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W. Arap · SciRah

Researcher profile · Semantic Scholar

W. Arap

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W. Arap — researcher profile on SciRah

h-index: 75
Works: 360
Citations: 25K

Most-cited papers

Preclinical efficacy of the first-in-class GPER-selective agonist G-1 in mouse models of obesity and diabetes
Geetanjali Sharma, Chelin Hu, Daniela I. Staquicini, J. Brigman +7 more
2020Science Translational Medicine93 citations Open access
Semantic Scholar
Fatty acid mobilization from adipose tissue is mediated by CD36 posttranslational modifications and intracellular trafficking
Alexes C. Daquinag, Zhanguo Gao, Cale Fussell, Linnet Immaraj +5 more
2021JCI Insight84 citations Open access
Semantic Scholar
Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22
A. Giannou, Jan Kempski, A. Shiri, J. Lücke +71 more
2023Immunity60 citations Open access
Semantic Scholar
Mathematical modeling of cancer immunotherapy for personalized clinical translation
J. D. Butner, Prashant Dogra, Caroline Chung, R. Pasqualini +4 more
2022Nature Computational Science57 citations Open access
Semantic Scholar
Emerging Pharmacologic Targets in Cerebral Cavernous Malformation and Potential Strategies to Alter the Natural History of a Difficult Disease: A Review
M. O. Chohan, Serena Marchiò, L. Morrison, R. Sidman +5 more
2019JAMA Neurology55 citations
Semantic Scholar
Mathematical prediction of clinical outcomes in advanced cancer patients treated with checkpoint inhibitor immunotherapy
J. D. Butner, D. Elganainy, Charles X. Wang, Zhi-Hui Wang +8 more
2020Science Advances54 citations Open access
Semantic Scholar
A total transcriptome profiling method for plasma-derived extracellular vesicles: applications for liquid biopsies
M. Amorim, R. Valieris, R. Drummond, Melissa P. Pizzi +8 more
2017Scientific Reports54 citations Open access
Semantic Scholar
Design and proof of concept for targeted phage-based COVID-19 vaccination strategies with a streamlined cold-free supply chain
Daniela I. Staquicini, F. Tang, Christopher Markosian, Virginia J. Yao +17 more
2021Proceedings of the National Academy of Sciences of the United States of America51 citations Open access
Semantic Scholar
Intracellular targeting of annexin A2 inhibits tumor cell adhesion, migration, and in vivo grafting
Daniela I. Staquicini, Roberto Rangel, L. Guzman-Rojas, F. Staquicini +10 more
2017Scientific Reports49 citations Open access
Semantic Scholar
Anti-GRP78 autoantibodies induce endothelial cell activation and accelerate the development of atherosclerotic lesions.
E. Crane, Ali A. Al-Hashimi, Jack Chen, E. Lynn +13 more
2018JCI Insight47 citations Open access
Semantic Scholar
Self-targeting of TNF-releasing cancer cells in preclinical models of primary and metastatic tumors
Eleonora Dondossola, A. Dobroff, Serena Marchiò, M. Cardó-Vila +6 more
2016Proceedings of the National Academy of Sciences of the United States of America44 citations Open access
Semantic Scholar
Innate Immunity Plays a Key Role in Controlling Viral Load in COVID-19: Mechanistic Insights from a Whole-Body Infection Dynamics Model
Prashant Dogra, J. Ruiz-Ramírez, K. Sinha, J. D. Butner +8 more
2020medRxiv42 citations Open access
Semantic Scholar
Next-generation of targeted AAVP vectors for systemic transgene delivery against cancer
K. Suwan, Teerapong Yata, Sajee Waramit, J. Przystal +13 more
2019Proceedings of the National Academy of Sciences of the United States of America41 citations Open access
Semantic Scholar
BMTP-11 is active in preclinical models of human osteosarcoma and a candidate targeted drug for clinical translation
Valerae O. Lewis, Eswaran Devarajan, M. Cardó-Vila, Dafydd Thomas +5 more
2017Proceedings of the National Academy of Sciences of the United States of America38 citations Open access
Semantic Scholar
Monoclonal IgG in MGUS and multiple myeloma targets infectious pathogens.
A. Bosseboeuf, Delphine Féron, A. Tallet, C. Rossi +16 more
2017JCI Insight38 citations Open access
Semantic Scholar
The loss-of-function PCSK9Q152H variant increases ER chaperones GRP78 and GRP94 and protects against liver injury.
P. Lebeau, H. Wassef, J. Byun, Khrystyna Platko +16 more
2020Journal of Clinical Investigation36 citations Open access
Semantic Scholar
Targeted AAVP-based therapy in a mouse model of human glioblastoma: A comparison of cytotoxic versus suicide gene delivery strategies
F. Staquicini, Tracey L. Smith, F. Tang, J. Gelovani +6 more
2019Cancer Gene Therapy36 citations Open access
Semantic Scholar
Interaction between tumor cell surface receptor RAGE and proteinase 3 mediates prostate cancer metastasis to bone
Mikhail G. Kolonin, Anna Sergeeva, Daniela I. Staquicini, Tracey L. Smith +6 more
2017Cancer Research35 citations Open access
Semantic Scholar
TLR9/MyD88/TRIF signaling activates host immune inhibitory CD200 in Leishmania infection.
I. Sauter, Katerine G. Madrid, J. B. de Assis, A. Sá-Nunes +5 more
2019JCI Insight31 citations Open access
Semantic Scholar
Therapeutic targeting of membrane-associated GRP78 in leukemia and lymphoma: preclinical efficacy in vitro and formal toxicity study of BMTP-78 in rodents and primates
Daniela I. Staquicini, S. D'Angelo, F. Ferrara, Katja Karjalainen +16 more
2017The Pharmacogenomics Journal30 citations Open access
Semantic Scholar
Targeting a cell surface vitamin D receptor on tumor-associated macrophages in triple-negative breast cancer
F. Staquicini, A. Hajitou, W. Driessen, Bettina Proneth +26 more
2021eLife29 citations Open access
Semantic Scholar
Targeted Phage Display-based Pulmonary Vaccination in Mice and Non-human Primates
Daniela I. Staquicini, E. Barbu, R. Zemans, B. Dray +17 more
2020i Medicina28 citations Open access
Semantic Scholar
Rational Design of Safer Inorganic Nanoparticles via Mechanistic Modeling-Informed Machine Learning
Joseph Cave, Anne Christiono, Carmine Schiavone, H. Pownall +10 more
2025ACS Nano27 citations Open access
Semantic Scholar
Ceramide launches an acute anti-adhesion pro-migration cell signaling program in response to chemotherapy
D. Canals, Silvia Salamone, B. Santacreu, Erika Nemeth +9 more
2020The FASEB Journal27 citations Open access
Semantic Scholar
Translational Modeling Identifies Synergy between Nanoparticle-Delivered miRNA-22 and Standard-of-Care Drugs in Triple-Negative Breast Cancer
Prashant Dogra, J. R. Ramírez, J. D. Butner, M. Peláez +8 more
2021Pharmaceutical Research25 citations Open access
Semantic Scholar
Predicting Proteome-Scale Protein Structure with Artificial Intelligence.
S. Burley, W. Arap, R. Pasqualini
2021New England Journal of Medicine24 citations
Semantic Scholar
A Mathematical Model to Estimate Chemotherapy Concentration at the Tumor-Site and Predict Therapy Response in Colorectal Cancer Patients with Liver Metastases
D. Anaya, Prashant Dogra, Zhi-Hui Wang, M. Haider +16 more
2020Cancers23 citations Open access
Semantic Scholar
Biobehavioral effects of Tai Chi Qigong in men with prostate cancer: Study design of a three-arm randomized clinical trial
Anita Y. Kinney, Cindy K. Blair, D. Guest, J. Ani +12 more
2019Contemporary Clinical Trials Communications21 citations Open access
Semantic Scholar
Autoantibodies against the cell surface–associated chaperone GRP78 stimulate tumor growth via tissue factor
Ali A. Al-Hashimi, P. Lebeau, Fadwa Majeed, Enio Polena +16 more
2017Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Integrated metabolic and genetic analysis reveals distinct features of human differentiated thyroid cancer
Eduardo Cararo Lopes, Akshada Sawant, D. Moore, Hua Ke +19 more
2023Clinical and Translational Medicine20 citations Open access
Semantic Scholar
Structural models of SARS-CoV-2 Omicron variant in complex with ACE2 receptor or antibodies suggest altered binding interfaces
Joseph H. Lubin, Christopher Markosian, D. Balamurugan, R. Pasqualini +3 more
2021bioRxiv20 citations Open access
Semantic Scholar
A modeling-based approach to optimize COVID-19 vaccine dosing schedules for improved protection
Prashant Dogra, Carmine Schiavone, Zhi-Hui Wang, J. Ruiz-Ramírez +8 more
2022medRxiv19 citations Open access
Semantic Scholar
Predicting breast cancer response to neoadjuvant chemotherapy based on tumor vascular features in needle biopsies.
Terisse A. Brocato, U. Brown-Glaberman, Zhi-Hui Wang, R. Selwyn +9 more
2019JCI Insight19 citations Open access
Semantic Scholar
Selection of phage-displayed accessible recombinant targeted antibodies (SPARTA): methodology and applications.
S. D'Angelo, F. Staquicini, F. Ferrara, Daniela I. Staquicini +8 more
2018JCI Insight18 citations Open access
Semantic Scholar
Genomic landscape of lymphatic malformations: a case series and response to the PI3Kα inhibitor alpelisib in an N-of-1 clinical trial
M. Shaheen, J. Tse, E. Sokol, M. Masterson +15 more
2022eLife17 citations Open access
Semantic Scholar
Early prediction of clinical response to checkpoint inhibitor therapy in human solid tumors through mathematical modeling
J. D. Butner, Geoffrey V. Martin, Zhi-Hui Wang, B. Corradetti +17 more
2021medRxiv15 citations Open access
Semantic Scholar
Repurposing Ferumoxytol as a Breast Cancer-Associated Macrophage Tracer with Five-Dimensional Quantitative [Fe]MRI of SPION Dynamics
L. Sillerud, A. Neuwelt, F. Staquicini, W. Arap +1 more
2021Cancers15 citations Open access
Semantic Scholar
Nna1 gene deficiency triggers Purkinje neuron death by tubulin hyperglutamylation and ER dysfunction
Jianxue Li, E. Snyder, F. Tang, R. Pasqualini +2 more
2020JCI Insight15 citations Open access
Semantic Scholar
Design and proof-of-concept for targeted phage-based COVID-19 vaccination strategies with a streamlined cold-free supply chain
Daniela I. Staquicini, F. Tang, Christopher Markosian, Virginia J. Yao +17 more
2021bioRxiv14 citations Open access
Semantic Scholar
Does the RAAS play a role in loss of taste and smell during COVID-19 infections?
Heloise R Luchiari, R. Giordano, R. Sidman, R. Pasqualini +1 more
2020The Pharmacogenomics Journal14 citations Open access
Semantic Scholar
A ligand motif enables differential vascular targeting of endothelial junctions between brain and retina
F. Tang, F. Staquicini, A. A. Teixeira, Jussara S Michaloski +8 more
2019Proceedings of the National Academy of Sciences of the United States of America14 citations Open access
Semantic Scholar
MLH1-rheMac hereditary nonpolyposis colorectal cancer syndrome in rhesus macaques
D. Brammer, P. Gillespie, M. Tian, Daniel Young +17 more
2018Proceedings of the National Academy of Sciences of the United States of America12 citations Open access
Semantic Scholar
Research involving the recently deceased: ethics questions that must be answered
Brendan Parent, O. Kates, W. Arap, Arthur Caplan +11 more
2023Journal of Medical Ethics11 citations
Semantic Scholar
Ceramide as an endothelial cell surface receptor and a lung-specific lipid vascular target for circulating ligands
Daniela I. Staquicini, M. Cardó-Vila, Jimmy A. Rotolo, F. Staquicini +25 more
2023Proceedings of the National Academy of Sciences of the United States of America11 citations Open access
Semantic Scholar
A refined genome phage display methodology delineates the human antibody response in patients with Chagas disease
A. A. Teixeira, L. A. Carnero, A. Kuramoto, F. Tang +13 more
2021iScience11 citations Open access
Semantic Scholar
The epigenetic reader PHF21B modulates murine social memory and synaptic plasticity–related genes
E. Chin, Q. Ma, Hongyu Ruan, Camille Chin +12 more
2022JCI Insight10 citations Open access
Semantic Scholar
Amphibian regeneration and mammalian cancer: Similarities and contrasts from an evolutionary biology perspective
B. Corradetti, Prashant Dogra, S. Pisano, Zhi-Hui Wang +6 more
2021Bioessays10 citations
Semantic Scholar
Generative artificial intelligence performs rudimentary structural biology modeling
Alexander M. Ille, Christopher Markosian, Stephen K. Burley, Michael B. Mathews +2 more
2024bioRxiv9 citations Open access
Semantic Scholar
Spatial and temporal dynamics of HDACs class IIa following mild traumatic brain injury in adult rats
Swatabdi Kamal, Shreya Potukutchi, David J. Gelovani, Robin E Bonomi +10 more
2022Molecular Psychiatry9 citations
Semantic Scholar
Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses
A. A. Teixeira, Serena Marchiò, E. Dias-Neto, D. Nunes +10 more
2017EMBO Molecular Medicine9 citations Open access
Semantic Scholar

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