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Eric V. Shusta · SciRah

Researcher profile · Semantic Scholar

Eric V. Shusta

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Eric V. Shusta — researcher profile on SciRah

h-index: 50
Works: 151
Citations: 10K

Most-cited papers

In vitro models of the blood–brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use
H. C. Helms, N. Abbott, M. Burek, R. Cecchelli +10 more
2016Journal of Cerebral Blood Flow and Metabolism655 citations Open access
Semantic Scholar
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies
Tae-Eun Park, Nur Mustafaoğlu, A. Herland, Ryan Hasselkus +13 more
2019Nature Communications515 citations Open access
Semantic Scholar
A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources
E. Lippmann, A. Al-Ahmad, S. Azarin, S. Palecek +1 more
2014Scientific Reports455 citations Open access
Semantic Scholar
Targeting receptor-mediated transport for delivery of biologics across the blood-brain barrier
J. Lajoie, Eric V. Shusta
2014Annual Review of Pharmacology and Toxicology366 citations Open access
Semantic Scholar
Efficient Differentiation of Human Pluripotent Stem Cells to Endothelial Progenitors via Small-Molecule Activation of WNT Signaling
Xiaojun Lian, Xiaoping Bao, A. Al-Ahmad, Jia-lu Liu +5 more
2014Stem Cell Reports302 citations Open access
Semantic Scholar
An Isogenic Blood-Brain Barrier Model Comprising Brain Endothelial Cells, Astrocytes and Neurons Derived from Human Induced Pluripotent Stem Cells
S. Canfield, Matthew J. Stebbins, Bethsymarie Soto Morales, Shusaku W. Asai +4 more
2017Journal of Neurochemistry223 citations Open access
Semantic Scholar
Directed differentiation of human pluripotent stem cells to blood-brain barrier endothelial cells
Tongcheng Qian, S. Maguire, S. Canfield, Xiaoping Bao +3 more
2017Science Advances212 citations Open access
Semantic Scholar
Modeling Psychomotor Retardation using iPSCs from MCT8-Deficient Patients Indicates a Prominent Role for the Blood-Brain Barrier
G. Vatine, A. Al-Ahmad, Bianca K. Barriga, Soshana P. Svendsen +16 more
2017Cell Stem Cell208 citations Open access
Semantic Scholar
Human pluripotent stem cell–derived brain pericyte–like cells induce blood-brain barrier properties
Matthew J. Stebbins, Benjamin D. Gastfriend, S. Canfield, Ming-Song Lee +6 more
2018Science Advances170 citations Open access
Semantic Scholar
Differentiation and Characterization of Human Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells
Matthew J. Stebbins, H. Wilson, S. Canfield, Tongcheng Qian +2 more
2015Methods153 citations Open access
Semantic Scholar
Neuronal Activity Regulates Blood-Brain Barrier Efflux Transport through Endothelial Circadian Genes
R. S. Pulido, Roeben N. Munji, Tamara C. Chan, Clare R. Quirk +15 more
2020Neuron142 citations Open access
Semantic Scholar
Transcriptomic comparison of human and mouse brain microvessels
Hannah W. Song, Koji L. Foreman, Benjamin D. Gastfriend, John S. Kuo +2 more
2020Scientific Reports141 citations Open access
Semantic Scholar
A human three-dimensional neural-perivascular ‘assembloid’ promotes astrocytic development and enables modeling of SARS-CoV-2 neuropathology
Lu Wang, David Sievert, A. Clark, Sangmoon Lee +6 more
2021Nature Medicine134 citations Open access
Semantic Scholar
Modeling the blood-brain barrier: Beyond the endothelial cells
Benjamin D. Gastfriend, S. Palecek, Eric V. Shusta
2018Current Opinion in Biomedical Engineering116 citations Open access
Semantic Scholar
Intrinsic blood-brain barrier dysfunction contributes to multiple sclerosis pathogenesis.
Hideaki Nishihara, Sylvain Perriot, Benjamin D. Gastfriend, Marel Steinfort +9 more
2022Brain : a journal of neurology109 citations Open access
Semantic Scholar
Exploring the effects of cell seeding density on the differentiation of human pluripotent stem cells to brain microvascular endothelial cells
H. Wilson, S. Canfield, M. Hjortness, S. Palecek +1 more
2015Fluids and Barriers of the CNS100 citations Open access
Semantic Scholar
An isogenic neurovascular unit model comprised of human induced pluripotent stem cell-derived brain microvascular endothelial cells, pericytes, astrocytes, and neurons
S. Canfield, Matthew J. Stebbins, Madeline G Faubion, Benjamin D. Gastfriend +2 more
2019Fluids and Barriers of the CNS92 citations Open access
Semantic Scholar
Blood–Brain Barrier Modulation to Improve Glioma Drug Delivery
Hui-Long Luo, Eric V. Shusta
2020Pharmaceutics88 citations Open access
Semantic Scholar
Commentary on human pluripotent stem cell-based blood–brain barrier models
E. Lippmann, S. Azarin, S. Palecek, Eric V. Shusta
2020Fluids and Barriers of the CNS87 citations Open access
Semantic Scholar
Advancing human induced pluripotent stem cell-derived blood-brain barrier models for studying immune cell interactions
Hideaki Nishihara, Benjamin D. Gastfriend, Sasha Soldati, Sylvain Perriot +9 more
2020The FASEB Journal72 citations Open access
Semantic Scholar
Wnt signaling mediates acquisition of blood–brain barrier properties in naïve endothelium derived from human pluripotent stem cells
Benjamin D. Gastfriend, Hideaki Nishihara, S. Canfield, Koji L. Foreman +3 more
2021bioRxiv61 citations Open access
Semantic Scholar
Regionally specified human pluripotent stem cell-derived astrocytes exhibit different molecular signatures and functional properties
Robert A Bradley, Jack M. Shireman, Caya McFalls, Jeea Choi +11 more
2019Development59 citations Open access
Semantic Scholar
Exploiting BBB Disruption for the Delivery of Nanocarriers to the Diseased CNS
Benjamin J. Umlauf, Eric V. Shusta
2019Current Opinion in Biotechnology57 citations Open access
Semantic Scholar
Protein engineering approaches for regulating blood-brain barrier transcytosis.
L. I. Goulatis, Eric V. Shusta
2017Current Opinion in Structural Biology57 citations Open access
Semantic Scholar
Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells as a Cellular Model to Study Neisseria meningitidis Infection
Sara F. Martins Gomes, A. Westermann, Till Sauerwein, T. Hertlein +7 more
2019Frontiers in Microbiology51 citations Open access
Semantic Scholar
Modeling Group B Streptococcus and Blood-Brain Barrier Interaction by Using Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells
Brandon J. Kim, Olivia B. Bee, Maura A. McDonagh, Matthew J. Stebbins +3 more
2017Msphere50 citations Open access
Semantic Scholar
Hyaluronan impairs the barrier integrity of brain microvascular endothelial cells through a CD44-dependent pathway
A. Al-Ahmad, Ronak Patel, S. Palecek, Eric V. Shusta
2019Journal of Cerebral Blood Flow and Metabolism48 citations Open access
Semantic Scholar
Activation of RARα, RARγ, or RXRα increases barrier tightness in human induced pluripotent stem cell-derived brain endothelial cells
Matthew J. Stebbins, E. Lippmann, Madeline G Faubion, R. Daneman +2 more
2017Biotechnology Journal42 citations Open access
Semantic Scholar
Efficient Differentiation of Human Pluripotent Stem Cells to Endothelial Progenitors via Small-Molecule Activation of WNT Signaling
X. Lian, Xiaoping Bao, A. Al-Ahmad, Jia-lu Liu +5 more
2015Stem Cell Reports36 citations Open access
Semantic Scholar
Analysis of Cancer-targeting Alkylphosphocholine Analog Permeability Characteristics Using a Human Induced Pluripotent Stem Cell Blood-Brain Barrier Model
P. Clark, A. Al-Ahmad, Tongcheng Qian, Ray R. Zhang +5 more
2016Molecular Pharmaceutics33 citations Open access
Semantic Scholar
In vitro Models of the Blood-Brain Barrier: Building in physiological complexity
Moriah E Katt, Eric V. Shusta
2020Current Opinion in Chemical Engineering32 citations Open access
Semantic Scholar
Directed Differentiation of Human Pluripotent Stem Cells to Podocytes under Defined Conditions
Tongcheng Qian, Shaenah E. Hernday, Xiaoping Bao, Will R Olson +3 more
2019Scientific Reports31 citations Open access
Semantic Scholar
Streptococcus agalactiae disrupts P-glycoprotein function in brain endothelial cells
Brandon J. Kim, Maura A. McDonagh, Li-Wen Deng, Benjamin D. Gastfriend +3 more
2019Fluids and Barriers of the CNS31 citations Open access
Semantic Scholar
Comparative evaluation of isogenic mesodermal and ectomesodermal chondrocytes from human iPSCs for cartilage regeneration
Ming-Song Lee, Matthew J. Stebbins, Hongli Jiao, Hui-Ching Huang +5 more
2021Science Advances29 citations Open access
Semantic Scholar
Engineering an Anti-Transferrin Receptor ScFv for pH-Sensitive Binding Leads to Increased Intracellular Accumulation
B. Tillotson, L. I. Goulatis, Isabelle Parenti, E. Duxbury +1 more
2015PLoS ONE28 citations Open access
Semantic Scholar
Identification of variable lymphocyte receptors that can target therapeutics to pathologically exposed brain extracellular matrix
Benjamin J. Umlauf, P. Clark, J. Lajoie, Julia V Georgieva +4 more
2019Science Advances25 citations Open access
Semantic Scholar
Directed Evolution of Brain-Derived Neurotrophic Factor for Improved Folding and Expression in Saccharomyces cerevisiae
Michael L. Burns, Thomas M. Malott, K. J. Metcalf, B. Hackel +2 more
2014Applied and Environmental Microbiology25 citations Open access
Semantic Scholar
Protein Engineering and High-Throughput Screening by Yeast Surface Display: Survey of Current Methods
Joanan López-Morales, Rosario Vanella, Elizabeth A Appelt, Sarah Whillock +5 more
2023Small Science24 citations Open access
Semantic Scholar
Antibody-targeted liposomes for enhanced targeting of the blood-brain barrier
Zhou Ye, Benjamin D. Gastfriend, Benjamin J. Umlauf, D. M. Lynn +1 more
2022Pharmaceutical Research24 citations Open access
Semantic Scholar
Differentiation of human pluripotent stem cells to brain microvascular endothelial cell-like cells suitable to study immune cell interactions
Hideaki Nishihara, Benjamin D. Gastfriend, Pelin Kasap, S. Palecek +2 more
2021STAR Protocols24 citations Open access
Semantic Scholar
Regional heterogeneity of the blood-brain barrier
Marie Blanchette, Kaja Bajc, Benjamin D. Gastfriend, C. Profaci +19 more
2025Nature Communications23 citations Open access
Semantic Scholar
Integrative analysis of the human brain mural cell transcriptome
Benjamin D. Gastfriend, Koji L. Foreman, Moriah E Katt, S. Palecek +1 more
2021Journal of Cerebral Blood Flow and Metabolism23 citations Open access
Semantic Scholar
Transthyretin Mimetics as Anti-β-Amyloid Agents: A Comparison of Peptide and Protein Approaches
Kayla M. Pate, Brandon J. Kim, Eric V. Shusta, R. Murphy
2018ChemMedChem23 citations Open access
Semantic Scholar
Cryopreservation of Brain Endothelial Cells Derived from Human Induced Pluripotent Stem Cells Is Enhanced by Rho-Associated Coiled Coil-Containing Kinase Inhibition
H. Wilson, Madeline G Faubion, M. Hjortness, S. Palecek +1 more
2016Tissue Engineering. Part C, Methods23 citations Open access
Semantic Scholar
Identifying Blood-Brain Barrier Selective Single-Chain Antibody Fragments
Angela R. Jones, C. C. Stutz, Yu Zhou, J. Marks +1 more
2014Biotechnology Journal23 citations Open access
Semantic Scholar
An Evolved Mxe GyrA Intein for Enhanced Production of Fusion Proteins
C. Marshall, V. Grosskopf, Taylor J Moehling, B. Tillotson +4 more
2014ACS Chemical Biology23 citations Open access
Semantic Scholar
iPSC-derived blood-brain barrier modeling reveals APOE isoform-dependent interactions with amyloid beta
Yun-Feng Ding, S. Palecek, Eric V. Shusta
2024Fluids and Barriers of the CNS22 citations Open access
Semantic Scholar
Directed Evolution of Protein Thermal Stability Using Yeast Surface Display.
Michael W. Traxlmayr, Eric V. Shusta
2017Methods in molecular biology22 citations
Semantic Scholar
Yeast display biopanning identifies human antibodies targeting glioblastoma stem-like cells
M. Żorniak, P. Clark, Benjamin J. Umlauf, Y. Cho +2 more
2017Scientific Reports22 citations Open access
Semantic Scholar
Central nervous system vascularization in human embryos and neural organoids
Sarah M. Boutom, Teresa P. Silva, S. Palecek, Eric V. Shusta +2 more
2024Cell Reports20 citations Open access
Semantic Scholar

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