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M. Shuler · SciRah

Researcher profile · Semantic Scholar

M. Shuler

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M. Shuler — researcher profile on SciRah

h-index: 70
Works: 320
Citations: 21K

Most-cited papers

TEER measurement techniques for in vitro barrier model systems
B. Srinivasan, A. Kolli, M. Esch, H. Abaci +2 more
2015Journal of laboratory automation1,981 citations Open access
Semantic Scholar
A guide to the organ-on-a-chip
C. Leung, P. de Haan, Kacey Ronaldson-Bouchard, Ge-Ah Kim +11 more
2022Nature Reviews Methods Primers964 citations Open access
Semantic Scholar
A microfluidic device for a pharmacokinetic-pharmacodynamic (PK-PD) model on a chip.
J. Sung, C. Kam, M. Shuler
2010Lab on a Chip478 citations
Semantic Scholar
Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs
C. Oleaga, C. Bernabini, Alec S. T. Smith, B. Srinivasan +19 more
2016Scientific Reports393 citations Open access
Semantic Scholar
The role of body-on-a-chip devices in drug and toxicity studies.
M. Esch, T. L. King, M. Shuler
2011Annual Review of Biomedical Engineering326 citations
Semantic Scholar
Oral exposure to polystyrene nanoparticles affects iron absorption.
Gretchen J. Mahler, M. Esch, E. Tako, T. Southard +3 more
2012Nature Nanotechnology322 citations
Semantic Scholar
Microscale 3-D hydrogel scaffold for biomimetic gastrointestinal (GI) tract model.
J. Sung, Jia-Jie Yu, Dan Luo, M. Shuler +1 more
2011Lab on a Chip305 citations
Semantic Scholar
Microfabricated Mammalian Organ Systems and Their Integration into Models of Whole Animals and Humans
J. Sung, M. Esch, J. Prot, Christopher J. Long +3 more
2013Lab on a Chip232 citations Open access
Semantic Scholar
Body-on-a-Chip Simulation with Gastrointestinal Tract and Liver Tissues Suggests that Ingested Nanoparticles Have the Potential to Cause Liver Injury
M. Esch, Gretchen J. Mahler, T. Stokol, M. Shuler
2014Lab on a Chip227 citations Open access
Semantic Scholar
Recent advances in body-on-a-chip systems
J. Sung, Ying I. Wang, N. Sriram, Max Jackson +3 more
2018Analytical Chemistry214 citations Open access
Semantic Scholar
Pumpless microfluidic platform for drug testing on human skin equivalents
H. Abaci, K. Gledhill, Zong-You Guo, A. Christiano +1 more
2015Lab on a Chip212 citations Open access
Semantic Scholar
Human-on-a-chip design strategies and principles for physiologically based pharmocokinetics/pharmacodynamics modeling
H. Abaci, M. Shuler
2015Integrative Biology198 citations Open access
Semantic Scholar
A physical sciences network characterization of non-tumorigenic and metastatic cells
D. Agus, J. Alexander, W. Arap, S. Ashili +91 more
2013Scientific Reports182 citations Open access
Semantic Scholar
Modular, pumpless body-on-a-chip platform for the co-culture of GI tract epithelium and 3D primary liver tissue.
M. Esch, Hidetaka Ueno, Dawn R. Applegate, M. Shuler
2016Lab on a Chip180 citations
Semantic Scholar
Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics
C. McAleer, Christopher J. Long, Daniel H. Elbrecht, Trevor Sasserath +10 more
2019Science Translational Medicine174 citations Open access
Semantic Scholar
On chip porous polymer membranes for integration of gastrointestinal tract epithelium with microfluidic ‘body-on-a-chip’ devices
M. Esch, J. Sung, Jennifer Yang, Changhao Yu +3 more
2012Biomedical microdevices169 citations
Semantic Scholar
How Multi-Organ Microdevices Can Help Foster Drug Development
M. Esch, Alec S. T. Smith, J. Prot, C. Oleaga +2 more
2014Advanced Drug Delivery Reviews148 citations Open access
Semantic Scholar
Multi-Cellular 3D Human Primary Liver Cell Cultures Elevate Metabolic Activity Under Fluidic Flow
M. Esch, J. Prot, Ying I. Wang, P. Miller +4 more
2015Lab on a Chip146 citations Open access
Semantic Scholar
Fabrication and optimization of alginate hydrogel constructs for use in 3D neural cell culture
J. Frampton, M. Hynd, M. Shuler, W. Shain
2011Biomedical Materials144 citations Open access
Semantic Scholar
Multi-Organ Microphysiological Systems for Drug Development: Strategies, Advances and Challenges
Ying I. Wang, C. Carmona, J. Hickman, M. Shuler
2017Advanced Healthcare Materials141 citations Open access
Semantic Scholar
Using PBPK guided “Body-on-a-Chip” Systems to Predict Mammalian Response to Drug and Chemical Exposure
J. Sung, B. Srinivasan, M. Esch, W. Mclamb +3 more
2014Experimental biology and medicine124 citations Open access
Semantic Scholar
Modeling Barrier Tissues In Vitro: Methods, Achievements, and Challenges
Courtney M. Sakolish, M. Esch, J. Hickman, M. Shuler +1 more
2016EBioMedicine123 citations Open access
Semantic Scholar
UniChip enables long-term recirculating unidirectional perfusion with gravity-driven flow for microphysiological systems
Ying I. Wang, M. Shuler
2018Lab on a Chip98 citations Open access
Semantic Scholar
A recellularized human colon model identifies cancer driver genes
H. Chen, Zhubo Wei, Jian Sun, Asmita Bhattacharya +14 more
2016Nature Biotechnology93 citations Open access
Semantic Scholar
On the potential of in vitro organ-chip models to define temporal pharmacokinetic-pharmacodynamic relationships
C. McAleer, A. Pointon, Christopher J. Long, Rocky L. Brighton +14 more
2019Scientific Reports88 citations Open access
Semantic Scholar
In vitro microscale systems for systematic drug toxicity study
J. Sung, M. Shuler
2010Bioprocess and biosystems engineering (Print)86 citations
Semantic Scholar
New approach methodologies (NAMs) for human-relevant biokinetics predictions: Meeting the paradigm shift in toxicology towards an animal-free chemical risk assessment.
A. Punt, H. Bouwmeester, B. Blaauboer, S. Coecke +19 more
2020ALTEX85 citations Open access
Semantic Scholar
A Pumpless Body-on-a-chip Model Using a Primary Culture of human Intestinal Cells and a 3D Culture of Liver Cells
H. Chen, P. Miller, M. Shuler
2018Lab on a Chip85 citations Open access
Semantic Scholar
Differential Monocyte Actuation in a Three‐Organ Functional Innate Immune System‐on‐a‐Chip
Trevor Sasserath, J. Rumsey, C. McAleer, L. R. Bridges +7 more
2020Advancement of science77 citations Open access
Semantic Scholar
Characterization of In Vitro Endothelial Linings Grown Within Microfluidic Channels
M. Esch, D. J. Post, M. Shuler, T. Stokol
2011Tissue Engineering. Part A76 citations Open access
Semantic Scholar
Murine in vitro model of the blood-brain barrier for evaluating drug transport.
Gilda Shayan, Yong-Seok Choi, Eric V. Shusta, M. Shuler +1 more
2011European Journal of Pharmaceutical Sciences72 citations
Semantic Scholar
Microtechnology for Mimicking In Vivo Tissue Environment
J. Sung, M. Shuler
2012Annals of Biomedical Engineering65 citations
Semantic Scholar
Integration of in silico and in vitro platforms for pharmacokinetic–pharmacodynamic modeling
J. Sung, M. Esch, M. Shuler
2010Expert Opinion on Drug Metabolism & Toxicology62 citations
Semantic Scholar
Validation of an adipose-liver human-on-a-chip model of NAFLD for preclinical therapeutic efficacy evaluation
Victoria L. Slaughter, J. Rumsey, Rachel E Boone, D. Malik +7 more
2021Scientific Reports58 citations Open access
Semantic Scholar
Self-contained, low-cost Body-on-a-Chip systems for drug development
Ying I. Wang, C. Oleaga, Christopher J. Long, M. Esch +4 more
2017Experimental biology and medicine56 citations Open access
Semantic Scholar
Strategies for using mathematical modeling approaches to design and interpret multi-organ microphysiological systems (MPS)
J. Sung, Ying I. Wang, M. Shuler
2019APL Bioengineering54 citations Open access
Semantic Scholar
Microfluidic-Based Cell-Embedded Microgels Using Nonfluorinated Oil as a Model for the Gastrointestinal Niche.
Seyedramin Pajoumshariati, M. Azizi, D. Wesner, P. Miller +2 more
2018ACS Applied Materials and Interfaces45 citations
Semantic Scholar
Organ-, body- and disease-on-a-chip systems.
M. Shuler
2017Lab on a Chip44 citations
Semantic Scholar
Biotechnology and Bioengineering
P. Miller, Ying I. Wang, Emily Gao, M. Shuler
201936 citations
Semantic Scholar
Toward in vitro models of brain structure and function
M. Shuler, J. Hickman
2014Proceedings of the National Academy of Sciences of the United States of America34 citations Open access
Semantic Scholar
Peer Review #2 of "A high Mn(II)-tolerance strain, Bacillus thuringiensis HM7, isolated from manganese ore and its biosorption characteristics (v0.1)"
Hui-Min Huang, Yun-Lin Zhao, Zheng-Gang Xu, Yi Ding +363 more
202031 citations Open access
Semantic Scholar
Modeling a minimal cell.
M. Shuler, P. Foley, Jordan C. Atlas
2012Methods in molecular biology30 citations
Semantic Scholar
Microphysiological systems and low-cost microfluidic platform with analytics
Alec st Smith, Christopher J. Long, Bonnie J. Berry, C. McAleer +7 more
2013Stem cell research & therapeutics28 citations Open access
Semantic Scholar
Mimicking the Human Physiology with Microphysiological Systems (MPS)
J. Sung, Jamin Koo, M. Shuler
2019BioChip Journal27 citations Open access
Semantic Scholar
Chemokine-Targeted Mouse Models of Human Primary and Metastatic Colorectal Cancer
H. Chen, Jian Sun, Zhi-Liang Huang, Harry Hou +24 more
2015Nature Biotechnology25 citations Open access
Semantic Scholar
Metacridamides A and B, macrocycles from conidia of the entomopathogenic fungus Metarhizium acridum
S. Krasnoff, U. Englich, P. Miller, M. Shuler +3 more
2012Journal of Natural Products24 citations Open access
Semantic Scholar
A Functional Human-on-a-Chip Autoimmune Disease Model of Myasthenia Gravis for Development of Therapeutics
V. Smith, Huan Nguyen, J. Rumsey, Christopher J. Long +2 more
2021Frontiers in Cell and Developmental Biology22 citations Open access
Semantic Scholar
Promises, challenges and future directions of microCCAs.
M. Esch, J. Sung, M. Shuler
2010Journal of Biotechnology22 citations
Semantic Scholar
Pumpless, unidirectional microphysiological system for testing metabolism‐dependent chemotherapeutic toxicity
Danielle J. LaValley, P. Miller, M. Shuler
2020Biotechnology progress (Print)19 citations
Semantic Scholar
Development of disposable PDMS micro cell culture analog devices with photopolymerizable hydrogel encapsulating living cells
Hui Xu, J. Wu, Chih-Chang Chu, M. Shuler
2011Biomedical microdevices18 citations
Semantic Scholar

Frequent co-authors

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M. Esch×17
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M. Esch — researcher profile on SciRah
J. Hickman×15
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J. Sung×12
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Christopher J. Long×9
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Ying I. Wang — researcher profile on SciRah

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P. Miller — researcher profile on SciRah

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C. McAleer — researcher profile on SciRah

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J. Prot — researcher profile on SciRah

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B. Srinivasan — researcher profile on SciRah

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H. Abaci — researcher profile on SciRah

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C. Oleaga — researcher profile on SciRah