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A. Choidas · SciRah

Researcher profile · Semantic Scholar

A. Choidas

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A. Choidas — researcher profile on SciRah

h-index: 20
Works: 47
Citations: 3,329

Most-cited papers

Gasdermin D plays a vital role in the generation of neutrophil extracellular traps
G. Sollberger, A. Choidas, G. Burn, P. Habenberger +9 more
2018Science immunology695 citations
Semantic Scholar
The E3 Ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells
M. Paolino, A. Choidas, S. Wallner, Blanka Pranjić +20 more
2014Nature431 citations Open access
Semantic Scholar
Phosphorylation and Free Pool of β-Catenin Are Regulated by Tyrosine Kinases and Tyrosine Phosphatases during Epithelial Cell Migration*
Thomas Müller, A. Choidas, E. Reichmann, A. Ullrich
1999Journal of Biological Chemistry307 citations Open access
Semantic Scholar
Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLC gamma.
A. Obermeier, R. Bradshaw, K. Seedorf, A. Choidas +2 more
1994EMBO Journal298 citations Open access
Semantic Scholar
Small-molecule inhibitors of human mitochondrial DNA transcription
Nina A. Bonekamp, Bradley Peter, H. S. Hillen, Andrea Felser +19 more
2020Nature233 citations
Semantic Scholar
Cloning and Characterization of Secretory Tyrosine Phosphatases of Mycobacterium tuberculosis
A. Koul, A. Choidas, M. Treder, A. Tyagi +3 more
2000Journal of Bacteriology182 citations Open access
Semantic Scholar
Identification of Atuveciclib (BAY 1143572), the First Highly Selective, Clinical PTEFb/CDK9 Inhibitor for the Treatment of Cancer
U. Lücking, A. Scholz, P. Lienau, G. Siemeister +23 more
2017ChemMedChem158 citations Open access
Semantic Scholar
Inhibition of Glucose Transporters and Glutaminase Synergistically Impairs Tumor Cell Growth.
Elena S Reckzeh, George Karageorgis, M. Schwalfenberg, Javier Ceballos +9 more
2019Cell Chemical Biology140 citations Open access
Semantic Scholar
Serine/threonine protein kinases PknF and PknG of Mycobacterium tuberculosis: characterization and localization.
A. Koul, A. Choidas, Anil K. Tyagi, K. Drlica +2 more
2001Microbiology108 citations Open access
Semantic Scholar
Identification of cellular deoxyhypusine synthase as a novel target for antiretroviral therapy.
I. Hauber, D. Bevec, J. Heukeshoven, Friedrich Krätzer +4 more
2005Journal of Clinical Investigation99 citations Open access
Semantic Scholar
The suitability and application of a GFP-actin fusion protein for long-term imaging of the organization and dynamics of the cytoskeleton in mammalian cells.
A. Choidas, A. Jungbluth, Antonio S. Sechi, J. Murphy +2 more
1998European Journal of Cell Biology97 citations
Semantic Scholar
Cell‐type specific phosphorylation of threonines T654 and T669 by PKD defines the signal capacity of the EGF receptor
Christoph P. Bagowski, M. Stein-Gerlach, A. Choidas, A. Ullrich
1999EMBO Journal95 citations Open access
Semantic Scholar
Dynarrestin, a Novel Inhibitor of Cytoplasmic Dynein
Susanne Höing, Ting-Yu Yeh, Matthias Baumann, Nancy E. Martinez +22 more
2018Cell Chemical Biology83 citations Open access
Semantic Scholar
SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemia
Patricia Johansson, L. Klein-Hitpass, A. Choidas, P. Habenberger +11 more
2018Blood Cancer Journal61 citations Open access
Semantic Scholar
Systematic Kinase Inhibitor Profiling Identifies CDK9 as a Synthetic Lethal Target in NUT Midline Carcinoma
J. Brägelmann, Marcel A. Dammert, Felix Dietlein, J. Heuckmann +30 more
2017Cell Reports50 citations Open access
Semantic Scholar
Psoromic acid is a selective and covalent Rab-prenylation inhibitor targeting autoinhibited RabGGTase.
Céline Deraeve, Zhong Guo, R. Bon, W. Blankenfeldt +10 more
2012Journal of the American Chemical Society49 citations
Semantic Scholar
Development of selective, potent RabGGTase inhibitors.
E. A. Stigter, Zhong Guo, R. Bon, Yao-Wen Wu +6 more
2012Journal of Medicinal Chemistry35 citations
Semantic Scholar
Structure-guided development of selective RabGGTase inhibitors.
R. Bon, Zhong Guo, E. A. Stigter, S. Wetzel +7 more
2011Angewandte Chemie22 citations
Semantic Scholar
Discovery of a Novel Inhibitor of the Hedgehog Signaling Pathway through Cell-based Compound Discovery and Target Prediction.
L. Kremer, Carsten Schultz-Fademrecht, Matthias Baumann, P. Habenberger +8 more
2017Angewandte Chemie21 citations
Semantic Scholar
IFNα primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization.
Blaž Andlovic, Geronimo Heilmann, Sabrina Ninck, S. Andrei +13 more
2023Cell Chemical Biology20 citations Open access
Semantic Scholar
Identification of an (−)‐englerin A analogue, which antagonizes (−)‐englerin A at TRPC1/4/5 channels
Hussein N. Rubaiy, Tobias Seitz, Sven Hahn, A. Choidas +7 more
2018British Journal of Pharmacology20 citations Open access
Semantic Scholar
Discovery of N-[4-(Quinolin-4-yloxy)phenyl]benzenesulfonamides as Novel AXL Kinase Inhibitors.
I. Szabadkai, R. Torka, R. Garamvölgyi, F. Baska +6 more
2018Journal of Medicinal Chemistry20 citations Open access
Semantic Scholar
A highly selective purine-based inhibitor of CSF1R potently inhibits osteoclast differentiation.
Thomas Ihle Aarhus, J. Eickhoff, B. Klebl, Anke Unger +7 more
2023European journal of medicinal chemistry17 citations Open access
Semantic Scholar
White Paper: Mimetics of Class 2 Tumor Suppressor Proteins as Novel Drug Candidates for Personalized Cancer Therapy
E. Dahl, S. Villwock, P. Habenberger, A. Choidas +2 more
2022Cancers16 citations Open access
Semantic Scholar
CDK9/cyclin T1: a host cell target for antiretroviral therapy
B. Klebl, A. Choidas
200615 citations
Semantic Scholar
Anti-leukemic effect of CDK9 inhibition in T-cell prolymphocytic leukemia
Patricia Johansson, L. Dierichs, L. Klein-Hitpass, A. Bergmann +8 more
2020Therapeutic Advances in Hematology14 citations Open access
Semantic Scholar
Exploiting features of adenovirus replication to support mammalian kinase production.
M. Cotten, Kerstin Stegmueller, J. Eickhoff, M. Hanke +5 more
2003Nucleic Acids Research13 citations Open access
Semantic Scholar
Definition of Signals for Neuronal Differentiation
A. Obermeier, R. Bradshaw, K. Seedorf, A. Choidas +2 more
1995Annals of the New York Academy of Sciences11 citations
Semantic Scholar
Potent anti-leukemic activity of a specific cyclin-dependent kinase 9 inhibitor in mouse models of chronic lymphocytic leukemia
J. Göthert, R. Imsak, M. Möllmann, S. Kesper +11 more
2018OncoTarget6 citations Open access
Semantic Scholar
Discovery of a Novel Hedgehog Signaling Pathway Inhibitor by Cell-based Compound Discovery and Target Prediction
L. Kremer, Carsten Schultz-Fademrecht, Matthias Baumann, P. Habenberger +8 more
20175 citations
Semantic Scholar
Abstract 2828: Rapid identification of potent and highly selective, oral PTEFb Inhibitor BAY 1143572 with first in class potential
U. Luecking, A. Scholz, P. Lienau, G. Siemeister +20 more
20154 citations
Semantic Scholar
Synthesis, Biological Evaluation, and Binding Mode of a New Class of Oncogenic K‐Ras4b Inhibitors
Stephan Jeuken, Oleksandr Shkura, Marc Röger, Victoria Brickau +7 more
2022ChemMedChem2 citations Open access
Semantic Scholar
Abstract 2997: Dynarrestin, a novel dynein inhibitor that does not block ciliogenesis
Matthias Baumann, Susanne Höing, Ting-Yu Yeh, Nancy E. Martinez +17 more
20162 citations
Semantic Scholar
Abstract 4538: BAY 1112054, a highly selective, potent and orally available inhibitor of PTEFb/CDK9, shows convincing anti-tumor activity
A. Scholz, U. Lücking, G. Siemeister, P. Lienau +15 more
20142 citations
Semantic Scholar
Abstract 2823: Identification of highly selective inhibitors of cyclin-dependent kinase 12
A. Choidas, Carsten Schultz-Fademrecht, Carsten Degeenhardt, P. Habenberger +6 more
20161 citations
Semantic Scholar
Preclinical Testing of a Novel Axl-Kinase Inhibitor in Chronic Lymphocytic Leukemia
Maria Göbel, M. Möllmann, Andre Görgens, U. Duhrsen +5 more
20121 citations
Semantic Scholar
PDE3A-SLFN12 Molecular Glues Target Multiple KIT D816V Cell Types in Preclinical Models of Mast Cell Malignancies
Xuhuang Fu, Anne Kaiser, Payal Chawla, A. Choidas +19 more
2026bioRxiv0 citations Open access
Semantic Scholar
340 (PB328): Discovery of NODX-010, a novel, potent PARG inhibitor demonstrating robust in vivo efficacy and the potential for new clinical settings that benefit patients with tumours resistant to PARP inhibitors
D. James, M. Debunne, J. Engel, A. Unger +8 more
2024European Journal of Cancer0 citations
Semantic Scholar
Abstract 416: A novel non-covalent and rapidly reversible proteasome inhibitor for multiple myeloma and various solid cancers
Wongyun Ahn, Y. Jeon, Yeong-In Yang, Jaeseung C. Kim +9 more
2022Cancer Research0 citations
Semantic Scholar
Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor.
H. S. Hillen, Nina A. Bonekamp, Bradley Peter, Andrea Felser +19 more
20200 citations
Semantic Scholar
CDK9 Inhibition with LDC526 Is an Effective Treatment for T-Cell Prolymphocytic Leukemia (T-PLL) in Vitro
Patricia Johansson, P. Habenberger, L. Klein-Hitpass, U. Duehrsen +4 more
20170 citations
Semantic Scholar
Abstract 1349: Systematic deconvolution of kinase inhibitor profiles identifies synthetic lethal targets in ERBB2-mutant and BRD4-NUT rearranged cancer
J. Braegelmann, P. Habenberger, Felix Dietlein, J. Heuckmann +7 more
20160 citations
Semantic Scholar
Abstract 222: Inhibitors of mitochondrial transcription (IMT) specifically affect cancer cell proliferation
Tim Bergbrede, A. Choidas, Raffaela Di Lucrezia, Sascha Menninger +11 more
20160 citations
Semantic Scholar
Abstract 695: The generation of a mono-selective CDK7 inhibitor.
J. Eickhoff, Gunther Zischinsky, A. Choidas, P. Habenberger +9 more
20130 citations
Semantic Scholar
Screening for Kinase Inhibitors: From Biochemical to Cellular Assays
J. Eickhoff, A. Choidas
20110 citations
Semantic Scholar
, Karl tuberculosis Mycobacterium Tyrosine Phosphatases of Cloning and Characterization of Secretory
A. Koul, A. Choidas, M. Treder, A. Tyagi +3 more
20000 citations
Semantic Scholar
The EMBO Journal: Table of Contents
M. Moore, J. Gulbis, E. Dodson, B. Demple +32 more
19940 citations
Semantic Scholar

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