual Disease Guided Treatment with Azacitidine in MDS/AML Patients at Imminent Risk of Relapse: Results of the Prospective RELAZA2 Trial
U. Platzbecker, J. Middeke, K. Sockel, Anke Mütherig +23 more
20178 citations
Semantic Scholar
Chronic lymphocytic leukaemia and concomitant relapsing polychondritis: a report on one treatment for the combined manifestation of two diseases.
T. Bochtler, M. Hensel, H. Lorenz, A. Ho +1 more
2005Rheumatology8 citations Open access
Semantic Scholar
Azacitidine for Pre-Emptive Treatment of Measurable-Residual Disease in MDS/AML Patients at High Risk of Hematological Relapse: Results of the Second Cohort of the RELAZA2 Trial
U. Platzbecker, J. Middeke, K. Sockel, R. Herbst +28 more
2019Blood6 citations Open access
Semantic Scholar
Single Center Experience of Lenalidomide/Dexamethasone Treatment in 40 Patients with Light Chain Amyloidosis: High Toxicity in Patients with Severe Impaired Renal and Cardiac Function.
S. Schoenland, T. Bochtler, S. Dietrich, Ulrike Klein +3 more
20086 citations
Semantic Scholar
Improvement of Long-Term Survival after High-Dose Melphalan in Patients with Light Chain Amyloidosis Responding to Induction Chemotherapy.
A. Mangatter, S. Schoenland, Marion Hansberg, T. Bochtler +6 more
20086 citations
Semantic Scholar

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A. Ho×20
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U. Hegenbart×19
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S. Schönland×17
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